-
1
-
-
0033893119
-
In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin⧸IL-3 fusion protein
-
R.L. Alexander G.L. Kucera B. Klein A.E. Frankel In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin⧸IL-3 fusion protein Bioconj. Chem 11 2000 564 568
-
(2000)
Bioconj. Chem
, vol.11
, pp. 564-568
-
-
Alexander, R.L.1
Kucera, G.L.2
Klein, B.3
Frankel, A.E.4
-
2
-
-
0027374447
-
A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy
-
P.L. Amlot M.J. Stone D. Cunningham J. Fay J. Newman R. Collins R. May M. McCarthy J. Richardson V. Ghetie A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy Blood 82 1993 2624 2633
-
(1993)
Blood
, vol.82
, pp. 2624-2633
-
-
Amlot, P.L.1
Stone, M.J.2
Cunningham, D.3
Fay, J.4
Newman, J.5
Collins, R.6
May, R.7
McCarthy, M.8
Richardson, J.9
Ghetie, V.10
-
3
-
-
0035958878
-
Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells
-
S.F. Atkinson T. Bettinger L.W. Seymour J.P. Behr C.M. Ward Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells J. Biol. Chem 276 2001 27930 27935
-
(2001)
J. Biol. Chem
, vol.276
, pp. 27930-27935
-
-
Atkinson, S.F.1
Bettinger, T.2
Seymour, L.W.3
Behr, J.P.4
Ward, C.M.5
-
4
-
-
0032943931
-
An in vivo model to study immunotoxin-induced vascular leak in human tissue
-
R. Baluna E.S. Vitetta An in vivo model to study immunotoxin-induced vascular leak in human tissue J. Immunother 22 1999 41 47
-
(1999)
J. Immunother
, vol.22
, pp. 41-47
-
-
Baluna, R.1
Vitetta, E.S.2
-
5
-
-
0030913706
-
A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor
-
A.E. Bendel Y. Shao S.M. Davies B. Warman C.H. Yang K.G. Waddick F.M. Uckun J.P. Perentesis A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor Leuk. Lymph 25 1997 257 270
-
(1997)
Leuk. Lymph
, vol.25
, pp. 257-270
-
-
Bendel, A.E.1
Shao, Y.2
Davies, S.M.3
Warman, B.4
Yang, C.H.5
Waddick, K.G.6
Uckun, F.M.7
Perentesis, J.P.8
-
6
-
-
0029903272
-
Saporin, a ribosome-inactivating protein used to prepare immunotoxins, induces cell death via apoptosis
-
G. Bérgamaschi V. Perfetti L. Tonon A. Novella C. Lucotti M. Danova M. Glennie G. Merlini M. Cazzola Saporin, a ribosome-inactivating protein used to prepare immunotoxins, induces cell death via apoptosis Br. J. Haematol 93 1996 789 794
-
(1996)
Br. J. Haematol
, vol.93
, pp. 789-794
-
-
Bérgamaschi, G.1
Perfetti, V.2
Tonon, L.3
Novella, A.4
Lucotti, C.5
Danova, M.6
Glennie, M.7
Merlini, G.8
Cazzola, M.9
-
7
-
-
0036224208
-
CD33 as a target for selective ablation of acute myeloid leukemia
-
I.D. Bernstein CD33 as a target for selective ablation of acute myeloid leukemia Clin. Lymph 2 Suppl. 1 2002 S9 S11
-
(2002)
Clin. Lymph
, vol.2
, Issue.Suppl. 1
, pp. S9-S11
-
-
Bernstein, I.D.1
-
8
-
-
0033840526
-
In vitro anti-tumour activity of anti-CD80 and anti-CD86 immunotoxins containing type 1 ribosome-inactivating proteins
-
A. Bolognesi L. Polito P.L. Tazzari R.M. Lemoli C. Lubelli M. Fogli L. Boon M. de-Boer F. Stirpe In vitro anti-tumour activity of anti-CD80 and anti-CD86 immunotoxins containing type 1 ribosome-inactivating proteins Br. J. Haematol 110 2000 351 361
-
(2000)
Br. J. Haematol
, vol.110
, pp. 351-361
-
-
Bolognesi, A.1
Polito, L.2
Tazzari, P.L.3
Lemoli, R.M.4
Lubelli, C.5
Fogli, M.6
Boon, L.7
de-Boer, M.8
Stirpe, F.9
-
9
-
-
0027185186
-
Delivery of saporin to human B-cell lymphoma using bispecific antibody: Targeting via CD22 but not CD19, CD37, or immunoglobulin results in efficient killing
-
M.A. Bonardi R.R. French P. Amlot G. Gromo D. Modena M.J. Glennie Delivery of saporin to human B-cell lymphoma using bispecific antibody: Targeting via CD22 but not CD19, CD37, or immunoglobulin results in efficient killing Cancer Res 53 1993 3015 3021
-
(1993)
Cancer Res
, vol.53
, pp. 3015-3021
-
-
Bonardi, M.A.1
French, R.R.2
Amlot, P.3
Gromo, G.4
Modena, D.5
Glennie, M.J.6
-
10
-
-
0024502004
-
B-cell restricted saporin immunotoxins: Activity against B-cell lines and chronic lymphocytic leukemia cells
-
M. Bregni S. Siena A. Formosa D.A. Lappi D. Martineau F. Malavasi B. Dorken G. Bonadonna A.M. Gianni B-cell restricted saporin immunotoxins: Activity against B-cell lines and chronic lymphocytic leukemia cells Blood 73 1989 753 762
-
(1989)
Blood
, vol.73
, pp. 753-762
-
-
Bregni, M.1
Siena, S.2
Formosa, A.3
Lappi, D.A.4
Martineau, D.5
Malavasi, F.6
Dorken, B.7
Bonadonna, G.8
Gianni, A.M.9
-
11
-
-
0030886711
-
Ricin fusion toxin targeted to the human granulocyte-macrophage colony-stimulating factor receptor is selectively toxic to acute myeloid leukemia cells
-
C. Burbage E.P. Tagge B. Harris P. Hall T. Fu M.C. Willingham A.E. Frankel Ricin fusion toxin targeted to the human granulocyte-macrophage colony-stimulating factor receptor is selectively toxic to acute myeloid leukemia cells Leuk. Res 21 1997 681 690
-
(1997)
Leuk. Res
, vol.21
, pp. 681-690
-
-
Burbage, C.1
Tagge, E.P.2
Harris, B.3
Hall, P.4
Fu, T.5
Willingham, M.C.6
Frankel, A.E.7
-
12
-
-
0031749971
-
Supersaturating infusional humanized anti-CD33 monoclonal antibody HuM195 in myelogenous leukemia
-
