-
1
-
-
0037785185
-
Cardiovascular disease
-
E.G. Nabel Cardiovascular disease N. Engl. J. Med. 349 2003 60 72
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 60-72
-
-
Nabel, E.G.1
-
2
-
-
18844460845
-
-
National Heart, Lung and Blood Institute
-
National Heart, Lung and Blood Institute (2003) NHLBI Morbidity and Mortality Chartbook 2002. National Heart, Lung and Blood Institute (http://www.americanheart.org)
-
(2003)
NHLBI Morbidity and Mortality Chartbook 2002
-
-
-
3
-
-
0036397852
-
Virus-based gene delivery systems
-
C. Mah Virus-based gene delivery systems Clin. Pharmacokinet. 41 2002 901 911
-
(2002)
Clin. Pharmacokinet.
, vol.41
, pp. 901-911
-
-
Mah, C.1
-
4
-
-
0036954247
-
Gene therapy progress and prospects: Non-viral vectors
-
T. Niidome, and L. Huang Gene therapy progress and prospects: non-viral vectors Gene Ther. 9 2002 1647 1652
-
(2002)
Gene Ther.
, vol.9
, pp. 1647-1652
-
-
Niidome, T.1
Huang, L.2
-
5
-
-
1842559592
-
Gene and cell-based therapies for heart disease
-
L.G. Melo Gene and cell-based therapies for heart disease FASEB J. 18 2004 648 663
-
(2004)
FASEB J.
, vol.18
, pp. 648-663
-
-
Melo, L.G.1
-
6
-
-
0030855813
-
In vivo transfection of cis element 'decoy' against nuclear factor κb binding sites prevents myocardial infarction
-
R. Morishita In vivo transfection of cis element 'decoy' against nuclear factor κB binding sites prevents myocardial infarction Nat. Med. 3 1997 894 899
-
(1997)
Nat. Med.
, vol.3
, pp. 894-899
-
-
Morishita, R.1
-
7
-
-
2542445544
-
Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: Reasons for cautious optimism
-
L.G. Melo Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: reasons for cautious optimism Circulation 109 2004 2386 2393
-
(2004)
Circulation
, vol.109
, pp. 2386-2393
-
-
Melo, L.G.1
-
8
-
-
0032853699
-
Immune responses to adenovirus and adeno associated virus in humans
-
N. Chirmule Immune responses to adenovirus and adeno associated virus in humans Gene Ther. 6 1999 1574 1583
-
(1999)
Gene Ther.
, vol.6
, pp. 1574-1583
-
-
Chirmule, N.1
-
9
-
-
4344573909
-
Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury
-
A.S. Pachori Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury Proc. Natl. Acad. Sci. U. S. A. 101 2004 12282 12287
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 12282-12287
-
-
Pachori, A.S.1
-
10
-
-
0036726577
-
Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy
-
S.A. Nicklin, and A.H. Baker Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy Curr. Gene Ther. 2 2002 273 293
-
(2002)
Curr. Gene Ther.
, vol.2
, pp. 273-293
-
-
Nicklin, S.A.1
Baker, A.H.2
-
11
-
-
5344271164
-
Endothelium targeted gene and cell-based therapies for cardiovascular disease
-
L.G. Melo Endothelium targeted gene and cell-based therapies for cardiovascular disease Arterioscler. Thromb. Vasc. Biol. 24 2004 1761 1774
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 1761-1774
-
-
Melo, L.G.1
-
12
-
-
0030729072
-
Optimal techniques for arterial gene transfer
-
L.J. Feldman, and G. Steg Optimal techniques for arterial gene transfer Cardiovasc. Res. 35 1997 391 404
-
(1997)
Cardiovasc. Res.
