Interleukin-1α and tumour necrosis factor-α modulate airway smooth muscle DNA synthesis by induction of cyclo-oxygenase-2: Inhibition by dexamethasone and fluticasone propionate

British Journal of Pharmacology

Volumn 126, Issue 6, 1999, Pages 1315-1324

  Vlahos, Ross ^a   Stewart, Alastair G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Asthma; Cytokines; Dexamethasone; Glucocorticoids; Human airway smooth muscle; Interleukin 1 ; Tumour necrosis factor

Indexed keywords

6 (2,4 DIFLUOROPHENYLTHIO) 5 METHANESULFONAMIDO 1 INDANONE; BASIC FIBROBLAST GROWTH FACTOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYTOKINE; DEXAMETHASONE; DNA; FLUTICASONE PROPIONATE; INDOMETACIN; INTERLEUKIN 1ALPHA; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; THROMBIN; TUMOR NECROSIS FACTOR ALPHA; ANDROSTANE DERIVATIVE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 1; DIAGNOSTIC AGENT; FLUTICASONE; GLUCOCORTICOID; ICOSANOID; INDAN DERIVATIVE; INTERLEUKIN 1; ISOENZYME; MEMBRANE PROTEIN; MITOGENIC AGENT; PROSTAGLANDIN SYNTHASE; PTGS1 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; THYMIDINE; TRITIUM;

ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; ENZYME INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; TRACHEA MUSCLE; WESTERN BLOTTING; BIOSYNTHESIS; BRONCHUS; CELL CULTURE; CYTOLOGY; DRUG EFFECT; METABOLISM; SMOOTH MUSCLE; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANDROSTADIENES; ANTI-INFLAMMATORY AGENTS; BRONCHI; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINES; DEXAMETHASONE; DNA; EICOSANOIDS; ENZYME INDUCTION; GLUCOCORTICOIDS; HUMANS; INDANS; INTERLEUKIN-1; ISOENZYMES; MEMBRANE PROTEINS; MITOGENS; MUSCLE, SMOOTH; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; THYMIDINE; TRITIUM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032589046     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702424     Document Type: Article

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