메뉴 건너뛰기




Volumn 246, Issue 1, 1997, Pages 186-192

Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment

Author keywords

Doxorubicin; Induction; Liver cells; Multidrug resistance; P glycoprotein

Indexed keywords

DOXORUBICIN; GLYCOPROTEIN P; MESSENGER RNA;

EID: 0030916246     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.t01-1-00186.x     Document Type: Article
Times cited : (62)

References (50)
  • 1
    • 0022620341 scopus 로고
    • cDNA clones for liver cytochrome P-450s from individual aroclor-treated rats: Constitutive expression of a new P-450 gene related to phenobarbital-inducible forms
    • Affolter, M., Labbe, D., Jean, A., Raymond, M., Noel, D., Labelle, Y., Parent-Vaugeois, C., Lambert, M., Bojanowski, R. & Anderson, A. (1986) cDNA clones for liver cytochrome P-450s from individual aroclor-treated rats: constitutive expression of a new P-450 gene related to phenobarbital-inducible forms. DNA 5, 209-218.
    • (1986) DNA , vol.5 , pp. 209-218
    • Affolter, M.1    Labbe, D.2    Jean, A.3    Raymond, M.4    Noel, D.5    Labelle, Y.6    Parent-Vaugeois, C.7    Lambert, M.8    Bojanowski, R.9    Anderson, A.10
  • 2
    • 0022446621 scopus 로고
    • Comparison of three actin-coding sequences in the mouse; evolutionary relationship between the actin genes of warm-blooded vertebrates
    • Alonso, S., Minhty, A., Bourlet, Y. & Buckingham, M. (1986) Comparison of three actin-coding sequences in the mouse; evolutionary relationship between the actin genes of warm-blooded vertebrates, J. Mol. Evol. 23, 11-22.
    • (1986) J. Mol. Evol. , vol.23 , pp. 11-22
    • Alonso, S.1    Minhty, A.2    Bourlet, Y.3    Buckingham, M.4
  • 3
    • 0028189510 scopus 로고
    • Multidrug resistance in the laboratory and clinic
    • Bellamy, W. T. & Dalton, W. S. (1994) Multidrug resistance in the laboratory and clinic, Adv. Clin. Chem. 31, 1-61.
    • (1994) Adv. Clin. Chem. , vol.31 , pp. 1-61
    • Bellamy, W.T.1    Dalton, W.S.2
  • 4
    • 0021321955 scopus 로고
    • A rapid, sensitive method for detection of alkaline phosphatase conjugated anti-antibody on western blots
    • Blake, M. S., Johnston, K. S., Russel-Jones, G. J. & Gotschlich, E. C. (1984) A rapid, sensitive method for detection of alkaline phosphatase conjugated anti-antibody on western blots, Anal. Biochem. 136, 175-179.
    • (1984) Anal. Biochem. , vol.136 , pp. 175-179
    • Blake, M.S.1    Johnston, K.S.2    Russel-Jones, G.J.3    Gotschlich, E.C.4
  • 5
    • 0023689651 scopus 로고
    • Conduction of MDR-1 multidrug-resistance and cytochrome P-450 genes in rat liver by xenobiotics
    • Burt, R. K. & Thorgeirsson, S. S. (1988) Conduction of MDR-1 multidrug-resistance and cytochrome P-450 genes in rat liver by xenobiotics, J. Natl Cancer Inst. 80, 1383-1386.
    • (1988) J. Natl Cancer Inst. , vol.80 , pp. 1383-1386
    • Burt, R.K.1    Thorgeirsson, S.S.2
  • 6
    • 0023130372 scopus 로고
    • Evaluation of a tetrazolium-based semi-automated colorimetric assay: Assessment of chemosensitivity testing
    • Carmichael, J., DeGraff, W. G., Gazdar, A. F., Minna, J. D. & Mitchell, J. B. (1987) Evaluation of a tetrazolium-based semi-automated colorimetric assay: assessment of chemosensitivity testing, Cancer Res. 47, 936-942.
    • (1987) Cancer Res. , vol.47 , pp. 936-942
    • Carmichael, J.1    DeGraff, W.G.2    Gazdar, A.F.3    Minna, J.D.4    Mitchell, J.B.5
  • 7
    • 0027506202 scopus 로고
    • Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs
    • Chaudhary, P. M. & Roninson, I. B. (1993) Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs, J. Natl Cancer Inst. 85, 632-639.
