-
1
-
-
0030755036
-
In vivo pharmacokinetics of phosphorothioate oligonucleotides containing contiguous guanosines
-
AGRAWAL, S., TAN, W., CAI, Q., XIE, X., and ZHANG, R. (1997). In vivo pharmacokinetics of phosphorothioate oligonucleotides containing contiguous guanosines. Antisense Nucleic Acid Drug Dev. 7, 245-249.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 245-249
-
-
Agrawal, S.1
Tan, W.2
Cai, Q.3
Xie, X.4
Zhang, R.5
-
2
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
ALTSCHUL, S.F., MADDEN, T.L., SCHAFFER, A.A., ZHANG, J., ZHANG, Z., MILLER, W., and LIPMAN, D.J. (1997). Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25, 3389-3402.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
3
-
-
0030806663
-
Characterization and modulation of immune stimulation by modified oligonucleotides
-
BOGGS, R.T., McGRAW, K.K., CONDON, T., FLOURNOY, S., VILLIET, P., BENNETT, C.F., and MONIA, B.P. (1997). Characterization and modulation of immune stimulation by modified oligonucleotides. Antisense Nucleic Acid Drug Dev. 7, 461-471.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 461-471
-
-
Boggs, R.T.1
McGraw, K.K.2
Condon, T.3
Flournoy, S.4
Villiet, P.5
Bennett, C.F.6
Monia, B.P.7
-
4
-
-
0033903187
-
Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines
-
DEFAZIO, A., CHIEW, Y.E., SINI, R.L., JANES, P.W., and SUTHERLAND, R.L. (2000). Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines. Int. J. Cancer 87, 487-498.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 487-498
-
-
Defazio, A.1
Chiew, Y.E.2
Sini, R.L.3
Janes, P.W.4
Sutherland, R.L.5
-
5
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
-
GUVAKOVA, M.A., YAKUBOV, L.A., VLODAVSKY, I., TONKINSON, J.L., and STEIN, C.A. (1995). Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J. Biol. Chem. 270, 2620-2627.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkinson, J.L.4
Stein, C.A.5
-
6
-
-
0034142182
-
Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
-
HARTMANN, G., WEERATNA, R.D., BALLAS, Z.K., PAYETTE, P., BLACKSWELL, S., SUPARTO, I., RASMUSSEN, W.L., WALDSCMITT, M., SAJUTHI, D., PURCELL, R.H., DAVIDS, H.L., and KRIEG, A.M. (2000). Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J. Immunol. 164, 1617-1624.
-
(2000)
J. Immunol.
, vol.164
, pp. 1617-1624
-
-
Hartmann, G.1
Weeratna, R.D.2
Ballas, Z.K.3
Payette, P.4
Blackswell, S.5
Suparto, I.6
Rasmussen, W.L.7
Waldscmitt, M.8
Sajuthi, D.9
Purcell, R.H.10
Davids, H.L.11
Krieg, A.M.12
-
7
-
-
0037407691
-
Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells
-
KERKMANN, M., ROTHENFUSSER, S., HORNUNG, V., TOWAROWSKI, A., WAGNER, M., SARRIS, A., GIESE, T., ENDRES, S., and HARTMANN, G. (2003). Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J. Immunol. 170, 4465-4474.
-
(2003)
J. Immunol.
, vol.170
, pp. 4465-4474
-
-
Kerkmann, M.1
Rothenfusser, S.2
Hornung, V.3
Towarowski, A.4
Wagner, M.5
Sarris, A.6
Giese, T.7
Endres, S.8
Hartmann, G.9
-
8
-
-
0032720361
-
Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides
-
KRIEG, A.M. (1999). Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides. Biochim. Biophys. Acta 1489, 107-116.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 107-116
-
-
Krieg, A.M.1
-
9
-
-
0029811432
-
Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs
-
KRIEG, A.M., MATSON, S., and FISHER, E. (1996). Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs. Antisense Nucleic Acid Drug Dev. 6, 133-139.
-
(1996)
Antisense Nucleic Acid Drug Dev.
