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Volumn 281, Issue 2, 1997, Pages 921-927

Effects of a novel free radical scavenger, MCI-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model

Author keywords

[No Author keywords available]

Indexed keywords

2 OXO 3 (PHENYLHYDRAZONO)BUTANOIC ACID; DRUG METABOLITE; NORPHENAZONE; SCAVENGER; UNCLASSIFIED DRUG;

EID: 0030979729     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (254)

References (35)
  • 1
    • 0023947826 scopus 로고
    • Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger
    • ABE, K., YUKI, S. AND KOGURE, K.: Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger. Stroke 19: 480-485, 1988.
    • (1988) Stroke , vol.19 , pp. 480-485
    • Abe, K.1    Yuki, S.2    Kogure, K.3
  • 2
    • 0029018859 scopus 로고
    • Three-dimensional image analysis of brain glucose metabolism-blood flow uncoupling and its electrophysiological correlates in the acute ischemic penumbra following middle cerebral artery occlusion
    • BACK, T., ZHAO, W. AND GINSBERG, M.D.: Three-dimensional image analysis of brain glucose metabolism-blood flow uncoupling and its electrophysiological correlates in the acute ischemic penumbra following middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 15: 566-577, 1995.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 566-577
    • Back, T.1    Zhao, W.2    Ginsberg, M.D.3
  • 3
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • BEDERSON, J. B., PITTS, L. H., TSUJI, M., NISHIMUR, M. C., DAVIS, R. L. AND BARTOWSKI, H.: Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17: 472-476, 1986.
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3    Nishimur, M.C.4    Davis, R.L.5    Bartowski, H.6
  • 4
    • 0028181531 scopus 로고
    • α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia
    • CAO, X., AND PHILLIS, J. W.: α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia. Brain Res. 644: 267-272, 1994.
    • (1994) Brain Res. , vol.644 , pp. 267-272
    • Cao, X.1    Phillis, J.W.2
  • 5
    • 0026647358 scopus 로고
    • Antioxidant-dependent amelioration of brain injury: Role of CuZn-superoxide dismutase
    • CHAN, H.: Antioxidant-dependent amelioration of brain injury: role of CuZn-superoxide dismutase. J. Neurotrauma 9: suppl. 2, S417-S423, 1992.
    • (1992) J. Neurotrauma , vol.9 , Issue.2 SUPPL.
    • Chan, H.1
  • 6
    • 0022545394 scopus 로고
    • A model of focal ischemic stroke in the rat: Reproducible extensive cortical infarction
    • CHEN, S. T., HSU, C. Y., HOGAN, E. L., MARICQ, H. AND BALENTINE, J. D.: A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke 17: 738-743, 1986.
    • (1986) Stroke , vol.17 , pp. 738-743
    • Chen, S.T.1    Hsu, C.Y.2    Hogan, E.L.3    Maricq, H.4    Balentine, J.D.5
  • 9
    • 0026077959 scopus 로고
    • Glutamate, nitric oxide and cell-cell signaling in the nervous system
    • GARTHWAITE, J.: Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends Neurosci. 14: 60-67, 1991.
    • (1991) Trends Neurosci. , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 10
    • 0012891934 scopus 로고
    • Oxygen radical and excitotoxic processes in brain ischemia and trauma
    • ed. by J. Krieglstein and S. H. Oberpichler, Wissenschaftliche Verlagsgesellschaft, Stuttgart
    • GINSBERG, M. D., GLOBUS, M. Y-T., MARTINEZ, E., MORIMOTO, T., LIN, B., SCHNIPPERING, H., ALONSO, O. F. AND BUSTO, R.: Oxygen radical and excitotoxic processes in brain ischemia and trauma. In Pharmacology of Cerebral ischemia, ed. by J. Krieglstein and S. H. Oberpichler, pp. 255-268, Wissenschaftliche Verlagsgesellschaft, Stuttgart, 1994.
    • (1994) Pharmacology of Cerebral Ischemia , pp. 255-268
    • Ginsberg, M.D.1    Globus, M.Y.-T.2    Martinez, E.3    Morimoto, T.4    Lin, B.5    Schnippering, H.6    Alonso, O.F.7    Busto, R.8
  • 11
    • 0026772608 scopus 로고
    • Time course of cerebral blood flow and histological outcome after focal cerebral ischemia in rats
    • HAKIM, A. M., HOGAN, M. J. AND CARPENTER, S.: Time course of cerebral blood flow and histological outcome after focal cerebral ischemia in rats. Stroke 23: 1138-1144, 1992.
    • (1992) Stroke , vol.23 , pp. 1138-1144
    • Hakim, A.M.1    Hogan, M.J.2    Carpenter, S.3
  • 12
    • 0025074716 scopus 로고
    • Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats
