Pharmacology and biology of corticotropin-releasing factor (CRF) receptors

Receptors and Channels

Volumn 8, Issue 3-4, 2002, Pages 163-177

  Eckart, K ^a   Jahn, O ^a   Radulovic, J ^a   Radulovic, M ^a   Blank, T ^a   Stiedl, O ^a   Brauns, O ^a   Tezval, H ^a   Zeyda, T ^a   Spiess, J ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Anxiety; Cardiovascular modulation; Corticotropin releasing factor binding protein; Immune cells; Stress; Urocortin

Indexed keywords

APOPTOSIS INHIBITOR; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR DERIVATIVE; CORTICOTROPIN RELEASING FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; LIGAND; CARRIER PROTEIN; CORTICOTROPIN RELEASING FACTOR BINDING PROTEIN; CORTICOTROPIN RELEASING FACTOR-BINDING PROTEIN; CRF RECEPTOR TYPE 1; CRF(2ALPHA) RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANXIETY; APOPTOSIS; BIOLOGY; BRAIN FUNCTION; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; EXON; FEEDING; FEMALE; GENE STRUCTURE; GENETIC TRANSDUCTION; HORMONE ACTION; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; INTRON; LEARNING; LOCOMOTION; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR GENE; REVIEW; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANIMAL; BEHAVIOR; BINDING SITE; DRUG ANTAGONISM; GENETICS; METABOLISM; MOLECULAR GENETICS; NERVE CELL; PHYSIOLOGY; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BEHAVIOR; BINDING SITES; CARRIER PROTEINS; CORTICOTROPIN-RELEASING HORMONE; GTP-BINDING PROTEINS; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; NEURONS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 17044461212     PISSN: 10606823     EISSN: None     Source Type: Journal    
DOI: 10.1080/10606820213678     Document Type: Review

References (184)

1. Aldenhoff, J. B., Gruol, D. L., Rivier, J., Vale, W. W., and Siggins, G. R. 1983. Science 221:875-877.
2. Alger, B. E., and Nicoll, R. A. 1980. Science 210:1122-1124.
3. Arai, M., Assil, I.Q., and Abou-Samra, A. B. 2001. Endocrinology 142:446-454.
4. Arunlakshana, O., and Schild, H. O. 1959. Br. J. Pharmacol. 14:48-58.
5. Assil, I. Q., and Abou-Samra, A. B. 2001. Am. J. Physiol. Endocrinol. Metab. 281:E1015-E1021.
6. Assil, I. Q., Qi, L. J., Arai, M., Shomali, M., and Abou-Samra, A. B. 2001. Biochemistry 40:1187-1195.
7. Bakshi, V. P., and Kalin, N. H. 2000. Biol. Psychiatry 48:1175-1198.
8. Baldwin, H. A., Rassnick, S., Rivier, J., Koob, G. F., and Britton, K. T. 1991. Psychopharmacology 103:227-232.
9. Bale, T. L., Contarino, A., Smith, G. W., Chan, R., Gold, L. H., Sawchenko, P. E., Koob, G. F., Vale, W. W., and Lee, K.-F. 2000. Nat. Genet. 24:410-414.
10. Baram, T Z., and Hatalski, C. G. 1998. Trends Neurosci. 21:471-476.
11. Baram, T Z., Koutsoukos, Y., Schultz, L., and Rivier, J. 1996. Mol. Psychiatry 1:223-226.
12. Behan, D. P., Grigoriadis, D. E., Lovenberg, T., Chalmers, D., Heinrichs, S. Liaw, C., and De Souza, E. B. 1996a. Mol. Psychiatry 1:265-277.
13. Behan, D. P., Heinrichs, S. C., Troncoso, J. C., Liu, X. J., Kawas, C. H., Ling, N., and De Souza, E. B. 1995. Nature 378:284-287.
