Extended-duration analgesia: Update on microspheres and liposomes

Regional Anesthesia and Pain Medicine

Volumn 30, Issue 3, 2005, Pages 275-285

  Rose, Julie S ^a   Neal, Joseph M ^a,b   Kopacz, Dan J ^a  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ALFENTANIL; BUPIVACAINE; DEXAMETHASONE; LIDOCAINE; LIPOSOME; LOCAL ANESTHETIC AGENT; MICROSPHERE; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; POLYGLACTIN; TETRODOTOXIN;

ACIDITY; CHEMICAL STRUCTURE; CONTROLLED DRUG RELEASE; DIAPHRAGM PARALYSIS; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG MANUFACTURE; DRUG METABOLISM; DRUG RELEASE; DRUG TOLERABILITY; FIRST PASS EFFECT; HUMAN; HYPOTENSION; MUSCLE WEAKNESS; NEUROTOXICITY; NONHUMAN; PH MEASUREMENT; POSTOPERATIVE ANALGESIA; PRIORITY JOURNAL; REVIEW; STRUCTURE ANALYSIS; SUSTAINED DRUG RELEASE;

ANESTHETICS, LOCAL; ANIMALS; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; HUMANS; LIPOSOMES; MICROSPHERES; PARTICLE SIZE;

EID: 19344364890     PISSN: 10987339     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rapm.2005.01.004     Document Type: Review

References (64)