P.C. Caron L. Dumont D.A. Scheinberg Supersaturating infusional humanized anti-CD33 monoclonal antibody HuM195 in myelogenous leukemia Clin. Cancer Res 4 1998 1421 1428
-
(1998)
Clin. Cancer Res
, vol.4
, pp. 1421-1428
-
-
Caron, P.C.1
Dumont, L.2
Scheinberg, D.A.3
-
13
-
-
0029112836
-
A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells
-
C.H. Chan B.R. Blazar C.R. Eide R.J. Kreitman D.A. Vallera A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells Blood 86 1995 2732 2740
-
(1995)
Blood
, vol.86
, pp. 2732-2740
-
-
Chan, C.H.1
Blazar, B.R.2
Eide, C.R.3
Kreitman, R.J.4
Vallera, D.A.5
-
14
-
-
0025156656
-
Monoclonal anti-human T cell antibody and PAP-s conjugate: Preparation and selective cytotoxic properties on leukemic cell
-
J.Y. Chu A.D. Yang B.M. Wang Z. Hu X.M. Zhu H.J. Zhang J.H. Qu L.Y. Luo R. Guo L.R. Shi Monoclonal anti-human T cell antibody and PAP-s conjugate: Preparation and selective cytotoxic properties on leukemic cell J. Tongji Med. Univ 10 1990 15 18
-
(1990)
J. Tongji Med. Univ
, vol.10
, pp. 15-18
-
-
Chu, J.Y.1
Yang, A.D.2
Wang, B.M.3
Hu, Z.4
Zhu, X.M.5
Zhang, H.J.6
Qu, J.H.7
Luo, L.Y.8
Guo, R.9
Shi, L.R.10
-
16
-
-
0027175326
-
Exclusive production of bistranded DNA damage by calicheamicin
-
P.C. Dedon A.A. Salzberg J. Xu Exclusive production of bistranded DNA damage by calicheamicin Biochemistry 32 1993 3617 3622
-
(1993)
Biochemistry
, vol.32
, pp. 3617-3622
-
-
Dedon, P.C.1
Salzberg, A.A.2
Xu, J.3
-
17
-
-
0027428821
-
Toxin-targeted design for anticancer therapy. II. Preparation and biological comparison of different chemically linked gelonin-antibody conjugates
-
L. Delprino M. Giacomotti F. Dosio P. Brusa M. Ceruti G. Grosa L. Cattel Toxin-targeted design for anticancer therapy. II. Preparation and biological comparison of different chemically linked gelonin-antibody conjugates J. Pharm. Sci 82 1993 699 704
-
(1993)
J. Pharm. Sci
, vol.82
, pp. 699-704
-
-
Delprino, L.1
Giacomotti, M.2
Dosio, F.3
Brusa, P.4
Ceruti, M.5
Grosa, G.6
Cattel, L.7
-
18
-
-
0041995536
-
New advances in the treatment of acute promyelocytic leukemia
-
D. Douer New advances in the treatment of acute promyelocytic leukemia Int. J. Hematol 76 Suppl. 2 2002 179 187
-
(2002)
Int. J. Hematol
, vol.76
, Issue.Suppl. 2
, pp. 179-187
-
-
Douer, D.1
-
19
-
-
0025867193
-
The carbohydrate domain of calicheamicin gamma I1 determines its sequence specificity for DNA cleavage
-
J. Drak N. Iwasawa S. Danishefsky D.M. Crothers The carbohydrate domain of calicheamicin gamma I1 determines its sequence specificity for DNA cleavage Proc. Natl. Acad. Sci. USA 88 1991 7464 7468
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7464-7468
-
-
Drak, J.1
Iwasawa, N.2
Danishefsky, S.3
Crothers, D.M.4
-
20
-
-
0028929567
-
Identification of the ligand-binding domains of CD22, a member of the immunoglobulin superfamily that uniquely binds a sialic acid-dependent ligand
-
P. Engel N. Wagner A.S. Miller T.F. Tedder Identification of the ligand-binding domains of CD22, a member of the immunoglobulin superfamily that uniquely binds a sialic acid-dependent ligand J. Exp. Med 181 1995 1581 1586
-
(1995)
J. Exp. Med
, vol.181
, pp. 1581-1586
-
-
Engel, P.1
Wagner, N.2
Miller, A.S.3
Tedder, T.F.4
-
21
-
-
0025122427
-
Evaluation of ricin A chain-containing immunotoxins directed against the CD30 antigen as potential reagents for the treatment of Hodgkin's disease
-
A. Engert F. Burrows W. Jung P.L. Tazzari H. Stein M. Pfreundschuh V. Diehl P. Thorpe Evaluation of ricin A chain-containing immunotoxins directed against the CD30 antigen as potential reagents for the treatment of Hodgkin's disease Cancer Res 50 1990 84 88
-
(1990)
Cancer Res
, vol.50
, pp. 84-88
-
-
Engert, A.1
Burrows, F.2
Jung, W.3
Tazzari, P.L.4
Stein, H.5
Pfreundschuh, M.6
Diehl, V.7
Thorpe, P.8
-
22
-
-
0028866012
-
Cocktails of ricin A-chain immunotoxins against different antigens on Hodgkin and Sternberg-Reed cells have superior anti-tumor effects against H-RS cells in vitro and solid Hodgkin tumors in mice
-
A. Engert C. Gottstein H. Bohlen U. Winkler G. Schon O. Manske R. Schnell V. Diehl P. Thorpe Cocktails of ricin A-chain immunotoxins against different antigens on Hodgkin and Sternberg-Reed cells have superior anti-tumor effects against H-RS cells in vitro and solid Hodgkin tumors in mice Int. J. Cancer 63 1995 304 309
-
(1995)
Int. J. Cancer
, vol.63
, pp. 304-309
-
-
Engert, A.1
Gottstein, C.2
Bohlen, H.3
Winkler, U.4
Schon, G.5
Manske, O.6
Schnell, R.7
Diehl, V.8
Thorpe, P.9
-
23
-
-
0020444210
-
Properties of the ribosome-inactivating proteins gelonin, Momordica charantia inhibitor, and dianthins
-
A. Falasca A. Gasperi-Campani A. Abbondanza L. Barbieri F. Stirpe Properties of the ribosome-inactivating proteins gelonin, Momordica charantia inhibitor, and dianthins Biochem. J 207 1982 505 509
-
(1982)
Biochem. J
, vol.207
, pp. 505-509
-
-
Falasca, A.1
Gasperi-Campani, A.2
Abbondanza, A.3
Barbieri, L.4
Stirpe, F.5
-
24
-
-
0037328497
-
Treatment of relapsed or refractory acute myeloid leukemia with humanized anti-CD33 monoclonal antibody HuM195
-