, vol.35
, pp. 391-404
-
-
Feldman, L.J.1
Steg, G.2
-
13
-
-
0036211385
-
A tissue-engineered stent for cell-based vascular gene transfer
-
C.J. Panetta A tissue-engineered stent for cell-based vascular gene transfer Hum. Gene Ther. 13 2002 433 441
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 433-441
-
-
Panetta, C.J.1
-
14
-
-
3042828271
-
Local gene transfer of phVEGF-2 plasmid by gene eluting stents: An alternative strategy for inhibition of restenosis
-
D.H. Walter Local gene transfer of phVEGF-2 plasmid by gene eluting stents: an alternative strategy for inhibition of restenosis Circulation 110 2004 36 45
-
(2004)
Circulation
, vol.110
, pp. 36-45
-
-
Walter, D.H.1
-
15
-
-
16244379892
-
Stent-based delivery of tissue inhibitor of metalloproteinase-3 adenovirus inhibits neointimal formation in porcine coronary arteries
-
10.1161/01.ATV.0000157582.33180.a9
-
Johnson, T.W. et al. (2005). Stent-based delivery of tissue inhibitor of metalloproteinase-3 adenovirus inhibits neointimal formation in porcine coronary arteries. Arterioscler. Thromb. Vasc. Biol. 10.1161/01.ATV.0000157582.33180.a9 (www.atvb.ahajournals.org)
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
-
-
Johnson, T.W.1
-
16
-
-
0036204767
-
Gene delivery to pig coronary arteries from stents carrying antibody-tethered adenovirus
-
B.D. Klugherz Gene delivery to pig coronary arteries from stents carrying antibody-tethered adenovirus Hum. Gene Ther. 13 2002 443 454
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 443-454
-
-
Klugherz, B.D.1
-
17
-
-
5444273589
-
Current status of catheter- and stent-based gene therapy
-
F. Sharif Current status of catheter- and stent-based gene therapy Cardiovasc. Res. 64 2004 208 216
-
(2004)
Cardiovasc. Res.
, vol.64
, pp. 208-216
-
-
Sharif, F.1
-
18
-
-
0037049981
-
Myocardial gene therapy
-
J.M. Isner Myocardial gene therapy Nature 415 2002 234 239
-
(2002)
Nature
, vol.415
, pp. 234-239
-
-
Isner, J.M.1
-
19
-
-
0036118514
-
Catheter-based transendocardial myocardial gene transfer
-
C. Sylvein Catheter-based transendocardial myocardial gene transfer J. Interv. Cardiol. 15 2002 7 13
-
(2002)
J. Interv. Cardiol.
, vol.15
, pp. 7-13
-
-
Sylvein, C.1
-
20
-
-
0033767577
-
Therapeutic applications of transcription factor decoy oligonucleotides
-
M.J. Mann, and V.J. Dzau Therapeutic applications of transcription factor decoy oligonucleotides J. Clin. Invest. 106 2000 1071 1075
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1071-1075
-
-
Mann, M.J.1
Dzau, V.J.2
-
21
-
-
0034798245
-
The experimental use of antisense oligonucleotides: A guide for the perplexed
-
C.A. Stein The experimental use of antisense oligonucleotides: a guide for the perplexed J. Clin. Invest. 108 2001 641 644
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 641-644
-
-
Stein, C.A.1
-
22
-
-
0037062949
-
The chemical repertoire of natural ribozymes
-
J.A. Doudna, and T.R. Cech The chemical repertoire of natural ribozymes Nature 418 2002 222 228
-
(2002)
Nature
, vol.418
, pp. 222-228
-
-
Doudna, J.A.1
Cech, T.R.2
-
23
-
-
0037062951
-
RNA interference
-
G.J. Hannon RNA interference Nature 418 2002 244 251
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
24
-
-
0033791140
-
Developing aptamers into therapeutics
-
R.R. White Developing aptamers into therapeutics J. Clin. Invest. 106 2000 929 934
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 929-934
-
-
White, R.R.1
-
25
-
-
0030793748
-
Prolonged reduction of high blood pressure with human nitric oxide synthase delivery
-
K.F. Lin Prolonged reduction of high blood pressure with human nitric oxide synthase delivery Hypertension 30 1997 307 313
-
(1997)
Hypertension
, vol.30
, pp. 307-313
-
-
Lin, K.F.1
-
26
-
-
0032126984
-
Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy and renal injury in salt-sensitive rats
-
K.F. Lin Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy and renal injury in salt-sensitive rats Hum. Gene Ther. 9 1998 1429 1438
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 1429-1438
-
-
Lin, K.F.1
-
27
-
-
0033670493
-
Adrenomedullin gene delivery attenuates hypertension, cardiac remodeling and renal injury in deoxycorticosterone acetate salt hypertensive rats
-
E. Dobrzynski Adrenomedullin gene delivery attenuates hypertension, cardiac remodeling and renal injury in deoxycorticosterone acetate salt hypertensive rats Hypertension 36 2000 995 1001
-
(2000)
Hypertension
, vol.36
, pp. 995-1001
-
-
Dobrzynski, E.1
-
28
-
-
0033958237
-
Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion
-
H. Yoshida Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion Hypertension 35 2000 25 31
-
(2000)
Hypertension
, vol.35
, pp. 25-31
-
-
Yoshida, H.1
-
29
-
-
0033370798
-
Intravenous angiotensinogen antisense in AAV-based vector decreases hypertension
-
X. Tang Intravenous angiotensinogen antisense in AAV-based vector decreases hypertension Am. J. Physiol. 277 1999 H2392 H2399
-
(1999)
Am. J. Physiol.