1. A. Borgeat, G. Ekatodramis, C.A. Schenker Postoperative nausea and vomiting in regional anesthesia. A review Anesthesiology 98 2003 530 547
2. M.F. Mulroy, K.L. Larkin, M.S. Batra, P.S. Hodgson, B.D. Owens Femoral nerve block with 0.25% or 0.5% bupivacaine improves postoperative analgesia following outpatient arthroscopic anterior cruciate ligament repair Reg Anesth Pain Med 26 2001 24 29
3. J.M. Neal, J.R. Hebl, J.C. Gerancher, Q.H. Hogan Brachial plexus anesthesia Essentials of our current understanding Reg Anesth Pain Med 27 2002 402 428
4. B.M. Ilfeld, D.E. Esener, T.E. Morey, F.K. Enneking Ambulatory perineural infusion The patients' perspective Reg Anesth Pain Med 28 2003 418 423
5. P. Lipfert, R.J. Seitz, J.O. Amdt Ultralong-lasting nerve block Triethyldodecyl ammonium bromide is probably a neurotoxin rather than a local anesthetic Anesthesiology 67 1987 896 904
6. J.E. Scurlock, B.M. Curtis Tetraethylammonium derivatives Ultralong-acting local anesthetics Anesthesiology 54 1981 265 269
7. R. Langer New methods of drug delivery Science 249 1990 1527 1533
8. D.B. Masters, C.B. Berde, S.K. Dutta, C.T. Griggs, D. Hu, W. Kupsky, R. Langer Prolonged regional nerve blockade by controlled release of local anesthetic from a biodegradable polymer matrix Anesthesiology 79 1993 340 346
9. H.H.M. Korsten, E.W. Ackerman, R.J.E. Grouls, A.A.J. Van Zundert, W.N. Boon, F. Bal, M.A. Crommelin, J.G. Ribot, F. Hoefsloot, J.L. Slooff Long-lasting epidural sensory blockade by n-butyl-p-aminobenzoate in the terminally ill intractable cancer patient Anesthesiology 75 1991 950 960
10. L. Langerman, E. Golomb, S. Benita Spinal anesthesia Significant prolongation of the pharmacologic effect of tetracaine with lipid solution of the agent Anesthesiology 74 1991 105 107
11. J.R. Mhando, A. Li Wan Po Controlled release of local anesthetic agents from liquid-solid emulsion gels Int J Pharm (Amst) 80 1990 249 258
12. L. Bonhomme, D. Benhamou, T. Beugre Slow-release effect of pH-adjusted bupivacaine In vitro demonstration Int J Pharm 84 1992 33 37
13. J.-P. Estebe, R.R. Myers Amitriptyline neurotoxicity. Dose-related pathology after topical application to rat sciatic nerve Anesthesiology 100 2004 1519 1525
14. P. Gerner Tricyclic antidepressants and their local anesthetic properties From bench to bedside and back again Reg Anesth Pain Med 29 2004 286 289
15. D.S. Kohane, S.E. Smith, D.N. Louis, G. Colombo, P. Ghoroghchian, N.G.M. Hunfeld, C.S. Berde, R. Langer Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres Pain 104 2003 415 421
16. D.S. Kohane, N.T. Lu, A.C. Gokgol-Kline, M. Shubina, Y. Kuang, S. Hall, G.R. Strichartz, C.B. Berde The local anesthetic properties and toxicity of saxitonin homologues for rat sciatic nerve block in vivo Reg Anesth Pain Med 25 2000 52 59
17. P. Le Corre, P. Le Guevello, V. Gajan, F. Chevanne, R. Le Verge Preparation and characterization of bupivacaine-loaded polylactide and polylactide-co-glycolide microspheres Int J Pharm 107 1994 41 49
18. J. Curley, J. Castillo, J. Hotz, M. Uezono, S. Hernandez, J.-O. Lim, J. Tigner, M. Chasin, R. Langer, C. Berde Prolonged regional nerve block. Injectable biodegradable bupivacaine/polyester microspheres Anesthesiology 84 1996 1401 1410
19. J.M. Malinovsky, J.M. Bernard, P. Le Corre, J.B. Dumand, J.Y. Lepage, R. Le Verge, R. Souron Motor and blood pressure effects of epidural sustained-release bupivacaine from polymer microspheres A dose-response study in rabbits Anesth Analg 81 1995 519 524
20. J.P. Estebe, P. Le Corre, Y. Malledant, F. Chevanne, R. Leverge Prolongation of spinal anesthesia with bupivacaine-loaded (DL-Lactide) microspheres Anesth Analg 81 1995 99 103
21. D.J. Kopacz, P.G. Lacouture, D. Wu, P. Nandy, R. Swanton, C. Landau The dose response and effects of dexamethasone on bupivacaine microcapsules for intercostal block (T9-T11) in healthy volunteers Anesth Analg 96 2003 576 582