14. Behan, D. P., Khongsaly, O., Ling, N., and De Souza, E. B. 1996. Brain Res. 725:263-267.
15. Berridge, C. W., and Dunn, A. J. 1987. Horm. Behav. 21:393-401.
16. Bethin, K. E., Vogt, S. K., and Muglia, L. J. 2000. Proc. Natl. Acad. Sci. USA 97:9317-9322.
17. Beyermann, M., Fechner, K., Furkert, J., Krause, E., and Bienert, M. 1996. J. Med. Chem. 39:3324-3330.
18. Bradbury, M. J., McBurnie, M. I., Denton, D. A., Lee, K. F., and Vale, W. W. 2000. Endocrinology 141:2715-2724.
19. Brar, B. K., Jonassen, A. K., Stephanou, A., Santilli, G., Railson, J., Knight, R., Yellon, D. M., and Latchman, D. S. 2000. J. Biol. Chem. 275:8508-8514.
20. Brar, H. K., Stephanou, A., Okosi, A., Lawrence, K. M., Knight, R. A., Marber,M.S., and Latchman, D. S. 1999. Mol. Cell Endocrinol. 158:55-63.
21. Brauns, O., Liepold, T., Radulovic, J., and Spiess, J. 2001. Neuropharmacology 41:507-516.
22. Britton, K. T., Lee, G., Vale, W. W., Rivier, J., and Koob, G. F. 1986. Brain Res. 369:303-306.
23. Brown, M. R., Fisher, L. A., Spiess, J., Rivier, C., Rivier, J., and Vale, W. W. 1982. Endocrinology 111:928-931.
24. Brown, M. R., Gray, T S., and Fisher, L. A. 1986. Regul. Pept. 16:321-329.
25. Buwalda, B., Van Kalkeren, A. A.,Boer, S. F., and Koolhaas, J. M. 1998. Psychoneuroendocrinology 23:205-218.
26. Casadevall, M., Saperas, E., Panes, J., Salas, A., Anderson, D. C., Malagelada, J. R., and Pique, J. M. 1999. Am. J. Physiol. Gastroint. Liver Physiol. 276:G1016-G1O26.
27. Cervini, L., Theobald, P., Corrigan, A., Craig, A. G., Rivier, C., Vale, W., and Rivier, J. 1999. J. Med. Chem. 42:761-768.
28. Chalmers, D. T., Lovenberg, T. W., and De Souza, E. B. 1995. J. Neurosci. 15:6340-6350.
29. Chang, C. P., Pearse, R. V., O'Connell, S., and Rosenfeld, M. G. 1993. Neuron 11:1187-1195.
30. Chatterjee, T. K., Liu, X. B., Davisson, R. L., and Fisher, R. A. 1997. J. Biol. Chem. 272:12122-12131.
31. Chen, R., Lewis, K. A., Perrin, M. H., and Vale, W. W. 1993. Proc. Natl. Acad. Sci. USA 90:8967-8971.
32. Contarino, A., Dellu, F., Koob, G., Smith, G., Lee, K., Vale, W., and Gold, L. 2000. Endocrinology 141:2698-2702.
33. Conti, L. H., Costello, D. G., Martin, L. A., White, M. F., and Abreu, M. E. 1994. Pharmacol. Biochem. & Behav. 48:497-503.
34. Correa, S., Riera, C. M., Spiess, J., and Bianco, I.D. 1997. Eur. J. Pharmacol. 319:85-90.
35. Coste, S. C., Kesterson, R. A., Heldwein, K. A., Stevens, S. L., Heard, A.D., Hollis, J. H., Murray, S. E., Pantely, G. A., Hohimer, A. R., Hatton, D. C., Phillips, T. J., Finn, D. A., Low, M. J., Rittenberg, M. B., Stenzel, P., and Stenzel-Poore, M. P. 2000. Nat. Genet. 24:403-409.
36. Cullen, M. J., Ling, N., Foster, A. C., and Pelleymounter, M. A. 2001. Endocrinology 142:992-999.
37. Cummings, S., Elde, R., Ells, J., and Lindall, A. 1983. J. Neurosci. 3:1355-1368.
38. Cummings, S., Sharp, B., and Elde, R. 1988. J. Neurosci. 8:543-554.
39. Dathe, M., Fabian, H., Gast, K., Zirwer, D., Winter, R., Beyermann, M., Schumann, M., and Bienert, M. 1996. Int. J. Peptide Protein Res. 47:383-393.