    • (1993) J. Natl Cancer Inst. , vol.85 , pp. 632-639
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 8
    • 0028024166 scopus 로고
    • Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection
    • Chen, G., Jaffrézou, J. P., Fleming, W. H., Duran, G. E. & Sikic, B. I. (1994) Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection, Cancer Res. 54, 4980-4987.
    • (1994) Cancer Res. , vol.54 , pp. 4980-4987
    • Chen, G.1    Jaffrézou, J.P.2    Fleming, W.H.3    Duran, G.E.4    Sikic, B.I.5
  • 9
    • 0025477701 scopus 로고
    • Regulation of mdr RNA levels in response to cytotoxic drugs in rodent cells
    • Chin, K. V., Chauchan, S. S., Pastan, I. & Gottesman, M. M. (1990) Regulation of mdr RNA levels in response to cytotoxic drugs in rodent cells, Cell Growth Differ. 1, 361-365.
    • (1990) Cell Growth Differ. , vol.1 , pp. 361-365
    • Chin, K.V.1    Chauchan, S.S.2    Pastan, I.3    Gottesman, M.M.4
  • 10
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin, J. M., Przybyla, E. A., MacDonald, R. J. & Rutter, W. J. (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry 18, 5294-5299.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Przybyla, E.A.2    MacDonald, R.J.3    Rutter, W.J.4
  • 11
    • 0018380350 scopus 로고
    • Inhibition of chicken myeloblastosis RNA polymerase II activity by adriamycin
    • Chuang, R. Y. & Chuang, L. F. (1979) Inhibition of chicken myeloblastosis RNA polymerase II activity by adriamycin, Biochemistry 18, 2069-2073.
    • (1979) Biochemistry , vol.18 , pp. 2069-2073
    • Chuang, R.Y.1    Chuang, L.F.2
  • 12
    • 0026503191 scopus 로고
    • Overexpression of the multidrug resistance gene product in adult rat hepatocytes during primary culture
    • Fardel, O., Ratanasavanh, D., Loyer, P., Ketterer, B. & Guillouzo, A. (1992) Overexpression of the multidrug resistance gene product in adult rat hepatocytes during primary culture, Eur. J. Biochem. 205, 847-852.
    • (1992) Eur. J. Biochem. , vol.205 , pp. 847-852
    • Fardel, O.1    Ratanasavanh, D.2    Loyer, P.3    Ketterer, B.4    Guillouzo, A.5
  • 13
    • 0028047406 scopus 로고
    • Constitutive expression of functional P-glycoprotein in rat hepatoma cells
    • Fardel, O., Loyer, P., Lecureur, V., Glaise, D. & Guillouzo, A. (1994) Constitutive expression of functional P-glycoprotein in rat hepatoma cells, Eur. J. Biochem. 219, 521-528.
    • (1994) Eur. J. Biochem. , vol.219 , pp. 521-528
    • Fardel, O.1    Loyer, P.2    Lecureur, V.3    Glaise, D.4    Guillouzo, A.5
  • 14
    • 0030051562 scopus 로고    scopus 로고
    • P-glycoprotein induction in rat liver epithelial cells in response to acute 3-methylcholanthrene treatment
    • Fardel, O., Lecureur, V., Corlu, A. & Guillouzo, A. (1996) P-glycoprotein induction in rat liver epithelial cells in response to acute 3-methylcholanthrene treatment, Biochem. Pharmacol. 51, 1427-1436.
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 1427-1436
    • Fardel, O.1    Lecureur, V.2    Corlu, A.3    Guillouzo, A.4
  • 15
    • 0006390439 scopus 로고
    • Pharmacology of drugs that alter multidrug resistance in cancer
    • Ford, J. M. & Hait, W. N. (1990) Pharmacology of drugs that alter multidrug resistance in cancer, Pharmacol. Rev. 8, 137-171.
    • (1990) Pharmacol. Rev. , vol.8 , pp. 137-171
    • Ford, J.M.1    Hait, W.N.2
  • 16
    • 0026327875 scopus 로고
    • Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver
    • Gant, T. W., Silverman, J. A., Bisgaard, H. C., Burt, R. K., Marino, P. & Thorgeirsson, S. S. (1991) Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver, Mol. Carcinog. 4, 499-509.