E. Feldman M. Kalaycio G. Weiner S. Frankel P. Schulman L. Schwartzberg J. Jurcic E. Velez-Garcia K. Seiter D. Scheinberg D. Levitt N. Wedel Treatment of relapsed or refractory acute myeloid leukemia with humanized anti-CD33 monoclonal antibody HuM195 Leukemia 17 2003 314 318
-
(2003)
Leukemia
, vol.17
, pp. 314-318
-
-
Feldman, E.1
Kalaycio, M.2
Weiner, G.3
Frankel, S.4
Schulman, P.5
Schwartzberg, L.6
Jurcic, J.7
Velez-Garcia, E.8
Seiter, K.9
Scheinberg, D.10
Levitt, D.11
Wedel, N.12
-
25
-
-
0034537062
-
Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells
-
M. Feuring-Buske A. Frankel B. Gerhard D. Hogge Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells Exp. Hematol 28 2000 1390 1400
-
(2000)
Exp. Hematol
, vol.28
, pp. 1390-1400
-
-
Feuring-Buske, M.1
Frankel, A.2
Gerhard, B.3
Hogge, D.4
-
26
-
-
0035103315
-
Therapy of human T-cell acute lymphoblastic leukaemia with a combination of anti-CD7 and anti-CD38-SAPORIN immunotoxins is significantly better than therapy with each individual immunotoxin
-
D.J. Flavell D.A. Boehm A. Noss S.L. Warnes S.U. Flavell Therapy of human T-cell acute lymphoblastic leukaemia with a combination of anti-CD7 and anti-CD38-SAPORIN immunotoxins is significantly better than therapy with each individual immunotoxin Br. J. Cancer 84 2001 571 578
-
(2001)
Br. J. Cancer
, vol.84
, pp. 571-578
-
-
Flavell, D.J.1
Boehm, D.A.2
Noss, A.3
Warnes, S.L.4
Flavell, S.U.5
-
27
-
-
0036098391
-
Phase I trial of a novel diptheria toxin⧸granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia
-
A.E. Frankel B.L. Powell P.D. Hall L.D. Cawe R.J. Kreitman Phase I trial of a novel diptheria toxin⧸granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia Clin. Cancer Res 8 2002 1004 1013
-
(2002)
Clin. Cancer Res
, vol.8
, pp. 1004-1013
-
-
Frankel, A.E.1
Powell, B.L.2
Hall, P.D.3
Cawe, L.D.4
Kreitman, R.J.5
-
30
-
-
0030784767
-
Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein
-
A.E. Frankel P.D. Hall C. Burbage J. Vesely M. Willingham K. Bhalla R.J. Kreitman Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein Blood 90 1997 3654 3661
-
(1997)
Blood
, vol.90
, pp. 3654-3661
-
-
Frankel, A.E.1
Hall, P.D.2
Burbage, C.3
Vesely, J.4
Willingham, M.5
Bhalla, K.6
Kreitman, R.J.7
-
31
-
-
0029012629
-
Delivery of the ribosome-inactivating protein, gelonin, to lymphoma cells via CD22 and CD38 using bispecific antibodies
-
R.R. French C.A. Penney A.C. Browning F. Stirpe A.J. George M.J. Glennie Delivery of the ribosome-inactivating protein, gelonin, to lymphoma cells via CD22 and CD38 using bispecific antibodies Br. J. Cancer 71 1995 986 994
-
(1995)
Br. J. Cancer
, vol.71
, pp. 986-994
-
-
French, R.R.1
Penney, C.A.2
Browning, A.C.3
Stirpe, F.4
George, A.J.5
Glennie, M.J.6
-
32
-
-
0023886893
-
Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy
-
M.A. Ghetie R.D. May M. Till J.W. Uhr V. Ghetie P.P. Knowles M. Relf A. Brown P.M. Wallace G. Janossy Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy Cancer Res 48 1988 2610 2617
-
(1988)
Cancer Res
, vol.48
, pp. 2610-2617
-
-
Ghetie, M.A.1
May, R.D.2
Till, M.3
Uhr, J.W.4
Ghetie, V.5
Knowles, P.P.6
Relf, M.7
Brown, A.8
Wallace, P.M.9
Janossy, G.10
-
33
-
-
0026803031
-
The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin
-
M.A. Ghetie K. Tucker J. Richardson J.W. Uhr E.S. Vitetta The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin Blood 80 1992 2315 2320
-
(1992)
Blood
, vol.80
, pp. 2315-2320
-
-
Ghetie, M.A.1
Tucker, K.2
Richardson, J.3
Uhr, J.W.4
Vitetta, E.S.5
-
34
-
-
3042612638
-
Transferrin toxin but not transferrin receptor immunotoxin is influenced by free transferrin and iron saturation
-
P.H. Gosselaar A.J. van Dijk G.C. de Gast L. Polito A. Bolognesi W.C. Vooijs A.F. Verheul H.G. Krouwer J.J. Marx Transferrin toxin but not transferrin receptor immunotoxin is influenced by free transferrin and iron saturation Eur. J. Clin. Invest 32 Suppl. 1 2002 61 69
-
(2002)
Eur. J. Clin. Invest
, vol.32
, Issue.Suppl. 1
, pp. 61-69
-
-
Gosselaar, P.H.1
van Dijk, A.J.2
de Gast, G.C.3
Polito, L.4
Bolognesi, A.5
Vooijs, W.C.6
Verheul, A.F.7
Krouwer, H.G.8
Marx, J.J.9
-
35
-
-
0021222051
-
A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cells
-
J.D. Griffin D. Linch K. Sabbath P. Larcom S.F. Schlossman A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cells Leuk. Res 8 1984 521 534
-
(1984)
Leuk. Res
, vol.8
, pp. 521-534
-
-
Griffin, J.D.1
Linch, D.2
Sabbath, K.3
Larcom, P.4
Schlossman, S.F.5
-
36
-
-
0027394952
-
In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia⧸lymphoma in mice with severe combined immunodeficiency
-
R. Gunther L.M. Chelstrom D. Finnegan L. Tuel-Ahlgren J.D. Irvin D.E. Myers F.M. Uckun In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia⧸lymphoma in mice with severe combined immunodeficiency Leukemia 7 1993 298 309
-
(1993)
Leukemia
, vol.7
, pp. 298-309
-
-
Gunther, R.1
Chelstrom, L.M.2
Finnegan, D.3
Tuel-Ahlgren, L.4
Irvin, J.D.5
Myers, D.E.6
Uckun, F.M.7
-
37
-
-
0031595964
-
Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL⧸6 mice
-
P.D. Hall R.J. Kreitman M.C. Willingham A.E. Frankel Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL⧸6 mice Toxicol. Appl. Pharmacol 150 1998 91 97
