-
2
-
-
0032933296
-
The biology of hormone refractory prostate cancer. Why does it develop?
-
Isaacs JT. The biology of hormone refractory prostate cancer. Why does it develop? Urol Clin North Am 1999;26:263-73.
-
(1999)
Urol Clin North Am
, vol.26
, pp. 263-273
-
-
Isaacs, J.T.1
-
3
-
-
0033520806
-
Prostate cancer cell cycle regulators: Response to androgen withdrawal and development of androgen independence
-
Agus DB, Cordon-Cardo C, Fox W, et al. Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence. J Natl Cancer Inst 1999;91:1869-76.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1869-1876
-
-
Agus, D.B.1
Cordon-Cardo, C.2
Fox, W.3
-
4
-
-
0036479998
-
Emerging targets in the AKT pathway for treatment of androgen-independent prostatic adenocarcinoma
-
Graff JR. Emerging targets in the AKT pathway for treatment of androgen-independent prostatic adenocarcinoma. Expert Opin Ther Targets 2002;6:103-13.
-
(2002)
Expert Opin Ther Targets
, vol.6
, pp. 103-113
-
-
Graff, J.R.1
-
6
-
-
0034749615
-
Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
-
Murillo H, Huang H, Schmidt LJ, Smith DI, Tindall DJ. Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology 2001;142:4795-805.
-
(2001)
Endocrinology
, vol.142
, pp. 4795-4805
-
-
Murillo, H.1
Huang, H.2
Schmidt, L.J.3
Smith, D.I.4
Tindall, D.J.5
-
7
-
-
0033957661
-
The PTEN tumor suppressor protein: An antagonist of phosphoinositide 3-kinase signaling
-
Vazquez F, Sellers WR. The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling. Biochim Biophys Acta 2000;1470:M21-35.
-
(2000)
Biochim Biophys Acta
, vol.1470
-
-
Vazquez, F.1
Sellers, W.R.2
-
8
-
-
0032126505
-
Frequent inactivation of PTEN in prostate cancer cell lines and xenografts
-
Vlietstra RJ, Van Alewijk DC, Hermans KG, Van Steenbrugge GJ, Trapman J. Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res 1998;58:2720-3.
-
(1998)
Cancer Res
, vol.58
, pp. 2720-2723
-
-
Vlietstra, R.J.1
Van Alewijk, D.C.2
Hermans, K.G.3
Van Steenbrugge, G.J.4
Trapman, J.5
-
9
-
-
0032431032
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
-
Wu X, Senegal K, Neshat MS, Whang YE, Sawyers CL. The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 1998;95:15587-91.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15587-15591
-
-
Wu, X.1
Senegal, K.2
Neshat, M.S.3
Whang, Y.E.4
Sawyers, C.L.5
-
10
-
-
0032574718
-
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression
-
Whang YE, Wu X, Suzuki H, et al. Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. Proc Natl Acad Sci U S A 1998;95:5246-50.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5246-5250
-
-
Whang, Y.E.1
Wu, X.2
Suzuki, H.3
-
11
-
-
0033200172
-
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
-
McMenamin ME, Soung P, Perera S, Kaplan I, Loda M, Sellers WR. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res 1999;59:4291-6.
-
(1999)
Cancer Res
, vol.59
, pp. 4291-4296
-
-
McMenamin, M.E.1
Soung, P.2
Perera, S.3
Kaplan, I.4
Loda, M.5
Sellers, W.R.6
-
12
-
-
0036554734
-
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer
-
Malik SN, Brattain M, Ghosh PM, et al. Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin Cancer Res 2002;8:1168-71.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1168-1171
-
-
Malik, S.N.1
Brattain, M.2
Ghosh, P.M.3
-
13
-
-
0034609737
-
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
-
Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 2000;10:1201-4.
-
(2000)
Curr Biol
, vol.10
, pp. 1201-1204
-
-
Dijkers, P.F.1
Medema, R.H.2
Lammers, J.W.3
Koenderman, L.4
Coffer, P.J.5
-
14
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999;96:857-68.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
-
15
-
-
0034643331
-
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema RH, Kops GJ, Bos JL, Burgering BM. AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 2000;404:782-7.
