Roles of peroxisome proliferator-activated receptors delta and gamma in myoblast transdifferentiation

Experimental Cell Research

Volumn 288, Issue 1, 2003, Pages 168-176

  Holst, Dorte ^a   Luquet, Serge ^b   Kristiansen, Karsten ^a   Grimaldi, Paul A ^b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b CENTRE DE BIOCHIMIE   (France)

Author keywords

Adipogenesis; Fatty acid; Myoblasts; MyoD1; PPAR

Indexed keywords

ALPHA ACTIN; BIOCHEMICAL MARKER; LONG CHAIN FATTY ACID; MYOD1 PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; THIAZOLIDINE DERIVATIVE;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; MOUSE; MUSCLE DEVELOPMENT; MYOBLAST; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATOR GENE;

RODENTIA;

EID: 0038148948     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00179-4     Document Type: Article

References (39)

1. Olson E.N., Klein W.H. bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out. Genes Dev. 8:1994;1-8.
2. Ailhaud G., Grimaldi P., Negrel R. Cellular and molecular aspects of adipose tissue development. Annu. Rev. Nutr. 12:1992;207-233.
3. Olson E.N. Interplay between proliferation and differentiation within the myogenic lineage. Dev. Biol. 154:1992;261-272.
4. Amri E.Z., Bonino F., Ailhaud G., Abumrad N.A., Grimaldi P.A. Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes: homology to peroxisome proliferator-activated receptors. J. Biol. Chem. 270:1995;2367-2371.
5. Bastie C., Holst D., Gaillard D., Jehl-Pietri C., Grimaldi P.A. Expression of peroxisome proliferator-activated receptor PPARdelta promotes induction of PPARgamma and adipocyte differentiation in 3T3C2 fibroblasts. J. Biol. Chem. 274:1999;21920-21925.
6. Forman B.M., Tontonoz P., Chen J., Brun R.P., Spiegelman B.M., Evans R.M. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 83:1995;803-812.
7. Lehmann J.M., Moore L.B., Smith-Oliver T.A., Wilkison W.O., Willson T.M., Kliewer S.A. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem. 270:1995;12953-12956.
8. Issemann I., Prince R.A., Tugwood J.D., Green S. The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J. Mol. Endocrinol. 11:1993;37-47.
9. Tontonoz P., Hu E., Graves R.A., Budavari A.I., Spiegelman B.M. PPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8:1994;1224-1234.
10. Altiok S., Xu M., Spiegelman B.M. PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev. 11:1997;1987-1998.
11. Mueller E., Sarraf P., Tontonoz P., Evans R.M., Martin K.J., Zhang M., Fletcher C., Singer S., Spiegelman B.M. Terminal differentiation of human breast cancer through PPAR gamma. Mol. Cell. 1:1998;465-470.
12. Mueller E., Smith M., Sarraf P., Kroll T., Aiyer A., Kaufman D.S., Oh W., Demetri G., Figg W.D., Zhou X.P., Eng C., Spiegelman B.M., Kantoff P.W. Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer. Proc. Natl. Acad. Sci. USA. 97:2000;10990-10995.
13. Sarraf P., Mueller E., Jones D., King F.J., DeAngelo D.J., Partridge J.B., Holden S.A., Chen L.B., Singer S., Fletcher C., Spiegelman B.M. Differentiation and reversal of malignant changes in colon cancer through PPARgamma. Nature Med. 4:1998;1046-1052.
14. Poirier H., Niot I., Monnot M.C., Braissant O., Meunier-Durmort C., Costet P., Pineau T., Wahli W., Willson T.M., Besnard P. Differential involvement of peroxisome-proliferator-activated receptors alpha and delta in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding protein in the liver and the small intestine. Biochem. J. 355:2001;481-488.
15. Bastie C., Luquet S., Holst D., Jehl-Pietri C., Grimaldi P.A. Alterations of peroxisome proliferator-activated receptor delta activity affect fatty acid-controlled adipose differentiation. J. Biol. Chem. 275:2000;38768-38773.
16. Jehl-Pietri C., Bastie C., Gillot I., Luquet S., Grimaldi P.A. Peroxisome-proliferator-activated receptor delta mediates the effects of long-chain fatty acids on post-confluent cell proliferation. Biochem. J. 350:(Pt. 1):2000;93-98.