, vol.277
-
-
Tang, X.1
-
30
-
-
0033214337
-
Sustained inhibition of angiotensin I converting enzyme (ACE) expression and long-term antihypertensive action by virally mediated delivery of ACE antisense cDNA
-
H. Wang Sustained inhibition of angiotensin I converting enzyme (ACE) expression and long-term antihypertensive action by virally mediated delivery of ACE antisense cDNA Circ. Res. 85 1999 614 622
-
(1999)
Circ. Res.
, vol.85
, pp. 614-622
-
-
Wang, H.1
-
31
-
-
0032887928
-
Reversal of hypertension by angiotensin II type I receptor antisense gene therapy in the adult SHR rat
-
M.J. Katovich Reversal of hypertension by angiotensin II type I receptor antisense gene therapy in the adult SHR rat Am. J. Physiol. 277 1999 H1260 H1264
-
(1999)
Am. J. Physiol.
, vol.277
-
-
Katovich, M.J.1
-
32
-
-
0033954747
-
New β-blocker: Prolonged reduction in high blood pressure with β1 antisense oligodeoxynucleotides
-
Y.C. Zhang New β-blocker: prolonged reduction in high blood pressure with β1 antisense oligodeoxynucleotides Hypertension 35 2000 219 224
-
(2000)
Hypertension
, vol.35
, pp. 219-224
-
-
Zhang, Y.C.1
-
33
-
-
0032493266
-
Cell cycle progression. New therapeutic target for vascular proliferative disease
-
R.D. Braun-Dullaeus Cell cycle progression. New therapeutic target for vascular proliferative disease Circulation 98 1998 82 89
-
(1998)
Circulation
, vol.98
, pp. 82-89
-
-
Braun-Dullaeus, R.D.1
-
34
-
-
0037040150
-
Early loss of thrombomodulin expresson impairs vein graft thromboresistance: Implications for vein graft resistance
-
A.Y. Kim Early loss of thrombomodulin expresson impairs vein graft thromboresistance: implications for vein graft resistance Circ. Res. 90 2002 205 212
-
(2002)
Circ. Res.