-
(2000)
Nature
, vol.404
, pp. 782-787
-
-
Medema, R.H.1
Kops, G.J.2
Bos, J.L.3
Burgering, B.M.4
-
16
-
-
0034459180
-
Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1)
-
Dijkers PF, Medema RH, Pals C, et al. Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1). Mol Cell Biol 2000;20:9138-48.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9138-9148
-
-
Dijkers, P.F.1
Medema, R.H.2
Pals, C.3
-
17
-
-
0034462121
-
Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN
-
Nakamura N, Ramaswamy S, Vazquez F, Signoretti S, Loda M, Sellers WR. Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. Mol Cell Biol 2000;20:8969-82.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8969-8982
-
-
Nakamura, N.1
Ramaswamy, S.2
Vazquez, F.3
Signoretti, S.4
Loda, M.5
Sellers, W.R.6
-
18
-
-
0035909313
-
Forkhead transcription factors contribute to execution of the mitotic programme in mammals
-
Alvarez B, Martinez AC, Burgering BMT, Carrera AC. Forkhead transcription factors contribute to execution of the mitotic programme in mammals. Nature 2001;413:744-7.
-
(2001)
Nature
, vol.413
, pp. 744-747
-
-
Alvarez, B.1
Martinez, A.C.2
Burgering, B.M.T.3
Carrera, A.C.4
-
19
-
-
0036120725
-
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors
-
Kops GJ, Medema RH, Glassford J, et al. Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Mol Cell Biol 2002;22:2025-36.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2025-2036
-
-
Kops, G.J.1
Medema, R.H.2
Glassford, J.3
-
20
-
-
0037094096
-
The Forkhead transcription factor FOXO regulates transcription of p27KIP1 and Bim in response to IL-2
-
Stahl M, Dijkers PF, Kops GJ, et al. The Forkhead transcription factor FOXO regulates transcription of p27KIP1 and Bim in response to IL-2. J Immunol 2002;168:5024-31.
-
(2002)
J Immunol
, vol.168
, pp. 5024-5031
-
-
Stahl, M.1
Dijkers, P.F.2
Kops, G.J.3
-
21
-
-
0037458609
-
A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells
-
Komatsu N, Watanabe T, Uchida M, et al. A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells. J Biol Chem 2003;278:6411-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 6411-6419
-
-
Komatsu, N.1
Watanabe, T.2
Uchida, M.3
-
22
-
-
0035034038
-
Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX
-
Brownawell AM, Kops GJ, Macara IG, Burgering BM. Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. Mol Cell Biol 2001;21:3534-46.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3534-3546
-
-
Brownawell, A.M.1
Kops, G.J.2
Macara, I.G.3
Burgering, B.M.4
-
23
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs WH, Meisenhelder J, Hunter T, Cavenee WK, Arden KC. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci U S A 1999;96:7421-6.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7421-7426
-
-
Biggs, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
24
-
-
0039425278
-
Negative regulation of the forkhead transcription factor FKHR by Akt
-
Tang ED, Nunez G, Barr FG, Guan KL. Negative regulation of the forkhead transcription factor FKHR by Akt. J Biol Chem 1999;274:16741-6.
-
(1999)
J Biol Chem
, vol.274
, pp. 16741-16746
-
-
Tang, E.D.1
Nunez, G.2
Barr, F.G.3
Guan, K.L.4
-
25
-
-
13044315956
-
Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B
-
Takaishi H, Konishi H, Matsuzaki H, et al. Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B. Proc Natl Acad Sci U S A 1999;96:11836-41.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11836-11841
-
-
Takaishi, H.1
Konishi, H.2
Matsuzaki, H.3
-
26
-
-
0037323903
-
Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors
-
Birkenkamp KU, Coffer PJ. Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors. Biochem Soc Trans 2003;31:292-7.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 292-297
-
-
Birkenkamp, K.U.1
Coffer, P.J.2
-
27
-
-
0038362751
-
Akt activation promotes degradation of tuberin and FOXO3a via the proteasome
-
Plas DR, Thompson CB. Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. J Biol Chem 2003;278:12361-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 12361-12366
-
-
Plas, D.R.1
Thompson, C.B.2
-
28
-
-
0037033005
-
FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer
-
Modur V, Nagarajan R, Evers BM, Milbrandt J. FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. J Biol Chem 2002;277:47928-37.
