Differential effects of IL-10 on prostaglandin H synthase-2 expression and prostaglandin E2 biosynthesis between spleen and bone marrow macrophages

Journal of Leukocyte Biology

Volumn 77, Issue 4, 2005, Pages 544-551

  Shibata, Yoshimi ^a   Nishiyama, Akihito ^a   Ohata, Hiroyoshi ^a   Gabbard, Jon ^a   Myrvik, Quentin N ^c   Henriksen, Ruth Ann ^b  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c Myrvik Enterprises   (United States)

Author keywords

LPS; Marrow macrophages; PGE2; PGHS 2; Splenic macrophages

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 10; PROSTAGLANDIN E2; PROSTAGLANDIN H SYNTHASE 2; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; FEMALE; INFLAMMATION; MACROPHAGE; MONONUCLEAR PHAGOCYTE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SPLEEN CELL;

ANIMALS; ARACHIDONIC ACID; BONE MARROW CELLS; CALCIMYCIN; CYCLOOXYGENASE 2; DINOPROSTONE; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SPLEEN;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 16844367805     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0504311     Document Type: Article

References (48)

1. Dubois, R. N., Abramson, S. B., Crofford, L., Gupta, R. A., Simon, L. S., Van De Putte, L. B., Lipsky, P. E. (1998) Cyclooxygenase in biology and disease. FASEB J. 12, 1063-1073.
2. Shibata, Y., Volkman, A. (1985) The effect of bone marrow depletion on prostaglandin E producing suppressor macrophages in mouse spleen. J. Immunol. 135, 3897-3904.
3. 89Sr. Am. J. Pathol. 127, 75-82.
4. Rocca, B., Spain, L. M., Pure, E., Langenbach, R., Patrono, C., Fitzgerald, G. A. (1999) Distinct roles of prostaglandin H synthase 1 and 2 in T-cell development. J. Clin. Invest. 103, 1469-1477.
5. Fitzgerald, T. J. (1992) The Th1/Th2 switch in syphilitic infection: is it detrimental? Infect. Immun. 60, 3475-3479.
6. 89Sr-treated mice with bone marrow from Corynebacterium parvum primed donors. Reg. Immunol. 2, 169-175.
7. Druker, B. J., Wepsic, H. T. (1983) BCG-induced macrophages as suppressor cells. Cancer Invest. 1, 151-161.
8. Berg, D. J., Zhang, J., Lauricella, D. M., Moore, S. A. (2001) IL-10 is a central regulator of cyclooxygenase-2 expression and prostaglandin production. J. Immunol. 166, 2674-2680.
9. 2 production and its suppressive role in Th1 activation in Th2-dominant Balb/c mice. J. Immunol. 170, 757-764.
10. Smith, W. L., Garavito, R. M., DeWitt, D. L. (1996) Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J. Biol. Chem. 271, 33157-33160.
11. Endo, T., Ogushi, F., Sone, S. (1996) LPS-dependent cyclooxygenase-2 induction in human monocytes is down-regulated by IL-13, but not by IFN-γ. J. Immunol. 156, 2240-2246.
12. Lee, S. H., Soyoola, E., Chanmugam, P., Hart, S., Zhong, H., Liou, S., Simmons, D., Hwang, D. (1992) Selective expression of mitogen-inducible cyclooxygenase in macrophages with lipopolysaccharide. J. Biol. Chem. 267, 25934-25938.
13. Giroux, M., Descoteaux, A. (2000) Cyclooxygenase-2 expression in macrophages: modulation by protein kinase C-α. J. Immunol. 165, 3985-3991.
14. O'Sullivan, M. G., Muggins Jr., E. M., Meade, E. A., DeWitt, D. L., McCall, C. E. (1992) Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages. Biochem. Biophys. Res. Commun. 187, 1123-1127.
15. Vlahos, R., Stewart, A. G. (1999) Interleukin-1α and tumour necrosis factor-α modulate airway smooth muscle DNA synthesis by induction of cyclo-oxygenase-2: inhibition by dexamethasone and fluticasone propionate. Br. J. Pharmacol. 126, 1315-1324.