, vol.90
, pp. 205-212
-
-
Kim, A.Y.1
-
35
-
-
0034711777
-
Thromboresistance of balloon-injured porcine carotid arteries after local gene transfer of human tissue factor pathway inhibitor
-
P. Zoldhelyi Thromboresistance of balloon-injured porcine carotid arteries after local gene transfer of human tissue factor pathway inhibitor Circulation 101 2000 289 295
-
(2000)
Circulation
, vol.101
, pp. 289-295
-
-
Zoldhelyi, P.1
-
36
-
-
0034603834
-
Thrombi in acute coronary syndromes. Revised and revisited
-
K.P. Rentrop Thrombi in acute coronary syndromes. Revised and revisited Circulation 101 2000 1619 1626
-
(2000)
Circulation
, vol.101
, pp. 1619-1626
-
-
Rentrop, K.P.1
-
38
-
-
0032706442
-
Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-1 in mice
-
R.K. Tangirala Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-1 in mice Circulation 100 1999 1816 1822
-
(1999)
Circulation
, vol.100
, pp. 1816-1822
-
-
Tangirala, R.K.1
-
39
-
-
0037137305
-
Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice
-
S. Inoue Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice Circulation 106 2002 2700 2706
-
(2002)
Circulation
, vol.106
, pp. 2700-2706
-
-
Inoue, S.1
-
40
-
-
0035810911
-
Therapeutic potential of nitric oxide synthase gene manipulation
-
H.E. von der Leyen, and V.J. Dzau Therapeutic potential of nitric oxide synthase gene manipulation Circulation 103 2001 2760 2765
-
(2001)
Circulation
, vol.103
, pp. 2760-2765
-
-
Von Der Leyen, H.E.1
Dzau, V.J.2
-
41
-
-
0036065962
-
Vasoprotection by nitric oxide: Mechanisms and therapeutic potential
-
M.T. Gewaltig, and G. Kojda Vasoprotection by nitric oxide: mechanisms and therapeutic potential Cardiovasc. Res. 55 2002 250 260
-
(2002)
Cardiovasc. Res.
, vol.55
, pp. 250-260
-
-
Gewaltig, M.T.1
Kojda, G.2
-
42
-
-
0033564035
-
Nitric oxide synthase gene therapy rapidly reduces molecule expression and inflammatory cell infiltration in carotid artery of cholesterol-fed rabbits
-
H. Qian Nitric oxide synthase gene therapy rapidly reduces molecule expression and inflammatory cell infiltration in carotid artery of cholesterol-fed rabbits Circulation 99 1999 2979 2982
-
(1999)
Circulation
, vol.99
, pp. 2979-2982
-
-
Qian, H.1
-
43
-
-
0035949615
-
Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice
-
S.H. Juan Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice Circulation 104 2001 1519 1525
-
(2001)
Circulation
, vol.104
, pp. 1519-1525
-
-
Juan, S.H.1
-
44
-
-
0034834461
-
Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in the absence but not in the presence of atherosclerotic plaque
-
M. Zanetti Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in the absence but not in the presence of atherosclerotic plaque Hum. Gene Ther. 12 2001 1407 1416
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 1407-1416
-
-
Zanetti, M.1
-
45
-
-
0028793489
-
A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia
-
M. Grossman A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia Nat. Med. 1 1995 1148 1154
-
(1995)
Nat. Med.
, vol.1
, pp. 1148-1154
-
-
Grossman, M.1
-
46
-
-
0036851826
-
Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies
-
V.J. Dzau Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies Nat. Med. 8 2002 1249 1256
-
(2002)
Nat. Med.
, vol.8
, pp. 1249-1256
-
-
Dzau, V.J.1
-
47
-
-
0028798793
-
Gene therapy inhibiting neointimal vascular lesion: In vivo transfer of endothelial cell nitric oxide synthase gene
-
H.E. Von der Leyen Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene Proc. Natl. Acad. Sci. U. S. A. 92 1995 1137 1141
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 1137-1141
-
-
Von Der Leyen, H.E.1
-
48
-
-
0029753229
-
Vascular gene transfer of the human inducible nitric oxide synthase: Characterization of activity and effects of myointimal hyperplasia
-
E. Tzeng Vascular gene transfer of the human inducible nitric oxide synthase: characterization of activity and effects of myointimal hyperplasia Mol. Med. 2 1996 211 215
-
(1996)
Mol. Med.
