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Volumn 92, Issue 4, 2004, Pages 664-678

Inactivating Pit-1 mutations alter subnuclear dynamics suggesting a protein misfolding and nuclear stress response

Author keywords

Cell stress; Chromatin; Photobleaching chaperone; Protein folding; Transcription; Ubiquitin

Indexed keywords

HEAT SHOCK PROTEIN 70; TRANSCRIPTION FACTOR PIT 1; DNA BINDING PROTEIN; GREEN FLUORESCENT PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR; HOMEODOMAIN PROTEIN; POU1F1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 16644382499     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20028     Document Type: Article
Times cited : (8)

References (51)
  • 1
    • 0028126819 scopus 로고
    • Pit-1 determines cell types during development of the anterior pituitary gland. A model for transcriptional regulation of cell phenotypes in mammalian organogenesis
    • Andersen B, Rosenfeld MG. 1994. Pit-1 determines cell types during development of the anterior pituitary gland. A model for transcriptional regulation of cell phenotypes in mammalian organogenesis. J Biol Chem 269:29335-29338.
    • (1994) J Biol Chem , vol.269 , pp. 29335-29338
    • Andersen, B.1    Rosenfeld, M.G.2
  • 2
    • 0035117485 scopus 로고    scopus 로고
    • POU domain factors in the neuroendocrine system: Lessons from developmental biology provide insights into human disease
    • Andersen B, Rosenfeld MG. 2001. POU domain factors in the neuroendocrine system: Lessons from developmental biology provide insights into human disease. Endocr Rev 22:2-35.
    • (2001) Endocr Rev , vol.22 , pp. 2-35
    • Andersen, B.1    Rosenfeld, M.G.2
  • 3
    • 0029785328 scopus 로고    scopus 로고
    • GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element
    • Bradford AP, Conrad KE, Tran PH, Ostrowski MC, Gutierrez-Hartmann A. 1996. GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element. J Biol Chem 271:24639-24648.
    • (1996) J Biol Chem , vol.271 , pp. 24639-24648
    • Bradford, A.P.1    Conrad, K.E.2    Tran, P.H.3    Ostrowski, M.C.4    Gutierrez-Hartmann, A.5
  • 4
    • 0031037986 scopus 로고    scopus 로고
    • Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression
    • Bradford AP, Wasylyk C, Wasylyk B, Gutierrez-Hartmann A. 1997. Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression. Mol Cell Biol 17:1065-1074.
    • (1997) Mol Cell Biol , vol.17 , pp. 1065-1074
    • Bradford, A.P.1    Wasylyk, C.2    Wasylyk, B.3    Gutierrez-Hartmann, A.4
  • 5
    • 0034603162 scopus 로고    scopus 로고
    • The Pit-1 homeodomain and β-domain interact with Ets-1 and modulate synergistic activation of the rat prolactin promoter
    • Bradford AP, Brodsky KS, Diamond SE, Kuhn LC, Liu Y, Gutierrez-Hartmann A. 2000. The Pit-1 homeodomain and β-domain interact with Ets-1 and modulate synergistic activation of the rat prolactin promoter. J Biol Chem 275:3100-3106.
    • (2000) J Biol Chem , vol.275 , pp. 3100-3106
    • Bradford, A.P.1    Brodsky, K.S.2    Diamond, S.E.3    Kuhn, L.C.4    Liu, Y.5    Gutierrez-Hartmann, A.6
  • 7
    • 0031443870 scopus 로고    scopus 로고
    • Activities in Pit-1 determine whether receptor interacting protein 140 activates or inhibits Pit-1/nuclear receptor transcriptional synergy
    • Chuang FM, West BL, Baxter JD, Schaufele F. 1997. Activities in Pit-1 determine whether receptor interacting protein 140 activates or inhibits Pit-1/nuclear receptor transcriptional synergy. Mol Endocrinol 11: 1332-1341.
    • (1997) Mol Endocrinol , vol.11 , pp. 1332-1341
    • Chuang, F.M.1    West, B.L.2    Baxter, J.D.3    Schaufele, F.4
  • 8
    • 0029835520 scopus 로고    scopus 로고
    • Role of Pit-1 in the gene expression of growth hormone, prolactin, and thyrotropin