    • (1991) Mol. Carcinog. , vol.4 , pp. 499-509
    • Gant, T.W.1    Silverman, J.A.2    Bisgaard, H.C.3    Burt, R.K.4    Marino, P.5    Thorgeirsson, S.S.6
  • 17
    • 0026764538 scopus 로고
    • Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressor
    • Gant, T. W., Silverman, J. A. & Thorgeirsson S. S. (1992) Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressor, Nucleic Acids Res. 20, 2841-2846.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 2841-2846
    • Gant, T.W.1    Silverman, J.A.2    Thorgeirsson, S.S.3
  • 18
    • 0024523014 scopus 로고
    • Expression of a multidrug resistance-adenosine deaminase fusion gene
    • Germann, U. A., Gottesman, M. M. & Pastan, I. (1989) Expression of a multidrug resistance-adenosine deaminase fusion gene, J. Biol. Chem. 264, 7418-7424.
    • (1989) J. Biol. Chem. , vol.264 , pp. 7418-7424
    • Germann, U.A.1    Gottesman, M.M.2    Pastan, I.3
  • 19
    • 0027218689 scopus 로고
    • Biochemistry of MDR mediated hy the multidrug transporter
    • Gottesman, M. M. & Pastan, I. (1993) Biochemistry of MDR mediated hy the multidrug transporter, Annu. Rev. Biochem. 62, 385-427.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 20
    • 0023241702 scopus 로고
    • Biosynthesis of heterogenous forms of multidrug resistance-associated glycoproteins
    • Greenberger, L. M., Williams, S. S. & Horwitz, S. B. (1987) Biosynthesis of heterogenous forms of multidrug resistance-associated glycoproteins, J. Biol. Chem. 262, 13685-13689.
    • (1987) J. Biol. Chem. , vol.262 , pp. 13685-13689
    • Greenberger, L.M.1    Williams, S.S.2    Horwitz, S.B.3
  • 21
    • 0020660763 scopus 로고
    • Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type
    • Guguen-Guillouzo, C., Clément, B., Baffet, G., Beaumont, C., Morel-Chany, E., Glaise, D. & Guillouzo, A. (1983) Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type, Exp. Cell Res. 143, 47-54.
    • (1983) Exp. Cell Res. , vol.143 , pp. 47-54
    • Guguen-Guillouzo, C.1    Clément, B.2    Baffet, G.3    Beaumont, C.4    Morel-Chany, E.5    Glaise, D.6    Guillouzo, A.7
  • 23
    • 0028032146 scopus 로고
    • The effect of MDR-1 gene expression on outcome in acute myeloblastic leukemia
    • Holmes, J. A. & West, R. R. (1994) The effect of MDR-1 gene expression on outcome in acute myeloblastic leukemia, Br. J. Cancer 69, 382-384.
    • (1994) Br. J. Cancer , vol.69 , pp. 382-384
    • Holmes, J.A.1    West, R.R.2
  • 24
    • 0029017629 scopus 로고
    • Rapid upregulation of MDR1 expression by anthracyclines in a classical multidrug-resistant cell line
    • Hu, X. F., Slater, S., Wall, D. M., Kantharidis, P., Pakin, J. D., Cowman, A. & Zalcberg, J. R. (1995) Rapid upregulation of MDR1 expression by anthracyclines in a classical multidrug-resistant cell line, Br. J. Cancer 71, 931-936.
    • (1995) Br. J. Cancer , vol.71 , pp. 931-936
    • Hu, X.F.1    Slater, S.2    Wall, D.M.3    Kantharidis, P.4    Pakin, J.D.5    Cowman, A.6    Zalcberg, J.R.7
  • 25
    • 0026524781 scopus 로고
    • Overexpression of the MDR1 gene and P-glycoprotein in human hepatocellular carcinoma
    • Huang, C., Wu, M., Xu, G., Li, D., Cheng, H., Tu, Z., Jiang, H. & Gu, J. (1992) Overexpression of the MDR1 gene and P-glycoprotein in human hepatocellular carcinoma, J. Natl Cancer Inst. 84, 262-264.
    • (1992) J. Natl Cancer Inst. , vol.84 , pp. 262-264
    • Huang, C.1    Wu, M.2    Xu, G.3    Li, D.4    Cheng, H.5    Tu, Z.6    Jiang, H.7    Gu, J.8
  • 26
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano, R. L. & Ling, V. (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants, Biochem. Biophys. Acta 455, 152-162.
    • (1976) Biochem. Biophys. Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 27
    • 0021852930 scopus 로고
    • Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies
    • Kartner, N., Evernden-Porelle, D., Bradley, G. & Ling, V. (1985) Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies, Nature 316, 820-823.