-
(1998)
Toxicol. Appl. Pharmacol
, vol.150
, pp. 91-97
-
-
Hall, P.D.1
Kreitman, R.J.2
Willingham, M.C.3
Frankel, A.E.4
-
38
-
-
0242516121
-
The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity
-
P.D. Hall B.I. Razzouk T.E. Willoughby T.W. McLean A.E. Frankel The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity J. Pediatr. Hematol. Oncol 24 2002 521 526
-
(2002)
J. Pediatr. Hematol. Oncol
, vol.24
, pp. 521-526
-
-
Hall, P.D.1
Razzouk, B.I.2
Willoughby, T.E.3
McLean, T.W.4
Frankel, A.E.5
-
39
-
-
0034895032
-
Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony-stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia
-
P.D. Hall G. Virella T. Willoughby D.H. Atchley R.J. Kreitman A.E. Frankel Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony-stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia Clin. Immunol 100 2001 191 197
-
(2001)
Clin. Immunol
, vol.100
, pp. 191-197
-
-
Hall, P.D.1
Virella, G.2
Willoughby, T.3
Atchley, D.H.4
Kreitman, R.J.5
Frankel, A.E.6
-
40
-
-
0025907541
-
In vitro studies of the effect of MAb NDA 4 linked to toxin on the proliferation of a human EBV-transformed lymphoblastoid B cell line and of gibbon MLA leukemia cell line
-
P. Harris E. Reed D.W. King N. Suciu-Foca In vitro studies of the effect of MAb NDA 4 linked to toxin on the proliferation of a human EBV-transformed lymphoblastoid B cell line and of gibbon MLA leukemia cell line Cell Immunol 134 1991 85 95
-
(1991)
Cell Immunol
, vol.134
, pp. 85-95
-
-
Harris, P.1
Reed, E.2
King, D.W.3
Suciu-Foca, N.4
-
41
-
-
20244379085
-
Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein
-
D.E. Hogge C.L. Willman R.J. Kreitman M. Berger P.D. Hall K.J. Kopecky C. McLain E.P. Tagge C.J. Eaves A.E. Frankel Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein Blood 92 1998 589 595
-
(1998)
Blood
, vol.92
, pp. 589-595
-
-
Hogge, D.E.1
Willman, C.L.2
Kreitman, R.J.3
Berger, M.4
Hall, P.D.5
Kopecky, K.J.6
McLain, C.7
Tagge, E.P.8
Eaves, C.J.9
Frankel, A.E.10
-
42
-
-
0027787966
-
Cytotoxicity of a novel anti-ICAM-1 immunotoxin on human myeloma cell lines
-
Y.W. Huang F.J. Burrows E.S. Vitetta Cytotoxicity of a novel anti-ICAM-1 immunotoxin on human myeloma cell lines Hybridoma 12 1993 661 675
-
(1993)
Hybridoma
, vol.12
, pp. 661-675
-
-
Huang, Y.W.1
Burrows, F.J.2
Vitetta, E.S.3
-
43
-
-
0035893923
-
Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma
-
M. Huhn S. Sasse M.K. Tur B. Matthey T. Schinkothe S.M. Rybak S. Barth A. Engert Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma Cancer Res 61 2001 8737 8742
-
(2001)
Cancer Res
, vol.61
, pp. 8737-8742
-
-
Huhn, M.1
Sasse, S.2
Tur, M.K.3
Matthey, B.4
Schinkothe, T.5
Rybak, S.M.6
Barth, S.7
Engert, A.8
-
44
-
-
0036237495
-
Specifically targeting the CD22 receptor of human B-cell lymphomas with RNA damaging agents: a new generation of therapeutics
-
M. Hursey D.L. Newton H. Hansen D. Ruby D.M. Goldenberg S.M. Rybak Specifically targeting the CD22 receptor of human B-cell lymphomas with RNA damaging agents: a new generation of therapeutics Leuk. Lymph 43 2002 953 959
-
(2002)
Leuk. Lymph
, vol.43
, pp. 953-959
-
-
Hursey, M.1
Newton, D.L.2
Hansen, H.3
Ruby, D.4
Goldenberg, D.M.5
Rybak, S.M.6
-
45
-
-
0032982762
-
Interleukin-4 receptor-directed cytotoxin therapy of AIDS-associated Kaposi's sarcoma tumors in xenograft model
-
S.R. Husain R.J. Kreitman I. Pastan R.K. Puri Interleukin-4 receptor-directed cytotoxin therapy of AIDS-associated Kaposi's sarcoma tumors in xenograft model Nat. Med 5 1999 817 822
-
(1999)
Nat. Med
, vol.5
, pp. 817-822
-
-
Husain, S.R.1
Kreitman, R.J.2
Pastan, I.3
Puri, R.K.4
-
46
-
-
0026534439
-
Characterization of the defect in a variant of HL-60 promyelocytic leukemia cells with reduced transferrin receptor expression
-
K. Ishiguro P.T. Ho A.C. Sartorelli Characterization of the defect in a variant of HL-60 promyelocytic leukemia cells with reduced transferrin receptor expression Somat. Cell Mol. Genet 18 1992 45 63
-
(1992)
Somat. Cell Mol. Genet
, vol.18
, pp. 45-63
-
-
Ishiguro, K.1
Ho, P.T.2
Sartorelli, A.C.3
-
47
-
-
0037148426
-
IL-4 receptors on human medulloblastoma tumours serve as a sensitive target for a circular permuted IL-4-Pseudomonas exotoxin fusion protein
-
B.H. Joshi P. Leland J. Silber R.J. Kreitman I. Pastan M. Berger R.K. Puri IL-4 receptors on human medulloblastoma tumours serve as a sensitive target for a circular permuted IL-4- Pseudomonas exotoxin fusion protein Br. J. Cancer 86 2002 285 291
-
(2002)
Br. J. Cancer
, vol.86
, pp. 285-291
-
-
Joshi, B.H.1
Leland, P.2
Silber, J.3
Kreitman, R.J.4
Pastan, I.5
Berger, M.6
Puri, R.K.7
-
48
-
-
0033982749
-
Molecular remission induction with retinoic acid and anti-CD33 monoclonal antibody HuM195 in acute promyelocytic leukemia
-
J.G. Jurcic T. DeBlasio L. Dumont T.J. Yao D.A. Scheinberg Molecular remission induction with retinoic acid and anti-CD33 monoclonal antibody HuM195 in acute promyelocytic leukemia Clin. Cancer Res 6 2000 372 380
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 372-380
-
-
Jurcic, J.G.1
DeBlasio, T.2