40. Dautzenberg, F. M., Dietrich, K., Palchaudhuri, M. R., and Spiess, J. 1997. J. Neurochem. 69:1640-1649.
41. Dautzenberg, F. M., Kilpatrick, G. J., Hauger, R. L., and Moreau, J. L. 2001. Peptides 22:753-760.
42. Dautzenberg, F. M., Wille, S., Lohmann, R., and Spiess, J. 1998. Proc. Natl. Acad. Sci. USA 95:4941-4946.
43. Diamant, M., and de Wied, D. 1993. Neuroendocrinol. 57:1071-1081.
44. Dinarello, C. A. 1994. FASEB J. 8:1314-1325.
45. Dunn, A. J., and Berridge, C. W. 1990. Brain Res. Rev. 15:71-100.
46. Dunn, A. J., and File, S. E. 1987. Horm. Behav. 21:193-202.
47. Eckart, K., Jahn, O., Radulovic, J., Tezval, H., van Werven, L., and Spiess, J. 2001. Proc. Natl. Acad. Sci. USA 98:11142-11147.
48. Eckart, K., Radulovic, J., Radulovic, M., Jahn, O., Blank, T., Stiedl, O., and Spiess, J. 1999. Curr. Med. Chem. 6:1035-1053.
49. Elbein, A. D., Tropea, J. E., Mitchell, M., and Kaushal, G. P. 1990. J. Biol. Chem. 265:15599-15605.
50. Fisher, L., Rivier, C., Rivier, J., and Brown, M. 1991. Endocrinology 129:1312-1316.
51. Fisher, L. A. 1989. Trends Pharmacol. Sci. 10:189-193.
52. Foris, G., Medgyesi, G. A., Nagy, J. T., and Varga, Z. 1987. Annals of the New York Academy of Sciences 496:151-157.
53. Fox, E. A., and Gruol, D. L. 1993. Neurosci. Lett. 149:103-107.
54. Genedani, S., Bernardi, M., Baldini, M. G., and Bertolini, A. 1992. Neuropeptides 23:99-102.
55. Grammatopoulos, D. K., Dai, Y. L., Randeva, H. S., Levine, M. A., Karteris, E., Easton, A. J., and Hillhouse, E. W. 1999. Mol. Endocrinol. 13:2189-2202.
56. Grammatopoulos, D. K., Randeva, H. S., Levine, M. A., Katsanou, E. S., and Hilhouse, E. W. 2000. Mol. Endocrinol. 14:2076-2091.
57. Gulyas, J., Rivier, C., Perrin, M., Koerber, S. C., Sutton, S., Corrigan, A., Lahrichi, S. L., Craig, A. G., Vale, W., and Rivier, J. 1995. Proc. Natl. Acad. Sci. USA 92:10575-10579.
58. Harada, H., Becknell, B., Wilm, M., Mann, M., Huang, L. J. S., Taylor, S. S., Scott, J. D., and Korsmeyer, S. J. 1999. Mol. Cell 3:413-422.
59. Heinrichs, S. C., Vale, E. A., Lapsansky, J., Behan, D. P., McClure, L. V., Ling, N., De Souza, E. B., and Schulteis, G. 1997. Peptides 18:711-716.
60. Henaff, M., Hatem, S. N., and Mercadier, J. J. 2000. Mol. Pharmacol. 58:1546-1553.
61. Hendricks, G. L., Mashaly, M. M., and Siegel, H. S. 1995. Esp. Biol. & Med. 209:382-386.
62. Hernandez, J. F., Kornreich, W., Rivier, C., Miranda, A., Yamamoto, G., Andrews, J., Tache, Y., Vale, W., and Rivier, J. 1993. J. Med. Chem. 36:2860-2867.
63. Ho, S. P., Takahashi, L. K., Livanov, V., Spencer, K., Lesher, T., Maciag, C., Smith, M. A., Rohrbach, K. W., Hartig, P. R., and Arneric, S. P. 2001. Mol. Brain Res. 89:29-40.
64. Hofmann, B. A., Sydow, S., Jahn, O., van Werven, L., Liepold, T., Eckart, K., and Spiess, J. 2001. Protein Sci. 10:2050-2062.
