-
1
-
-
0032934156
-
Functional roles of STAT family proteins: Lessons from knockout mice
-
Akira S. Functional roles of STAT family proteins: lessons from knockout mice. Stem Cells 1999;17:138-46.
-
(1999)
Stem Cells
, vol.17
, pp. 138-146
-
-
Akira, S.1
-
2
-
-
0036731485
-
Stats: Transcriptional control and biological impact
-
Levy DE, Darnell, JE Jr. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002;3:651-62.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr., J.E.2
-
3
-
-
0013689209
-
Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro
-
Grandis JR, Drenning SD, Chakraborty A, et al. Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro. J Clin Investig 1998;102:1385-92.
-
(1998)
J Clin Investig
, vol.102
, pp. 1385-1392
-
-
Grandis, J.R.1
Drenning, S.D.2
Chakraborty, A.3
-
4
-
-
0031443156
-
Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells
-
Garcia R, Yu CL, Hudnall A, et al. Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells. Cell Growth Differ 1997;8:1267-76.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 1267-1276
-
-
Garcia, R.1
Yu, C.L.2
Hudnall, A.3
-
5
-
-
0035799531
-
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
-
Garcia R, Bowman TL, Niu G, et al. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 2001;20:2499-513.
-
(2001)
Oncogene
, vol.20
, pp. 2499-2513
-
-
Garcia, R.1
Bowman, T.L.2
Niu, G.3
-
6
-
-
85047698100
-
Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells
-
Burke WM, Jin X, Lin HJ, et al. Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells. Oncogene 2001;20:7925-34,
-
(2001)
Oncogene
, vol.20
, pp. 7925-7934
-
-
Burke, W.M.1
Jin, X.2
Lin, H.J.3
-
7
-
-
0034163461
-
Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells
-
Ni Z, Lou W, Leman ES, Gao AC. Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells. Cancer Res 2000;60:1225-8.
-
(2000)
Cancer Res
, vol.60
, pp. 1225-1228
-
-
Ni, Z.1
Lou, W.2
Leman, E.S.3
Gao, A.C.4
-
8
-
-
0032852374
-
ErbB-2 kinase is required for constitutive Stat3 activation in malignant human lung epithelial cells
-
Fernandes A, Hamburger AW, Gerwin BI. ErbB-2 kinase is required for constitutive Stat3 activation in malignant human lung epithelial cells. Int. J Cancer 1999;83:564-70.
-
(1999)
Int J Cancer
, vol.83
, pp. 564-570
-
-
Fernandes, A.1
Hamburger, A.W.2
Gerwin, B.I.3
-
9
-
-
0037386568
-
Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth
-
Leong PL, Andrews GA, Johnson DE, et al. Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth. Proc Natl Acad Sci USA 2003;100:4138-43,
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4138-4143
-
-
Leong, P.L.1
Andrews, G.A.2
Johnson, D.E.3
-
12
-
-
0034773992
-
The EGFR family and its ligands in human cancer, signalling mechanisms and therapeutic opportunities
-
Yarden Y. The EGFR family and its ligands in human cancer, signalling mechanisms and therapeutic opportunities. Eur J Cancer 2001;37 Suppl 4:S3-8.
-
(2001)
Eur J Cancer
, vol.37
, Issue.SUPPL. 4
-
-
Yarden, Y.1
-
14
-
-
0034658499
-
STAT signaling in head and neck cancer
-
Song JI, Grandis JR. STAT signaling in head and neck cancer. Oncogene 2000;19:2489-95.
-
(2000)
Oncogene
, vol.19
, pp. 2489-2495
-
-
Song, J.I.1
Grandis, J.R.2
-
15
-
-
0035651001
-
EGFR dependent expression of STAT3 (but not STATI) in breast cancer
-
Berclaz G, Altermatt HJ, Rohrbach V, Siragusa A, Dreher E, Smith PD. EGFR dependent expression of STAT3 (but not STATI) in breast cancer. Int J Oncol 2001;19:1155-60.
-
(2001)
Int J Oncol
, vol.19
, pp. 1155-1160
-
-
Berclaz, G.1
Altermatt, H.J.2
Rohrbach, V.3
Siragusa, A.4
Dreher, E.5
Smith, P.D.6
-
16
-
-
0026729695
-
Multistage carcinogenesis in mouse skin
-
DiGiovanni J. Multistage carcinogenesis in mouse skin. Pharmacol Ther 1992;54:63-128.