22. D.J. Kopacz, C.M. Bernards, H.W. Allen, C. Landau, P. Nandy, P.G. Lacouture A model to evaluate the pharmacokinetic and pharmacodynamic variables of extended-release products using in vivo tissue microdialysis in humans Bupivacaine-loaded microspheres Anesth Analg 97 2003 124 131
23. J.L. Pedersen, J. Lilleso, N.A. Hammer, M.U. Werner, K. Holte, P.G. Lacouture, H. Kehlet Bupivacaine in microcapsules prolongs analgesia after subcutaneous infiltration in humans A dose-finding study Anesth Analg 99 2004 912 918
24. J. Castillo, J. Curley, J. Hotz, M. Uezono, J. Tigner, M. Chasin, R. Wilder, R. Langer, C. Berde Glucocorticoids prolong rat sciatic nerve blockade in vivo from bupivacaine microspheres Anesthesiology 85 1996 1157 1166
25. C. Drager, D. Benziger, F. Gao, C.B. Berde Prolonged intercostal nerve blockade in sheep using controlled-release of bupivacaine and dexamethasone from polymer microspheres Anesthesiology 89 1998 969 979
26. K. Holte, M.U. Werner, P.G. Lacouture, H. Kehlet Dexamethasone prolongs local analgesia after subcutaneous infiltration of bupivacaine microspheres in human volunteers Anesthesiology 96 2002 1331 1335
27. D.S. Kohane, J. Yieh, N.T. Lu, R. Langer, G.R. Strichartz, C.B. Berde A re-examination of tetrodotoxin for prolonged duration local anesthesia Anesthesiology 89 1998 119 131
28. J.P. Estebe, P. Le Corre, L. Du Plessis, F. Chevanne, G. Cathelineau, R. Le Verge, C. Ecoffey The pharmacokinetics and pharmacodynamics of bupivacaine-loaded microspheres on a brachial plexus block model in sheep Anesth Analg 93 2001 447 455
29. D. Fletcher, P. Le Corre, G. Guilbaud, R. Le Verge Antinociceptive effect of bupivacaine encapsulated in poly (D,L)-lactide co-glycolide microspheres in the acute inflammatory model of carrageenin-injected rats Anesth Analg 84 1997 90 94
30. J.-P. Estebe, M.E. Gentili, P. Le Corre, R. Le Verge, J.P. Moulinoux, C. Ecoffey Sciatic nerve block with bupivacaine-loaded microspheres prevents hyperalgesia in an inflammatory animal model Can J Anaesth 49 2002 690 693
31. K. Yamaguchi, J.M. Anderson In vivo biocompatibility of medisorb 65/35 D, L lactide, gylcolid copolymer microspheres J Cont Rel 24 1993 81 93
32. J.M. Anderson, M.S. Shive Biodegradation and biocompatibility of PLA and PLGA microspheres Adv Drug Deliv Rev 28 1997 5 24
33. J.M. Neal Effects of epinephrine in local anesthetics on the central and peripheral nervous systems Neurotoxicity and neural blood flow Reg Anesth Pain Med 28 2003 124 134
34. R.K. Gupta Drug targeting in cancer chemotherapy A clinical perspective J Pharm Sci 79 1990 949 963
35. T. Mashimo, I. Uchida, M. Pak, A. Shibata, S. Nishimura, Y. Inagaki, I. Yoshiya Prolongation of canine epidural anesthesia by liposome encapsulation of lidocaine Anesth Analg 74 1992 827 834
36. G. Gregoriadis, A.T. Florence Liposomes in drug delivery. Clinical, diagnostic and ophthalmic potential Drugs 45 1993 15 28
37. G.J. Grant, K. Vermeulen, M.I. Zabowski, M. Stenner, H. Turndorf, L. Langerman Prolonged analgesia and decreased toxicity with liposomal morphine in a mouse model Anesth Analg 79 1994 706 709
38. G.J. Grant, Y. Barenholz, E.M. Bolotin, M. Bansinath, H. Turndorf, B. Piskoun, E.M. Davidson A novel liposomal bupivacaine formulation to produce ultralong-acting analgesia Anesthesiology 101 2004 133 137
39. J.J. Mowat, M.J. Mok, B.A. MacLeod, T.D. Madden Liposomal bupivacaine. Extended duration nerve blockade using large unilamellar vesicles that exhibit a proton gradient Anesthesiology 85 1996 635 643
40. V. Umbrain, M. Alafandy, P. Bourgeosis, J. D'Haese, J.G. Boogaerts, G. Goffinet, F. Camu, F.J. Legros Biodistribution of liposomes after extradural administration in rodents Br J Anaesth 75 1995 311 318
41. L.D. Mayer, L.C.L. Tai, D.S.C. Ko, D. Masin, R.S. Ginsbery, P.R. Cullis, M.B. Bally Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice Cancer Res 49 1989 5922 5930
42. M.S. Wallace, A.M. Yanez, R.J.Y. Ho, D.D. Shen, T.L. Yaksh Antinociception and side effects of liposome-encapsulated alfentanil after spinal delivery in rats Anesth Analg 79 1994 778 786
