Early stimulation and late inhibition of peroxisome proliferator-activated receptor γ (PPARγ) gene expression by transformino growth factor β in human aortic smooth muscle cells: Role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads

Biochemical Journal

Volumn 370, Issue 3, 2003, Pages 1019-1025

  Fu, Mingui ^a   Zhang, Jifeng ^a   Lin, Yimin ^a   Zhu, Xiaojun ^a   Zhao, Luning ^a   Ahmad, Mushtaq ^b   Ehrengruber, Markus U ^c   Chen, Yuqing E ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Atherosclerosis; Peroxisome proliferator activated receptor (PPAR ); Signal transduction; Transcriptional factor; Transforming growth factor (TGF )

Indexed keywords

CELLS; ENZYME INHIBITION; GAMMA RAYS; GENETIC ENGINEERING; GROWTH KINETICS;

VASCULAR SMOOTH MUSCLE CELLS;

MUSCLE;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; EARLY GROWTH RESPONSE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN C JUN; SMAD PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA;

AORTA MEDIA; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR GENE; REPRESSOR GENE; SIGNAL TRANSDUCTION; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE;

AORTA; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERLEUKIN-1; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PLATELET-DERIVED GROWTH FACTOR; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA STABILITY; SIGNAL TRANSDUCTION; SMAD PROTEINS; TETRADECANOYLPHORBOL ACETATE; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

ADENOVIRIDAE;

EID: 0037444798     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021503     Document Type: Article

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