17. Hansen J.B., Zhang H., Rasmussen T.H., Petersen R.K., Flindt E.N., Kristiansen K. Peroxisome proliferator-activated receptor delta (PPARdelta)-mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling. J. Biol. Chem. 276:2001;3175-3182.
18. He T.C., Chan T.A., Vogelstein B., Kinzler K.W. PPARdelta is an APC- regulated target of nonsteroidal anti-inflammatory drugs. Cell. 99:1999;335-345.
19. Park B.H., Vogelstein B., Kinzler K.W. Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc. Natl. Acad. Sci. USA. 98:2001;2598-2603.
20. Di-Poi N., Tan N.S., Michalik L., Wahli W., Desvergne B. Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol. Cell. 10:2002;721-733.
21. Hertz R., Berman I., Keppler D., Bar-Tana J. Activation of gene transcription by prostacyclin analogues is mediated by the peroxisome-proliferators-activated receptor (PPAR). Eur. J. Biochem. 235:1996;242-247.
22. Forman B.M., Chen J., Evans R.M. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc. Natl. Acad. Sci. USA. 94:1997;4312-4317.
23. Teboul L., Gaillard D., Staccini L., Inadera H., Amri E.Z., Grimaldi P.A. Thiazolidinediones and fatty acids convert myogenic cells into adipose- like cells. J. Biol. Chem. 270:1995;28183-28187.
24. Kausch C., Krutzfeldt J., Witke A., Rettig A., Bachmann O., Rett K., Matthaei S., Machicao F., Haring H.U., Stumvoll M. Effects of troglitazone on cellular differentiation, insulin signaling, and glucose metabolism in cultured human skeletal muscle cells. Biochem. Biophys. Res. Commun. 280:2001;664-674.
25. Nagy L., Tontonoz P., Alvarez J.G., Chen H., Evans R.M. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 93:1998;229-240.
26. Blau H.M., Pavlath G.K., Harderman E.C., Chiu C.P., Silberstein L., Webster S.G., Miller S.C., Webster C. Plasticity of the differentiated state. Science. 230:1985;758-766.
27. Pear W.S., Nolan G.P., Scott M.L., Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA. 90:1993;8392-8396.
28. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate- phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
29. Amri E.Z., Dani C., Doglio A., Etienne J., Grimaldi P., Ailhaud G. Adipose cell differentiation: evidence for a two-step process in the polyamine-dependent Ob1754 clonal line. Biochem. J. 238:1986;115-122.
30. Negrel R., Grimaldi P., Ailhaud G. Establishment of preadipocyte clonal line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones. Proc. Natl. Acad. Sci. USA. 75:1978;6054-6058.
31. Grimaldi P.A., Teboul L., Inadera H., Gaillard D., Amri E.Z. Trans- differentiation of myoblasts to adipoblasts: triggering effects of fatty acids and thiazolidinediones, Prostaglandins Leukotrienes Essent. Fatty Acids. 57:1997;71-75.
32. Ibrahimi A., Teboul L., Gaillard D., Amri E.Z., Ailhaud G., Young P., Cawthorne M.A., Grimaldi P.A. Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells. Mol. Pharmacol. 46:1994;1070-1076.
33. Zhang J.M., Wei Q., Zhao X., Paterson B.M. Coupling of the cell cycle and myogenesis through the cyclin D1- dependent interaction of MyoD with cdk4. EMBO J. 18:1999;926-933.
34. Auboeuf D., Rieusset J., Fajas L., Vallier P., Frering V., Riou J.P., Staels B., Auwerx J., Laville M., Vidal H. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes. 46:1997;1319-1327.
35. Hunter J.G., van Delft M.F., Rachubinski R.A., Capone J.P. Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma-dependent and-independent pathways. J. Biol. Chem. 276:2001;38297-38306.
36. Hu E., Tontonoz P., Spiegelman B.M. Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha. Proc. Natl. Acad. Sci. USA. 92:1995;9856-9860.
37. Storlien L.H., Jenkins A.B., Chisholm D.J., Pascoe W.S., Khouri S., Kraegen E.W. Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid. Diabetes. 40:1991;280-289.
38. Pan D.A., Lillioja S., Kriketos A.D., Milner M.R., Baur L.A., Bogardus C., Jenkins A.B., Storlien L.H. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes. 46:1997;983-988.
39. Perseghin G., Scifo P., De Cobelli F., Pagliato E., Battezzati A., Arcelloni C., Vanzulli A., Testolin G., Pozza G., Del Maschio A., Luzi L. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes. 48:1999;1600-1606.