Dumont, L.3
Yao, T.J.4
Scheinberg, D.A.5
-
49
-
-
0024311962
-
Cytotoxicity of interleukin 2-toxin toward lymphocytes from patients with adult T-cell leukemia
-
T. Kiyokawa K. Shirono T. Hattori H. Nishimura K. Yamaguchi J.C. Nichols T.B. Strom J.R. Murphy K. Takatsuki Cytotoxicity of interleukin 2-toxin toward lymphocytes from patients with adult T-cell leukemia Cancer Res 49 1989 4042 4046
-
(1989)
Cancer Res
, vol.49
, pp. 4042-4046
-
-
Kiyokawa, T.1
Shirono, K.2
Hattori, T.3
Nishimura, H.4
Yamaguchi, K.5
Nichols, J.C.6
Strom, T.B.7
Murphy, J.R.8
Takatsuki, K.9
-
50
-
-
0035214047
-
Toxin-labeled monoclonal antibodies
-
R.J. Kreitman Toxin-labeled monoclonal antibodies Curr. Pharm. Biotechnol 2 2001 313 325
-
(2001)
Curr. Pharm. Biotechnol
, vol.2
, pp. 313-325
-
-
Kreitman, R.J.1
-
51
-
-
0037299714
-
Recombinant toxins for the treatment of cancer
-
R.J. Kreitman Recombinant toxins for the treatment of cancer Curr. Opin. Mol. Ther 5 2003 44 51
-
(2003)
Curr. Opin. Mol. Ther
, vol.5
, pp. 44-51
-
-
Kreitman, R.J.1
-
52
-
-
0034048735
-
Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) toward fresh malignant cells from patients with B-cell leukemias
-
R.J. Kreitman I. Margulies M. Stetler-Stevenson Q.C. Wang D.J. FitzGerald I. Pastan Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) toward fresh malignant cells from patients with B-cell leukemias Clin. Cancer Res 6 2000 1476 1487
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 1476-1487
-
-
Kreitman, R.J.1
Margulies, I.2
Stetler-Stevenson, M.3
Wang, Q.C.4
FitzGerald, D.J.5
Pastan, I.6
-
54
-
-
0033047767
-
Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys
-
R.J. Kreitman Q.C. Wang D.J. FitzGerald I. Pastan Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys Int. J. Cancer 81 1999 148 155
-
(1999)
Int. J. Cancer
, vol.81
, pp. 148-155
-
-
Kreitman, R.J.1
Wang, Q.C.2
FitzGerald, D.J.3
Pastan, I.4
-
56
-
-
0025740260
-
Monoclonal antibodies in myeloid diseases: Prognostic use in acute myeloid leukaemia
-
J.S. Kristensen P. Hokland Monoclonal antibodies in myeloid diseases: Prognostic use in acute myeloid leukaemia Leuk. Res 15 1991 693 700
-
(1991)
Leuk. Res
, vol.15
, pp. 693-700
-
-
Kristensen, J.S.1
Hokland, P.2
-
57
-
-
0027292385
-
Phase I trial of a 90-minute infusion of the fusion toxin DAB486IL-2 in hematological cancers
-
C.F. LeMaistre F.E. Craig C. Meneghetti B. McMullin K. Parker J. Reuben D.H. Boldt M. Rosenblum T. Woodworth Phase I trial of a 90-minute infusion of the fusion toxin DAB486IL-2 in hematological cancers Cancer Res 53 1993 3930 3934
-
(1993)
Cancer Res
, vol.53
, pp. 3930-3934
-
-
LeMaistre, C.F.1
Craig, F.E.2
Meneghetti, C.3
McMullin, B.4
Parker, K.5
Reuben, J.6
Boldt, D.H.7
Rosenblum, M.8
Woodworth, T.9
-
58
-
-
0030819578
-
An in vitro model for toxin-mediated vascular leak syndrome: Ricin toxin A chain increases the permeability of human endothelial cell monolayers
-
A.L. Lindstrom S.L. Erlandsen J.H. Kersey C.A. Pennell An in vitro model for toxin-mediated vascular leak syndrome: Ricin toxin A chain increases the permeability of human endothelial cell monolayers Blood 90 1997 2323 2334
-
(1997)
Blood
, vol.90
, pp. 2323-2334
-
-
Lindstrom, A.L.1
Erlandsen, S.L.2
Kersey, J.H.3
Pennell, C.A.4
-
59
-
-
0026165475
-
Immunophenotypic characterisation of monocytoid differentiation markers in acute non-lymphoblastic leukaemias
-
T.C. Liu G.B. Tan C.L. Wong P. Han Immunophenotypic characterisation of monocytoid differentiation markers in acute non-lymphoblastic leukaemias Ann. Acad. Med. Singapore 20 1991 353 355
-
(1991)
Ann. Acad. Med. Singapore
, vol.20
, pp. 353-355
-
-
Liu, T.C.1
Tan, G.B.2
Wong, C.L.3
Han, P.4
-
60
-
-
0029057002
-
Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors
-
I.A. Lorimer C.J. Wikstrand S.K. Batra D.D. Bigner I. Pastan Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors Clin. Cancer Res 1 1995 859 864
-
(1995)
Clin. Cancer Res
, vol.1
, pp. 859-864
-
-
Lorimer, I.A.1
Wikstrand, C.J.2
Batra, S.K.3
Bigner, D.D.4
Pastan, I.5
-
61
-
-
0030954684
-
Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors
-
E. Mansfield P. Amlot I. Pastan D.J. FitzGerald Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors Blood 90 1997 2020 2026
-
(1997)
Blood
, vol.90
, pp. 2020-2026
-
-
Mansfield, E.1
Amlot, P.2
Pastan, I.3
FitzGerald, D.J.4
-
63
-
-
0030250422
-
Characterization of RFB4-Pseudomonas exotoxin A immunotoxins targeted to CD22 on B-cell malignancies
-
E. Mansfield I. Pastan D.J. FitzGerald Characterization of RFB4- Pseudomonas exotoxin A immunotoxins targeted to CD22 on B-cell malignancies Bioconj. Chem 7 1996 557 563
-
(1996)
Bioconj. Chem
, vol.7
, pp. 557-563
-
-
Mansfield, E.1
Pastan, I.2
FitzGerald, D.J.3
-
64
-
-
0027502636
-
Cytotoxic activity of lutropin-gelonin conjugate in mouse Leydig tumor cells: Potentiation of the hormonotoxin activity by different drugs
-
J. Marcil N. Ravindranath M.R. Sairam Cytotoxic activity of lutropin-gelonin conjugate in mouse Leydig tumor cells: Potentiation of the hormonotoxin activity by different drugs Mol. Cell Endocrinol 92 1993 83 90
-