, vol.2
, pp. 211-215
-
-
Tzeng, E.1
-
49
-
-
0027323303
-
Single intraluminal delivery of antisense cdc2 kinase and proliferating cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia
-
R. Morishita Single intraluminal delivery of antisense cdc2 kinase and proliferating cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia Proc. Natl. Acad. Sci. U. S. A. 90 1993 8474 8478
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 8474-8478
-
-
Morishita, R.1
-
50
-
-
0029019576
-
Genetic engineering of vein grafts resistant to atherosclerosis
-
M.J. Mann Genetic engineering of vein grafts resistant to atherosclerosis Proc. Natl. Acad. Sci. U. S. A. 92 1995 4502 4506
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 4502-4506
-
-
Mann, M.J.1
-
51
-
-
0030893643
-
Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts
-
M.J. Mann Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts J. Clin. Invest. 99 1997 1295 1301
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1295-1301
-
-
Mann, M.J.1
-
52
-
-
0029031549
-
A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo
-
R. Morishita A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo Proc. Natl. Acad. Sci. U. S. A. 92 1995 5855 5859
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 5855-5859
-
-
Morishita, R.1
-
53
-
-
0037022253
-
Gene therapy strategy for long term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene
-
L.G. Melo Gene therapy strategy for long term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene Circulation 105 2002 602 607
-
(2002)
Circulation
, vol.105
, pp. 602-607
-
-
Melo, L.G.1
-
54
-
-
2542461020
-
Preemptive gene therapy by AAV-mediated delivery of heme oxygenase-1 results in long-term normalization of left ventricular function and chamber dimensions
-
L.G. Melo Preemptive gene therapy by AAV-mediated delivery of heme oxygenase-1 results in long-term normalization of left ventricular function and chamber dimensions Circulation 108 Suppl. IV 2003 IV 144
-
(2003)
Circulation
, vol.108
, Issue.4 SUPPL.
, pp. 144
-
-
Melo, L.G.1
-
55
-
-
3142735150
-
Pre-emptive gene therapy using recombinant adeno-associated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury, improves ventricular function and prolongs survival
-
R.S. Agrawal Pre-emptive gene therapy using recombinant adeno-associated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury, improves ventricular function and prolongs survival Gene Ther. 11 2004 962 969
-
(2004)
Gene Ther.
, vol.11
, pp. 962-969
-
-
Agrawal, R.S.1
-
56
-
-
0344542713
-
Recombinant adenovirus-mediated cardiac gene transfer of superoxide dismutase and catalase attenuates postischemic contractile dysfunction
-
Y.Z. Woo Recombinant adenovirus-mediated cardiac gene transfer of superoxide dismutase and catalase attenuates postischemic contractile dysfunction Circulation 98 Suppl. 1998 II255 II260
-
(1998)
Circulation
, vol.98
, Issue.SUPPL.
-
-
Woo, Y.Z.1
-
57
-
-
0034322119
-
Blocking free radical production via adenoviral gene transfer decreases cardiac ischemia-reperfusion injury
-
H.L. Zhu Blocking free radical production via adenoviral gene transfer decreases cardiac ischemia-reperfusion injury Mol. Ther. 2 2000 470 475
-
(2000)
Mol. Ther.
, vol.2
, pp. 470-475
-
-
Zhu, H.L.1
-
58
-
-
0030218917
-
Transgenic mice overespressing glutathione peroxidase are resistant to myocardial reperfusion injury
-
T. Yoshida Transgenic mice overespressing glutathione peroxidase are resistant to myocardial reperfusion injury J. Mol. Cell. Cardiol. 28 1996 1759 1767
-
(1996)
J. Mol. Cell. Cardiol.
, vol.28
, pp. 1759-1767
-
-
Yoshida, T.1
-
59
-
-
0030898927
-
In vivo gene transfer of heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat
-
K. Suzuki In vivo gene transfer of heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat J. Clin. Invest. 99 1997 1645 1650
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1645-1650
-
-
Suzuki, K.1
-
60
-
-
0037167707
-
Viral gene transfer of the antiapoptotic factor Bcl-2 protects against chronic ischemic heart failure
-
S. Chatterjee Viral gene transfer of the antiapoptotic factor Bcl-2 protects against chronic ischemic heart failure Circulation 106 Suppl. 2002 I212 I217
-
(2002)
Circulation
, vol.106
, Issue.SUPPL.