16. Huang, Z. F., Massey, J. B., Via, D. P. (2000) Differential regulation of cyclooxygenase-2 (COX-2) mRNA stability by interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in human in vitro differentiated macrophages. Biochem. Pharmacol. 59, 187-194.
17. 2 production by IFN-γ in human macrophages. J. Immunol. 161, 2441-2448.
18. Matsuura, H., Sakaue, M., Subbaramaiah, K., Kamitani, H., Eling, T. E., Dannenberg, A. J., Tanabe, T., Inoue, H., Arata, J., Jetten, A. M. (1999) Regulation of cyclooxygenase-2 by interferon γ and transforming growth factor α in normal human epidermal keratinocytes and squamous carcinoma cells: role of mitogen-activated protein kinases. J. Biol. Chem. 274, 29138-29148.
19. Niiro, H., Otsuka, T., Izuhara, K., Yamaoka, K., Ohshima, K., Tanabe, T., Hara, S., Nemoto, Y., Tanaka, Y., Nakashima, H., Niho, Y. (1997) Regulation by interleukin-10 and interleukin-4 of cyclooxygenase-2 expression in human neutrophils. Blood 89, 1621-1628.
20. Diaz-Cazorla, M., Perez-Sala, D., Ros, J., Jimenez, W., Fresno, M., Lamas, S. (1999) Regulation of cyclooxygenase-2 expression in human mesangial cells: transcriptional inhibition by IL-13. Eur. J. Biochem. 260, 268-274.
21. Alaaeddine, N., Di Battista, J. A., Pelletier, J. P., Kiansa, K., Cloutier, J. M., Martel-Pelletier, J. (1999) Inhibition of tumor necrosis factor α-induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: distinct targeting in the signaling pathways. Arthritis Rheum. 42, 710-718.
22. Niiro, H., Otsuka, T., Tanabe, T., Hara, S., Kuga, S., Nemoto, Y., Tanaka, Y., Nakashima, H., Kitajima, S., Abe, M. (1995) Inhibition by interleukin-10 of inducible cyclooxygenase expression in lipopolysaccharide- stimulated monocytes: its underlying mechanism in comparison with interleukin-4. Blood 85, 3736-3745.
23. Reddy, S. T., Gilbert, R. S., Xie, W., Luner, S., Herschman, H. R. (1994) TGF-β 1 inhibits both endotoxin-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene in murine macrophages. J. Leukoc. Biol. 55, 192-200.
24. de Waal-Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G., de Vries, J. E. (1991) Interleukin-10 inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174, 1209-1220.
25. Fiorentino, D. F., Zlotnik, A., Mosmann, T. R., Howard, M., O'Garra, A. (1991) IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147, 3815-3822.
26. Shibata, Y., Foster, L. A., Kurimoto, M., Okamura, H., Nakamura, R. M., Kawajiri, K., Justice, J. P., Van Scott, M. R., Myrvik, Q. N., Metzger, W. J. (1998) Immunoregulatory roles of IL-10 in innate immunity-IL-10 inhibits macrophage production of IFN-γ-inducing factors, but enhances NK cell production of IFN-γ. J. Immunol. 161, 4283-4288.
27. 2. Blood 83, 3316-3323.
28. 2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo. J. Exp. Med. 184, 883-891.
29. 2 is a potent inhibitor of human interleukin 12 production. J. Exp. Med. 181, 775-779.
30. 2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness. J. Immunol. 161, 2723-2730.
31. 2, promote type 2 cytokine production in maturing human naive T helper cells. J. Immunol. 159, 28-35.
32. 2. J. Biol. Chem. 267, 9443-9449.
33. 2 protects against liver injury after Escherichia coli infection but hampers the resolution of the infection in mice. J. Immunol. 161, 3019-3025.
