Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

British Journal of Clinical Pharmacology

Volumn 59, Issue 4, 2005, Pages 415-424

  Zhou, Qingyu ^a   Sparreboom, Alex ^b   Tan, Eng Huat ^a   Cheung, Yin Bun ^a   Lee, Ann ^a   Poon, Donald ^a   Lee, Edmund J D ^c   Chowbay, Balram ^a  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

ABC transporters; Drug metabolizing enzymes; Single nucleotide polymorphisms

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 ETHYL 10 HYDROXYCAMPTOTHECIN GLUCURONIDE; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE 1A1; IRINOTECAN;

ABCB1 GENE; ABCG2 GENE; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; ASIAN; CANCER PATIENT; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG HALF LIFE; ETHNIC GROUP; EXON; FEMALE; GENE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MALE; NASOPHARYNX CARCINOMA; NUCLEOTIDE SEQUENCE; PHARMACOGENETICS; PRIORITY JOURNAL;

ADULT; AGED; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; ASIAN CONTINENTAL ANCESTRY GROUP; ATP-BINDING CASSETTE TRANSPORTERS; CAMPTOTHECIN; FEMALE; GENES, MDR; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; NEOPLASM PROTEINS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 17144413348     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2004.02330.x     Document Type: Article

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