메뉴 건너뛰기




Volumn 387, Issue 2, 2005, Pages 377-384

Shedding and γ-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43

Author keywords

secretase; Leukosialin; MUC1 mucin; Presenilin; Sialophorin

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; ENZYME INHIBITION; ENZYMES; GENES; MOLECULES;

EID: 17644421407     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041387     Document Type: Article
Times cited : (39)

References (47)
  • 2
    • 0026021936 scopus 로고
    • The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation
    • Cyster, J. G., Shotton, D. M. and Williams, A. F. (1991) The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation. EMBO J. 10, 893-902
    • (1991) EMBO J. , vol.10 , pp. 893-902
    • Cyster, J.G.1    Shotton, D.M.2    Williams, A.F.3
  • 3
    • 0024450712 scopus 로고
    • Phosphorylation of the major leukocyte surface sialoglycoprotein, leukosialin, is increased by phorbol 12-myristate 13-acetate
    • Piller, V., Piller, F. and Fukuda, M. (1989) Phosphorylation of the major leukocyte surface sialoglycoprotein, leukosialin, is increased by phorbol 12-myristate 13-acetate. J. Biol. Chem. 264, 18824-18831
    • (1989) J. Biol. Chem. , vol.264 , pp. 18824-18831
    • Piller, V.1    Piller, F.2    Fukuda, M.3
  • 4
    • 0029910821 scopus 로고    scopus 로고
    • CD43-specific activation of T cells induces association of CD43 to Fyn kinase
    • Pedraza-Alva, G., Merida, L. B., Burakoff, S. J. and Rosenstein, Y. (1996) CD43-specific activation of T cells induces association of CD43 to Fyn kinase. J. Biol. Chem. 271, 27564-27568
    • (1996) J. Biol. Chem. , vol.271 , pp. 27564-27568
    • Pedraza-Alva, G.1    Merida, L.B.2    Burakoff, S.J.3    Rosenstein, Y.4
  • 6
    • 0035652354 scopus 로고    scopus 로고
    • Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin
    • Delon, J., Kaibuchi, K. and Germain, R. N. (2001) Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity 15, 691-701
    • (2001) Immunity , vol.15 , pp. 691-701
    • Delon, J.1    Kaibuchi, K.2    Germain, R.N.3
  • 7
    • 0031764539 scopus 로고    scopus 로고
    • The Roman god Janus: A paradigm for the function of CD43
    • Ostberg, J. R., Barth, R. K. and Frelinger, J. G. (1998) The Roman god Janus: a paradigm for the function of CD43. Immunol. Today 19, 546-550
    • (1998) Immunol. Today , vol.19 , pp. 546-550
    • Ostberg, J.R.1    Barth, R.K.2    Frelinger, J.G.3
  • 8
    • 0032486271 scopus 로고    scopus 로고
    • T cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activation
    • Pedraza-Alva, G., Merida, L. B., Burakoff, S. J. and Rosenstein, Y. (1998) T cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activation. J. Biol. Chem. 273, 14218-14224
    • (1998) J. Biol. Chem. , vol.273 , pp. 14218-14224
    • Pedraza-Alva, G.1    Merida, L.B.2    Burakoff, S.J.3    Rosenstein, Y.4
  • 11
    • 0028888531 scopus 로고
    • Dysregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survival
    • Dragone, L. L., Barth, R. K., Sitar, K. L., Disbrow, G. L. and Frelinger, J. G. (1995) Dysregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survival. Proc. Natl. Acad. Sci. U.S.A. 92, 626-630
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 626-630
    • Dragone, L.L.1    Barth, R.K.2    Sitar, K.L.3    Disbrow, G.L.4    Frelinger, J.G.5
  • 12
    • 0029856634 scopus 로고    scopus 로고
    • CD43 expression in a B cell lymphoma, WEHI 231, reduces susceptibility to G1 arrest and extends survival in culture upon serum depletion
    • Misawa, Y., Nagaoka, H., Kimoto, H., Ishii, Y., Kitamura, K., Tsunetsugu-Yokota, Y., Shibuya, M. and Takemori, T. (1996) CD43 expression in a B cell lymphoma, WEHI 231, reduces susceptibility to G1 arrest and extends survival in culture upon serum depletion. Eur. J. Immunol. 26, 2573-2581
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2573-2581
    • Misawa, Y.1    Nagaoka, H.2    Kimoto, H.3    Ishii, Y.4    Kitamura, K.5    Tsunetsugu-Yokota, Y.6    Shibuya, M.7    Takemori, T.8
  • 13
