Characterization and modulation of immune stimulation by modified oligonucleotides

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 5, 1997, Pages 461-471

  Boggs, Russell T ^a   McGraw, Kathy ^a   Condon, Tom ^a   Flournoy, Shin ^a   Villiet, Pierre ^a   Frank Bennett, C ^a   Monia, Brett P ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; CYTOSINE DERIVATIVE; OLIGODEOXYNUCLEOTIDE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA SEQUENCE; IMMUNOSTIMULATION; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; MURINAE;

EID: 0030806663     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.461     Document Type: Article

References (3)

1. BALLAS, Z., RASMUSSEN, W., and KRIEG, A. (1996). Induction of natural killer activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J. Immunol. 157, 1840-1845.
2. BENNETT, C., CHIANG, M.-Y., CHAN, H., SHOEMAKER, J., and MIRABELLI, C. (1992). Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. 41, 1023-1033.
3. YOKOYAMA, W., KONIG, F., KEHN, P., PEREIRA, G., STINGL, G., COLIGAN, J., and SHEVACH, E. (1988). Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J. Immunol. 141, 369-376.