    • Cohen LE, Wondisford FE, Radovick S. 1996. Role of Pit-1 in the gene expression of growth hormone, prolactin, and thyrotropin. Endocrinol Metab Clin North Am 25:523-540.
    • (1996) Endocrinol Metab Clin North Am , vol.25 , pp. 523-540
    • Cohen, L.E.1    Wondisford, F.E.2    Radovick, S.3
  • 9
    • 0031467707 scopus 로고    scopus 로고
    • HSF1 granules: A novel stress-induced nuclear compartment of human cells
    • Cotto J, Fox S, Morimoto R. 1997. HSF1 granules: A novel stress-induced nuclear compartment of human cells. J Cell Sci 110(Pt 23):2925-2934.
    • (1997) J Cell Sci , vol.110 , Issue.PART 23 , pp. 2925-2934
    • Cotto, J.1    Fox, S.2    Morimoto, R.3
  • 10
    • 0031838352 scopus 로고    scopus 로고
    • Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
    • Cummings CJ, Mancini MA, Antalffy B, DeFranco DB, Orr HT, Zoghbi HY. 1998. Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat Genet 19:148-154.
    • (1998) Nat Genet , vol.19 , pp. 148-154
    • Cummings, C.J.1    Mancini, M.A.2    Antalffy, B.3    Defranco, D.B.4    Orr, H.T.5    Zoghbi, H.Y.6
  • 12
    • 0032846735 scopus 로고    scopus 로고
    • Combinatorial codes in signaling and synergy: Lessons from pituitary development
    • Dasen JS, Rosenfeld MG. 1999. Combinatorial codes in signaling and synergy: Lessons from pituitary development. Curr Opin Genet Dev 9:566-574.
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 566-574
    • Dasen, J.S.1    Rosenfeld, M.G.2
  • 14
    • 0032161918 scopus 로고    scopus 로고
    • Visualization of Pit-1 transcription factor interactions in the living cell nucleus by fluorescence resonance energy transfer microscopy
    • Day RN. 1998. Visualization of Pit-1 transcription factor interactions in the living cell nucleus by fluorescence resonance energy transfer microscopy. Mol Endocrinol 12:1410-1419.
    • (1998) Mol Endocrinol , vol.12 , pp. 1410-1419
    • Day, R.N.1
  • 15
    • 0025671979 scopus 로고
    • Both Pit-1 and the estrogen receptor are required for estrogen responsiveness of the rat prolactin gene
    • Day RN, Koike S, Sakai M, Muramatsu M, Maurer RA. 1990. Both Pit-1 and the estrogen receptor are required for estrogen responsiveness of the rat prolactin gene. Mol Endocrinol 4:1964-1971.
    • (1990) Mol Endocrinol , vol.4 , pp. 1964-1971
    • Day, R.N.1    Koike, S.2    Sakai, M.3    Muramatsu, M.4    Maurer, R.A.5
  • 16
    • 0026378298 scopus 로고
    • The tissue-specific mammalian transcription factor, Pit-1, activates transcription in Saccharomyces cerevisiae
    • Ding Y, Lu W, Roberson MS, Moye-Rowley WS, Maurer RA. 1991. The tissue-specific mammalian transcription factor, Pit-1, activates transcription in Saccharomyces cerevisiae. Mol Endocrinol 5:1239-1245.
    • (1991) Mol Endocrinol , vol.5 , pp. 1239-1245
    • Ding, Y.1    Lu, W.2    Roberson, M.S.3    Moye-Rowley, W.S.4    Maurer, R.A.5
  • 18
    • 0032816849 scopus 로고    scopus 로고
    • Establishment of an estrogen responsive rat pituitary cell sub-line MtT/E-2
    • Fujimoto N, Maruyama S, Ito A. 1999. Establishment of an estrogen responsive rat pituitary cell sub-line MtT/E-2. Endocr J 46:389-396.
    • (1999) Endocr J , vol.46 , pp. 389-396
    • Fujimoto, N.1    Maruyama, S.2    Ito, A.3
  • 19
    • 0029113026 scopus 로고
    • Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain
    • Holloway JM, Szeto DP, Scully KM, Glass CK, Rosenfeld MG. 1995. Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain. Genes Dev 9:1992-2006.
    • (1995) Genes Dev , vol.9 , pp. 1992-2006
    • Holloway, J.M.1    Szeto, D.P.2    Scully, K.M.3    Glass, C.K.4    Rosenfeld, M.G.5
  • 20
    • 0029151923 scopus 로고
    • A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways
    • Howard PW, Maurer RA. 1995. A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways. J Biol Chem 270:20930-20936.