65. Hotson, J. R., and Prince, D. A. 1980. J. Neurophysiol. 43:409-419.
66. Hsu, S. Y., and Hsueh, A. J. W. 2001. Nat. Med. 7:605-611.
67. Iavicoli, S., Lopez-Perez, E., Buehring, G. C., Thomas, H. A., Wei, E. T., and Kishimoto, T. 1998. Eur. J. Pharmacol. 349:301-306.
68. Irwin, M., Hauger, R. L., Brown, M., and Britton, K. T. 1988. Am. J. Physiol. 255:R744-R747.
69. Jahn, O., Eckart, K., Sydow, S., Hofmann, B. A., and Spiess, J. 2001. Peptides 22:47-56.
70. Karalis, K., Sano, H., Redwine, J., Listwak, S., Wilder, R. L., and Chrousos, G. P. 1991. Science 254:421-423.
71. Karolyi, I. J., Burrows, H. L., Ramesh, T. M., Nakajima, M., Lesh, J. S., Seong, E., Camper, S. A., and Seasholtz, A. F. 1999. Proc. Natl. Acad. Sci. USA 96:11595-11600.
72. Karteris, E., Grammatopoulos, D. K., Randeva, H. S., and Hillhouse, E. W. 2001. Mol. Genet. Metab. 72:287-296.
73. Keller, P. A., Elfick, L., Garner, J., Morgan, J., and McCluskey, A. 2000. Bioorg. Med. Chem. 8:1213-1223.
74. Kemp, C. F., Woods, R. J., and Lowry, P. J. 1998. Peptides 19:1119-1128.
75. Kishimoto, T., Pearse, R. V., Lin, C. R., and Rosenfeld, M. G. 1995. Proc. Natl. Acad. Sci. USA 92:1108-1112.
76. Kishimoto, T., Radulovic, J., Radulovic, M., Lin, C. R., Schrick, C., Hooshmand, F., Hermanson, O., Rosenfeld, M. G., and Spiess, J. 2000. Nat. Genet. 24:415-419.
77. Koerber, S. C., Gulyas, J., Lahrichi, S. L., Corrigan, A., Craig, A. G., Rivier, C., Vale, W., and Rivier, J. 1998. J. Med. Chem. 41:5002-5011.
78. Koob, G. F., and Bloom, F. E. 1985. Federation Proceedings 44:259-263.
79. Koob, G. F., and Heinrichs, S. C. 1999. Brain Res. 848:141-152.
80. Kornreich, W. D., Galyean, R., Hernandez, J. F., Craig, A. G., Donaldson, C. J., Yamamoto, G., Rivier, C., Vale, W. W., and Rivier, J. 1992. J. Med. Chem. 35:1870-1876.
81. Koshida, H., and Kotake, Y. 1994. Lile Sci. 54:539-543.
82. Kostich, W. A., Chen, A., Sperle, K., and Largent, B. L. 1998. Mol. Endocrinol. 12:1077-1085.
83. Kozicz, T., Yanaihara, H., and Arimura, A. 1998. J. Comp. Neurol. 391:1-10.
84. Krahn, D. D., Gosnell, B. A., Grace, M., and Levine, A. S. 1986. Brain Res. Bull. 17:285-289.
85. Lau, S. H., Rivier, J., Vale, W., Kaiser, E. T., and Kézdy, F. J. 1983. Proc. Natl. Acad. Sci. USA 80:7070-7074.
86. Lederis, K., Letter, A., McMaster, D., and Moore, G. 1982. Science 218:162-164.
87. Lei, S., Richter, R., Bienert, M., and Mulvany, M. J. 1993. Br. J. Pharmacol. 108:941-947.
88. Leu, S. J., and Singh, V. K. 1992. Cell Immunol. 143:220-227.
89. Lewis, K., Li, C., Perrin, M. H., Blount, A., Kunitake, K., Donaldson, C., Vaughan, J., Reyes, T. M., Gulyas, J., Fischer, W., Bilezikjian, L., Rivier, J., Sawchenko, P. E., and Vale, W. W. 2001. Proc. Natl. Acad. Sci. USA 98:7570-7575.
