Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa

Clinical and Experimental Allergy

Volumn 32, Issue 7, 2002, Pages 1007-1012

  Shirasaki, H ^a,c   Kanaizumi, E ^a   Watanabe, K ^a   Matsui, T ^a   Sato, J ^a   Narita, S ^a   Rautiainen, M ^b   Himi, T ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

CysLT1 receptor; CysLT2 receptor; Nasal mucosa

Indexed keywords

LEUKOTRIENE RECEPTOR; PEPTIDOLEUKOTRIENE RECEPTOR; UNCLASSIFIED DRUG; CYSTEINYL LEUKOTRIENE RECEPTOR 2; LEUKOTRIENE D4; LEUKOTRIENE D4 RECEPTOR; MEMBRANE PROTEIN;

AIRWAY; ARTICLE; CONTROLLED STUDY; EOSINOPHIL; FACIAL BONE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACROPHAGE; NEUTROPHIL; NOSE MUCOSA; NOSE OBSTRUCTION; NOSE SURGERY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TURBINECTOMY; ADOLESCENT; ADULT; CHEMISTRY; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED;

ADOLESCENT; ADULT; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEUKOTRIENE D4; MALE; MIDDLE AGE; NASAL MUCOSA; RECEPTORS, LEUKOTRIENE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPPORT, NON-U.S. GOV'T; HUMANS; MEMBRANE PROTEINS; MIDDLE AGED;

EID: 0035987304     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2002.01425.x     Document Type: Article

References (29)

1. Leukotriene D4 increase nasal blood flow in humans
2. The role of leukotrienes in allergic rhinitis: A review
3. Allergen-induced release of sulphidopeptide leukotrienes (SRS-A) and LTB4 in allergic rhinitis
4. The study of chemical mediators in the patients with allergic rhinitis. 2: Histamine, leukotrienes and kinins in the nasal secretion during dual phase response
5. The leukotriene D4-receptor antagonist, ICI 204, 219, relieves symptoms of acute seasonal allergic rhinitis
6. Comparative role of peptide leukotrienes and histamine in the development of nasal mucosal swelling in nasal allergy
7. Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: A randomized, placebo-controlled clinical trial
8. Characterization of the human cysteinyl leukotriene CysLT1 receptor
9. Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor
10. Characterization of the human cysteinyl leukotriene 2 receptor
11. The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT2 receptor
12. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
13. Effects of leukotriene C4 and D4, histamine and bradykinin on cytosolic calcium concentrations and adhesiveness of endothelial cells and neutrophils
14. Selectivity of recombinant human leukotriene D4, leukotriene B4, and lipoxin A4 receptors with aspirin-triggered 15-epi-LXA4 and regulation of vascular and inflammatory responses
15. Response to anti-human IgE in human pulmonary arteries: Regulation by the endothelium
16. Effect of leukotriene C4 and D4 on human isolated saphenous veins
17. Role of substance P in the vascular response of nasal mucosa in nasal allergy
18. Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes
19. Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: Significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils
20. Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by mast cells
21. Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism
22. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma
23. Effect of zafirlukast (Accolate) on cellular mediators of inflammation
24. Pranlukast protects leukotriene C4-and D4-induced epithelial cell impairment of the nasal mucosa in vitro
25. Effect of leukotriene D4 on ciliary activity in human, guinea-pig and rat respiratory mucosa
26. SRS-A leukotriene decrease the activity of human respiratory cilia
27. Histamine and leukotriene C4 effects on in vitro ciliary beat frequency of human upper respiratory cilia
28. M 1/MUC5AC mucin released by human airways in vitro
29. Effects of leukotrienes C4 and D4 on glycoprotein and lysozyme secretion by human bronchial mucosa