-
(1992)
Pharmacol Ther
, vol.54
, pp. 63-128
-
-
DiGiovanni, J.1
-
17
-
-
0028351556
-
The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis - Thirty-third G. H. A. Clowes Memorial Award Lecture
-
Yuspa SH. The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis-thirty-third G. H. A. Clowes Memorial Award Lecture Cancer Res 1994;54:1178-89.
-
(1994)
Cancer Res
, vol.54
, pp. 1178-1189
-
-
Yuspa, S.H.1
-
18
-
-
0028034699
-
Altered expression of the epidermal growth factor receptor and transforming growth factor a during multistage skin carcinogenesis in SENCAR mice
-
Rho O, Beltran LM, Gimenez-Conti IB, DiGiovanni J. Altered expression of the epidermal growth factor receptor and transforming growth factor a during multistage skin carcinogenesis in SENCAR mice. Mol Carcinog 1994;11:19-28.
-
(1994)
Mol Carcinog
, vol.11
, pp. 19-28
-
-
Rho, O.1
Beltran, L.M.2
Gimenez-Conti, I.B.3
DiGiovanni, J.4
-
19
-
-
0028922715
-
Elevation of transforming growth factor α mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis
-
Kiguchi K, Beltran LM, You J, Rho O, DiGiovanni J. Elevation of transforming growth factor α mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis. Mol Carcinog 1995;12:225-35.
-
(1995)
Mol Carcinog
, vol.12
, pp. 225-235
-
-
Kiguchi, K.1
Beltran, L.M.2
You, J.3
Rho, O.4
DiGiovanni, J.5
-
20
-
-
0028874797
-
Activation of the epidermal growth factor receptor by skin tumor promoters and in skin tumors from SENCAR mice
-
Xian W, Kiguchi K, Imamoto A, Rupp T, Zilberstein A, DiGiovanni J. Activation of the epidermal growth factor receptor by skin tumor promoters and in skin tumors from SENCAR mice. Cell Growth Differ 1995;6:1447-55,
-
(1995)
Cell Growth Differ
, vol.6
, pp. 1447-1455
-
-
Xian, W.1
Kiguchi, K.2
Imamoto, A.3
Rupp, T.4
Zilberstein, A.5
DiGiovanni, J.6
-
21
-
-
0031862149
-
Altered expression of epidermal growth factor receptor ligands in tumor promoter-treated mouse epidermis and in primary mouse skin tumors induced by an initiation-promotion protocol
-
Kiguchi K, Beltran L, Rupp T, DiGiovanni J. Altered expression of epidermal growth factor receptor ligands in tumor promoter-treated mouse epidermis and in primary mouse skin tumors induced by an initiation-promotion protocol. Mol Carcinog 1998;22:73-83.
-
(1998)
Mol Carcinog
, vol.22
, pp. 73-83
-
-
Kiguchi, K.1
Beltran, L.2
Rupp, T.3
DiGiovanni, J.4
-
22
-
-
0026668643
-
Transgenic overexpression of transforming growth factor α bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis
-
Vassar R, Hutton ME, Fuchs E. Transgenic overexpression of transforming growth factor α bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis. Mol Cell Biol 1992;12:4643-53.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 4643-4653
-
-
Vassar, R.1
Hutton, M.E.2
Fuchs, E.3
-
23
-
-
0027767476
-
Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas
-
Dominey AM, Wang XJ, King LE Jr, et al. Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas Cell Growth Differ 1993;4:1071-82.
-
(1993)
Cell Growth Differ
, vol.4
, pp. 1071-1082
-
-
Dominey, A.M.1
Wang, X.J.2
King Jr., L.E.3
-
24
-
-
0027931473
-
Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways
-
Jhappan C, Takayama H, Dickson RB, Merlino G. Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways. Cell Growth Differ 1994;5:385-94.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 385-394
-
-
Jhappan, C.1
Takayama, H.2
Dickson, R.B.3
Merlino, G.4
-
25
-
-
0028332305
-
Epidermal expression of transforming growth factor α in transgenic mice: Induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression
-
Wang XJ, Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop DR. Epidermal expression of transforming growth factor α in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression. Mol Carcinog 1994;10:15-22,
-
(1994)
Mol Carcinog
, vol.10
, pp. 15-22
-
-
Wang, X.J.1
Greenhalgh, D.A.2
Eckhardt, J.N.3
Rothnagel, J.A.4
Roop, D.R.5
-
26
-
-
0037096880
-
A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis
-
Casanova ML, Larcher F, Casanova B, et al. A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis. Cancer Res 2002;62:3402-7.
