Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 10, 2004, Pages 2559-2562

  Jahng, Yurngdong ^a   Zhao, Long Xuan ^b   Moon, Yoon Soo ^a   Basnet, Arjun ^a   Kim, Eun Kyung ^a   Chang, Hyeun Wook ^a   Ju, Hye Kyung ^a   Jeong, Tae Cheon ^a   Lee, Eung Seok ^a  

^a Yeungnam University   (South Korea)

^b LIAONING NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; AROMATIC COMPOUND; LIPOXYGENASE INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR;

ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONATE 5-LIPOXYGENASE; BONE MARROW CELLS; CYCLOOXYGENASE INHIBITORS; DRUG DESIGN; ENZYME INHIBITORS; HYDROCARBONS, AROMATIC; INHIBITORY CONCENTRATION 50; KETONES; MALE; MICE; MICE, INBRED BALB C; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1942438483     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.099     Document Type: Article

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