메뉴 건너뛰기




Volumn 6, Issue 4, 2005, Pages 427-434

Muraglitazar (Bristol-Myers Squibb/Merck)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; ACYL COENZYME A; ADIPONECTIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; APOLIPOPROTEIN C3; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CORTICOSTERONE; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; FATTY ACID; FUROSEMIDE; GLUCOCORTICOID; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MURAGLITAZAR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; SULFONYLUREA; TRIACYLGLYCEROL; UNINDEXED DRUG; VERY LOW DENSITY LIPOPROTEIN;

EID: 17644363341     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (20)

References (64)
  • 2
    • 0035431321 scopus 로고    scopus 로고
    • Structure of the PPARα and -γ ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family
    • 442540
    • 442540 Structure of the PPARα and -γ ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family. Cronet P, Petersen JF, Folmer R, Blomberg N, Sjoblom K, Karlsson U, Lindstedt EL, Bamberg K STRUCTURE 2001 9 8 699-706
    • (2001) Structure , vol.9 , Issue.8 , pp. 699-706
    • Cronet, P.1    Petersen, J.F.2    Folmer, R.3    Blomberg, N.4    Sjoblom, K.5    Karlsson, U.6    Lindstedt, E.L.7    Bamberg, K.8
  • 3
    • 0141488815 scopus 로고    scopus 로고
    • BMS-298585 is a novel, uniquely balanced dual activator of peroxisome proliferator activated receptors (PPAR) α and γ, with an excellent ADME profile
    • 454098 A381-PO
    • 454098 BMS-298585 is a novel, uniquely balanced dual activator of peroxisome proliferator activated receptors (PPAR) α and γ, with an excellent ADME profile. Cheng PT, Chandrasena G, Chen S, Devasthale P, Hariharan N DIABETES 2002 51 2 A381-PO
    • (2002) Diabetes , vol.51 , Issue.2
    • Cheng, P.T.1    Chandrasena, G.2    Chen, S.3    Devasthale, P.4    Hariharan, N.5
  • 4
    • 2542604395 scopus 로고    scopus 로고
    • BMS-298585, a novel uniquely balanced dual activator of PPAR α and γ, shows robust glucose and lipid lowering effects in genetic and diet induced diabetic and hyperlipidemic mouse models
    • 454180 A405-P
    • 454180 BMS-298585, a novel uniquely balanced dual activator of PPAR α and γ, shows robust glucose and lipid lowering effects in genetic and diet induced diabetic and hyperlipidemic mouse models. Hariharan N, Chen S, Cheng P, Chu C, Devasthale P, Farrelly D, Harrity T, Selan F DIABETES 2002 51 2 A405-P
    • (2002) Diabetes , vol.51 , Issue.2
    • Hariharan, N.1    Chen, S.2    Cheng, P.3    Chu, C.4    Devasthale, P.5    Farrelly, D.6    Harrity, T.7    Selan, F.8
  • 5
    • 0842325532 scopus 로고    scopus 로고
    • BMS-298585, a novel uniquely balanced dual activator of PPAR α and γ, shows robust lipid and glucose lowering effects in high fat diet induced hyperlipidemic insulin resistant hamsters
    • 454181 A407-P
    • 454181 BMS-298585, a novel uniquely balanced dual activator of PPAR α and γ, shows robust lipid and glucose lowering effects in high fat diet induced hyperlipidemic insulin resistant hamsters. Harrity T, Hariharan N, Chang P, Selan F, Kunselman L, Chen S, Devasthale P, Chu C, Farrelly D DIABETES 2002 51 2 A407-P
    • (2002) Diabetes , vol.51 , Issue.2
    • Harrity, T.1    Hariharan, N.2    Chang, P.3    Selan, F.4    Kunselman, L.5    Chen, S.6    Devasthale, P.7    Chu, C.8    Farrelly, D.9
  • 7
    • 17644416301 scopus 로고    scopus 로고
    • BMS-298585, a novel uniquely balanced duel agonist of PPAR α and γ, lowers lipid in diet induced diabetic and hyperlipidemic mice and hamsters
    • 463529
    • 463529 BMS-298585, a novel uniquely balanced duel agonist of PPAR α and γ, lowers lipid in diet induced diabetic and hyperlipidemic mice and hamsters. Hariharan N, Harrity T, Kunselman L, Farrelly D, Sasseville V, Cheng PT DIABETOLOGIA 2002 45 Suppl 2 A234