90. Lezoualc'h, F., Engert, S., Berning, B., and Behl, C. 2000. Mol. Endocrinol. 14:147-159.
91. Liang, K. C., and Lee, E. H. 1988. Psychopharmacology 96:232-236.
92. Liaw, C. W., Grigoriadis, D. E., Lorang, M. T., Desouza, E. B., and Maki, R. A. 1997. Mol. Endocrinol. 11:2048-2053.
93. Liaw, C. W., Lovenberg, T. W., Barry, G., Oltersdorf, T., Grigoriadis, D. E., and de Souza, E. B. 1996. Endocrinology 137:72-77.
94. Liu, M., Parker, R. M. C., Darby, K., Eyre, H. J., Copeland, N. G., Crawford, J., Gilbert, D. J., Sutherland, G. R., Jenkins, N. A., and Herzog, H. 1999. Genomics 55:296-305.
95. Lovejoy, D. A., and Balment, R. J. 1999. Gen. Comp. Endocrinol. 115:1-22.
96. Lovenberg, T., Liaw, C., Grigoriadis, D., Clevenger, W., Chalmers, D., De Souza, E., and Oltersdorf, T. 1995a. Proc. Natl. Acad. Sci. USA 92:836-840.
97. Lovenberg, T. W., Chalmers, D. T., Liu, C., and De Souza, E. B. 1995a. Endocrinology 136:4139-4142.
98. Lowry, C. A., Rodda, J. E., Lightman, S. L., and Ingram, C. D. 2000. J. Neurosci. 20:7728-7736.
99. Lu, L., Liu, D. H., Ceng, X. B., and Ma, L. 2000. Eur. J. Neurosci. 12:4398-4404.
100. MacKay, D. 1978. J. Pharm. Pharmacol. 30:312-313.
101. McGillis, J. P., Park, A., Rubin-Fletter, P., Turck, C., Dallman, M. F., and Payan, D. G. 1989. J. Neurosci. Res. 23:346-352.
102. Menzaghi, F, Howard, R., Heinrichs, S., Vale, W., Rivier, J., and Koob, G. 1994. J. Pharmacol. Exp. Ther. 269:564-572.
103. Miranda, A., Koerber, S. C., Gulyas, J., Lahrichi, S. L., Craig, A. G., Corrigan, A., Hagler, A., Rivier, C., Vale, W., and Rivier, J. 1994. J. Med. Chem. 37:1450-1459.
104. Miyata, I., Shiota, C., Ikeda, Y., Oshida, Y., Chaki, S., Okuyama, S., and Inagami, T. 1999a. Biochem. Biophys. Res. Commun. 256:692-696.
105. Miyata, M., Okada, D., Hashimoto, K., Kano, M., and Ito, M. 1999b. Neuron 22:763-775.
106. Moga, M. M., and Gray, T. S. 1985. J. Comp. Neurol. 241:275-284.
107. Montecucchi, P., and Henschen, A. 1981. Int. J. Peptide Protein Res. 18:113-120.
108. Muglia, L., Jacobson, L., Dikkes, R, and Majzoub, J. A. 1995. Nature 373:427-432.
109. Myers, D. A., Trinh, J. V., and Myers, T. R. 1998. Mol. Cell Endocrinol. 144:21-35.
110. Nielsen, S. M., Nielsen, L. Z., Hjorth, S. A., Perrin, M. H., and Vale, W. W. 2000. Proc. Natl. Acad. Sci. USA 97:10277-10281.
111. Olschowka, J. A., O'Donohue, T. L., Mueller, G. P., and Jacobowitz, D. M. 1982. Peptides 3:995-1015.
112. Owens, M. J., and Nemeroff, C. B. 1991. Pharmacol. Rev. 43:425-473.
113. Palchaudhuri, M. R., Wille, S., Mevenkamp, G., Spiess, J., Fuchs, E., and Dautzenberg, F. M. 1998. Eur. J. Biochem. 258:78-84.
114. Pallai, P. V., Mabilia, M., Goodman, M., Vale, W., and Rivier, J. 1983. Proc. Natl. Acad. Sci. USA 80:6770-6774.
115. Parkes, D. G., Weisinger, R. S., and May, C. N. 2001. Peptides 22:821-827.
116. Parvathenani, L. K., Calandra, V., Roberts, S. B., and Posmantur, R. 2000. Neuroreport 11:2293-2297.
117. Pedersen, W. A., McCullers, D., Culmsee, C., Haughey, N. J., Herman, J. P., and Mattson, M. P. 2001. Neurobiol. Dis. 8:492-503.