    • (1995) J Biol Chem , vol.270 , pp. 20930-20936
    • Howard, P.W.1    Maurer, R.A.2
  • 23
    • 0344359766 scopus 로고    scopus 로고
    • A model for the development of the hypothalamic-pituitary axis: Transcribing the hypophysis
    • Kioussi C, Carriere C, Rosenfeld MG. 1999. A model for the development of the hypothalamic-pituitary axis: Transcribing the hypophysis. Mech Dev 81:23-35.
    • (1999) Mech Dev , vol.81 , pp. 23-35
    • Kioussi, C.1    Carriere, C.2    Rosenfeld, M.G.3
  • 24
    • 0034652127 scopus 로고    scopus 로고
    • Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins
    • Krobitsch S, Lindquist S. 2000. Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins. Proc Natl Acad Sci USA 97:1589-1594.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1589-1594
    • Krobitsch, S.1    Lindquist, S.2
  • 25
    • 0025014024 scopus 로고
    • Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1
    • Li S, Crenshaw EBd, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG. 1990. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature 347:528-533.
    • (1990) Nature , vol.347 , pp. 528-533
    • Li, S.1    Crenshaw, E.Bd.2    Rawson, E.J.3    Simmons, D.M.4    Swanson, L.W.5    Rosenfeld, M.G.6
  • 26
    • 0028793120 scopus 로고
    • In vivo mutational analysis of the DNA binding domain of the tissue-specific transcription factor, Pit-1
    • Liang J, Moye-Rowley S, Maurer RA. 1995. In vivo mutational analysis of the DNA binding domain of the tissue-specific transcription factor, Pit-1. J Biol Chem 270:25520-25525.
    • (1995) J Biol Chem , vol.270 , pp. 25520-25525
    • Liang, J.1    Moye-Rowley, S.2    Maurer, R.A.3
  • 27
    • 0033230850 scopus 로고    scopus 로고
    • Expanding our understanding of polyglutamine diseases through mouse models
    • Lin X, Cummings CJ, Zoghbi HY. 1999. Expanding our understanding of polyglutamine diseases through mouse models. Neuron 24:499-502.
    • (1999) Neuron , vol.24 , pp. 499-502
    • Lin, X.1    Cummings, C.J.2    Zoghbi, H.Y.3
  • 28
    • 0033103263 scopus 로고    scopus 로고
    • Subnuclear partitioning and functional regulation of the Pit-1 transcription factor
    • Mancini MG, Liu B, Sharp ZD, Mancini MA. 1999. Subnuclear partitioning and functional regulation of the Pit-1 transcription factor. J Cell Biochem 72:322-338.
    • (1999) J Cell Biochem , vol.72 , pp. 322-338
    • Mancini, M.G.1    Liu, B.2    Sharp, Z.D.3    Mancini, M.A.4
  • 29
    • 0343415609 scopus 로고    scopus 로고
    • The glucocorticoid receptor: Rapid exchange with regulatory sites in living cells
    • McNally JG, Muller WG, Walker D, Wolford R, Hager GL. 2000. The glucocorticoid receptor: Rapid exchange with regulatory sites in living cells. Science 287:1262-1265.
    • (2000) Science , vol.287 , pp. 1262-1265
    • McNally, J.G.1    Muller, W.G.2    Walker, D.3    Wolford, R.4    Hager, G.L.5
  • 30
    • 0037099046 scopus 로고    scopus 로고
    • Chaperoning signaling pathways: Molecular chaperones as stress-sensing 'heat shock' proteins
    • Nollen EA, Morimoto RI. 2002. Chaperoning signaling pathways: Molecular chaperones as stress-sensing 'heat shock' proteins. J Cell Sci 115:2809-2816.
    • (2002) J Cell Sci , vol.115 , pp. 2809-2816
    • Nollen, E.A.1    Morimoto, R.I.2
  • 33
    • 0034611785 scopus 로고    scopus 로고
    • High mobility of proteins in the mammalian cell nucleus
    • Phair RD, Misteli T. 2000. High mobility of proteins in the mammalian cell nucleus. Nature 404:604-609.
    • (2000) Nature , vol.404 , pp. 604-609
    • Phair, R.D.1    Misteli, T.2
  • 36
    • 0033304629 scopus 로고    scopus 로고
    • Regulation of estrogen receptor activation of the prolactin enhancer/promoter by antagonistic activation function-2-interacting proteins
