Identification of a new metabolite of CPT-11 (irinotecan): Pharmacological properties and activation to SN-38

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 1, 1998, Pages 578-583

  Dodds, Helen M ^b   Haaz, Marie Christine ^a   Riou, Jean François ^c   Robert, Jacques ^a   Rivory, Laurent P ^b,d  

^a INSTITUT BERGONIÉ   (France)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c SANOFI   (France)

^d ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 (4 AMINO 1 PIPERIDINO)CARBONYLOXYCAMPTOTHECIN; IRINOTECAN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL GROWTH; DNA CLEAVAGE; DRUG IDENTIFICATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIVER MICROSOME; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOTRANSFORMATION; CAMPTOTHECIN; HUMANS; LEUKEMIA P388; MICROSOMES, LIVER; TUMOR CELLS, CULTURED;

EID: 0031871505     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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