(1993)
Mol. Cell Endocrinol
, vol.92
, pp. 83-90
-
-
Marcil, J.1
Ravindranath, N.2
Sairam, M.R.3
-
66
-
-
0022870818
-
Selective killing of normal and neoplastic human B cells with anti-CD19- and anti-CD22-ricin A chain immunotoxins
-
R.D. May E.S. Vitetta G. Moldenhauer B. Dorken Selective killing of normal and neoplastic human B cells with anti-CD19- and anti-CD22-ricin A chain immunotoxins Cancer Drug Deliv 3 1986 261 272
-
(1986)
Cancer Drug Deliv
, vol.3
, pp. 261-272
-
-
May, R.D.1
Vitetta, E.S.2
Moldenhauer, G.3
Dorken, B.4
-
68
-
-
0028109444
-
Characterization of murine and humanized anti-CD33, gelonin immunotoxins reactive against myeloid leukemias
-
K.J. McGraw M.G. Rosenblum L. Cheung D.A. Scheinberg Characterization of murine and humanized anti-CD33, gelonin immunotoxins reactive against myeloid leukemias Cancer Immunol. Immunother 39 1994 367 374
-
(1994)
Cancer Immunol. Immunother
, vol.39
, pp. 367-374
-
-
McGraw, K.J.1
Rosenblum, M.G.2
Cheung, L.3
Scheinberg, D.A.4
-
69
-
-
4444351637
-
Retinoic acid-induced CD38 antigen as a target for immunotoxin-mediated killing of leukemia cells
-
K. Mehta L. Ocanas F. Malavasi J.W. Marks M.G. Rosenblum Retinoic acid-induced CD38 antigen as a target for immunotoxin-mediated killing of leukemia cells Mol. Cancer Ther 3 2004 345 352
-
(2004)
Mol. Cancer Ther
, vol.3
, pp. 345-352
-
-
Mehta, K.1
Ocanas, L.2
Malavasi, F.3
Marks, J.W.4
Rosenblum, M.G.5
-
70
-
-
0030223054
-
Treatment of human B-cell precursor leukemia in SCID mice using a combination of the investigational biotherapeutic agent B43-PAP with cytosine arabinoside
-
Y. Messinger Y. Yanishevski V.I. Avramis O. Ek L.M. Chelstrom R. Gunther D.E. Myers J.D. Irvin W. Evans F.M. Uckun Treatment of human B-cell precursor leukemia in SCID mice using a combination of the investigational biotherapeutic agent B43-PAP with cytosine arabinoside Clin. Cancer Res 2 1996 1533 1542
-
(1996)
Clin. Cancer Res
, vol.2
, pp. 1533-1542
-
-
Messinger, Y.1
Yanishevski, Y.2
Avramis, V.I.3
Ek, O.4
Chelstrom, L.M.5
Gunther, R.6
Myers, D.E.7
Irvin, J.D.8
Evans, W.9
Uckun, F.M.10
-
71
-
-
0029146641
-
An anti-CD72 immunotoxin against therapy-refractory B-lineage acute lymphoblastic leukemia
-
D.E. Myers F.M. Uckun An anti-CD72 immunotoxin against therapy-refractory B-lineage acute lymphoblastic leukemia Leuk. Lymphoma 18 1995 119 122
-
(1995)
Leuk. Lymphoma
, vol.18
, pp. 119-122
-
-
Myers, D.E.1
Uckun, F.M.2
-
72
-
-
0036226759
-
Early phase I⧸II trials with gemtuzumab ozogamicin (Mylotarg®) in acute myeloid leukemia
-
C. Nabhan M.S. Tallman Early phase I⧸II trials with gemtuzumab ozogamicin (Mylotarg®) in acute myeloid leukemia Clin. Lymph 2 Suppl. 1 2002 S19 S23
-
(2002)
Clin. Lymph
, vol.2
, Issue.Suppl. 1
, pp. S19-S23
-
-
Nabhan, C.1
Tallman, M.S.2
-
73
-
-
0030888194
-
Interleukin-2 fusion protein: An investigational therapy for interleukin-2 receptor expressing malignancies
-
J. Nichols F. Foss T.M. Kuzel C.F. LeMaistre L. Platanias M.J. Ratain A. Rook M. Saleh G. Schwartz Interleukin-2 fusion protein: An investigational therapy for interleukin-2 receptor expressing malignancies Eur. J. Cancer 33 Suppl. 1 1997 S34 S36
-
(1997)
Eur. J. Cancer
, vol.33
, Issue.Suppl. 1
, pp. S34-S36
-
-
Nichols, J.1
Foss, F.2
Kuzel, T.M.3
LeMaistre, C.F.4
Platanias, L.5
Ratain, M.J.6
Rook, A.7
Saleh, M.8
Schwartz, G.9
-
74
-
-
0025119680
-
Cytotoxicity of a recombinant ricin-A-chain fusion protein containing a proteolytically-cleavable spacer sequence
-
M. O'Hare A.N. Brown K. Hussain A. Gebhardt G. Watson L.M. Roberts E.S. Vitetta P.E. Thorpe J.M. Lord Cytotoxicity of a recombinant ricin-A-chain fusion protein containing a proteolytically-cleavable spacer sequence FEBS Lett 273 1990 200 204
-
(1990)
FEBS Lett
, vol.273
, pp. 200-204
-
-
O'Hare, M.1
Brown, A.N.2
Hussain, K.3
Gebhardt, A.4
Watson, G.5
Roberts, L.M.6
Vitetta, E.S.7
Thorpe, P.E.8
Lord, J.M.9
-
75
-
-
0024154373
-
Adriamycin custom-tailored immunoconjugates in the treatment of human malignancies
-
R.K. Oldham M. Lewis D.W. Orr B. Avner S.K. Liao J.R. Ogden B. Avner R. Birch Adriamycin custom-tailored immunoconjugates in the treatment of human malignancies Mol. Biother 1 1988 103 113
-
(1988)
Mol. Biother
, vol.1
, pp. 103-113
-
-
Oldham, R.K.1
Lewis, M.2
Orr, D.W.3
Avner, B.4
Liao, S.K.5
Ogden, J.R.6
Avner, B.7
Birch, R.8
-
77
-
-
0038290547
-
Immunotoxins containing Pseudomonas exotoxin A: A short history
-
I. Pastan Immunotoxins containing Pseudomonas exotoxin A: A short history Cancer Immunol. Immunother 52 2003 338 341
-
(2003)
Cancer Immunol. Immunother
, vol.52
, pp. 338-341
-
-
Pastan, I.1
-
78
-
-
0033939774
-
Targeting activated lymphocytes with an entirely human immunotoxin analogue: Human pancreatic RNase1-human IL-2 fusion
-
K. Psarras M. Ueda M. Tanabe M. Kitajima S. Aiso S. Komatsu M. Seno Targeting activated lymphocytes with an entirely human immunotoxin analogue: Human pancreatic RNase1-human IL-2 fusion Cytokine 12 2000 786 790
-
(2000)
Cytokine
, vol.12
, pp. 786-790
-
-
Psarras, K.1
Ueda, M.2
Tanabe, M.3
Kitajima, M.4
Aiso, S.5
Komatsu, S.6
Seno, M.7
-
79
-
-
