RH1 induces cellular damage in an NAD(P)H:quinone oxidoreductase 1-dependent manner: Relationship between DNA cross-linking, cell cycle perturbations, and apoptosis

Journal of Pharmacology and Experimental Therapeutics

Volumn 313, Issue 2, 2005, Pages 771-779

  Dehn, Donna L ^a   Inayat Hussain, Salmaan H ^a   Ross, David ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 DIAZIRIDINYL 3 (HYDROXYMETHYL) 6 METHYL 1,4 BENZOQUINONE; 5 METHOXY 1,2 DIMETHYL 3 [(4 NITROPHENOXY)METHYL]INDOLE 4,7 DIONE; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE; CASPASE 3; INDOLE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; RH 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DAMAGE; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA CROSS LINKING; DRUG MECHANISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

APOPTOSIS; AZIRIDINES; BENZOQUINONES; CELL CYCLE; CELL LINE, TUMOR; CROSS-LINKING REAGENTS; DNA; HUMANS; NAD(P)H DEHYDROGENASE (QUINONE);

EID: 18044364834     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.081380     Document Type: Article

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