118. Pelleymounter, M. A., Joppa, M., Carmouche, M., Cullen, M. J., Brown, B., Murphy, B., Grigoriadis, D. E., Ling, N., and Foster, A. C. 2000. J. Pharmacol. Exp. Ther. 293:799-806.
119. Perrin, M., Donaldson, C., Chen, R., Blount, A., Berggren, T., Bilezikjian, L., Sawchenko, P, and Vale, W. 1995. Proc. Natl. Acad. Sci. USA 92:2969-2973.
120. Perrin, M. H., Donaldson, C. J., Chen, R., Lewis, K. A., and Vale, W. W. 1993. Endocrinology 133:3058-3061.
121. Perrin, M. H., Fischer, W. H., Kunitake, K. S., Craig, A. G., Koerber, S. C., Cervini, L. A., Rivier, J. E., Groppe, J. C., Greenwald, J., Nielsen, S. M., and Vale, W. W. 2001. J. Biol. Chem. 276:31528-31534.
122. Perrin, M. H., Sutton, S., Bain, D. L., Berggren, W. T., and Vale, W. W. 1998. Endocrinology 139:566-570.
123. Perrin, M. H., Sutton, S. W., Cervini, L. A., Rivier, J. E., and Vale, W.W. 1999. J. Pharmacol. Exp. Ther. 288:729-734.
124. Perrin, M. H., and Vale, W. W. 1999. Annals of the New York Academy of Sciences 885:312-328.
125. Poliak, S., Mor, F., Conlon, P., Wong, T., Ling, N., Rivier, J., Vale, W. W., and Steinman, L. 1997. J. Immunol. 158:5751-5756.
126. Potter, E., Behan, D. P., Fischer, W. H., Linton, E. A., Lowry, P. J., and Vale, W. W. 1991. Nature 349:423-426.
127. Potter, E., Behan, D. P., Linton, E. A., Lowry, P. J., Sawchenko, P. E., and Vale, W. W. 1992. Proc. Natl. Acad. Sci. USA 89:4192-4196.
128. Potter, E., Sutton, S., Donaldson, C., Chen, R., Perrin, M., Lewis, K., Sawchenko, P. E., and Vale, W. W. 1994. Proc. Natl. Acad. Sci. USA 91:8777-8781.
129. Qi, L. J., Leung, A. T., Xiong, Y. T., Marx, K. A., and Abou-Samra, A. B. 1997. Biochemistry 36:12442-12448.
130. Radulovic, J., Blank, T., Eckart, K., Radulovic, M., Stiedl, O., and Spiess, J. 1999a. CRF and CRF receptors. In Regulatory Peptides and Cognate Receptors, ed. D. Richter, 67-90. Heidelberg, Germany: Springer.
131. Radulovic, J., Rühmann, A., Liepold, T., and Spiess, J. 1999b. J. Neurosci. 19:5016-5025.
132. Radulovic, J., Sydow, S., and Spiess, J. 1998. J. Neurosci. Res. 54:507-521.
133. Radulovic, M., Dautzenberg, F. M., Sydow, S., Radulovic., J., and Spiess, J. 1999c. J. Immunol. 162:3013-3021.
134. Radulovic, M., Weber, C., and Spiess, J. 2000. J. Neuroimmunol. 103:153-164.
135. Reyes, T., Lewis, K., Kunitake, K., Vaughan, J., Arias, C., Hogenesch, J., Gulyas, J., Rivier, J., Vale, W., and Sawchenko, P. 2001. Proc. Natl. Acad. Sci. USA 98:2843-2848.
136. Richter, R. M., and Mulvany, M. J. 1995. Peptides 16:843-849.
137. Rivier, J., Lahrichi, S. L., Gulyas, J., Erchegyi, J., Koerber, S. C., Craig, A. G., Corrigan, A., Rivier, C., and Vale, W. W. 1998. J. Med. Chem. 41:2614-2620.
138. Rivier, J., Rivier, C., Galyean, R., Miranda, A., Miller, C., Craig, A. G., Yamamoto, G., Brown, M., and Vale, W. W. 1993. J. Med. Chem. 36:2851-2859.