    • (2002) Diabetologia , vol.45 , Issue.SUPPL. 2
    • Hariharan, N.1    Harrity, T.2    Kunselman, L.3    Farrelly, D.4    Sasseville, V.5    Cheng, P.T.6
  • 9
    • 17644382536 scopus 로고    scopus 로고
    • Novo Nordisk to move forward on development of Dr Reddy's balaglitazone - DRF 2593
    • 478168 Dr Reddy's Laboratories Ltd PRESS RELEASE February 06
    • 478168 Novo Nordisk to move forward on development of Dr Reddy's balaglitazone - DRF 2593. Dr Reddy's Laboratories Ltd PRESS RELEASE 2003 February 06
    • (2003)
  • 10
    • 17644379814 scopus 로고    scopus 로고
    • Novo Nordisk A/S (NYSE: NVO) financial statement for 2002
    • 478217 Novo Nordisk A/S PRESS RELEASE February 06
    • 478217 Novo Nordisk A/S (NYSE: NVO) financial statement for 2002. Novo Nordisk A/S PRESS RELEASE 2003 February 06
    • (2003)
  • 13
    • 17644384716 scopus 로고    scopus 로고
    • 486672 Bristol Myers Squibb Co ANNUAL REPORT March 25
    • 486672 Annual Report 2002: Bristol-Myers Squibb. Bristol Myers Squibb Co ANNUAL REPORT 2003 March 25
    • (2003) Annual Report 2002: Bristol-Myers Squibb
  • 14
    • 17644414846 scopus 로고    scopus 로고
    • Merck discontinues development of MK-767 for diabetes
    • 514245 Merck & Co Inc PRESS RELEASE November 20
    • 514245 Merck discontinues development of MK-767 for diabetes. Merck & Co Inc PRESS RELEASE 2003 November 20
    • (2003)
  • 15
    • 17644363232 scopus 로고    scopus 로고
    • Bristol-Myers Squibb: Development compounds
    • 525071 Bristol Myers Squibb Co COMPANY WORLD WIDE WEB SITE February 12
    • 525071 Bristol-Myers Squibb: Development compounds. Bristol Myers Squibb Co COMPANY WORLD WIDE WEB SITE 2004 February 12
    • (2004)
  • 16
    • 17644377148 scopus 로고    scopus 로고
    • Bristol-Myers Squibb and Merck announce global development and commercialization alliance for muraglitazar, a novel compound for diabetes
    • 535305 Bristol-Myers Squibb Company PRESS RELEASE April 28
    • 535305 Bristol-Myers Squibb and Merck announce global development and commercialization alliance for muraglitazar, a novel compound for diabetes. Bristol-Myers Squibb Company PRESS RELEASE 2004 April 28
    • (2004)
  • 17
    • 17644371242 scopus 로고    scopus 로고
    • Merck & Co enters alliance for BMS's diabetes drug muraglitazar
    • 535435 Merck & Co Inc PRESS RELEASE April 28
    • 535435 Merck & Co enters alliance for BMS's diabetes drug muraglitazar. Merck & Co Inc PRESS RELEASE 2004 April 28
    • (2004)
  • 18
    • 17644362904 scopus 로고    scopus 로고
    • Muraglitazar, a novel non-TZD dual PPAR α/γ agonist, improves metabolic abnormalities in obese, severely diabetic db/db mice
    • 541486 Abs 134-OR
    • 541486 Muraglitazar, a novel non-TZD dual PPAR α/γ agonist, improves metabolic abnormalities in obese, severely diabetic db/db mice. Harrity T, Chu C, Kunselman L, Ponticiello R, Cap M, Cheng P, Hariharan N DIABETES 2004 53 Abs 134-OR
    • (2004) Diabetes , vol.53
    • Harrity, T.1    Chu, C.2    Kunselman, L.3    Ponticiello, R.4    Cap, M.5    Cheng, P.6    Hariharan, N.7
  • 19
    • 17744363287 scopus 로고    scopus 로고
    • Glucose lowering effects of multiple dose administration of muraglitazar (BMS-298585), a novel PPAR α/γ dual agonist, in type 2 diabetic patients
    • 541493 Abs 138-OR
    • 541493 Glucose lowering effects of multiple dose administration of muraglitazar (BMS-298585), a novel PPAR α /γ dual agonist, in type 2 diabetic patients. Mosqueda-Garcia R, Frost CE, Swaminathan A, Raymond R, Nepal S, Reeves R, Gregg R DIABETES 2004 53 Abs 138-OR
    • (2004) Diabetes , vol.53
    • Mosqueda-Garcia, R.1    Frost, C.E.2    Swaminathan, A.3    Raymond, R.4    Nepal, S.5    Reeves, R.6    Gregg, R.7