    • (1985) Nature , vol.316 , pp. 820-823
    • Kartner, N.1    Evernden-Porelle, D.2    Bradley, G.3    Ling, V.4
  • 28
    • 0029952006 scopus 로고    scopus 로고
    • Differential regulation of mdr genes in response to 2-acetylaminofluorene treatment in cultured rat and human hepatocytes
    • Lecureur, V., Guillouzo, A. & Fardel, O. (1996) Differential regulation of mdr genes in response to 2-acetylaminofluorene treatment in cultured rat and human hepatocytes, Carcinogenesis 17, 1157-1160.
    • (1996) Carcinogenesis , vol.17 , pp. 1157-1160
    • Lecureur, V.1    Guillouzo, A.2    Fardel, O.3
  • 29
    • 0027493626 scopus 로고
    • Differential expression of P-glycoprotein genes in primary rat hepatocyte culture
    • Lee, C. H., Bradley, G., Zhang, J.-T. & Ling, V. (1993) Differential expression of P-glycoprotein genes in primary rat hepatocyte culture, J. Cell. Physiol. 157, 392-402.
    • (1993) J. Cell. Physiol. , vol.157 , pp. 392-402
    • Lee, C.H.1    Bradley, G.2    Zhang, J.-T.3    Ling, V.4
  • 30
    • 0028966586 scopus 로고
    • Overexpression of the class II P-glycoprotein gene in primary rat hepatocyte culture: Evidence for increased mRNA stability
    • Lee, C. H., Bradley, G. & Ling, V. (1995) Overexpression of the class II P-glycoprotein gene in primary rat hepatocyte culture: evidence for increased mRNA stability, Cell Growth & Differ. 6, 374-354.
    • (1995) Cell Growth & Differ. , vol.6 , pp. 374-1354
    • Lee, C.H.1    Bradley, G.2    Ling, V.3
  • 32
    • 0028029862 scopus 로고
    • Influence of nidogen complexed or not with laminin on attachment, spreading, and albumin and laminin B2 mRNA levels of rat hepatocytes
    • Levavasseur, F., Mayer, U., Guillouzo, A. & Clement, B. (1994) Influence of nidogen complexed or not with laminin on attachment, spreading, and albumin and laminin B2 mRNA levels of rat hepatocytes, J. Cell. Physiol. 161, 257-266.
    • (1994) J. Cell. Physiol. , vol.161 , pp. 257-266
    • Levavasseur, F.1    Mayer, U.2    Guillouzo, A.3    Clement, B.4
  • 33
    • 0023833803 scopus 로고
    • Use of fluorescent dyes as molecular probes for the study of multidrug resistance
    • Neyfakh, A. A. (1988) Use of fluorescent dyes as molecular probes for the study of multidrug resistance, Exp. Cell Res. 174, 168-176.
    • (1988) Exp. Cell Res. , vol.174 , pp. 168-176
    • Neyfakh, A.A.1
  • 35
    • 0026527353 scopus 로고
    • The role of transcription and messenger RNA stability in the regulation of epidermal growth factor receptor gene expression in regenerating mouse liver
    • Noguchi, S., Ohba, Y. & Oka, T. (1992) The role of transcription and messenger RNA stability in the regulation of epidermal growth factor receptor gene expression in regenerating mouse liver, Hepatology 15, 88-96.
    • (1992) Hepatology , vol.15 , pp. 88-96
    • Noguchi, S.1    Ohba, Y.2    Oka, T.3
  • 36
    • 0025828251 scopus 로고
    • Multidrug resistance (mdr) in human cancer
    • Nooter, K. & Herweijer, H. (1991) Multidrug resistance (mdr) in human cancer, Br. J. Cancer 63, 663-669.
    • (1991) Br. J. Cancer , vol.63 , pp. 663-669
    • Nooter, K.1    Herweijer, H.2
  • 37
    • 0025055648 scopus 로고
    • Enzyme induction in the cytochrome P-450 system
    • Okey, A. B. (1990) Enzyme induction in the cytochrome P-450 system, Pharmacol. Ther. 45, 241-298.
    • (1990) Pharmacol. Ther. , vol.45 , pp. 241-298
    • Okey, A.B.1
  • 38
    • 0021797892 scopus 로고
    • Amplification of P-glycoprotein genes in multidrug resistant mammalian cell lines
    • Riordan, J. R., Deuchars, K., Kartner, N., Alar, N., Trent, J. & Ling, V. (1985) Amplification of P-glycoprotein genes in multidrug resistant mammalian cell lines, Nature 316, 817-819.