139. Rivier, J., Rivier, C., and Vale, W. W. 1984. Science 224:889-891.
140. Rivier, J. E., Kirby, D. A., Lahrichi, S. L., Corrigan, A., Vale, W. W., and Rivier, C. L. 1999. J. Med. Chem. 42:3175-3182.
141. Romier, C., Bernassau, J., Cambillau, C., and Darbon, H. 1993. Protein Eng. 6:149-156.
142. Ross, P. C., Kostas, C. M., and Ramabhadran, T. V. 1994. Biochem. Biophys. Res. Commun. 205:1836-1842.
143. Rühmann, A., Bonk, I., and Köpke, A. K. E. 1999. Peptides 20:1311-1319.
144. Rühmann, A., Bonk, I., Lin, C. J. R., Rosenfeld, M. G., and Spiess, J. 1998. Proc. Natl. Acad. Sci. USA 95:15264-15269.
145. Sakai, K., Yamada, M., Horiba, N., Wakui, M., Demura, H., and Suda, T. 1998. Gene 219:125-130.
146. Schwartzkroin, P. A., and Stafstrom, C. E. 1980. Science 210:1125-1126.
147. Segre, G. V., and Goldring, S. R. 1993. Trends Endocrinol. Metab. 4:309-314.
148. Singh, V. K., and Leu, S. J. 1993. Immunol. Lett. 35:239-245.
149. Smagin, G. N., Heinrichs, S. C., and Dunn, A. J. 2001. Peptides 22:713-724.
150. Smart, D., Coppel, A., Rossant, C. M. H., and McKnight, A. 1999. Eur. J. Pharmacol. 379:229-235.
151. Smith, E. M., Cadet, P., Stefano, G. B., Opp, M. R., and Hughes, T. K., Jr. 1999. J. Neuroimmunol. 100:140-148.
152. Smith, G., Aubry, J.-M., Dellu, F., Contarino, A., Bilezikjian, L., Gold, L., Chen, R., Marchuk, Y., Hauser, C., Bentley, C., Sawchenko, P., Koob, G., Vale, W., and Lee, K.-F. 1998. Neuron 20:1093-1102.
153. Spiess, J., Dautzenberg, F. M., Sydow, S., Hauger, R. L., Rühmann, A., Blank, T., and Radulovic, J. 1998. Trends Endocrinol. Metab. 9:140-145.
154. Spiess, J., Rivier, J., Rivier, C., and Vale, W. 1981. Proc. Natl. Acad. Sci. USA 78:6517-6521.
155. Spina, M., Basso, A., Zorrilla, E., Heyser, C., Rivier, J., Vale, W., Merlo-Pich, E., and Koob, G. 2000. Neuropsychopharmacol. 22:230-239.
156. Steckler, T., and Holsboer, M. 1999. Biol. Psychiatry 46:1480-1508.
157. Stenzel, P., Kesterson, R., Yeung, W., Cone, R. D., Rittenberg, M. B., and Stenzel-Poore, M. P. 1995. Mol. Endocrinol. 9:637-645.
158. Sternberg, E. M., Hill, J. M., Chrousos, G. P., Kamilaris, T., Listwak, S. J., Gold, P. W., and Wilder, R. L. 1989. Proc. Natl. Acad. Sci. USA 86:2374-2378.
159. Sutton, S. W., Behan, D. P., Lahrichi, S. L., Kaiser, R., Corrigan, A., Lowry, P., Potter, E., Perrin, M. H., Rivier, J., and Vale, W. W. 1995. Endocrinology 136:1097-1102.
160. Swerdlow, N. R., Britton, K. T., and Koob, G. F. 1989. Neuropsychopharmacol. 2:285-292.
161. Takahashi, L. K., Ho, S. P., Livanov, V., Graciani, N., and Arneric, S. P. 2001. Brain Res. 902:135-142.
162. Tazi, A., Dantzer, R., Le Moal, M., Rivier, J., Vale, W. W., and Koob, G.F. 1987. Regul. Pept. 18:37-42.
163. Theoharides, T. C., Singh, L. K., Boucher, W., Pang, X. Z., Letourneau, R., Webster, E., and Chrousos, G. 1998. Endocrinology 139:403-413.