  • 20
    • 17644415932 scopus 로고    scopus 로고
    • Muraglitazar, a novel non-TZD PPAR α/γ dual agonist, regulates genes involved in reverse cholesterol transport, stimulates cholesterol efflux, and reduces MCP1 secretion in human THP1 macrophage cells
    • 542286 Abs 640-P
    • 542286 Muraglitazar, a novel non-TZD PPAR α/γ dual agonist, regulates genes involved in reverse cholesterol transport, stimulates cholesterol efflux, and reduces MCP1 secretion in human THP1 macrophage cells. Zhou M, Peters A, Cao G, Farrelly D, Harrity T, Cheng P, Hariharan N DIABETES 2004 53 Abs 640-P
    • (2004) Diabetes , vol.53
    • Zhou, M.1    Peters, A.2    Cao, G.3    Farrelly, D.4    Harrity, T.5    Cheng, P.6    Hariharan, N.7
  • 21
    • 17644377149 scopus 로고    scopus 로고
    • American Diabetes Association - 64th Scientific Sessions (Part III) - Overnight Report
    • 542450 Orlando, FL, USA. Mazucco R IDDB MEETING REPORT June 4-8
    • 542450 American Diabetes Association - 64th Scientific Sessions (Part III) - Overnight Report, Orlando, FL, USA. Mazucco R IDDB MEETING REPORT 2004 June 4-8
    • (2004)
  • 22
    • 14744291446 scopus 로고    scopus 로고
    • Pharmacokinetics of single doses of the novel PPAR α/γ dual agonist muraglitazar (BMS-298585) in healthy human subjects
    • 542466 Abs 618-P
    • 542466 Pharmacokinetics of single doses of the novel PPAR α/γ dual agonist muraglitazar (BMS-298585) in healthy human subjects. Swaminathan A, Frost CE, Raymond R, Reeves R, Mosqueda-Garcia R DIABETES 2004 53 Abs 618-P
    • (2004) Diabetes , vol.53
    • Swaminathan, A.1    Frost, C.E.2    Raymond, R.3    Reeves, R.4    Mosqueda-Garcia, R.5
  • 23
    • 17644369153 scopus 로고    scopus 로고
    • Lipid lowering effects of multiple dose administration of muraglitazar (BMS-298585), a novel PPAR α/γ dual agonist, in type 2 diabetic patients
    • 544834 Abs 1988-PO
    • 544834 Lipid lowering effects of multiple dose administration of muraglitazar (BMS-298585), a novel PPAR α/γ dual agonist, in type 2 diabetic patients. Frost CE, Swaminathan A, Raymond R, Nepal S, Gregg R, Reeves R, Mosqueda-Garcia R DIABETES 2004 53 Abs 1988-PO
    • (2004) Diabetes , vol.53
    • Frost, C.E.1    Swaminathan, A.2    Raymond, R.3    Nepal, S.4    Gregg, R.5    Reeves, R.6    Mosqueda-Garcia, R.7
  • 24
    • 17644394483 scopus 로고    scopus 로고
    • BMS provides R&D update
    • 571507 Bristol-Myers Squibb Co PRESS RELEASE November 17
    • 571507 BMS provides R&D update. Bristol-Myers Squibb Co PRESS RELEASE 2004 November 17
    • (2004)
  • 25
    • 17644425185 scopus 로고    scopus 로고
    • Bristol-Myers Squibb R&D review
    • 572056 Bristol-Myers Squibb Co COMPANY PRESENTATION November 17
    • 572056 Bristol-Myers Squibb R&D review. Bristol-Myers Squibb Co COMPANY PRESENTATION 2004 November 17
    • (2004)
  • 26
    • 17644364947 scopus 로고    scopus 로고
    • BMS submits muraglitazar NDA for type 2 diabetes
    • 577532 Bristol-Myers Squibb Co PRESS RELEASE December 23
    • 577532 BMS submits muraglitazar NDA for type 2 diabetes. Bristol-Myers Squibb Co PRESS RELEASE 2004 December 23
    • (2004)
  • 27
    • 3843079807 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α/γ dual agonists for the treatment of type 2 diabetes
    • 579204
    • 579204 Peroxisome proliferator-activated receptor α/γ dual agonists for the treatment of type 2 diabetes. Henke BR J MED CHEM 2004 47 17 4118-4127
    • (2004) J. Med. Chem. , vol.47 , Issue.17 , pp. 4118-4127
    • Henke, B.R.1
  • 28
    • 2642546685 scopus 로고    scopus 로고
    • Future targets in the treatment of type 2 diabetes
    • 579206
    • 579206 Future targets in the treatment of type 2 diabetes. Stingl H, Roden M WIEN KLIN WOCHENSCHR 2004 116 7-8 217-229.