-
-
Chatterjee, S.1
-
61
-
-
0035902451
-
Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
-
T. Matsui Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo Circulation 104 2001 330 335
-
(2001)
Circulation
, vol.104
, pp. 330-335
-
-
Matsui, T.1
-
62
-
-
0031469388
-
Intracoronary adenovirus-mediated transfer of immunosuppressive cytokine genes prolongs allograft survival
-
R. Brauner Intracoronary adenovirus-mediated transfer of immunosuppressive cytokine genes prolongs allograft survival J. Thorac. Cardiovasc. Surg. 114 1997 923 933
-
(1997)
J. Thorac. Cardiovasc. Surg.
, vol.114
, pp. 923-933
-
-
Brauner, R.1
-
63
-
-
0031940012
-
Biological bypass with the use of adenovirus-mediated transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart
-
C.A. Mack Biological bypass with the use of adenovirus-mediated transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart J. Thorac. Cardiovasc. Surg. 115 1998 168 177
-
(1998)
J. Thorac. Cardiovasc. Surg.
, vol.115
, pp. 168-177
-
-
MacK, C.A.1
-
64
-
-
0033520056
-
121 cDNA to individuals with clinically significant severe coronary artery disease
-
121 cDNA to individuals with clinically significant severe coronary artery disease Circulation 100 1999 468 474
-
(1999)
Circulation
, vol.100
, pp. 468-474
-
-
Rosengart, T.K.1
-
65
-
-
0032698604
-
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease
-
J.F. Symes Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease Ann. Thorac. Surg. 68 1999 830 837
-
(1999)
Ann. Thorac. Surg.
, vol.68
, pp. 830-837
-
-
Symes, J.F.1
-
66
-
-
0029877965
-
Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in ischemic region of the heart
-
F.J. Giordano Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in ischemic region of the heart Nat. Med. 2 1996 534 539
-
(1996)
Nat. Med.
, vol.2
, pp. 534-539
-
-
Giordano, F.J.1
-
67
-
-
0032578961
-
165 as sole therapy for myocardial ischemia
-
165 as sole therapy for myocardial ischemia Circulation 98 1998 2800 2804
-
(1998)
Circulation
, vol.98
, pp. 2800-2804
-
-
Losordo, D.W.1
-
68
-
-
6644223710
-
Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia
-
P.R. Vale Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia Circulation 103 2001 2138 2143
-
(2001)
Circulation
, vol.103
, pp. 2138-2143
-
-
Vale, P.R.1
-
69
-
-
0037197740
-
Phase 1/2 placebo-controlled, double-blind, dose escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia
-
D.W. Losordo Phase 1/2 placebo-controlled, double-blind, dose escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia Circulation 105 2002 2012 2018
-
(2002)
Circulation
, vol.105
, pp. 2012-2018
-
-
Losordo, D.W.1
-
70
-
-
0037383667
-
Gene transfer of hepatocyte growth factor improves angiogenesis and function of chronic ischemic myocardium in canine heart
-
I. Ahmet Gene transfer of hepatocyte growth factor improves angiogenesis and function of chronic ischemic myocardium in canine heart Ann. Thorac. Surg. 75 2003 1283 1287
-
(2003)
Ann. Thorac. Surg.
, vol.75
, pp. 1283-1287
-
-
Ahmet, I.1
-
71
-
-
0033039832
-
Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart
-
H. Ueda Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart Ann. Thorac. Surg. 67 1999 1726 1731
-
(1999)
Ann. Thorac. Surg.
, vol.67
, pp. 1726-1731
-
-
Ueda, H.1
-
72
-
-
0037841974
-
Post-infarction treatment with and adenoviral vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice
-
Y. Li Post-infarction treatment with and adenoviral vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice Circulation 107 2003 2499 2506
-
(2003)
Circulation
, vol.107
, pp. 2499-2506
-
-
Li, Y.1
-
73
-
-
0036084754
-
Cardiac overexpression of A1-adenosine receptor protects intact mice against myocardial infarction
-
Z. Yang Cardiac overexpression of A1-adenosine receptor protects intact mice against myocardial infarction Am. J. Physiol. 282 2002 H949 H955
-
(2002)
Am. J. Physiol.
, vol.282
-
-
Yang, Z.1
-
74
-
-
0034737825
-
Prospects for gene therapy for heart failure
-
R.J. Hajjar Prospects for gene therapy for heart failure Circ. Res. 86 2000 616 621
-
(2000)
Circ. Res.
