Constitutive activity modulation of human metabotropic glutamate 5a receptors in HEK293 cells: A role for key amino-terminal cysteine residues

British Journal of Pharmacology

Volumn 144, Issue 8, 2005, Pages 1118-1125

  Mühlemann, Andreas ^a   Diener, Catherine ^a   Fischer, Christophe ^a   Piussi, Jenny ^a   Stucki, Andy ^a   Porter, Richard H ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Constitutive activity; Glutamate; HmGlu5a cysteine mutants; MPEP; MTEP; Quisqualate; Whole cell binding

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3 [(2 METHYL 4 THIAZOLYL)ETHYNYL]PYRIDINE; CELL SURFACE PROTEIN; CYSTEINE; INOSITOL PHOSPHATE; METABOTROPIC RECEPTOR 5; MUTANT PROTEIN; QUISQUALIC ACID; SERINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL STRAIN HEK293; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CELL LINE; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 17844380255     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706152     Document Type: Article

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