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Volumn 40, Issue 50, 2001, Pages 15135-15142

Characterization of a mechanism-based inhibitor of NAD(P)H:Quinone oxidoreductase 1 by biochemical, x-ray crystallographic, and mass spectrometric approaches

(10) Winski, S L a Faig, M b Bianchet, M A b Siegel, D a Swann, E c Fung, K a Duncan, M W a Moody, C J c Amzel, L M b Ross, D a

a UNIVERSITY OF COLORADO (United States)

b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (United States)

c UNIVERSITY OF EXETER (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE;

AMINO ACIDS; AROMATIC COMPOUNDS; BIOCHEMISTRY; COMPOSITION; KETONES; MASS SPECTROMETRY; MOLECULAR ORIENTATION; X RAY CRYSTALLOGRAPHY;

ENZYME INHIBITION;

5 METHOXY 1,2 DIMETHYL 3 [(4 NITROPHENOXY)METHYL]INDOLE 4,7 DIONE; AMINO ACID; ENZYME INHIBITOR; ES 936; HISTIDINE; IMINE; INDOLE DERIVATIVE; NITROPHENOL; PYRIDINE NUCLEOTIDE; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; COVALENT BOND; CRYSTAL STRUCTURE; DOSE TIME EFFECT RELATION; DRUG ACTIVATION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME STRUCTURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN DEGRADATION; REDUCTION; STRUCTURE ANALYSIS; THEORY; X RAY CRYSTALLOGRAPHY;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; INDOLEQUINONES; INDOLES; KINETICS; MODELS, MOLECULAR; NAD(P)H DEHYDROGENASE (QUINONE); PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0035909827 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi011324i Document Type: Article

Times cited : (86)

References (43)

1
- 77957000392
- (1967) Methods Enzymol. , vol.10 , pp. 309-317
- Ernster, L.¹

2
- 0020464384
- (1982) Arch. Biochem. Biophys. , vol.216 , pp. 178-185
- Lind, C.¹ Hochstein, P.² Emster, L.³

3
- 0020440918
- (1982) J. Biol. Chem. , vol.257 , pp. 12419-12425
- Thor, H.¹ Smith, M.T.² Hartzell, P.³ Bellomo, G.⁴ Jewell, S.A.⁵ Orrenius, S.⁶

4
- 9244256748
- (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 2528-2532
- Beyer, R.E.¹ Segura-Aguilar, J.² Di Bernardo, S.³ Cavazzoni, M.⁴ Fato, R.⁵ Fiorentini, D.⁶ Galli, M.⁷ Setti, M.⁸ Landi, L.⁹ Lenaz, G.¹⁰

5
- 0029859863
- (1997) Free Radical Biol. Med. , vol.22 , pp. 329-335
- Landi, L.¹ Fiorentini, D.² Galli, M.C.³ Segura-Aguilar, J.⁴ Beyer, R.E.⁵

6
- 0030739681
- (1997) Mol. Pharmacol. , vol.52 , pp. 300-305
- Siegel, D.¹ Bolton, E.M.² Burr, J.A.³ Liebler, D.C.⁴ Ross, D.⁵

7
- 0000692532
- (1964) J. Exp. Med. , vol.119 , pp. 923-942
- Huggins, C.¹ Fukunishi, R.²

8
- 0019142866
- (1980) Proc. Natl. Acad. Sci. U.S.A. , vol.77 , pp. 5216-5220
- Benson, A.M.¹ Hunkler, M.J.² Talalay, P.³

9
- 0344915418
- (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 8261-8265
- Talalay, P.¹ De Long, M.J.² Prochaska, H.J.³

10
- 0027295491
- (1993) Cancer Metastasis Rev. , vol.12 , pp. 83-101
- Ross, D.¹ Siegel, D.² Beall, H.³ Prakash, A.S.⁴ Mulcahy, R.T.⁵ Gibson, N.W.⁶

11
- 0028610410
- (1994) Oncol. Res. , vol.6 , pp. 493-500
- Ross, D.¹ Beall, H.² Traver, R.D.³ Siegel, D.⁴ Phillips, R.M.⁵ Gibson, N.W.⁶

12
- 0032435478
- (1998) Clin. Cancer Res. , vol.4 , pp. 3083-3088
- Winski, S.¹ Hargreaves, R.H.J.² Butler, J.³ Ross, D.⁴

13
- 0025248106
- (1990) Int. J. Cancer , vol.45 , pp. 403-409
- Schlager, J.J.¹ Powis, G.²

14
- 0026700546
- (1992) Cancer Res. , vol.52 , pp. 4752-4757
- Malkinson, A.M.¹ Siegel, D.² Forrest, G.L.³ Gazdar, A.F.⁴ Oie, H.K.⁵ Chan, D.C.⁶ Bunn, P.A.⁷ Mabry, M.⁸ Dykes, D.J.⁹ Harrison S.D., Jr.¹⁰ Ross, D.¹¹

15
- 0006985665
- (1998) Clin. Cancer Res. , vol.4 , pp. 3083-3088
- Siegel, D.¹ Franklin, W.A.² Ross, D.³

16
- 0034083154
- (2000) Invest. Ophthalmol. Visual Sci. , vol.41 , pp. 1617-1622
- Schelonka, L.P.¹ Siegel, D.² Wilson, M.W.³ Meininger, A.⁴ Ross, D.⁵

17
- 0016697619
- (1975) Arch. Biochem. Biophys. , vol.169 , pp. 560-567
- Hollander, P.¹ Ernster, L.²

18
- 0016281487
- (1974) J. Biol. Chem. , vol.549 , pp. 6416-6423
- Hosoda, S.¹ Nakamura, W.² Hayashi, K.³

