Exhaled nitric oxide before and after montelukast sodium therapy in school-age children with chronic asthma: A preliminary study

Pediatric Pulmonology

Volumn 28, Issue 6, 1999, Pages 402-407

  Bratton, Donna L ^a   Lanz, Miguel J ^a   Miyazawa, Naomi ^a   White, Carl W ^a   Silkoff, Philip E ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Asthma; Children; Controlled randomized clinical trial; Exhaled nitric oxide; Leukotrienes; Montelukast

Indexed keywords

LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; NITRIC OXIDE; SALBUTAMOL;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BRONCHODILATATION; CHILD; CLINICAL ARTICLE; DISEASE MARKER; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; MALE; PRIORITY JOURNAL; TREATMENT OUTCOME;

ACETATES; ADMINISTRATION, INHALATION; ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ASTHMA; BIOLOGICAL MARKERS; BREATH TESTS; CHILD; CROSS-OVER STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; LEUKOTRIENE ANTAGONISTS; MALE; NITRIC OXIDE; QUINOLINES; REFERENCE VALUES; RESPIRATORY FUNCTION TESTS; TREATMENT OUTCOME;

EID: 0033376698     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0496(199912)28:6<402::AID-PPUL3>3.0.CO;2-V     Document Type: Article

References (34)

1. Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994;343:133-135.
2. Barnes PJ, Liew FY. Nitric oxide and asthmatic inflammation. Immunol Today 1995;16:128-130.
3. Grasemann H, Ioannidis I, de Groot H, Ratjen F. Metabolites of nitric oxide in the lower respiratory tract of children. Eur J Pediatr 1997;156:575-578.
4. Dotsch J, Demirakca S, Terbrack HG, Huls G, Rascher W, Kuhl PG. Airway nitric oxide in asthmatic children and patients with cystic fibrosis. Eur Respir J 1996;9:2537-2540.
5. Dinarevic S, Byrnes CA, Bush A, Shinebourne EA. Measurement of expired nitric oxide levels in children. Pediatr Pulmonol 1996; 22:396-401.
6. Lundberg JO, Nordvall SL, Weitzberg E. Exhaled nitric oxide in paediatric asthma and cystic fibrosis. Arch Dis Child 1996;75: 323-326.
7. Artlich A, Hagenah JU, Jonas S, Ahrens P, Gortner L. Exhaled nitric oxide in childhood asthma. Eur J Pediatr 1996;155:698-701.
8. Nelson BV, Sears S, Woods J, Ling CY, Hunt J, Clapper LM, Gaston B. Expired nitric oxide as a marker for childhood asthma. J Pediatr 1997;130:423-427.
9. Byrnes CA, Dinarevic S, Shinebourne EA, Barnes PJ, Bush A. Exhaled nitric oxide measurements in normal and asthmatic children. Pediatr Pulmonol 1997;24:312-318.
10. Silkoff PE, McClean PA, Slutsky AS, Caramori M, Chapman KR, Gutierrez C, Zamel N. Exhaled nitric oxide and bronchial reactivity during and after inhaled beclomethasone in mild asthma. J Asthma 1998;35:473-479.
11. Lanz MJ, Leung DYM, McCormick DR, Harbeck R, Szefler SJ, White CW. Use of exhaled nitric oxide to monitor ongoing inflammation in children with asthma. Pediatr Pulmonol 1997;24: 305-311.
12. Massaro AF, Gaston B, Kita D, Fanta C, Stamler JS, Drazen JM. Expired nitric oxide levels during treatment of acute asthma. Am J Respir Crit Care Med 1995;152:800-803.
13. Kharitonov SA, Yates DH, Barnes PJ. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1996;153:454-457.
14. Barnes PJ. Nitric oxide and airway disease. Ann Med 1995;27: 389-393.
15. Gaston B, Drazen JM, Loscalzo J, Stamler JS. The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med 1994; 149:538-551.
16. Barnes PJ, Kharitonov SA. Exhaled nitric oxide: a new lung function test. Thorax 1996;51:233-237.
17. Hamid Q, Springall DR, Riveros-Moreno V, Chanez P, Howarth P, Redington A, Bousquet J, Godard P, Holgate S, Polak JM. Induction of nitric oxide synthase in asthma. Lancet 1993;342: 1510-1513.
18. Saleh D, Ernst P, Lim S, Barnes PJ, Giaid A. Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid. FASEB J 1998;12:929-937.
19. 4 in humans. Am Rev Respir Dis 1985;131:368-372.
20. 4 and to methacholine in patients with asthma and normal controls. N Engl J Med 1986; 315:480-484.
21. Knorr B, Matz J, Bernstein JA, Nguyen H, Seidenberg BC, Reiss TF, Becker A. Montelukast for chronic asthma in 6- to 14-year old children. JAMA 1998;279:1181-1186.
22. 4-receptor antagonist, in subjects with bronchial asthma. Am J Respir Crit Care Med 1994; 150:618-623.
23. Reiss TF, Chervinsky P, Dockhorn RJ, Shingo S, Seidenberg B, Edwards TB. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma. Arch Intern Med 1998;158:1213-1220.
24. Israel E, Cohn J, Dube L, Drazen JM. Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. JAMA 1996;275:931-936.
25. Kharitonov SA, Yates DH, Chung KF, Barnes PJ. Changes in the dose of inhaled steroid affect exhaled nitric oxide levels in asthmatic patients. Eur Respir J 1996;9:196-201.
26. Polgar G, Promadhat V. Pulmonary function testing in children: techniques and standards. Philadelphia: W.B. Saunders; 1971. 273 p.
27. Silkoff PE, McClean PA, Slutsky AS, Furlott HG, Hoffstein E, Wakita S, Chapman KR, Szalai JP, Zamel N. Marked flow-dependence of exhaled nitric oxide using a new technique to exclude nasal nitric oxide. Am J Respir Crit Care Med 1997;155: 260-267.
28. Deykin A, Halpern O, Massaro AF, Drazen JM, Israel E. The influence of respiratory maneuvers on exhaled NO. Am J Respir Crit Care Med 1998;157:769-775.
29. Franklin PJ, Taplin R, Stick SM. A community study of exhaled nitric oxide in healthy children. Am J Respir Crit Care Med 1999; 159:69-73.
30. Tamaoki J, Kondo M, Sakai N, Nakata J, Takemura H, Nagai A, Takizawa T, Konno K. Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid. Am J Respir Crit Care Med 1997;155:1235-1240.
31. Robbins RA, Sisson JH, Springall DR. Human lung mononuclear cells induce NOS in murine airway epithelial cells in vitro: role of TNFα and IL-1β. Am J Respir Crit Care Med 1997;155:269-273.
32. Expert Panel. Guidelines for the diagnosis and management of asthma. Report 2. In: National Institutes of Health, National Heart, Lung, and Blood Institute; 1997. 1a-1-1a-3.
33. Frank TL, Adisesh A, Pickering AC, Morrison JFJ, Wright T, Francis H, Fletcher A, Frank PI, Hannaford P. Relationship between exhaled nitric oxide and childhood asthma. Am J Respir Crit Care Med 1998;158:1032-1036.
34. Hogman M, Stromberg S, Schedin U, Frostell C, Hedenstierna G, Gustafsson LE. Nitric oxide from the human respiratory tract efficiently quantified by standardized single breath measurements. Acta Physiol Scand 1997;159:345-346.