-
(2002)
Cancer Res
, vol.62
, pp. 3402-3407
-
-
Casanova, M.L.1
Larcher, F.2
Casanova, B.3
-
27
-
-
0030755457
-
Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras
-
Dlugosz, AA, Hansen, L, Cheng, C, et al. Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras Cancer Res 1997;57:3180-8.
-
(1997)
Cancer Res
, vol.57
, pp. 3180-3188
-
-
Dlugosz, A.A.1
Hansen, L.2
Cheng, C.3
-
28
-
-
0023277958
-
Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice
-
Kruszewski FH, Conti CJ, DiGiovanni J. Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice. Cancer Res 1987;47:3783-90.
-
(1987)
Cancer Res
, vol.47
, pp. 3783-3790
-
-
Kruszewski, F.H.1
Conti, C.J.2
DiGiovanni, J.3
-
29
-
-
0030891767
-
Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: Possible role in mouse skin tumor promotion
-
Xian W, Rosenberg MP, DiGiovanni J. Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: possible role in mouse skin tumor promotion. Oncogene 1997;14:1435-44.
-
(1997)
Oncogene
, vol.14
, pp. 1435-1444
-
-
Xian, W.1
Rosenberg, M.P.2
DiGiovanni, J.3
-
30
-
-
0033198793
-
Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis
-
Sano S, Itami S, Takeda K, et al. Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis. EMBO J 1999;18:4657-68.
-
(1999)
EMBO J
, vol.18
, pp. 4657-4668
-
-
Sano, S.1
Itami, S.2
Takeda, K.3
-
31
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.) 1970;227:680-5.
-
(1970)
Nature (Lond.)
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
33
-
-
0024121562
-
Okadaic acid: An additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter
-
Suganuma M, Fujiki H, Suguri H, et al. Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter. Proc Natl Acad Sci USA 1988;85:1768-71.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 1768-1771
-
-
Suganuma, M.1
Fujiki, H.2
Suguri, H.3
-
34
-
-
0030801361
-
Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site
-
Arteaga CL, Ramsey TT, Shawver LK, Guyer CA. Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site. J Biol Chem 1997;272:23247-54.
-
(1997)
J Biol Chem
, vol.272
, pp. 23247-23254
-
-
Arteaga, C.L.1
Ramsey, T.T.2
Shawver, L.K.3
Guyer, C.A.4
-
35
-
-
0028784049
-
Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure
-
Murillas R, Larcher F, Conti CJ, Santos M, Ullrich A, Jorcano JL. Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure. EMBO J 1995;14:5216-23.
-
(1995)
EMBO J
, vol.14
, pp. 5216-5223
-
-
Murillas, R.1
Larcher, F.2
Conti, C.J.3
Santos, M.4
Ullrich, A.5
Jorcano, J.L.6
-
36
-
-
0030447148
-
In vitro activation of Stat3 by epidermal growth factor receptor kinase
-
Park OK, Schaefer TS, Nathans D. In vitro activation of Stat3 by epidermal growth factor receptor kinase. Proc Natl Acad Sci USA 1996;93:13704-8.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13704-13708
-
-
Park, O.K.1
Schaefer, T.S.2
Nathans, D.3
-
37
-
-
0037163125
-
Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation
-
Xia L, Wang L, Chung AS, et al. Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation. J Biol Chem 2002;277:30716-23.
-
(2002)
J Biol Chem
, vol.277
, pp. 30716-30723
-
-
Xia, L.1
Wang, L.2
Chung, A.S.3
-
38
-
-
0023880172
-
Protein kinase C as the receptor for the phorbol ester tumor promoters: Sixth Rhoads memorial award lecture
-
Blumberg PM. Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture. Cancer Res 1988;48:1-8.
-
(1988)
Cancer Res
, vol.48
, pp. 1-8
-
-
Blumberg, P.M.1
-
40
-
-
0033607029
-
Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis
-
Waikel RL, Wang XJ, Roop DR. Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene 1999;18:4870-8.