, vol.86
, pp. 616-621
-
-
Hajjar, R.J.1
-
75
-
-
17344389993
-
2-adrenergic receptor in the heart, prospects for molecular ventricular assistance
-
2-adrenergic receptor in the heart, prospects for molecular ventricular assistance Circulation 101 2000 408 414
-
(2000)
Circulation
, vol.101
, pp. 408-414
-
-
Shah, A.S.1
-
76
-
-
0037155776
-
Transcriptional regulation of vertebrate cardiac morphogenesis
-
B.G. Bruneau Transcriptional regulation of vertebrate cardiac morphogenesis Circ. Res. 90 2002 509 519
-
(2002)
Circ. Res.
, vol.90
, pp. 509-519
-
-
Bruneau, B.G.1
-
77
-
-
0037154148
-
Rescue of hereditary form of dilated cardiomyopathy by rAAV-mediated somatic gene therapy, Amelioration of morphological findings, sarcolemmal permeability, cardiac performance and the prognosis of TO-2 hamsters
-
T. Kawada Rescue of hereditary form of dilated cardiomyopathy by rAAV-mediated somatic gene therapy, Amelioration of morphological findings, sarcolemmal permeability, cardiac performance and the prognosis of TO-2 hamsters Proc. Natl. Acad. Sci. U. S. A. 99 2002 901 906
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 901-906
-
-
Kawada, T.1
-
78
-
-
0034530074
-
Focal modification of electrical conduction in the heart by viral gene transfer
-
J.K. Donahue Focal modification of electrical conduction in the heart by viral gene transfer Nat. Med. 6 2000 1395 1398
-
(2000)
Nat. Med.
, vol.6
, pp. 1395-1398
-
-
Donahue, J.K.1
-
79
-
-
0033559392
-
Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes
-
H.B. Nuss Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes J. Clin. Invest. 103 1999 889 896
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 889-896
-
-
Nuss, H.B.1
-
80
-
-
0042917782
-
Gene transfer of hepatocyte growth factor attenuates postinfarction heart failure
-
V. Jayasankar Gene transfer of hepatocyte growth factor attenuates postinfarction heart failure Circulation 108 Suppl. 1 2003 II230 II236
-
(2003)
Circulation
, vol.108
, Issue.1 SUPPL.
-
-
Jayasankar, V.1
-
81
-
-
0036311037
-
Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy
-
Y. Taniyama Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy Hypertension 40 2002 47 53
-
(2002)
Hypertension
, vol.40
, pp. 47-53
-
-
Taniyama, Y.1
-
82
-
-
9244261579
-
Adeno-associated viral vector delivers cardiac specific and hypoxia inducible VEGF expression in ischemic mouse hearts
-
H. Su Adeno-associated viral vector delivers cardiac specific and hypoxia inducible VEGF expression in ischemic mouse hearts Proc. Natl. Acad. Sci. U. S. A. 101 2004 16280 16285
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 16280-16285
-
-
Su, H.1
-
83
-
-
0036912846
-
Induction of angiogenesis in a mouse model using engineered transcription factors
-
E.J. Rebar Induction of angiogenesis in a mouse model using engineered transcription factors Nat. Med. 8 2002 1427 1432
-
(2002)
Nat. Med.
, vol.8
, pp. 1427-1432
-
-
Rebar, E.J.1
-
84
-
-
0037968240
-
Gene transfer as a tool to induce therapeutic vascular growth
-
S.Y. Herttuala, and K. Alitalo Gene transfer as a tool to induce therapeutic vascular growth Nat. Med. 9 2003 694 700
-
(2003)
Nat. Med.