164. Thompson, R. C., Seasholtz, A. F., Douglass, J. O., and Herbert, E. 1990. Cloning and distribution of the rat corticotropin-releasing factor (CRF) gene. In Corticotropin-Releasing Factor: Basic and Clinical Studies of the Neuropeptide, eds. E. B. De Souza and C. B. Nemeroff, 1-12. Boca Raton, FL: CRC Press.
165. Timpl, P., Spanagel, R., Sillaber, I., Kresse, A., Reul, J., Stalla, G. K., Blanquet, V., Steckler, T., Holsboer, F., and Wurst, W. 1998. Nat. Genet. 19:162-166.
166. Torpy, D. J., Webster, E. L., Zachman, E. K., Aguilera, G., and Chrousos, G. P. 1999. Neuroimmunomodulation 6:182-186.
167. Tsagarakis, S., Gillies, G., Rees, L. H., Besser, M., and Grossman, A. 1989. Neuroendocrinol. 49:98-101.
168. Tsai-Morris, C. H., Buczko, E., Geng, Y., Gamboa-Pinto, A., and Dufau, M. L. 1996. J. Biol. Chem. 271:14519-14525.
169. Tsuruda, L. M., Lamperti, E. D., Lewis, S. E., Tolentino, P. J., Dikkes, P., Villakomaroff, L., Ebert, K. M., and Fink, J. S. 1996. Mol. Brain Res. 42:181-192.
170. Turnbull, A. V., Smith, G. W., Lee, S., Vale, W. W., Lee, K. F., and Rivier, C. 1999. Endocrinology 140:1013-1017.
171. Vale, W., Spiess, J., Rivier, C., and Rivier, J. 1981. Science 213:1394-1397.
172. van Pett, K., Viau, V., Bittencourt, J. C., Chan, R. K., Li, H. Y., Arias, C., Prins, G. S., Perrin, M., Vale, W., and Sawchenko, P. E. 2000. J. Comp. Neurol. 428:191-212.
173. Vaughan, J., Donaldson, C., Bittencourt, J., Perrin, M. H., Lewis, K., Sutton, S., Chan, R., Turnbull, A. V., Lovejoy, D., Rivier, C., Rivier, J., Sawchenko, P. E., and Vale, W. W. 1995. Nature 378:287-292.
174. Vita, N., Laurent, P., Lefort, S., Chalon, P., Lelias, J. M., Kaghad, M., Le Fur, G., Caput, D., and Ferrara, P. 1993. FEBS Lett. 335:1-5.
175. Walton, M., Woodgate, A. M., Muravlev, A., Xu, R., During, M. J., and Dragunow, M. 1999. J. Neurochem. 73:1836-1842.
176. Wang, H. L., Tsai, L. Y., and Lee, E. H. 2000. J. Neurophysiol. 83:343-349.
177. Webster, E. L., Lewis, D. B., Torpy, D. J., Zachman, E. K., Rice, K. C., and Chrousos, G. P. 1996. Endocrinology 137:5747-5750.
178. Wei, E. T., Gao, G. C., and Thomas, H. A. 1993. Ciba Foundation Symposium 172:258-268.
179. Wiersma, A., Bohus, B., and Koolhaas, J. M. 1993. Brain Res. 625:219-227.
180. Wilmen, A., Walkenbach, A., Fuller, P., Lankatbuttgereit, B., Goke, R., and Goke, B. 1998. Exp. Clin. Endocrinol. Diab. 106:299-302.
181. Winslow, J. T., Newman, J. D., and Insel, T. R. 1989. Pharmacol. Biochem. & Behav. 32:919-926.
182. Wong, M. L., al-Shekhlee, A., Bongiorno, P. B., Esposito, A., Khatri, P., Sternberg, E. M., Gold, P. W., and Licinio, J. 1996. Mol. Psychiatry 1:307-312.
183. Yu, B., and Shinnick-Gallagher, P. 1998. J. Pharmacol. Exp. Ther. 284:170-179.
184. Zorrilla, E. P., Schulteis, G., Ling, N., Koob, G. F., and De Souza, E. B. 2001. Neuroreport 12:1231-1234.