    • Schaufele F. 1999. Regulation of estrogen receptor activation of the prolactin enhancer/promoter by antagonistic activation function-2-interacting proteins. Mol Endocrinol 13:935-945.
    • (1999) Mol Endocrinol , vol.13 , pp. 935-945
    • Schaufele, F.1
  • 38
    • 0037155604 scopus 로고    scopus 로고
    • Pituitary development: Regulatory codes in mammalian organogenesis
    • Scully KM, Rosenfeld MG. 2002. Pituitary development: Regulatory codes in mammalian organogenesis. Science 295:2231-2235.
    • (2002) Science , vol.295 , pp. 2231-2235
    • Scully, K.M.1    Rosenfeld, M.G.2
  • 40
    • 0028843135 scopus 로고
    • Rat Pit-1 stimulates transcription in vitro by influencing pre-initiation complex assembly
    • Sharp ZD. 1995. Rat Pit-1 stimulates transcription in vitro by influencing pre-initiation complex assembly. Biochem Biophys Res Commun 206:40-45.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 40-45
    • Sharp, Z.D.1
  • 41
    • 0034098057 scopus 로고    scopus 로고
    • Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract
    • Simeoni S, Mancini MA, Stenoien DL, Marcelli M, Weigel NL, Zanisi M, Martini L, Poletti A. 2000. Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract. Hum Mol Genet 9:133-144.
    • (2000) Hum Mol Genet , vol.9 , pp. 133-144
    • Simeoni, S.1    Mancini, M.A.2    Stenoien, D.L.3    Marcelli, M.4    Weigel, N.L.5    Zanisi, M.6    Martini, L.7    Poletti, A.8
  • 42
    • 0025286831 scopus 로고
    • Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors
    • Simmons DM, Voss JW, Ingraham HA, Holloway JM, Broide RS, Rosenfeld MG, Swanson LW. 1990. Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev 4:695-711.
    • (1990) Genes Dev , vol.4 , pp. 695-711
    • Simmons, D.M.1    Voss, J.W.2    Ingraham, H.A.3    Holloway, J.M.4    Broide, R.S.5    Rosenfeld, M.G.6    Swanson, L.W.7
  • 43
    • 0028904804 scopus 로고
    • Pit-1 exhibits a unique promoter spacing requirement for activation and synergism
    • Smith KP, Liu B, Scott C, Sharp ZD. 1995. Pit-1 exhibits a unique promoter spacing requirement for activation and synergism. J Biol Chem 270:4484-4491.
    • (1995) J Biol Chem , vol.270 , pp. 4484-4491
    • Smith, K.P.1    Liu, B.2    Scott, C.3    Sharp, Z.D.4
  • 44
    • 0032945938 scopus 로고    scopus 로고
    • Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone
    • Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA. 1999. Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum Mol Genet 8:731-741.
    • (1999) Hum Mol Genet , vol.8 , pp. 731-741
    • Stenoien, D.L.1    Cummings, C.J.2    Adams, H.P.3    Mancini, M.G.4    Patel, K.5    Demartino, G.N.6    Marcelli, M.7    Weigel, N.L.8    Mancini, M.A.9
  • 48
    • 0036798685 scopus 로고    scopus 로고
    • Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components
    • Stenoien DL, Mielke M, Mancini MA. 2002. Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components. Nat Cell Biol 4:806-810.
    • (2002) Nat Cell Biol , vol.4 , pp. 806-810
    • Stenoien, D.L.1    Mielke, M.2    Mancini, M.A.3
  • 49
    • 0027733628 scopus 로고
    • Transcriptional control of GH expression and anterior pituitary development
    • Theill LE, Karin M. 1993. Transcriptional control of GH expression and anterior pituitary development. Endocr Rev 14:670-689.
    • (1993) Endocr Rev , vol.14 , pp. 670-689
    • Theill, L.E.1    Karin, M.2
  • 50
    • 0030560899 scopus 로고    scopus 로고
    • The hypothalamic-pituitary axis: Co-development of two organs
    • Treier M, Rosenfeld MG. 1996. The hypothalamic-pituitary axis: Co-development of two organs. Curr Opin Cell Biol 8:833-843.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 833-843
    • Treier, M.1    Rosenfeld, M.G.2


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