-
(1999)
Oncogene
, vol.18
, pp. 4870-4878
-
-
Waikel, R.L.1
Wang, X.J.2
Roop, D.R.3
-
41
-
-
0035901594
-
c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
-
Arnold 1, Watt FM. c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol 2001;11:558-68.
-
(2001)
Curr Biol
, vol.11
, pp. 558-568
-
-
Arnold, I.1
Watt, F.M.2
-
43
-
-
0032789831
-
Cyclin D1 overexpression in mouse epidermis increases cyclin-dependent kinase activity and cell proliferation in vivo but does not affect skin tumor development
-
Rodriguez-Puebla ML, LaCava M, Conti CJ. Cyclin D1 overexpression in mouse epidermis increases cyclin-dependent kinase activity and cell proliferation in vivo but does not affect skin tumor development. Cell Growth Differ 1999;10:467-72.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 467-472
-
-
Rodriguez-Puebla, M.L.1
LaCava, M.2
Conti, C.J.3
-
44
-
-
0037086276
-
Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice: Cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation
-
Yamamoto H, Ochiya T, Takeshita F, et al. Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice: cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation. Cancer Res 2002;62:1641-7.
-
(2002)
Cancer Res
, vol.62
, pp. 1641-1647
-
-
Yamamoto, H.1
Ochiya, T.2
Takeshita, F.3
-
45
-
-
0028005372
-
Keratinocyte growth factor receptor ligands induce transforming growth factor alpha expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes
-
Dlugosz AA, Cheng C, Denning MF, Dempsey PJ, Coffey, RJ Jr, Yuspa SH. Keratinocyte growth factor receptor ligands induce transforming growth factor alpha expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes Cell Growth Differ 1994;5:1283-92.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 1283-1292
-
-
Dlugosz, A.A.1
Cheng, C.2
Denning, M.F.3
Dempsey, P.J.4
Coffey Jr., R.J.5
Yuspa, S.H.6
-
47
-
-
0026096448
-
Promoter independence as a feature of most skin papillomas in SENCAR mice
-
Aldaz CM, Conti CJ, Chen A, Bianchi A, Walker SB, DiGiovanni J. Promoter independence as a feature of most skin papillomas in SENCAR mice. Cancer Res 1991;51:1045-50.
-
(1991)
Cancer Res
, vol.51
, pp. 1045-1050
-
-
Aldaz, C.M.1
Conti, C.J.2
Chen, A.3
Bianchi, A.4
Walker, S.B.5
DiGiovanni, J.6
-
48
-
-
0032523237
-
A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas
-
Pena JC, Rudin CM, Thompson CB. A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas. Cancer Res 1998;58:2111-6.
-
(1998)
Cancer Res
, vol.58
, pp. 2111-2116
-
-
Pena, J.C.1
Rudin, C.M.2
Thompson, C.B.3
-
49
-
-
0037081097
-
Overexpression of vascular endothelial growth factor-A165 enhances tumor angiogenesis but not metastasis during β-cell carcinogenesis
-
Gannon G, Mandriota SJ, Cui L, Baetens D, Pepper MS, Christofori G. Overexpression of vascular endothelial growth factor-A165 enhances tumor angiogenesis but not metastasis during β-cell carcinogenesis. Cancer Res 2002;62:603-8.
-
(2002)
Cancer Res
, vol.62
, pp. 603-608
-
-
Gannon, G.1
Mandriota, S.J.2
Cui, L.3
Baetens, D.4
Pepper, M.S.5
Christofori, G.6
-
50
-
-
0032560844
-
VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development
-
Larcher F, Murillas R, Bolontrade M, Conti CJ, Jorcano JL. VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development. Oncogene 1998;17:303-11.
-
(1998)
Oncogene
, vol.17
, pp. 303-311
-
-
Larcher, F.1
Murillas, R.2
Bolontrade, M.3
Conti, C.J.4
Jorcano, J.L.5
-
51
-
-
0023626472
-
Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents
-
Naito M, Naito Y, DiGiovanni J. Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents. Carcinogenesis (Lond.) 1987;8:1807-15.
-
(1987)
Carcinogenesis (Lond.)
, vol.8
, pp. 1807-1815
-
-
Naito, M.1
Naito, Y.2
DiGiovanni, J.3
|