    • 0037040868 scopus 로고    scopus 로고
    • Molecular mechanisms involved in cd43-mediated apoptosis of TF-1 cells
    • Cermak, L., Simova, S., Pintzas, A., Horejsi, V. and Andera, L. (2002) Molecular mechanisms involved in cd43-mediated apoptosis of TF-1 cells. J. Biol. Chem. 277, 7955-7961
    • (2002) J. Biol. Chem. , vol.277 , pp. 7955-7961
    • Cermak, L.1    Simova, S.2    Pintzas, A.3    Horejsi, V.4    Andera, L.5
  • 14
    • 0029067525 scopus 로고
    • Expression of the leukocyte-associated sialoglycoprotein CD43 by a colon carcinoma cell line
    • Baeckstrom, D., Zhang, K., Asker, N., Ruetschi, U., Ek, M. and Hansson, G. C. (1995) Expression of the leukocyte-associated sialoglycoprotein CD43 by a colon carcinoma cell line. J. Biol. Chem. 270, 13688-13692
    • (1995) J. Biol. Chem. , vol.270 , pp. 13688-13692
    • Baeckstrom, D.1    Zhang, K.2    Asker, N.3    Ruetschi, U.4    Ek, M.5    Hansson, G.C.6
  • 15
    • 0030015134 scopus 로고    scopus 로고
    • Specific monoclonal antibodies against leukocyte-restricted cell surface molecule CD43 react with nonhematopoietic tumor cells
    • Santamaria, M., Lopez-Beltran, A., Toro, M., Pena, J. and Molina, I. J. (1996) Specific monoclonal antibodies against leukocyte-restricted cell surface molecule CD43 react with nonhematopoietic tumor cells. Cancer Res. 56, 3526-3529
    • (1996) Cancer Res. , vol.56 , pp. 3526-3529
    • Santamaria, M.1    Lopez-Beltran, A.2    Toro, M.3    Pena, J.4    Molina, I.J.5
  • 17
    • 0031577561 scopus 로고    scopus 로고
    • Colon adenoma and cancer cells aberrantly express the leukocyte-associated sialoglycoprotein CD43. Biochem
    • Sikut, R., Nilsson, O., Baeckstrom, D. and Hansson, G. C. (1997) Colon adenoma and cancer cells aberrantly express the leukocyte-associated sialoglycoprotein CD43. Biochem. Biophys. Res. Commun. 238, 612-616
    • (1997) Biophys. Res. Commun. , vol.238 , pp. 612-616
    • Sikut, R.1    Nilsson, O.2    Baeckstrom, D.3    Hansson, G.C.4
  • 20
    • 0032574993 scopus 로고    scopus 로고
    • Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
    • Schroeter, E. H., Kisslinger, J. A. and Kopan, R. (1998) Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature (London) 393, 382-386
    • (1998) Nature (London) , vol.393 , pp. 382-386
    • Schroeter, E.H.1    Kisslinger, J.A.2    Kopan, R.3
  • 21
    • 0037431082 scopus 로고    scopus 로고
    • Aph-1, Pen-2, and Nicastrin with presenilin generate an active gamma-secretase complex
    • De Strooper, B. (2003) Aph-1, Pen-2, and Nicastrin with presenilin generate an active gamma-secretase complex. Neuron 38, 9-12
    • (2003) Neuron , vol.38 , pp. 9-12
    • De Strooper, B.1
  • 22
    • 0003356476 scopus 로고    scopus 로고
    • Role of the ErbB-4 carboxyl terminus in gamma-secretase cleavage
    • Ni, C. Y., Yuan, H. and Carpenter, G. (2003) Role of the ErbB-4 carboxyl terminus in gamma-secretase cleavage. J. Biol. Chem. 278, 4561-4565
    • (2003) J. Biol. Chem. , vol.278 , pp. 4561-4565
    • Ni, C.Y.1    Yuan, H.2    Carpenter, G.3
  • 23
    • 18344380083 scopus 로고    scopus 로고
    • A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
    • Marambaud, P., Shioi, J., Serban, G., Georgakopoulos, A., Sarner, S., Nagy, V., Baki, L., Wen, P., Efthimiopoulos, S., Shao, Z. et al. (2002) A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J. 21, 1948-1956
    • (2002) EMBO J. , vol.21 , pp. 1948-1956
    • Marambaud, P.1    Shioi, J.2    Serban, G.3    Georgakopoulos, A.4    Sarner, S.5    Nagy, V.6    Baki, L.7    Wen, P.8    Efthimiopoulos, S.9    Shao, Z.10
  • 24
    • 0347785491 scopus 로고    scopus 로고
    • Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide
    • Lammich, S., Okochi, M., Takeda, M., Kaether, C., Capell, A., Zimmer, A. K., Edbauer, D., Walter, J., Steiner, H. and Haass, C. (2002) Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide. J. Biol. Chem. 277, 44754-44759
    • (2002) J. Biol. Chem. , vol.277 , pp. 44754-44759