    • IMAIZUMI, S., WOOLWORTH, V., FISHMAN, R. A. AND CHAN, P. H.: Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats. Stroke 21: 1321-1317, 1990.
    • (1990) Stroke , vol.21 , pp. 1321-11317
    • Imaizumi, S.1    Woolworth, V.2    Fishman, R.A.3    Chan, P.H.4
  • 13
    • 0025838263 scopus 로고
    • Evaluation of 2,3,5-triphenyltetrazolium chloride staining to delineate rat brain infarcts
    • ISAYAMA, K., PITTS, L. H. AND NISHIMURA, M. C.: Evaluation of 2,3,5-triphenyltetrazolium chloride staining to delineate rat brain infarcts. Stroke 22: 1394-1398, 1991.
    • (1991) Stroke , vol.22 , pp. 1394-1398
    • Isayama, K.1    Pitts, L.H.2    Nishimura, M.C.3
  • 14
    • 0026345023 scopus 로고
    • Attenuation of focal cerebral ischemia injury in transgenic mice overexpressing CuZn superoxide dismutase
    • KINOUCHI, H., EPSTEIN, C. J., MIZUI, T., CARLSON, E., CHEN, S. F. AND CHAN, P. H.: Attenuation of focal cerebral ischemia injury in transgenic mice overexpressing CuZn superoxide dismutase. Proc. Natl. Acad. Sci. U.S.A. 88: 11158-11162, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 11158-11162
    • Kinouchi, H.1    Epstein, C.J.2    Mizui, T.3    Carlson, E.4    Chen, S.F.5    Chan, P.H.6
  • 16
    • 0027194540 scopus 로고
    • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
    • LIPTON, S. A., CHOI, Y. B., PAN, Z. H., LEI, S. Z., CHEN, H. S. V., SUCHER, N. J., LOSCALZO, J., SINGLE, D. J. AND STAMLER, J. S.: A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364: 626-632, 1993.
    • (1993) Nature , vol.364 , pp. 626-632
    • Lipton, S.A.1    Choi, Y.B.2    Pan, Z.H.3    Lei, S.Z.4    Chen, H.S.V.5    Sucher, N.J.6    Loscalzo, J.7    Single, D.J.8    Stamler, J.S.9
  • 17
    • 0027463828 scopus 로고
    • Comparative histopathologic consequences of photothrombotic occlusion of the distal middle cerebral artery in Sprague-Dawley and wistar rat
    • MARKGRAF, C. G., KRAYDIEH, S., PRADO, R., WATSON, B. D., DIETRICH, W. D. AND GINSBERG, M. D.: Comparative histopathologic consequences of photothrombotic occlusion of the distal middle cerebral artery in Sprague-Dawley and wistar rat. Stroke 24: 286-293, 1993.
    • (1993) Stroke , vol.24 , pp. 286-293
    • Markgraf, C.G.1    Kraydieh, S.2    Prado, R.3    Watson, B.D.4    Dietrich, W.D.5    Ginsberg, M.D.6
  • 18
    • 0027247636 scopus 로고
    • A simple and reproducible cerebral thrombosis model in rats induced by a photochemical reaction and the effect of a plasminogen-plasminogen activator chimera in this model
    • MATSUNO, H., UEMATSU, T., UMEMURA, K., TAKIGUCHI, Y., ASAI, Y., MURANAKA, Y. AND NAKASHIMA, M.: A simple and reproducible cerebral thrombosis model in rats induced by a photochemical reaction and the effect of a plasminogen-plasminogen activator chimera in this model. J. Pharmacol. Toxicol. Methods 29: 165-173, 1993.
    • (1993) J. Pharmacol. Toxicol. Methods , vol.29 , pp. 165-173
    • Matsuno, H.1    Uematsu, T.2    Umemura, K.3    Takiguchi, Y.4    Asai, Y.5    Muranaka, Y.6    Nakashima, M.7
  • 19
    • 0030028586 scopus 로고    scopus 로고
    • Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats
    • MORIMOTO, T., GLOBUS, M. Y-T., BUSTO, R., MARTINEZ, E. AND GINSBERG, M. D.: Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. 16: 92-99, 1996.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 92-99
    • Morimoto, T.1    Globus, M.Y.-T.2    Busto, R.3    Martinez, E.4    Ginsberg, M.D.5
  • 20
    • 0025684851 scopus 로고
    • The control of vascular endothelial injury
    • MUROTA, S., MORITA, I. AND SUDA, N.: The control of vascular endothelial injury. Ann. NY Acad. Sci. 598: 182-187, 1990.
    • (1990) Ann. NY Acad. Sci. , vol.598 , pp. 182-187
    • Murota, S.1    Morita, I.2    Suda, N.3
  • 22
    • 0025923211 scopus 로고
    • Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats
    • OH, S. M. AND BETZ, A. L.: Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats. Stroke 22: 915-921, 1991.
    • (1991) Stroke , vol.22 , pp. 915-921
    • Oh, S.M.1    Betz, A.L.2
  • 23
    • 0024462418 scopus 로고
    • Effect of MCI-186 on ischemia-induced changes in monoamine metabolism in rat brain
    • OISHI, T., ITOH, Y., NISHIBORI, M., WATANABE, T., NISHI, H. AND SAEKI, K.: Effect of MCI-186 on ischemia-induced changes in monoamine metabolism in rat brain. Stroke 20: 1557-1564, 1989.
