A model to evaluate the pharmacokinetic and pharmacodynamic variables of extended-release products using in vivo tissue microdialysis in humans: Bupivacaine-loaded microcapsules

Anesthesia and Analgesia

Volumn 97, Issue 1, 2003, Pages 124-131

  Kopacz, Dan J ^a   Bernards, Christopher M ^b   Allen, Hugh W ^a   Landau, Craig ^e   Nandy, Partha ^e   Wu, Danlin ^e   Lacouture, Peter G ^c,d  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Magidom Discovery LLC   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; DEXAMETHASONE;

ANALGESIA; AQUEOUS SOLUTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; DRUG TISSUE LEVEL; DRUG TOLERABILITY; FEMALE; HUMAN; HUMAN EXPERIMENT; INJECTION SITE; MALE; MICROCAPSULE; MICRODIALYSIS; NEUROTOXICITY; NORMAL HUMAN; OPEN STUDY; PHARMACODYNAMICS; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SKIN INDURATION; SUSTAINED RELEASE PREPARATION; SYSTEMIC CIRCULATION;

EID: 0038650795     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000067531.49000.C1     Document Type: Article

References (9)

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