, vol.6
, pp. 133-139
-
-
Krieg, A.M.1
Matson, S.2
Fisher, E.3
-
10
-
-
0018083331
-
Isolation of two human tumor epithelial cell lines from solid breast carcinomas
-
LASFARGUES, E.Y., COUTINHO, W.G., and REDFIELD, E.S. (1978). Isolation of two human tumor epithelial cell lines from solid breast carcinomas. J. Natl. Cancer Inst. 61, 967-978.
-
(1978)
J. Natl. Cancer Inst.
, vol.61
, pp. 967-978
-
-
Lasfargues, E.Y.1
Coutinho, W.G.2
Redfield, E.S.3
-
11
-
-
0032697942
-
A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides
-
LEVIN, A.A. (1999). A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim. Biophys. Acta 1489, 69-84.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 69-84
-
-
Levin, A.A.1
-
12
-
-
0027228277
-
Current concepts in antisense drug design
-
MILLIGAN, J.F., MATTEUCCI, M.D., and MARTIN, J.C. (1993). Current concepts in antisense drug design. J. Med. Chem. 36, 1923-1937.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 1923-1937
-
-
Milligan, J.F.1
Matteucci, M.D.2
Martin, J.C.3
-
13
-
-
0027368461
-
What makes an mRNA anti-sense-itive?
-
NELLEN, W., and LICHTENSTEIN, C. (1993). What makes an mRNA anti-sense-itive?, Trends Biochem. Sci. 18, 419-423.
-
(1993)
Trends Biochem. Sci.
, vol.18
, pp. 419-423
-
-
Nellen, W.1
Lichtenstein, C.2
-
14
-
-
0032445260
-
HER-2/neu as a predictive marker of response to breast cancer therapy
-
PEGRAM, M.D., PAULETTI, G., and SLAMON, D.J. (1998). HER-2/neu as a predictive marker of response to breast cancer therapy. Breast Cancer Res. Treat. 52, 65-77.
-
(1998)
Breast Cancer Res. Treat.
, vol.52
, pp. 65-77
-
-
Pegram, M.D.1
Pauletti, G.2
Slamon, D.J.3
-
15
-
-
0031904608
-
Antisense oligonucleotides specific for the HER2/neu oncogene inhibit the growth of human breast carcinoma cells that overexpress HER2/neu
-
ROH, H., PIPPIN, J., BOSWELL, C., and DREBIN, J.A. (1998). Antisense oligonucleotides specific for the HER2/neu oncogene inhibit the growth of human breast carcinoma cells that overexpress HER2/neu. J. Surg. Res. 77, 85-90.
-
(1998)
J. Surg. Res.
, vol.77
, pp. 85-90
-
-
Roh, H.1
Pippin, J.2
Boswell, C.3
Drebin, J.A.4
-
16
-
-
0007094435
-
CpG-oligonukleotide: Immuntherapie nach dem Muster der bakteriellen DNA
-
ROTHENFUSSER, S., JAHRSDOERFER. B., KRUG, A., ENDRES, S., and HARTMANN, G. (2001). CpG-oligonukleotide: Immuntherapie nach dem Muster der bakteriellen DNA. Deutsches Ärzteblatt 98, A 981-985.
-
(2001)
Deutsches Ärzteblatt
, vol.98
-
-
Rothenfusser, S.1
Jahrsdoerfer, B.2
Krug, A.3
Endres, S.4
Hartmann, G.5
-
17
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
SLAMON, D.J., CLARK, G.M., WONG, S.G., LEVIN, W.J., ULLRICH, A., and McGUIRE, W.L. (1987). Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235, 177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
18
-
-
0021148470
-
Automated solid-phase synthesis, separation and stereochemistry of phosphorothioate analogues of oligodeoxynucleotides
-
STEC, W.J., ZON, G., EGA, W., and STEC, B. (1984). Automated solid-phase synthesis, separation and stereochemistry of phosphorothioate analogues of oligodeoxynucleotides. J. Am. Chem. Soc. 106, 6077-6089.
