Cross-linking and sequence-specific alkylation of DNA by aziridinylquinones. 3. Effects of alkyl substituents

Journal of Medicinal Chemistry

Volumn 42, Issue 12, 1999, Pages 2245-2250

  Hargreaves, Robert H J ^a   O'Hare, C Caroline ^b   Hartley, John A ^b   Ross, David ^c   Butler, John ^a,d  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF SALFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 DIAZIRIDINYL 3 ETHYL 6 METHYL 1,4 BENZOQUINONE; 2,5 DIAZIRIDINYL 3 ISOPROPYL 6 METHYL 1,4 BENZOQUINONE; 2,5 DIAZIRIDINYL 3 METHYL 6 PROPYL 1,4 BENZOQUINONE; ALKYL GROUP; BENZOQUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DNA ALKYLATION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; REACTION TIME; REDUCTION; STRUCTURE ACTIVITY RELATION;

EID: 0033577984     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991007y     Document Type: Article

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