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Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 6, 2002, Pages 923-928

Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: The insertion of an (E)-alkene dipeptide isostere into the βII′-turn moiety

(11) Tamamura, Hirokazu a Hiramatsu, Kenichi a Miyamoto, Kazuhide a Omagari, Akane a Oishi, Shinya a Nakashima, Hideki b Yamamoto, Naoki c Kuroda, Yoshihiro a Nakagawa, Terumichi a Otaka, Akira a Fujii, Nobutaka a

a KYOTO UNIVERSITY (Japan)

b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE (Japan)

c TOKYO MEDICAL AND DENTAL UNIVERSITY (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CHEMOKINE RECEPTOR CXCR4; DIPEPTIDE; OLIGOPEPTIDE; T 140; ALKENE DERIVATIVE; DIPEPTIDE DERIVATIVE; PSEUDOPEPTIDE; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; CALCIUM SIGNALING; CELL CULTURE; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; MICROBIOLOGICAL EXAMINATION; PROTEIN SECONDARY STRUCTURE; SYNTHESIS; ANIMAL CELL; ANTIVIRAL ACTIVITY; BETA SHEET; CALCIUM MOBILIZATION; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG DESIGN; DRUG SCREENING; DRUG SPECIFICITY; DRUG SYNTHESIS; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN FUNCTION;

ANTI-HIV AGENTS; CALCIUM SIGNALING; CELL DIVISION; DIPEPTIDES; HIV-1; HUMANS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CXCR4; TUMOR CELLS, CULTURED;

HUMAN IMMUNODEFICIENCY VIRUS 1; INSERTION SEQUENCES;

EID: 18344368807 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(02)00041-0 Document Type: Article

Times cited : (38)

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