    • Lammich, S.1    Okochi, M.2    Takeda, M.3    Kaether, C.4    Capell, A.5    Zimmer, A.K.6    Edbauer, D.7    Walter, J.8    Steiner, H.9    Haass, C.10
  • 26
    • 0033615580 scopus 로고    scopus 로고
    • The presenilins in Alzheimer's disease - Proteolysis holds the key
    • Haass, C. and De Strooper, B. (1999) The presenilins in Alzheimer's disease - proteolysis holds the key. Science 286, 916-919
    • (1999) Science , vol.286 , pp. 916-919
    • Haass, C.1    De Strooper, B.2
  • 27
    • 0037118248 scopus 로고    scopus 로고
    • A RIP tide in neuronal signal transduction
    • Ebinu, J. O. and Yankner, B. A. (2002) A RIP tide in neuronal signal transduction. Neuron 34, 499-502
    • (2002) Neuron , vol.34 , pp. 499-502
    • Ebinu, J.O.1    Yankner, B.A.2
  • 28
    • 0242300624 scopus 로고    scopus 로고
    • Games played by rogue proteins in prion disorders and Alzheimer's disease
    • Aguzzi, A. and Haass, C. (2003) Games played by rogue proteins in prion disorders and Alzheimer's disease. Science 302, 814-818
    • (2003) Science , vol.302 , pp. 814-818
    • Aguzzi, A.1    Haass, C.2
  • 29
    • 0034681260 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
    • Brown, M. S., Ye, J., Rawson, R. B. and Goldstein, J. L. (2000) Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 100, 391-398
    • (2000) Cell , vol.100 , pp. 391-398
    • Brown, M.S.1    Ye, J.2    Rawson, R.B.3    Goldstein, J.L.4
  • 30
    • 0033535553 scopus 로고    scopus 로고
    • Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
    • Wolfe, M. S., Xia, W., Ostaszewski, B. L., Diehl, T. S., Kimberly, W. T. and Selkoe, D. J. (1999) Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature (London) 398, 513-517
    • (1999) Nature (London) , vol.398 , pp. 513-517
    • Wolfe, M.S.1    Xia, W.2    Ostaszewski, B.L.3    Diehl, T.S.4    Kimberly, W.T.5    Selkoe, D.J.6
  • 31
    • 0035918199 scopus 로고    scopus 로고
    • Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
    • Schroeder, J. A., Thompson, M. C., Gardner, M. M. and Gendler, S. J. (2001) Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J. Biol. Chem. 276, 13057-13064
    • (2001) J. Biol. Chem. , vol.276 , pp. 13057-13064
    • Schroeder, J.A.1    Thompson, M.C.2    Gardner, M.M.3    Gendler, S.J.4
  • 32
    • 0034254585 scopus 로고    scopus 로고
    • L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity
    • Shearman, M. S., Beher, D., Clarke, E. E., Lewis, H. D., Harrison, T., Hunt, P., Nadin, A., Smith, A. L., Stevenson, G. and Castro, J. L. (2000) L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity. Biochemistry 39, 8698-9704
    • (2000) Biochemistry , vol.39 , pp. 8698-9704
    • Shearman, M.S.1    Beher, D.2    Clarke, E.E.3    Lewis, H.D.4    Harrison, T.5    Hunt, P.6    Nadin, A.7    Smith, A.L.8    Stevenson, G.9    Castro, J.L.10
  • 33
    • 0037134505 scopus 로고    scopus 로고
    • Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)
    • Edbauer, D., Willem, M., Lammich, S., Steiner, H. and Haass, C. (2002) Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD). J. Biol. Chem. 277, 13389-13393
    • (2002) J. Biol. Chem. , vol.277 , pp. 13389-13393
    • Edbauer, D.1    Willem, M.2    Lammich, S.3    Steiner, H.4    Haass, C.5
  • 34
    • 0029959827 scopus 로고    scopus 로고
    • Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells
    • Brown, T. J., Shuford, W. W., Wang, W. C., Nadler, S. G., Bailey, T. S., Marquardt, H. and Mittler, R. S. (1996) Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells. J. Biol. Chem. 271, 27686-27695
    • (1996) J. Biol. Chem. , vol.271 , pp. 27686-27695
    • Brown, T.J.1    Shuford, W.W.2    Wang, W.C.3    Nadler, S.G.4    Bailey, T.S.5    Marquardt, H.6    Mittler, R.S.7
  • 35
    • 0023019597 scopus 로고
    • Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines
    • Carlsson, S. R., Sasaki, H. and Fukuda, M. (1986) Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines. J. Biol. Chem. 261, 12787-12795
    • (1986) J. Biol. Chem. , vol.261 , pp. 12787-12795
