Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: Involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines

International Immunology

Volumn 14, Issue 7, 2002, Pages 733-740

  Nagano, Shuji ^a   Otsuka, Takeshi ^a   Niiro, Hiroaki ^a   Yamaoka, Kunihiro ^a   Arinobu, Yojirou ^a   Ogami, Eiichi ^a   Akahoshi, Mitsuteru ^a   Inoue, Yasushi ^a   Miyake, Katsuhisa ^a   Nakashima, Hitoshi ^a   Niho, Yoshiyuki ^a   Harada, Mine ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Extracellular signal regulated protein kinase; IL 10; IL 4; In vitro kinase assay; Mitogen activated protein kinase phosphorylation; p38MAPK; Prostaglandin E2

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLOOXYGENASE 2; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROSTAGLANDIN E2; PROSTANOID; SYNAPTOPHYSIN; ENZYME INHIBITOR; FLAVONOID; IMIDAZOLE DERIVATIVE; ISOENZYME; MEMBRANE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN; PYRIDINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; MOLECULAR BIOLOGY; NEUTROPHIL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; TIME; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; FLAVONOIDS; HUMANS; IMIDAZOLES; INTERLEUKIN-10; INTERLEUKIN-4; ISOENZYMES; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHILS; PHOSPHORYLATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRIDINES; SIGNAL TRANSDUCTION;

EID: 0036319353     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxf038     Document Type: Article

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