In situ evaluation of drug-loaded microspheres on a mucosal surface under dynamic test conditions

International Journal of Pharmaceutics

Volumn 276, Issue 1-2, 2004, Pages 51-58

  Kockisch, Sandra ^a,d   Rees, Gareth D ^b   Young, Simon A ^a   Tsibouklis, John ^a   Smart, John D ^c  

^a UNIVERSITY OF PORTSMOUTH   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF BRIGHTON   (United Kingdom)

^d LILLY DEUTSCHLAND GMBH   (Germany)

Author keywords

Bioadhesion; Chitosan; Maleic anhydride copolymers; Mucoadhesion; Oral cavity; Poly(acrylic acid)

Indexed keywords

CARBOMER; CHITOSAN; GANTREZ COPOLYMER; MICROSPHERE; POLYCARBOPHIL;

ANIMAL TISSUE; ARTICLE; CAMERA; CHEEK MUCOSA; CONTROLLED STUDY; DRUG COATING; ESOPHAGUS MUSCLE; EVALUATION; HUMIDITY; HYDROPHILICITY; IMAGE ANALYSIS; MOLECULAR DYNAMICS; MOUTH CAVITY; NONHUMAN; PRIORITY JOURNAL; SALIVATION; SIMULATION; SUSTAINED DRUG RELEASE; TEMPERATURE;

ANIMALS; BIOCOMPATIBLE MATERIALS; CHEMISTRY, PHARMACEUTICAL; CHITIN; CHITOSAN; CONTRAST MEDIA; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; ESOPHAGUS; FLUORESCEIN; MALEATES; MICROSPHERES; MOUTH MUCOSA; POLYVINYLS; PROTEASE INHIBITORS; SWINE; TISSUE ADHESIVES;

EID: 2142808711     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.02.020     Document Type: Article

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