43. H.Y. Yu, L. Shyh-Dar, P. Sun Kinetic and dynamic studies of liposomal bupivacaine and bupivacaine solution after subcutaneous injection in rats J Pharm Pharmacol 54 2002 1221 1227
44. C.M. Bernards, T.J. Luger, A.B. Malmberg, H.F. Hill, T.L. Yaksh Liposome encapsulation prolongs alfentanil spinal analgesia and alters systemic redistribution in the rat Anesthesiology 77 1992 529 535
45. G.J. Grant, M. Cascio, M.I. Zabowski, L. Langerman, H. Turndorf Intrathecal administration of liposomal morphine in a mouse model Anesth Analg 81 1995 514 518
46. J.G. Boogaerts, N.D. Lafont, S. Carlino, E. Noel, P. Rayal, G. Goffinet, F.J. Legros Biodistribution of liposome-associated bupivacaine after extradural administration in rabbits Br J Anaesth 75 1995 319 325
47. G.J. Grant, K. Vermeulen, L. Langerman, M. Zakowski, H. Turndorf Prolonged analgesia with liposomal bupivacaine in a mouse model Reg Anesth 19 1994 264 269
48. G.J. Grant, B. Piskoun, M. Bansinath Analgesic duration and kinetics of liposomal bupivacaine after subcutaneous injection in mice Clin Exp Pharmacol Physiol 30 2003 966 968
49. J.-M. Malinovsky, D. Benhamou, M. Alafandy, J.-M. Mussini, C. Coussaert, G. Couarraze, M. Pinaud, F.J. Legros Neurotoxicological assessment after intracisternal injection of liposomal bupivacaine in rabbits Anesth Analg 85 1997 1331 1336
50. D.B. Masters, A.J. Domb Liposphere local anesthetic timed-response for perineural site application Pharm Res 15 1998 1038 1045
51. J.G. Boogaerts, N.D. Lafont, A.G. Declercq, H.C. Luo, E.T. Gravet, J.A. Bianchi, F.J. Legros Epidural administration of liposome-associated bupivacaine for the management of postsurgical pain A first study J Clin Anesth 6 1994 315 320
52. N.D. Lafont, J.G. Boogaerts, F.J. Legros Use of liposome-associated bupivacaine for the management of a chronic pain syndrome (correspondence) Anesth Analg 79 1994 818
53. N.D. Lafont, F.J. Legros Use of liposome-associated bupivacaine in a cancer pain syndrome Anaesthesia 51 1996 578 579
54. S.M. Hall The effect of injections of lysophosphatidyl choline into white matter of the adult mouse spinal cord J Cell Sci 10 1972 535 546
55. D.H. Adams, G. Joyce, V.J. Richardson, B.E. Ryman, H. Wisniewski Liposome toxicity in the mouse central nervous system J Neurol Sci 31 1977 173 179
56. J.G. Boogaerts, N. Lafont, M. Donnay, H. Luo, F.J. Legros Motor blockade and absence of local nerve toxicity induced by liposomal bupivacaine injected into the brachial plexus of rabbits Acta Anaesthesiol Belg 46 1995 19 24
57. A.M. Yanez, M. Wallace, R. Ho, D. Shen, T.L. Yaksh Touch-evoked agitation produced by spinally administered phospholipid emulsion and liposomes in rats. Structure-activity relation Anesthesiology 82 1995 1189 1198
58. J.G. Boogaerts, A. Declercq, N. Lafont, H. Benameur, E.M. Akodad, J.C. Dupont, F.J. Legros Toxicity of bupivacaine encapsulated liposomes and injected intravenously comparison with plain solutions Anesth Analg 76 1993 553 555
59. Z.A. Tokes, St Kulcsar, A. Peteri, J.A. Todd Availability of liposome content to the nervous system. Liposomes and the blood-brain barrier Brain Res 188 1980 282 286
60. H.K. Kimelberg, E.G. Mayhew Properties and biological effects of liposomes and their use in pharmacology and toxicology Crit Rev Toxicol 9 1978 25 38
61. F. Reig, M.A. Busquets, I. Haro, F. Rabanal, M.A. Alsina Interaction of opiate molecules with lipid monolayers and liposomes J Pharm Sci 81 1992 546 550
62. C. Hartrick, G. Martin, G. Kantor, G. Manvelian A novel sustained-release formulation of epidural morphine for controlling pain after elective knee arthroplasty Anesthesiology 101 2004 A1138
63. D. Gambling, T. Hughes, G. Martin, G. Manvelian Perioperative, single-injection, sustained-release epidural morphine provides 48-hour pain relief following lower abdominal surgery Anesthesiology 101 2004 A1137
64. B. Carvalho, E.T. Riley, G. Manvelian, D.R. Gambling Management of post-operative pain following cesarean section with epidural sustained-release morphine (SKY0401) Anesthesiology 99 2003 A1165