Oxygen Activation by the Noncoupled Binuclear Copper Site in Peptidylglycine α-Hydroxylating Monooxygenase. Reaction Mechanism and Role of the Noncoupled Nature of the Active Site

Journal of the American Chemical Society

Volumn 126, Issue 15, 2004, Pages 4991-5000

  Chen, Peng ^a   Solomon, Edward I ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CATALYSIS; COPPER; ELECTRONS; GLYCEROL; HYDROXYLATION; ORGANOMETALLICS; THERMODYNAMICS;

CATECHOL OXIDASE; H-ATOM ABSTRACTION; HEMOCYANIN; TYROSINASE;

OXYGEN;

CARBOXYL GROUP; CATECHOL OXIDASE; COPPER; DOPAMINE BETA MONOOXYGENASE; HEMOCYANIN; HYDROGEN; MONOPHENOL MONOOXYGENASE; OXYGEN; PEPTIDYLGLYCINE ALPHA HYDROXYLATING MONOOXYGENASE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CALCULATION; ELECTRON TRANSPORT; ENERGY; ENERGY TRANSFER; ENZYME ACTIVE SITE; HYDROXYLATION; MOLECULAR INTERACTION; REACTION ANALYSIS; SPECIES; THERMODYNAMICS;

BINDING SITES; COMPUTATIONAL BIOLOGY; COPPER; MIXED FUNCTION OXYGENASES; MODELS, CHEMICAL; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; OXYGEN; THERMODYNAMICS;

EID: 1942504122     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja031564g     Document Type: Article

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