    • (1985) Nature , vol.316 , pp. 817-819
    • Riordan, J.R.1    Deuchars, K.2    Kartner, N.3    Alar, N.4    Trent, J.5    Ling, V.6
  • 39
    • 0026570652 scopus 로고
    • The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo
    • Roninson, I. B. (1992) The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo, Biochem. Pharmacol. 43, 95-102.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 95-102
    • Roninson, I.B.1
  • 41
    • 0027299120 scopus 로고
    • Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates
    • Schrenk, D., Gant, T. W., Preisegger, K.-H., Silverman, J. A., Marino, P. A. & Thorgeirsson, S. S. (1993) Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates, Hepatology 17, 854-860.
    • (1993) Hepatology , vol.17 , pp. 854-860
    • Schrenk, D.1    Gant, T.W.2    Preisegger, K.-H.3    Silverman, J.A.4    Marino, P.A.5    Thorgeirsson, S.S.6
  • 42
    • 0029616617 scopus 로고
    • Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms
    • Schuetz, E. G., Furuya, K. N. & Schuetz, J. D. (1995) Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms, J. Exp. Pharmacol. Ther. 275, 1011-1018.
    • (1995) J. Exp. Pharmacol. Ther. , vol.275 , pp. 1011-1018
    • Schuetz, E.G.1    Furuya, K.N.2    Schuetz, J.D.3
  • 43
    • 0023236652 scopus 로고
    • Differential formations of hydroxide radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: Implication for the mechanism of action
    • Sinha, B. K., Katki, A. G., Batist, G., Cowan, K. H. & Myers, C. E. (1987) Differential formations of hydroxide radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implication for the mechanism of action, Biochemistry 26, 3776-3781.
    • (1987) Biochemistry , vol.26 , pp. 3776-3781
    • Sinha, B.K.1    Katki, A.G.2    Batist, G.3    Cowan, K.H.4    Myers, C.E.5
  • 44
    • 0027377964 scopus 로고
    • Activation of distinct multidrug resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis
    • Teeter, L. D., Estes, M., Chan, J. Y., Atassi, H., Sell, S., Becker, F. F. & Kuo, M. T. (1993) Activation of distinct multidrug resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis, Mol. Carcinog. 8, 67-73.
    • (1993) Mol. Carcinog. , vol.8 , pp. 67-73
    • Teeter, L.D.1    Estes, M.2    Chan, J.Y.3    Atassi, H.4    Sell, S.5    Becker, F.F.6    Kuo, M.T.7
  • 45
    • 0021151237 scopus 로고
    • Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II
    • Tewey, K. M., Rowe, T. C., Yang, B. D., Haligan, B. D. & Liu, L. F. (1984), Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II, Science 226, 466-468.
    • (1984) Science , vol.226 , pp. 466-468
    • Tewey, K.M.1    Rowe, T.C.2    Yang, B.D.3    Haligan, B.D.4    Liu, L.F.5
  • 47
    • 0023217079 scopus 로고
    • Hepatocarcinomas, cholangiocarcinomas and hepatoblastomas produced by chemically transformed cultured rat liver epithelial cells
    • Tsao, M. S. & Grisham, J. W. (1987) Hepatocarcinomas, cholangiocarcinomas and hepatoblastomas produced by chemically transformed cultured rat liver epithelial cells, Cancer Res. 127, 168-181.
    • (1987) Cancer Res. , vol.127 , pp. 168-181
    • Tsao, M.S.1    Grisham, J.W.2
  • 48
    • 0026487058 scopus 로고
    • Human P-glycoprotein transports Cortisol, aldosterone and dexamethasone, but not progesterone
    • Ueda, K., Okamura, N., Hirai, M., Tanigawara, Y., Saecki, T., Kioka, N., Komano, T. & Hori, R. (1992) Human P-glycoprotein transports Cortisol, aldosterone and dexamethasone, but not progesterone, J. Biol. Chem. 267, 24248-24252.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24248-24252
    • Ueda, K.1    Okamura, N.2    Hirai, M.3    Tanigawara, Y.4    Saecki, T.5    Kioka, N.6    Komano, T.7    Hori, R.8
  • 50
    • 0015153182 scopus 로고
    • Isolation and long-term cell culture of epithelial like cells from rat liver
    • Williams, G. M., Weisburger, E. K. & Weisburger, J. H. (1971) Isolation and long-term cell culture of epithelial like cells from rat liver, Exp. Cell Res. 69, 106-112.
    • (1971) Exp. Cell Res. , vol.69 , pp. 106-112
    • Williams, G.M.1    Weisburger, E.K.2    Weisburger, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.