Cytotoxicity and apoptosis of benzoquinones: Redox cycling, cytochrome c release, and BAD protein expression

Biochemical Pharmacology

Volumn 65, Issue 7, 2003, Pages 1061-1075

  Tudor, Gabriela ^a   Gutierrez, Peter ^b   Aguilera Gutierrez, Angelica ^a   Sausville, Edward A ^c  

^a SAIC FREDERICK INC   (United States)

^b UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Antitumor quinones; Apoptosis; BAD protein; Cytochrome c release; Hydroxyl radicals; NQO1; Redox cycling

Indexed keywords

ANTINEOPLASTIC AGENT; AZIRIDINYLBENZOQUINONE DERIVATIVE; CYTOCHROME C; PROTEIN BAD; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPATHOGENIC EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; STRUCTURE ANALYSIS;

EID: 0344953575     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00013-3     Document Type: Article

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