    • (2004) Wien. Klin. Wochenschr. , vol.116 , Issue.7-8 , pp. 217-229
    • Stingl, H.1    Roden, M.2
  • 29
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • 579210
    • 579210 PPARs and the complex journey to obesity. Evans RM, Barish GD, Wang Y-X NAT MED 2004 10 4 355-361
    • (2004) Nat. Med. , vol.10 , Issue.4 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.-X.3
  • 31
    • 0142056850 scopus 로고    scopus 로고
    • Therapeutic significance of peroxisome proliferator-activated receptor modulators in diabetes
    • 579216
    • 579216 Therapeutic significance of peroxisome proliferator-activated receptor modulators in diabetes. Ram VJ DRUGS TODAY 2003 39 8 609-632
    • (2003) Drugs Today , vol.39 , Issue.8 , pp. 609-632
    • Ram, V.J.1
  • 32
    • 0842263981 scopus 로고    scopus 로고
    • The biology of peroxisome proliferator-activated receptors. Relationship with lipid metabolism and insulin sensitivity
    • 579218
    • 579218 The biology of peroxisome proliferator-activated receptors. Relationship with lipid metabolism and insulin sensitivity. Ferre P DIABETES 2004 53 Suppl 1 S43-S50
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Ferre, P.1
  • 33
    • 4744363428 scopus 로고    scopus 로고
    • Pharmaceutical approaches to the treatment of obesity
    • 579221
    • 579221 Pharmaceutical approaches to the treatment of obesity. Jandacek, RJ, Woods SC DRUG DISC TODAY 2004 9 20 874-880
    • (2004) Drug Disc. Today , vol.9 , Issue.20 , pp. 874-880
    • Jandacek, R.J.1    Woods, S.C.2
  • 34
    • 0842285629 scopus 로고    scopus 로고
    • Potential role of peroxisome proliferator-activated receptor-α in the modulation of glucose-stimulated insulin secretion
    • 579457
    • 579457 Potential role of peroxisome proliferator-activated receptor-α in the modulation of glucose-stimulated insulin secretion. Sugden MC, Holness MJ DIABETES 2004 53 Suppl 1 S71-S81
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Sugden, M.C.1    Holness, M.J.2
  • 35
    • 2542491213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ in diabetes and metabolism
    • 579458
    • 579458 Peroxisome proliferator-activated receptor γ in diabetes and metabolism. Rangwala SM, Lazar MA TRENDS PHARMACOL SCI 2004 25 6331-336
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 6331-6336
    • Rangwala, S.M.1    Lazar, M.A.2
  • 38
    • 1842454746 scopus 로고    scopus 로고
    • Clinical interest of PPARs ligands: Particular benefit in type 2 diabetes and metabolic syndrome
    • 579463
    • 579463 Clinical interest of PPARs ligands: Particular benefit in type 2 diabetes and metabolic syndrome. Verges B DIABETES METAB 2004 30 1 7-12
    • (2004) Diabetes Metab. , vol.30 , Issue.1 , pp. 7-12
    • Verges, B.1
  • 39
    • 17644419879 scopus 로고    scopus 로고
    • Synthesis of novel antidiabetic polymer containing thiazolidinedione and L-ascorbic acid
    • 579464
    • 579464 Synthesis of novel antidiabetic polymer containing thiazolidinedione and L-ascorbic acid. Jeon R, Lee SM DRUGS FUTURE 2004 29 Suppl A P250