    • (1989) Stroke , vol.20 , pp. 1557-1564
    • Oishi, T.1    Itoh, Y.2    Nishibori, M.3    Watanabe, T.4    Nishi, H.5    Saeki, K.6
  • 25
    • 0025351232 scopus 로고
    • Free radicals in central nervous system ischemia
    • SCHMIDLEY, J. W.: Free radicals in central nervous system ischemia. Stroke 21: 1086-1090, 1990.
    • (1990) Stroke , vol.21 , pp. 1086-1090
    • Schmidley, J.W.1
  • 27
    • 0026782517 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia, part II: Mechanisms of damage and treatment
    • SIESJO, B. K.: Pathophysiology and treatment of focal cerebral ischemia, part II: mechanisms of damage and treatment. J. Neurosurg. 77: 337-354, 1992.
    • (1992) J. Neurosurg. , vol.77 , pp. 337-354
    • Siesjo, B.K.1
  • 28
    • 0026669125 scopus 로고
    • Nitric oxide: First in a new class of neurotransmitters?
    • SYNDER, S. H.: Nitric oxide: First in a new class of neurotransmitters? Science 257: 464-466, 1992.
    • (1992) Science , vol.257 , pp. 464-466
    • Synder, S.H.1
  • 29
    • 0027196253 scopus 로고
    • Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: Correlation with histopathology
    • TAKAGI, K., GINSBERG, M. D., GLOBUS, M. Y-T., DIETRICH, W. D., MARTINEZ, E., KRAYDIEH, S. AND BUSTO, R.: Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: Correlation with histopathology. J. Cereb. Blood Flow Metab. 13: 575-585, 1993.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 575-585
    • Takagi, K.1    Ginsberg, M.D.2    Globus, M.Y.-T.3    Dietrich, W.D.4    Martinez, E.5    Kraydieh, S.6    Busto, R.7
  • 30
    • 0027216002 scopus 로고
    • Evaluation of the combination of a tissue-type plasminogen activator, SUN9216, and a thromboxane A2 receptor antagonist, vapiprost, in a rat middle cerebral artery thrombosis model
    • UMEMURA, K., WADA, T., UEMATSU, T. AND NAKASHIMA, M.: Evaluation of the combination of a tissue-type plasminogen activator, SUN9216, and a thromboxane A2 receptor antagonist, vapiprost, in a rat middle cerebral artery thrombosis model. Stroke 24: 1077-1082, 1993.
    • (1993) Stroke , vol.24 , pp. 1077-1082
    • Umemura, K.1    Wada, T.2    Uematsu, T.3    Nakashima, M.4
  • 31
    • 0023688132 scopus 로고
    • Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial cell injury in vitro
    • WATANABE, T., MORITA, I., NISHI, H., MUROTA, S.: Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial cell injury in vitro. Prostaglandins Leuko Essent Fatty Acids 33: 81-87, 1988.
    • (1988) Prostaglandins Leuko Essent Fatty Acids , vol.33 , pp. 81-87
    • Watanabe, T.1    Morita, I.2    Nishi, H.3    Murota, S.4
  • 32
    • 0028292964 scopus 로고
    • Protective effects of MCI-186 on cerebral ischemia: Possible involvement of free radical scavenging and antioxidant actions
    • WATANABE, T., YUKI, S., EGAWA, M. AND NISHI, H.: Protective effects of MCI-186 on cerebral ischemia: Possible involvement of free radical scavenging and antioxidant actions. J. Pharmacol. Exp. Ther. 268: 1597-1604, 1994a.
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 1597-1604
    • Watanabe, T.1    Yuki, S.2    Egawa, M.3    Nishi, H.4
  • 33
    • 0027967666 scopus 로고
    • Effects of an antistroke agent MCI-186 on cerebral arachidonate cascade
    • WATANABE, T. AND EGAWA, M.: Effects of an antistroke agent MCI-186 on cerebral arachidonate cascade. J. Pharmacol. Exp. Ther. 271: 1624-1629, 1994b.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 1624-1629
    • Watanabe, T.1    Egawa, M.2
  • 34
    • 0000393508 scopus 로고    scopus 로고
    • Antioxidation activity of 3-Methyl-1-phenyl-pyrazolin-5-one
    • YAMAMOTO, Y., KUWAHARA, T., WATANABE, K. AND WATANABE, K.: Antioxidation activity of 3-Methyl-1-phenyl-pyrazolin-5-one. Redox Report 2: 333-338, 1996.
    • (1996) Redox Report , vol.2 , pp. 333-338
    • Yamamoto, Y.1    Kuwahara, T.2    Watanabe, K.3    Watanabe, K.4
  • 35
    • 0021997646 scopus 로고
    • Regional lipid peroxidation in rat brain in vitro: Possible role of endogenous iron
    • ZALESKA, M. M. AND FLOYD, R. A.: Regional lipid peroxidation in rat brain in vitro: Possible role of endogenous iron. Neurochem. Res. 10: 397-410, 1985.
    • (1985) Neurochem. Res. , vol.10 , pp. 397-410
    • Zaleska, M.M.1    Floyd, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.