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Volumn 80, Issue 6, 2002, Pages 646-652

Efficient synthesis of the optically active dihydropyrimidinone of a potent α1A-selective adrenoceptor antagonist

(14) Sidler, Daniel R a Barta, Nancy a Li, Wenjie a Hu, Essa a Matty, Louis a Ikemoto, Nori a Campbell, Jeffrey S a Chartrain, Michel a Gbewonyo, Kozo a Boyd, Russell a Corley, Edward G a Ball, Richard G a Larsen, Robert D a Reider, Paul J a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

Dihydropyrimidinone; Enzymatic resolution; Palladium coupling

Indexed keywords

ENZYMES; PALLADIUM; SYNTHESIS (CHEMICAL);

COUPLING REACTION;

CHEMICAL ENGINEERING;

2,4' DIPYRIDYL; ADRENERGIC RECEPTOR BLOCKING AGENT; DIHYDROPYRIMIDINONE; PALLADIUM; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DIASTEREOISOMER; DRUG POTENCY; DRUG SYNTHESIS; ENANTIOMER; STEREOCHEMISTRY;

EID: 18544379145 PISSN: 00084042 EISSN: None Source Type: Journal
DOI: 10.1139/v02-079 Document Type: Article

Times cited : (24)

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