    • (2004) Drugs Future , vol.29 , Issue.SUPPL. A
    • Jeon, R.1    Lee, S.M.2
  • 41
    • 17644382535 scopus 로고    scopus 로고
    • Synthesis and crystal structure of a PPAR pan agonist that delivers glycemic control and improved lipid profiles without weight gain
    • 579466
    • 579466 Synthesis and crystal structure of a PPAR pan agonist that delivers glycemic control and improved lipid profiles without weight gain. Sternbach DD, Rafferty S, Cadilla R, Lambert M, Xu E, Montana V, Oliver W Jr DRUGS FUTURE 2004 29 Suppl A 044
    • (2004) Drugs Future , vol.29 , Issue.SUPPL. A , pp. 044
    • Sternbach, D.D.1    Rafferty, S.2    Cadilla, R.3    Lambert, M.4    Xu, E.5    Montana, V.6    Oliver Jr., W.7
  • 43
    • 2342639558 scopus 로고    scopus 로고
    • Diabetes, lipids, and adipocyte secretagogues
    • 579468
    • 579468 Diabetes, lipids, and adipocyte secretagogues. Faraj M, Lu HL, Cianflone K BIOCHEM CELL BIOL 2004 82 1 170-190
    • (2004) Biochem. Cell Biol. , vol.82 , Issue.1 , pp. 170-190
    • Faraj, M.1    Lu, H.L.2    Cianflone, K.3
  • 45
    • 17644407937 scopus 로고    scopus 로고
    • Signals adapting the β cells to changes in insulin sensitivity
    • 579473
    • 579473 Signals adapting the β cells to changes in insulin sensitivity. Ahren B, Pacini G INT CONGR SER EXCERPTA MED 2003 1253 105-113
    • (2003) Int. Congr. Ser. Excerpta Med. , vol.1253 , pp. 105-113
    • Ahren, B.1    Pacini, G.2
  • 47
    • 1642446053 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ. Too much of a good thing causes harm
    • 579480
    • 579480 Peroxisome proliferator-activated receptor-γ. Too much of a good thing causes harm. Cock T-A, Houten SM, Auwerx J EMBO REPS 2004 5 2 142-147
    • (2004) Embo. Reps. , vol.5 , Issue.2 , pp. 142-147
    • Cock, T.-A.1    Houten, S.M.2    Auwerx, J.3
  • 48
    • 0038148948 scopus 로고    scopus 로고
    • Roles of peroxisome proliferator-activated receptors δ and γ in myoblast transdifferentiation
    • 579481
    • 579481 Roles of peroxisome proliferator-activated receptors δ and γ in myoblast transdifferentiation. Holst D, Luquet S, Kristiansen K, Grimaldi PA EXP CELL RES 2003 288 1 168-176
    • (2003) Exp. Cell Res. , vol.288 , Issue.1 , pp. 168-176
    • Holst, D.1    Luquet, S.2    Kristiansen, K.3    Grimaldi, P.A.4
  • 49
    • 15844381118 scopus 로고    scopus 로고
    • Novartis shows dynamic momentum in industry-leading pipeline
    • 581315 PRESS RELEASE January 20
    • 581315 Novartis shows dynamic momentum in industry-leading pipeline. Novartis AG PRESS RELEASE 2005 January 20
    • (2005)
    • Novartis, A.G.1
  • 50
    • 2342573097 scopus 로고    scopus 로고
    • Glycemic treatment: Control of glycemia
    • 587224
    • 587224 Glycemic treatment: Control of glycemia. Bloomgarden ZT DIABETES CARE 2004 27 5 1227-1234
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1227-1234
    • Bloomgarden, Z.T.1
  • 51
    • 0347297125 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1: Does it play a role in diabetic nephropathy?
