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Volumn 8, Issue 6, 1996, Pages 833-843

The hypothalamic-pituitary axis: Co-development of two organs

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; FOLLITROPIN; HOMEODOMAIN PROTEIN; HORMONE; TRANSCRIPTION FACTOR;

EID: 0030560899     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(96)80085-8     Document Type: Article
Times cited : (130)

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    • of outstanding interest. This paper, together with [81], describes the phenotype of mice with a deletion of the Brn-2 genomic locus. Lack of Brn-2 results in loss of endocrine hypothalamic nuclei and the posterior pituitary gland. This finding demonstrates that the developmental program of the endocrine hypothalamus, like that of the anterior pituitary gland, seems, at least in part, to be directed by a POU domain transcription factor. This transcription factor is Brn-2 in the endocrine hypothalamus and Pit-1 in the anterior pituitary gland.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.