0026686354
-
Human bone marrow depleted of CD33-positive cells mediates delayed but durable reconstitution of hematopoiesis: Clinical trial of MY9 monoclonal antibody-purged autografts for the treatment of acute myeloid leukemia
-
M.J. Robertson R.J. Soiffer A.S. Freedman S.L. Rabinowe K.C. Anderson T.J. Ervin C. Murray K. Dear J.D. Griffin L.M. Nadler Human bone marrow depleted of CD33-positive cells mediates delayed but durable reconstitution of hematopoiesis: Clinical trial of MY9 monoclonal antibody-purged autografts for the treatment of acute myeloid leukemia Blood 79 1992 2229 2236
-
(1992)
Blood
, vol.79
, pp. 2229-2236
-
-
Robertson, M.J.1
Soiffer, R.J.2
Freedman, A.S.3
Rabinowe, S.L.4
Anderson, K.C.5
Ervin, T.J.6
Murray, C.7
Dear, K.8
Griffin, J.D.9
Nadler, L.M.10
-
80
-
-
0036784822
-
Efficacy and safety of gemtuzumab ozogamicin in patients with poor-prognosis acute myeloid leukemia
-
G.J. Roboz M.A. Knovich R.L. Bayer M.W. Schuster K. Seiter B.L. Powell R.D. Woodruff R.T. Silver A.E. Frankel E.J. Feldman Efficacy and safety of gemtuzumab ozogamicin in patients with poor-prognosis acute myeloid leukemia Leuk. Lymph 43 2002 1951 1955
-
(2002)
Leuk. Lymph
, vol.43
, pp. 1951-1955
-
-
Roboz, G.J.1
Knovich, M.A.2
Bayer, R.L.3
Schuster, M.W.4
Seiter, K.5
Powell, B.L.6
Woodruff, R.D.7
Silver, R.T.8
Frankel, A.E.9
Feldman, E.J.10
-
82
-
-
0029057959
-
Amino acid sequence analysis, gene construction, cloning, and expression of gelonin, a toxin derived from Gelonium multiflorum
-
M.G. Rosenblum W.A. Kohr K.L. Beattie W.G. Beattie W. Marks P.D. Toman L. Cheung Amino acid sequence analysis, gene construction, cloning, and expression of gelonin, a toxin derived from Gelonium multiflorum J. Interferon Cytokine Res 15 1995 547 555
-
(1995)
J. Interferon Cytokine Res
, vol.15
, pp. 547-555
-
-
Rosenblum, M.G.1
Kohr, W.A.2
Beattie, K.L.3
Beattie, W.G.4
Marks, W.5
Toman, P.D.6
Cheung, L.7
-
83
-
-
0032808621
-
Comparative cytotoxicity and pharmacokinetics of antimelanoma immunotoxins containing either natural or recombinant gelonin
-
M.G. Rosenblum J.W. Marks L.H. Cheung Comparative cytotoxicity and pharmacokinetics of antimelanoma immunotoxins containing either natural or recombinant gelonin Cancer Chemother. Pharmacol 44 1999 343 348
-
(1999)
Cancer Chemother. Pharmacol
, vol.44
, pp. 343-348
-
-
Rosenblum, M.G.1
Marks, J.W.2
Cheung, L.H.3
-
84
-
-
0035877041
-
Isolation of new anti-CD30 scFvs from DNA-immunized mice by phage display and biologic activity of recombinant immunotoxins produced by fusion with truncated Pseudomonas exotoxin
-
H. Rozemuller P.S. Chowdhury I. Pastan R.J. Kreitman Isolation of new anti-CD30 scFvs from DNA-immunized mice by phage display and biologic activity of recombinant immunotoxins produced by fusion with truncated Pseudomonas exotoxin Int. J. Cancer 92 2001 861 870
-
(2001)
Int. J. Cancer
, vol.92
, pp. 861-870
-
-
Rozemuller, H.1
Chowdhury, P.S.2
Pastan, I.3
Kreitman, R.J.4
-
85
-
-
0029056665
-
Continuous infusion of the anti-CD22 immunotoxin IgG-RFB4-SMPT-dgA in patients with B-cell lymphoma: A phase I study
-
E.A. Sausville D. Headlee M. Stetler-Stevenson E.S. Jaffe D. Solomon W.D. Figg J. Herdt W.C. Kopp H. Rager S.M. Steinberg Continuous infusion of the anti-CD22 immunotoxin IgG-RFB4-SMPT-dgA in patients with B-cell lymphoma: A phase I study Blood 85 1995 3457 3465
-
(1995)
Blood
, vol.85
, pp. 3457-3465
-
-
Sausville, E.A.1
Headlee, D.2
Stetler-Stevenson, M.3
Jaffe, E.S.4
Solomon, D.5
Figg, W.D.6
Herdt, J.7
Kopp, W.C.8
Rager, H.9
Steinberg, S.M.10
-
87
-
-
0024207837
-
Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas
-
G.L. Shen J.L. Li M.A. Ghetie V. Ghetie R.D. May M. Till A.N. Brown M. Relf P. Knowles J.W. Uhr Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas Int. J. Cancer 42 1988 792 797
-
(1988)
Int. J. Cancer
, vol.42
, pp. 792-797
-
-
Shen, G.L.1
Li, J.L.2
Ghetie, M.A.3
Ghetie, V.4
May, R.D.5
Till, M.6
Brown, A.N.7
Relf, M.8
Knowles, P.9
Uhr, J.W.10
-
88
-
-
0043160581
-
Targeted cytotoxic effect of anti-JL1 immunotoxin against a human leukemic cell line and its clinical implications
-
Y.K. Shin Y.L. Choi E.Y. Choi M.K. Kim M.C. Kook J. Chung Y.K. Choi H.S. Kim H.G. Song S.H. Park Targeted cytotoxic effect of anti-JL1 immunotoxin against a human leukemic cell line and its clinical implications Cancer Immunol. Immunother 52 2003 506 512
-
(2003)
Cancer Immunol. Immunother
, vol.52
, pp. 506-512
-
-
Shin, Y.K.1
Choi, Y.L.2
Choi, E.Y.3
Kim, M.K.4
Kook, M.C.5
Chung, J.6
Choi, Y.K.7
Kim, H.S.8
Song, H.G.9
Park, S.H.10
-
89
-
-
0036354718
-
Expression of HER2 in human gastric cancer cells directly correlates with antitumor activity of a recombinant disulfide-stabilized anti-HER2 immunotoxin
-
H. Shinohara S. Morita M. Kawai A. Miyamoto T. Sonoda I. Pastan N. Tanigawa Expression of HER2 in human gastric cancer cells directly correlates with antitumor activity of a recombinant disulfide-stabilized anti-HER2 immunotoxin J. Surg. Res 102 2002 169 177
-
(2002)
J. Surg. Res
, vol.102
, pp. 169-177
-
-
Shinohara, H.1
Morita, S.2
Kawai, M.3
Miyamoto, A.4
Sonoda, T.5
Pastan, I.6