    • Carlsson, S.R.1    Sasaki, H.2    Fukuda, M.3
  • 36
    • 0028265826 scopus 로고
    • Metalloprotease and serine protease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes. Induction of cleavage of L-selectin via CD16
    • Bazil, V. and Strominger, J. L. (1994) Metalloprotease and serine protease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes. Induction of cleavage of L-selectin via CD16. J. Immunol. 152, 1314-1322
    • (1994) J. Immunol. , vol.152 , pp. 1314-1322
    • Bazil, V.1    Strominger, J.L.2
  • 37
    • 0028258922 scopus 로고
    • Two proteolytic pathways for down-regulation of the barrier molecule CD43 of human neutrophils
    • Remold-O'Donnell, E. and Parent, D. (1994) Two proteolytic pathways for down-regulation of the barrier molecule CD43 of human neutrophils. J. Immunol. 152, 3595-3605
    • (1994) J. Immunol. , vol.152 , pp. 3595-3605
    • Remold-O'Donnell, E.1    Parent, D.2
  • 38
    • 0034568802 scopus 로고    scopus 로고
    • Intramembrane proteolysis by presenilins
    • Steiner, H. and Haass, C. (2000) Intramembrane proteolysis by presenilins. Nat. Rev. Mol. Cell Biol. 1, 217-224
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 217-224
    • Steiner, H.1    Haass, C.2
  • 40
    • 0037474312 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding
    • Thathiah, A., Blobel, C. P. and Carson, D. D. (2003) Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding. J. Biol. Chem. 278, 3386-3394
    • (2003) J. Biol. Chem. , vol.278 , pp. 3386-3394
    • Thathiah, A.1    Blobel, C.P.2    Carson, D.D.3
  • 41
    • 0026721943 scopus 로고
    • Beta-amyloid precursor protein cleavage by a membrane-bound protease
    • Sisodia, S. S. (1992) Beta-amyloid precursor protein cleavage by a membrane-bound protease. Proc. Natl. Acad. Sci. U.S.A. 89, 6075-6079
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 6075-6079
    • Sisodia, S.S.1
  • 42
    • 0036677928 scopus 로고    scopus 로고
    • Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: Association with Fe65 and translocation to the nucleus
    • Kinoshita, A., Whelan, C. M., Smith, C. J., Berezovska, O. and Hyman, B. T. (2002) Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus. J. Neurochem. 82, 839-847
    • (2002) J. Neurochem. , vol.82 , pp. 839-847
    • Kinoshita, A.1    Whelan, C.M.2    Smith, C.J.3    Berezovska, O.4    Hyman, B.T.5
  • 43
    • 0035909901 scopus 로고    scopus 로고
    • The gamma-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus
    • Gao, Y. and Pimplikar, S. W. (2001) The gamma-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus. Proc. Natl. Acad. Sci. U.S.A. 98, 14979-14984
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 14979-14984
    • Gao, Y.1    Pimplikar, S.W.2
  • 44
    • 0034049944 scopus 로고    scopus 로고
    • Proteolytic processing and cell biological functions of the amyloid precursor protein
    • De Strooper, B. and Annaert, W. (2000) Proteolytic processing and cell biological functions of the amyloid precursor protein. J. Cell Sci. 113, 1857-1870
    • (2000) J. Cell Sci. , vol.113 , pp. 1857-1870
    • De Strooper, B.1    Annaert, W.2
  • 45
    • 0034774969 scopus 로고    scopus 로고
    • Presenilin-dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
    • Sastre, M., Steiner, H., Fuchs, K., Capell, A., Multhaup, G., Condron, M. M., Teplow, D. B. and Haass, C. (2001) Presenilin-dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch. EMBO Rep. 2, 835-841
    • (2001) EMBO Rep. , vol.2 , pp. 835-841
    • Sastre, M.1    Steiner, H.2    Fuchs, K.3    Capell, A.4    Multhaup, G.5    Condron, M.M.6    Teplow, D.B.7    Haass, C.8
  • 46
    • 0041850346 scopus 로고    scopus 로고
    • Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
    • Li, Y., Liu, D., Chen, D., Kharbanda, S. and Kufe, D. (2003) Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22, 6107-6110
    • (2003) Oncogene , vol.22 , pp. 6107-6110
    • Li, Y.1    Liu, D.2    Chen, D.3    Kharbanda, S.4    Kufe, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.