Effect of zafirlukast on methacholine and ultrasonically nebulized distilled water challenge in patients with mild asthma

Respiration

Volumn 70, Issue 3, 2003, Pages 249-253

  Carratu P ^a   Morelli, N ^b   Freire, A X ^a   Pugazhenthi, M ^a   Guerra, S ^b   Umberger, R ^a   Allegra, L ^b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Bonchoconstriction; Bronchial asthma; Cysteinyl leukotrienes; Methacholine; Ultrasonically nebulized distilled water; Zafirlukast

Indexed keywords

LEUKOTRIENE RECEPTOR BLOCKING AGENT; METHACHOLINE; PEPTIDOLEUKOTRIENE; ZAFIRLUKAST;

ADULT; ARTICLE; ASTHMA; BRONCHOSPASM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION TEST; MALE; PREVENTIVE MEDICINE; PRIORITY JOURNAL; PROVOCATION TEST; RANDOMIZATION; SINGLE BLIND PROCEDURE;

ADULT; ASTHMA; BRONCHIAL PROVOCATION TESTS; BRONCHOCONSTRICTION; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LEUKOTRIENE ANTAGONISTS; MALE; TOSYL COMPOUNDS;

EID: 0041571549     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000072005     Document Type: Article

References (28)

1. Samuelsson B, Dahlen SE, Lindgren JA, et al: Leukotrienes and lipoxins: Structures, biosynthesis and biological effects. Science 1987;237:1171-1176.
2. Lewis RA, Austen KF, Soberman RJ: Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N Engl J Med 1990;323:645-655.
3. 4 enhance histamine responsiveness in asthmatic airways. Am Rev Respir Dis 1991;144:1053-1057.
4. 4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfido-peptide leukotriene receptors. Proc Natl Acad Sci USA 1984;81:4922-4925.
5. 4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis 1990;142:112-119.
6. Holgate ST, Bradding P, Sampson AP: Leukotriene antagonists and synthesis inhibitors: New directions in asthma therapy. J Allergy Clin Immunol 1996;98:1-13.
7. 4-receptor antagonist. N Engl J Med 1990;323:1736-1739.
8. Israel E, Dermarkarian R, Rosenberg M, et al: The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N Engl J Med 1990;323:1740-1744.
9. Taylor IK, O'Shaughnessy KM, Fuller RW, et al: Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects. Lancet 1991;337:690-694.
10. Christie PE, Smith CM, Lee TH: The potent and selective sulfidopeptide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma. Am Rev Respir Dis 1991;144:957-958.
11. Yoshida S, Sakamoto H, Ishizaki Y, et al: Efficacy of leukotriene receptor antagonist in bronchial hyperresponsiveness and hypersensitivity to analgesic in aspirin- intolerant asthma. Clin Exp Allergy 2000;30:64-70.
12. American Thoracic Society: Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis 1987;136:225-244.
13. Linn WS, Solomon JC, Gong H Jr et al: Standardization of multiple spirometers at widely separated times and places. Am J Respir Crit Care Med 1996;153:1309-1313.
14. Morris JF, Koski A, Johnson LC: Spirometric standards for healthy nonsmoking adults. Am Rev Respir Dis 1971;103:57-67.
15. Sterk PJ, Fabbri LM, Quanier H, et al: Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:53-83.
16. Salvi SS, Krishna MT, Sampson AP, et al: The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma. Chest 2001;119:1533-1546.
17. Obase Y, Shimoda T, Tomari S, et al: Efficacy and safety of long-term treatment of asthmatic patients with pranlukast, a cysteinyl-leukotriene-receptor antagonist: Four-year follow-up study. Ann Allergy Asthma Immunol 2001;87: 43-47.
18. Knorr B, Matz J, Bernstein JA, et al: Montelukast for chronic asthma in 6- to 14-year-old children: A randomized, double-blind trial. Pediatric montelukast study group. JAMA 1998; 279:1181-1186.
19. Israel E, Fischer AR, Rosenberg MA, et al: The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis 1993;148:1447-1451.
20. Dahlen B, Kumlin M, Margolskee DJ, et al: The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin-sensitive asthmatics. Eur Respir J 1993;6:1018-1026.
21. 4 receptor antagonist. Am Rev Respir Dis 1992;145:746-749.
22. Leff JA, Busse WW, Pearlman D, et al: Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. N Engl J Med 1998;339:147-152.
23. Dessanges JF, Prefaut C, Taytard A, et al: The effect of zafirlukast on repetitive exercise-induced bronchoconstriction: The possible role of leukotrienes in exercise-induced refractoriness. J Allergy Clin Immunol 1999;104:1155-1161.
24. Meltzer SS, Hasday JD, Cohn J, et al: Inhibition of exercise-induced bronchospasm by zileuton: A 5-lipoxygenase inhibitor. Am J Respir Crit Care Med 1996;153:931-935.
25. Dahlen B: Treatment of aspirin-intolerant asthma with antileukotrienes. Am J Respir Crit Care Med 2000;161:S137-S141.
26. Tan RA, Spector SL: Exercise-induced asthma: Diagnosis and management. Ann Allergy Asthma Immunol 2002;89:226-235.
27. Coreno A, Skowronsky M, Kotaru C, McFadden ER Jr: Comparative effects of long-acting β2-agonists, leukotriene receptor antagonists, and a 5-lipoxygenase inhibitor on exercise-induced asthma J Allergy Clin Immunol 2000;106:500-506.
28. Cockcroft DW: How best to measure airway responsiveness. Am J Respir Crit Care Med 2001;163:1514-1515.