    • 587229
    • 587229 Monocyte chemoattractant protein-1: Does it play a role in diabetic nephropathy? Wada T, Yokoyama H, Matsushima K, Kobayashi K NEPHROL DIAL TRANSPLANT 2003 18 3 457-459
    • (2003) Nephrol. Dial. Transplant. , vol.18 , Issue.3 , pp. 457-459
    • Wada, T.1    Yokoyama, H.2    Matsushima, K.3    Kobayashi, K.4
  • 52
    • 0031425889 scopus 로고    scopus 로고
    • Decreased osteoblast activity in spontaneously diabetic rats. In vivo studies on the pathogenesis
    • 587231
    • 587231 Decreased osteoblast activity in spontaneously diabetic rats. In vivo studies on the pathogenesis. Verhaeghe J, Van Herck E, van Bree R, Moermans K, Bouillon R ENDOCRINE 1997 7 2 165-175
    • (1997) Endocrine , vol.7 , Issue.2 , pp. 165-175
    • Verhaeghe, J.1    Van Herck, E.2    van Bree, R.3    Moermans, K.4    Bouillon, R.5
  • 53
    • 0026521558 scopus 로고
    • 3 and corticosterone found in experimental diabetes reduces nerve growth factor (NGF) gene expression in vitro
    • 587233
    • 3 and corticosterone found in experimental diabetes reduces nerve growth factor (NGF) gene expression in vitro. Neveu I, Jehan F, Wion D LIFE SCI 1992 50 23 1769-1772
    • (1992) Life Sci. , vol.50 , Issue.23 , pp. 1769-1772
    • Neveu, I.1    Jehan, F.2    Wion, D.3
  • 54
    • 0141517123 scopus 로고    scopus 로고
    • Novel peroxisome proliferator-activated receptor ligands for type 2 diabetes and the metabolic syndrome
    • 587234
    • 587234 Novel peroxisome proliferator-activated receptor ligands for type 2 diabetes and the metabolic syndrome. Miller AR, Etgen GJ EXP OPIN INVESTIG DRUGS 2003 12 9 1489-1500
    • (2003) Exp. Opin. Investig. Drugs , vol.12 , Issue.9 , pp. 1489-1500
    • Miller, A.R.1    Etgen, G.J.2
  • 56
    • 0036847135 scopus 로고    scopus 로고
    • AZ 242, a novel PPARα/γ agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats
    • 587243
    • 587243 AZ 242, a novel PPARα/γ agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats. Ljung B, Bamberg K, Dahllof B, Kjellstedt A, Oakes ND, Ostling J, Svensson L, Camejo G J LIPID RES 2002 43 11 1855-1863
    • (2002) J. Lipid Res. , vol.43 , Issue.11 , pp. 1855-1863
    • Ljung, B.1    Bamberg, K.2    Dahllof, B.3    Kjellstedt, A.4    Oakes, N.D.5    Ostling, J.6    Svensson, L.7    Camejo, G.8
  • 57
    • 0031793850 scopus 로고    scopus 로고
    • A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-α (PPAR-α) and PPAR-γ. Effect of PPAR-α activation on abnormal lipid metabolism in liver of Zucker fatty rats
    • 587365
    • 587365 A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-α (PPAR-α) and PPAR-γ. Effect of PPAR-α activation on abnormal lipid metabolism in liver of Zucker fatty rats. Murakami K, Tobe K, Ide T, Mochizuki T, Ohashi M, Akanuma Y, Yazaki Y, Kadowaki T DIABETES 1998 47 12 1841-1847
    • (1998) Diabetes , vol.47 , Issue.12 , pp. 1841-1847
    • Murakami, K.1    Tobe, K.2    Ide, T.3    Mochizuki, T.4    Ohashi, M.5    Akanuma, Y.6    Yazaki, Y.7    Kadowaki, T.8
  • 60
    • 11144310564 scopus 로고    scopus 로고
    • An overview on biological mechanisms of PPARs
    • 587374
    • 587374 An overview on biological mechanisms of PPARs. Kota BP, Huang TH, Roufogalis BD PHARMACOL RES 2005 51 2 85-94
    • (2005) Pharmacol. Res. , vol.51 , Issue.2 , pp. 85-94
    • Kota, B.P.1    Huang, T.H.2    Roufogalis, B.D.3
  • 61
    • 11144349089 scopus 로고    scopus 로고
    • Up-regulation of PPARγ coactivator-1α as a strategy for preventing and reversing insulin resistance and obesity
    • 587375
    • 587375 Up-regulation of PPARγ coactivator-1α as a strategy for preventing and reversing insulin resistance and obesity. McCarty MF MED HYPOTHESES 2005 64 2 399-407
    • (2005) Med. Hypotheses , vol.64 , Issue.2 , pp. 399-407
    • McCarty, M.F.1
  • 62
    • 2942692043 scopus 로고    scopus 로고
    • Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression
    • 587658
    • 587658 Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression. Makimura H, Mizuno TM, Isoda F, Beasley J, Silverstein JH, Mobbs CV BMC PHYSIOL 3 1 5
    • BMC Physiol. , vol.3 , Issue.1 , pp. 5
    • Makimura, H.1    Mizuno, T.M.2    Isoda, F.3    Beasley, J.4    Silverstein, J.H.5    Mobbs, C.V.6
  • 64
    • 17644372246 scopus 로고    scopus 로고
    • 588299 Merck & Co. CREDIT SUISSE FIRST BOSTON February 22
    • 588299 Merck & Co. Arnold CJ, Gordon MI CREDIT SUISSE FIRST BOSTON 2005 February 22
    • (2005)
    • Arnold, C.J.1    Gordon, M.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.