-
(1984)
J. Am. Chem. Soc.
, vol.106
, pp. 6077-6089
-
-
Stec, W.J.1
Zon, G.2
Ega, W.3
Stec, B.4
-
19
-
-
0029943679
-
Phosphorothioate antisense oligodeoxynucleotides: Questions of specificity
-
STEIN, C.A. (1996). Phosphorothioate antisense oligodeoxynucleotides: Questions of specificity. Trends Biotechnol. 14, 147-149.
-
(1996)
Trends Biotechnol.
, vol.14
, pp. 147-149
-
-
Stein, C.A.1
-
20
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
-
STEIN, C.A., and CHENG, Y.C. (1993). Antisense oligonucleotides as therapeutic agents - Is the bullet really magical? Science 261, 1004-1012.
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
Stein, C.A.1
Cheng, Y.C.2
-
21
-
-
0017028638
-
Human breast cancer in culture
-
TREMPE, G.L. (1976). Human breast cancer in culture. Recent Results Cancer Res. 57, 33-41.
-
(1976)
Recent Results Cancer Res.
, vol.57
, pp. 33-41
-
-
Trempe, G.L.1
-
22
-
-
0032549036
-
The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: From orphanhood to multiple stromal ligands
-
TZAHAR, E., and YARDEN, Y. (1998). The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: From orphanhood to multiple stromal ligands. Biochim. Biophys. Acta 1377, M25-37.
-
(1998)
Biochim. Biophys. Acta
, vol.1377
-
-
Tzahar, E.1
Yarden, Y.2
-
23
-
-
0030830147
-
Studies on the mechanism of stabilization of partially phosphorothioated oligonucleotides against nucleolytic degradation
-
UHLMANN, E., RYTE, A., and PEYMAN, A. (1997). Studies on the mechanism of stabilization of partially phosphorothioated oligonucleotides against nucleolytic degradation. Antisense Nucleic Acid Drug Dev. 7, 345-350.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 345-350
-
-
Uhlmann, E.1
Ryte, A.2
Peyman, A.3
-
24
-
-
0029145127
-
Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay
-
VAUGHN, J.P., IGELHART, J.D., DEMIRJI, S., DAVIS, P., BABISS, L.E., CARUTHERS, M.H., and MARKS, J.R. (1995). Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay. Proc. Natl. Acad. Sci. USA 92, 8338-8342.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8338-8342
-
-
Vaughn, J.P.1
Igelhart, J.D.2
Demirji, S.3
Davis, P.4
Babiss, L.E.5
Caruthers, M.H.6
Marks, J.R.7
-
25
-
-
0029993882
-
Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides
-
VAUGHN, J.P., STEKLER, J., DEMIRJI, S., MILLS, J.K., CARUTHERS, M.H., IGELHART, J.D., and MARKS, J.R. (1996). Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides. Nucleic Acids Res. 24, 4558-4564.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 4558-4564
-
-
Vaughn, J.P.1
Stekler, J.2
Demirji, S.3
Mills, J.K.4
Caruthers, M.H.5
Igelhart, J.D.6
Marks, J.R.7
-
26
-
-
0035900673
-
Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides
-
XU, X., HAMOUIYA, F., THOMAS, S.D., BURKE, T.J., GIRVAN, A.C., McGREGOR, W.G., TRENT, J.O., MILLER, D.M., and BATES, P.J. (2001). Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides. J. Biol. Chem. 276, 43221-43230.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43221-43230
-
-
Xu, X.1
Hamouiya, F.2
Thomas, S.D.3
Burke, T.J.4
Girvan, A.C.5
McGregor, W.G.6
Trent, J.O.7
Miller, D.M.8
Bates, P.J.9
-
27
-
-
0030779241
-
Cationic polyhexylcyanoacrylate nanoparticles as carriers for antisense oligonucleotides
-
ZOBEL, H.P., KREUTER, J., WERNER, D., NOE, C.R., KUMEL, G., and ZIMMER, A. (1997). Cationic polyhexylcyanoacrylate nanoparticles as carriers for antisense oligonucleotides. Antisense Nucleic Acid Drug Dev. 7, 483-493.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 483-493
-
-
Zobel, H.P.1
Kreuter, J.2
Werner, D.3
Noe, C.R.4
Kumel, G.5
Zimmer, A.6
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