Tanigawa, N.7
-
90
-
-
0024322152
-
Immunotoxin-mediated inhibition of chronic lymphocytic leukemia cell proliferation in humans
-
S. Siena M. Bregni A. Formosa B. Brando P. Marenco D.A. Lappi G. Bonadonna A.M. Gianni Immunotoxin-mediated inhibition of chronic lymphocytic leukemia cell proliferation in humans Cancer Res 49 1989 3328 3332
-
(1989)
Cancer Res
, vol.49
, pp. 3328-3332
-
-
Siena, S.1
Bregni, M.2
Formosa, A.3
Brando, B.4
Marenco, P.5
Lappi, D.A.6
Bonadonna, G.7
Gianni, A.M.8
-
91
-
-
0023691747
-
Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells
-
D. Simmons B. Seed Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells J. Immunol 141 1988 2797 2800
-
(1988)
J. Immunol
, vol.141
, pp. 2797-2800
-
-
Simmons, D.1
Seed, B.2
-
92
-
-
0036718673
-
Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia
-
E.A. Stadtmauer Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia Curr. Oncol. Rep 4 2002 375 380
-
(2002)
Curr. Oncol. Rep
, vol.4
, pp. 375-380
-
-
Stadtmauer, E.A.1
-
93
-
-
0019212385
-
Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
-
F. Stirpe S. Olsnes A. Pihl Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A J. Biol. Chem 255 1980 6947 6953
-
(1980)
J. Biol. Chem
, vol.255
, pp. 6947-6953
-
-
Stirpe, F.1
Olsnes, S.2
Pihl, A.3
-
94
-
-
0027461913
-
Interleukin-2 receptor-directed therapies: Antibody- or cytokine-based targeting molecules
-
T.B. Strom V.R. Kelley J.R. Murphy J. Nichols T.G. Woodworth Interleukin-2 receptor-directed therapies: Antibody- or cytokine-based targeting molecules Annu. Rev. Med 44 1993 343 353
-
(1993)
Annu. Rev. Med
, vol.44
, pp. 343-353
-
-
Strom, T.B.1
Kelley, V.R.2
Murphy, J.R.3
Nichols, J.4
Woodworth, T.G.5
-
95
-
-
0032031693
-
Interleukin 7 (IL-7) receptor-specific cell killing by DAB389 IL-7: A novel agent for the elimination of IL-7 receptor positive cells
-
E.B. Sweeney F.M. Foss J.R. Murphy J.C. vanderSpek Interleukin 7 (IL-7) receptor-specific cell killing by DAB389 IL-7: A novel agent for the elimination of IL-7 receptor positive cells Bioconj. Chem 9 1998 201 207
-
(1998)
Bioconj. Chem
, vol.9
, pp. 201-207
-
-
Sweeney, E.B.1
Foss, F.M.2
Murphy, J.R.3
vanderSpek, J.C.4
-
96
-
-
85120204271
-
-
M. Talpaz K. Hagop E. Freireich V. Lopez W. Zhang J. Cortes-Franco D. Scheinberg M.G. Rosenblum Phase I clinical trial of the anti-CD-33 immunotoxin HuM195⧸rGel Proceedings of the AACR. Cadmus Professional Communications, Linthicum, MD, Abstract # 5362, 44, 1228. 2003
-
(2003)
-
-
Talpaz, M.1
Hagop, K.2
Freireich, E.3
Lopez, V.4
Zhang, W.5
Cortes-Franco, J.6
Scheinberg, D.7
Rosenblum, M.G.8
-
97
-
-
0024509637
-
Restricted expression of an early myeloid and monocytic cell surface antigen defined by monoclonal antibody M195
-
M. Tanimoto D.A. Scheinberg C. Cordon-Cardo D. Huie B.D. Clarkson L.J. Old Restricted expression of an early myeloid and monocytic cell surface antigen defined by monoclonal antibody M195 Leukemia 3 1989 339 348
-
(1989)
Leukemia
, vol.3
, pp. 339-348
-
-
Tanimoto, M.1
Scheinberg, D.A.2
Cordon-Cardo, C.3
Huie, D.4
Clarkson, B.D.5
Old, L.J.6
-
98
-
-
0027216217
-
Targeting of saporin to CD25-positive normal and neoplastic lymphocytes by an anti-saporin⧸anti-CD25 bispecific monoclonal antibody: In vitro evaluation
-
P.L. Tazzari S. Zhang Q. Chen S. Sforzini A. Bolognesi F. Stirpe H. Xie A. Moretta S. Ferrini Targeting of saporin to CD25-positive normal and neoplastic lymphocytes by an anti-saporin⧸anti-CD25 bispecific monoclonal antibody: In vitro evaluation Br. J. Cancer 67 1993 1248 1253
-
(1993)
Br. J. Cancer
, vol.67
, pp. 1248-1253
-
-
Tazzari, P.L.1
Zhang, S.2
Chen, Q.3
Sforzini, S.4
Bolognesi, A.5
Stirpe, F.6
Xie, H.7
Moretta, A.8
Ferrini, S.9
-
99
-
-
0029880032
-
Anti-CD30 (BER=H2) immunotoxins containing the type-1 ribosome-inactivating proteins momordin and PAP-S (pokeweed antiviral protein from seeds) display powerful antitumour activity against CD30+ tumour cells in vitro and in SCID mice
-
A. Terenzi A. Bolognesi L. Pasqualucci L. Flenghi S. Pileri H. Stein M. Kadin B. Bigerna L. Polito P.L. Tazzari M.F. Martelli F. Stirpe B. Falini Anti-CD30 (BER=H2) immunotoxins containing the type-1 ribosome-inactivating proteins momordin and PAP-S (pokeweed antiviral protein from seeds) display powerful antitumour activity against CD30+ tumour cells in vitro and in SCID mice Br. J. Haematol 92 1996 872 879
-
(1996)
Br. J. Haematol
, vol.92
, pp. 872-879
-
-
Terenzi, A.1
Bolognesi, A.2
Pasqualucci, L.3
Flenghi, L.4
Pileri, S.5
Stein, H.6
Kadin, M.7
Bigerna, B.8
Polito, L.9
Tazzari, P.L.10
Martelli, M.F.11
Stirpe, F.12
Falini, B.13
-
100
-
-
0037312490
-
Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein
-
J. Thorburn A.E. Frankel A. Thorburn Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein Clin. Cancer Res 9 2003 861 865
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 861-865
-
-
Thorburn, J.1
Frankel, A.E.2
Thorburn, A.3
-
101
-
-
0019510072
-
Cytotoxicity acquired by conjugation of an anti-Thy1.1 monoclonal antibody and the ribosome-inactivating protein, gelonin
-
P.E. Thorpe A.N. Brown W.C. Ross A.J. