Glucocorticoids prolong rat sciatic nerve blockade in vivo from bupivacaine microspheres

Anesthesiology

Volumn 85, Issue 5, 1996, Pages 1157-1166

  Castillo, Jenny ^a   Curley, Joanna ^b   Hotz, Joyce ^c   Uezono, Megumi ^d   Tigner, Joseph ^e   Chasin, Mark ^e   Wilder, Robert ^f   Langer, Robert ^b   Berde, Charles ^a,f  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c Medisorb Technologies LP

^d Children's Hospital   (United States)

^e PURDUE PHARMA L P   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Anesthesia, regional; Anesthetics, local: bupivacaine; dexamethasone; Animals: rat; Glucocorticoid; Measurement techniques, microspheres: biodegradable polyester; Nerves, sciatic: blockade; Pharmacology, drug delivery: sustained release

Indexed keywords

BUPIVACAINE; DEXAMETHASONE;

ANIMAL EXPERIMENT; ARTICLE; DRUG POTENCY; DRUG RELEASE; NERVE BLOCK; NONHUMAN; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION; SCIATIC NERVE;

ANESTHETICS, LOCAL; ANIMALS; BUPIVACAINE; CORTODOXONE; DEXAMETHASONE; GLUCOCORTICOIDS; MALE; MICROSPHERES; NERVE BLOCK; NEUTROPHILS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; SCIATIC NERVE; TIME FACTORS;

EID: 0029910188     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199611000-00025     Document Type: Article

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