, vol.9
, pp. 694-700
-
-
Herttuala, S.Y.1
Alitalo, K.2
-
85
-
-
0037050022
-
The failing heart
-
J.A. Towbin, and N.E. Bowles The failing heart Nature 415 2002 227 233
-
(2002)
Nature
, vol.415
, pp. 227-233
-
-
Towbin, J.A.1
Bowles, N.E.2
-
86
-
-
0032745831
-
2-adrenergic receptor gene delivery
-
2-adrenergic receptor gene delivery J. Clin. Invest. 104 1999 21 29
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 21-29
-
-
Maurice, J.P.1
-
87
-
-
0030726783
-
Restoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer
-
S.A. Akhter Restoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer Proc. Natl. Acad. Sci. U. S. A. 94 1997 12100 12105
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 12100-12105
-
-
Akhter, S.A.1
-
88
-
-
0035908945
-
2+-ATPase in a rat model of heart failure
-
2+-ATPase in a rat model of heart failure Circulation 104 2001 1424 1429
-
(2001)
Circulation
, vol.104
, pp. 1424-1429
-
-
Del Monte, F.1
-
89
-
-
0033534053
-
Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a
-
F. Del Monte Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a Circulation 100 1999 2308 2311
-
(1999)
Circulation
, vol.100
, pp. 2308-2311
-
-
Del Monte, F.1
-
90
-
-
0035254550
-
Adenovirus gene transfer of SERCA in heart failure. A promising therapeutic approach?
-
A. Baartscheer Adenovirus gene transfer of SERCA in heart failure. A promising therapeutic approach? Cardiovasc. Res. 49 2001 249 252
-
(2001)
Cardiovasc. Res.
, vol.49
, pp. 249-252
-
-
Baartscheer, A.1
-
91
-
-
0036087310
-
Inherited sodium channelopathies: Models for acquired arrhythmias?
-
J.R. Balser Inherited sodium channelopathies: models for acquired arrhythmias? Am. J. Physiol. Heart Circ. Physiol. 282 2002 H1175 H1180
-
(2002)
Am. J. Physiol. Heart Circ. Physiol.
, vol.282
-
-
Balser, J.R.1
-
92
-
-
8544271664
-
Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation
-
A. Bauer Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation Circulation 110 2004 3115 3120
-
(2004)
Circulation
, vol.110
, pp. 3115-3120
-
-
Bauer, A.1
-
93
-
-
0035942250
-
Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1
-
U.C. Hoppe Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1 Proc. Natl. Acad. Sci. U. S. A. 98 2001 5335 5340
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 5335-5340
-
-
Hoppe, U.C.1
-
94
-
-
0036173169
-
Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility
-
I.L. Ennis Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility J. Clin. Invest. 109 2002 393 400
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 393-400
-
-
Ennis, I.L.1
-
95
-
-
4444370799
-
Gene therapy clinical trials worldwide 1989-2002 - An overview
-
M.L. Edelstein Gene therapy clinical trials worldwide 1989-2002 - an overview J. Gene Med. 6 2004 597 602
-
(2004)
J. Gene Med.
, vol.6
, pp. 597-602
-
-
Edelstein, M.L.1
-
96
-
-
0037133624
-
Angiogenic gene therapy (AGENT) trial in patients with stable angina pectoris
-
C.L. Grines Angiogenic gene therapy (AGENT) trial in patients with stable angina pectoris Circulation 105 2002 1291 1297
-
(2002)
Circulation
, vol.105
, pp. 1291-1297
-
-
Grines, C.L.1
-
97
-
-
3543025721
-
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral artery disease
-
R. Morishita Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral artery disease Hypertension 44 2004 203 209
-
(2004)
Hypertension
, vol.44
, pp. 203-209
-
-
Morishita, R.1
-
98
-
-
0033619428
-
Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomized, controlled trial
-
M.J. Mann Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomized, controlled trial Lancet 354 1999 1493 1498
-
(1999)
Lancet
, vol.354
, pp. 1493-1498
-
-
Mann, M.J.1
-
99
-
-
0035904829
-
Molecular decoy may keep bypass grafts open
-
M. McCarthy Molecular decoy may keep bypass grafts open Lancet 358 2001 1703
-
(2001)
Lancet
, vol.358
, pp. 1703
-
-
McCarthy, M.1
-
100
-
-
3242660757
-
Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure
-
N.C. Lai Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure Circulation 110 2004 330 336
-
(2004)
Circulation
, vol.110
, pp. 330-336
-
-
Lai, N.C.1
-
101
-
-
0034619585
-
Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity
-
N.C. Lai Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity Circulation 102 2000 2396 2401
-
(2000)
Circulation
, vol.102
, pp. 2396-2401
-
-
Lai, N.C.1
|