Bupivacaine in microcapsules prolongs analgesia after subcutaneous infiltration in humans: A dose-finding study

Anesthesia and Analgesia

Volumn 99, Issue 3, 2004, Pages 912-918

  Pedersen, Juri L ^a   Lillesø, Jesper ^a   Hammer, Niels A ^a   Werner, Mads U ^a   Holte, Kathrine ^a   Lacouture, Peter G ^b,c,d   Kehlet, Henrik ^a  

^a HVIDOVRE HOSPITAL   (Denmark)

^b Magidom Discovery LLC   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d PURDUE PHARMA L P   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; DEXAMETHASONE; EXTENDED DURATION LOCAL ANESTHETIC AGENT; LOCAL ANESTHETIC AGENT; POLYGLACTIN; UNCLASSIFIED DRUG;

ADULT; ANALGESIC ACTIVITY; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; BLISTER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE CALCULATION; DOUBLE BLIND PROCEDURE; DRUG SAFETY; EDEMA; ERYTHEMA; HEAT; HEMATOMA; HUMAN; HUMAN EXPERIMENT; HYPERESTHESIA; INJECTION SITE; MALE; MECHANICAL STIMULATION; MICROCAPSULE; NORMAL HUMAN; PAIN; PAIN THRESHOLD; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SKIN BURNING SENSATION; SKIN INDURATION; TOUCH;

ADMINISTRATION, CUTANEOUS; ADULT; ANALGESIA; ANESTHETICS, LOCAL; BUPIVACAINE; CAPSULES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; HUMANS; MALE; PAIN THRESHOLD; TIME FACTORS;

EID: 4143126747     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000131971.92180.DF     Document Type: Article

References (11)

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