19
- 0019442704
- (1981) J. Pharmacol. Exp. Ther. , vol.218 , pp. 416-420
- Hulse, M.¹ Feldman, S.² Bruckner, J.V.³

20
- 0025737686
- (1991) Free Radical Biol. Med. , vol.11 , pp. 77-80
- Preusch, P.C.¹ Siegel, D.² Gibson, N.W.³ Ross, D.⁴

21
- 0033566314
- (1999) Biochem. Pharmacol. , vol.58 , pp. 303-310
- Phillips, R.M.¹

22
- 0025893246
- (1991) Cancer Commun. , vol.3 , pp. 199-206
- Walton, M.I.¹ Smith, P.J.² Workman, P.³

23
- 0026602870
- (1992) Int. J. Radiat. Oncol. Biol. Phys. , vol.22 , pp. 649-653
- Bailey, S.M.¹ Suggett, N.² Walton, M.I.³ Workman, P.⁴

24
- 0032478053
- (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 545-548
- Beall, H.D.¹ Hudnott, A.R.² Winski, S.³ Siegel, D.⁴ Swann, E.⁵ Ross, D.⁶ Moody, C.J.⁷

25
- 7844226621
- (1998) J. Med. Chem. , vol.41 , pp. 4755-4766
- Beall, H.D.¹ Winski, S.² Swann, E.³ Hudnott, A.R.⁴ Cotterill, A.S.⁵ O'Sullivan, N.⁶ Green, S.J.⁷ Bien, R.⁸ Siegel, D.⁹ Ross, D.¹⁰ Moody, C.J.¹¹

26
- 0033533801
- (1999) J. Med. Chem. , vol.42 , pp. 4071-4080
- Phillips, R.M.¹ Naylor, M.A.² Jaffar, M.³ Doughty, S.W.⁴ Everett, S.A.⁵ Breen, A.G.⁶ Choudry, G.A.⁷ Stratford, I.J.⁸

27
- 0029068515
- (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 8846-8850
- Li, R.¹ Bianchet, M.A.² Talalay, P.³ Amzel, L.M.⁴

28
- 0034724218
- (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 3177-3182
- Faig, M.¹ Bianchet, M.A.² Talalay, P.³ Chen, S.⁴ Winski, S.⁵ Ross, D.⁶ Mario, A.L.⁷

29
- 0031026290
- (1997) J. Biol. Chem. , vol.272 , pp. 1437-1439
- Chen, S.¹ Knox, R.² Wu, K.³ Deng, P.S.K.⁴ Zhou, D.J.⁵ Bianchet, M.A.⁶ Amzel, L.M.⁷

30
- 0032741789
- (1999) J. Med. Chem. , vol.42 , pp. 4325-4330
- Skelly, J.V.¹ Sanderson, M.R.² Suter, D.A.³ Baumann, U.⁴ Read, M.A.⁵ Gregory, D.S.⁶ Bennett, M.⁷ Hobbs, S.M.⁸ Neidle, S.⁹

31
- 0034892645
- (2001) Structure , vol.9 , pp. 659-667
- Faig, M.¹ Bianchet, M.A.² Winski, S.³ Hargreaves, R.H.⁴ Moody, C.J.⁵ Ross, D.⁶ Amzel, L.M.⁷

32
- 0028243181
- (1994) Cancer Res. , vol.54 , pp. 3196-3201
- Beall, H.D.¹ Mulcahy, R.T.² Siegel, D.³ Traver, R.D.⁴ Gibson, N.W.⁵ Ross, D.⁶

33
- 0030805554
- (1997) Farmaco , vol.52 , pp. 271-279
- Moody, C.J.¹ Swann, E.²

34
- 0031059866
- (1996) Methods Enzymol. , pp. 276
- Otwinowski, Z.¹ Minor, W.²

35
- 0001835759
- (1993) Chem. Des. Automation News , vol.8 , pp. 31-37
- Allen, F.H.¹ Kennard, O.²

36
- 3543012707
- (1998) Acta Crystallogr., Sect. D: Biol. Crystallogr. , vol.54 , pp. 905-921
- Brunger, A.T.¹ Adams, P.D.² Clore, G.M.³ DeLano, W.L.⁴ Gros, P.⁵ Grosse-Kunstleve, R.W.⁶ Jiang, J.S.⁷ Kuszewski, J.⁸ Nilges, M.⁹ Pannu, N.S.¹⁰ Read, R.J.¹¹ Rice, L.M.¹² Simonson, T.¹³ Warren, G.L.¹⁴

37
- 84889120137
- (1991) Acta Crystallogr. A , vol.47 , pp. 110-119
- Jones, T.A.¹ Zou, J.Y.² Cowan, S.W.³ Kjeldgaard⁴

38
- 0001339532
- (1991) J. Appl. Crystallogr. , vol.24 , pp. 946-950
- Kraulis, P.¹

39
- 0030729838
- (1997) J. Mol. Graphics Modell , vol.15 , pp. 132-133
- Esnouf, R.M.¹

40
- 0030815133
- (1997) Methods Enzymol. , vol.277 , pp. 505-524
- Merrit, E.A.¹ Bacon²

41
- 0026319199
- (1991) Proteins , vol.11 , pp. 281-296
- Nicholls, A.¹ Sharp, K.A.² Honig, B.³

42
- 0003742069
- Department of Biochemistry and Molecular Biology, University College, London
- (1993) NACCESS Computer Program
- Hubbard, S.A.T.J.¹

43
- 0004006847
- CRC Press Inc., Boca Raton, FL
- (1988) Mechanism based enzyme inactivation: Chemistry and Enzymology , vol.1
- Silverman, R.B.¹

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