34. Humes, J. L., Bonney, R. J., Pelus, L., Dahlgren, M. E., Sadowski, S. J., Kuehl Jr., F. A., Davies, P. (1977) Macrophages synthesize and release prostaglandins in response to inflammatory stimuli. Nature 269, 149-151.
35. 2 gene in inbred mouse strains. J. Biol. Chem. 270, 22378-22385.
36. Shibata, Y., Honda, L, Justice, J. P., Van Scott, M. R., Nakamura, R. M., Myrvik, Q. N. (2001) Th1 adjuvant N-acetyl-D-glucosamine polymer up-regulates Th1 immunity but down-regulates Th2 immunity against a mycobacterial protein (MPB-59) in interleukin-10-knockout and wild-type mice. Infect. Immun. 69, 6123-6130.
37. Blanco, J. C., Contrusi, C., Salkowski, C. A., Dewitt, D. L., Ozato, K., Vogel, S. N. (2000) Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon γ-dependent cyclooxygenase 2 expression. J. Exp. Med. 191, 2131-2144.
38. Ohmori, Y., Hamilton, T. A. (2001) Requirement for STAT1 in LPS-induced gene expression in macrophages. J. Leukoc. Biol. 69, 598-604.
39. Chandrasekharan, N. V., Dai, H., Roos, K. L., Evanson, N. K., Tomsik, J., Elton, T. S., Simmons, D. L. (2002) COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc. Natl. Acad. Sci. USA 99, 13926-13931.
40. Barrios-Rodiles, M., Tiraloche, G., Chadee, K. (1999) Lipopolysaccharide modulates cyclooxygenase-2 transcriptionally and posttranscriptionally in human macrophages independently from endogenous IL-1β and TNF-α. J. Immunol. 163, 963-969.
41. Pouliot, M., Baillargeon, J., Lee, J. C., Cleland, L. G., James, M. J. (1997) Inhibition of prostaglandin endoperoxide synthase-2 expression in stimulated human monocytes. by inhibitors of p38 mitogen-activated protein kinase. J. Immunol. 158, 4930-4937.
42. Ridley, S. H, Sarsfield, S. J., Lee, J. C., Bigg, H. F., Cawston, T. E., Taylor, D. J., DeWitt, D. L., Saklatvala, J. (1997) Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels. J. Immunol. 158, 3165-3173.
43. Niiro, H., Otsuka, T., Ogami, E., Yamaoka, K., Nagano, S., Akahoshi, M., Nakashima, H., Arinobu, Y., Izuhara, K., Niho, Y. (1998) MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes. Biochem. Biophys. Res. Commun. 250, 200-205.
44. Dean, J. L., Brook, M., Clark, A. R., Saklatvala, J. (1999) p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J. Biol. Chem. 274, 264-269.
45. Nagano, S., Otsuka, T., Niiro, H., Yamaoka, K., Arinobu, Y., Ogami, E., Akahoshi, M., Inoue, Y., Miyake, K., Nakashima, H., Niho, Y., Harada, M. (2002) Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines. Int. Immunol. 14, 733-740.
46. Kontoyiannis, D., Kotlyarov, A., Carballo, E., Alexopoulou, L., Blackshear, P. J., Gaestel, M., Davis, R., Flavell, R., Kollias, G. (2001) Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. EMBO J. 20, 3760-3770.
47. Inoue, Y., Otsuka, T., Niiro, H., Nagano, S., Arinobu, Y., Ogami, E., Akahoshi, M., Miyake, K., Ninomiya, L, Shimizu, S., Nakashima, H., Harada, M. (2004) Novel regulatory mechanisms of CD40-induced prostanoid synthesis by IL-4 and IL-10 in human monocytes. J. Immunol. 172, 2147-2154.
48. Nick, J. A., Avdi, N. J., Young, S. K., Lehman, L. A., McDonald, P. P., Frasch, S. C., Billstrom, M. A., Henson, P. M., Johnson, G. L., Worthen, G. S. (1999) Selective activation and functional significance of p38 α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils. J. Clin. Invest. 103, 851-858.