Increased susceptibility of fat-laden Zucker-rat hepatocytes to bile acid-induced oncotic necrosis: An in vitro model of steatocholestasis

Journal of Laboratory and Clinical Medicine

Volumn 145, Issue 5, 2005, Pages 247-262

  Kobak, Gregory E ^b   Dahl, Rolf ^b   Devereaux, Michael W ^b   Gumpricht, Eric ^b   Traber, Maret ^b   Doctor, R Brian ^b   Sokol, Ronald J ^a  

^a CHILDREN S HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA TOCOPHEROL; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; BETA CAROTENE; BILE ACID; CYTOCHROME C; GLYCOCHENODEOXYCHOLIC ACID; IDEBENONE; REACTIVE OXYGEN METABOLITE; TROLOX C; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL ISOLATION; CELL SUSPENSION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE MODEL; DISEASE PREDISPOSITION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFECT; EXPOSURE; FATTY LIVER; IN VITRO STUDY; INTRAHEPATIC CHOLESTASIS; LEAN BODY WEIGHT; LIVER CELL; LIVER MITOCHONDRION; LIVER PROTECTION; MALE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NONHUMAN; OBESITY; PROTEIN SECRETION; PURIFICATION; RAT; RAT STRAIN; STIMULATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BILE ACIDS AND SALTS; CASPASES; CELL MEMBRANE PERMEABILITY; CYTOCHROMES C; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FATTY LIVER; GLYCOCHENODEOXYCHOLIC ACID; HEPATOCYTES; MALE; MITOCHONDRIA, LIVER; NECROSIS; NUTRITIONAL STATUS; OBESITY; RATS; RATS, ZUCKER; REACTIVE OXYGEN SPECIES;

EID: 19344366888     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lab.2004.12.007     Document Type: Article

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