-
(2002)
J Biol Chem
, vol.277
, pp. 47928-47937
-
-
Modur, V.1
Nagarajan, R.2
Evers, B.M.3
Milbrandt, J.4
-
29
-
-
0033527656
-
Sp1 and NF-Y synergistically mediate the effect of vitamin D(3) in the p27(Kip1) gene promoter that lacks vitamin D response elements
-
Inoue T, Kamiyama J, Sakai T. Sp1 and NF-Y synergistically mediate the effect of vitamin D(3) in the p27(Kip1) gene promoter that lacks vitamin D response elements. J Biol Chem 1999;274:32309-17.
-
(1999)
J Biol Chem
, vol.274
, pp. 32309-32317
-
-
Inoue, T.1
Kamiyama, J.2
Sakai, T.3
-
30
-
-
2542437988
-
The major transcription initiation site of the p27Kip1 gene is conserved in human and mouse and produces a long 5′-UTR
-
Coleman J, Hawkinson M, Miskimins R, Miskimins WK. The major transcription initiation site of the p27Kip1 gene is conserved in human and mouse and produces a long 5′-UTR. BMC Mol Biol 2001;2:12.
-
(2001)
BMC Mol Biol
, vol.2
, pp. 12
-
-
Coleman, J.1
Hawkinson, M.2
Miskimins, R.3
Miskimins, W.K.4
-
31
-
-
0033546192
-
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
-
Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T. Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J Biol Chem 1999;274:17184-92.
-
(1999)
J Biol Chem
, vol.274
, pp. 17184-17192
-
-
Guo, S.1
Rena, G.2
Cichy, S.3
He, X.4
Cohen, P.5
Unterman, T.6
-
32
-
-
0038363836
-
Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16
-
Imae M, Fu Z, Yoshida A, Noguchi T, Kato H. Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16. J Mol Endocrinol 2003;30:253-62.
-
(2003)
J Mol Endocrinol
, vol.30
, pp. 253-262
-
-
Imae, M.1
Fu, Z.2
Yoshida, A.3
Noguchi, T.4
Kato, H.5
-
33
-
-
0036191716
-
Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: Evidence for regulation by IGF-I, estrogen, and the gonadotropins
-
Richards JS, Sharma SC, Falender AE, Lo YH. Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins. Mol Endocrinol 2002;16:580-99.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 580-599
-
-
Richards, J.S.1
Sharma, S.C.2
Falender, A.E.3
Lo, Y.H.4
-
34
-
-
1842690558
-
Androgens negatively regulate forkhead transcription factor FKHR (FOXO1) through a proteolytic mechanism in prostate cancer cells
-
Huang H, Muddiman DC, Tindall DJ. Androgens negatively regulate forkhead transcription factor FKHR (FOXO1) through a proteolytic mechanism in prostate cancer cells. J Biol Chem 2004;279:13866-77.
-
(2004)
J Biol Chem
, vol.279
, pp. 13866-13877
-
-
Huang, H.1
Muddiman, D.C.2
Tindall, D.J.3
-
35
-
-
0031683673
-
Prostate stem cell compartments: Expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells
-
De Marzo AM, Meeker AK, Epstein JI, Coffey DS. Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. Am J Pathol 1998;153:911-9.
-
(1998)
Am J Pathol
, vol.153
, pp. 911-919
-
-
De Marzo, A.M.1
Meeker, A.K.2
Epstein, J.I.3
Coffey, D.S.4
-
36
-
-
0031409280
-
Loss of the cyclin-dependent kinase inhibitor p27(Kip1) protein in human prostate cancer correlates with tumor grade
-
Guo Y, Sklar GN, Borkowski A, Kyprianou N. Loss of the cyclin-dependent kinase inhibitor p27(Kip1) protein in human prostate cancer correlates with tumor grade. Clin Cancer Res 1997;3:2269-74.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2269-2274
-
-
Guo, Y.1
Sklar, G.N.2
Borkowski, A.3
Kyprianou, N.4
-
37
-
-
0037216526
-
AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR
-
Li P, Lee H, Guo S, Unterman TG, Jenster G, Bai W. AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR. Mol Cell Biol 2003;23:104-18.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 104-118
-
-
Li, P.1
Lee, H.2
Guo, S.3
Unterman, T.G.4
Jenster, G.5
Bai, W.6
-
38
-
-
0028884426
-
Transcriptional modulators affect in vivo protein binding to the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase promoters
-
Lloyd DB, Thompson JF. Transcriptional modulators affect in vivo protein binding to the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase promoters. J Biol Chem 1995;270:25812-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 25812-25818
-
-
Lloyd, D.B.1
Thompson, J.F.2
|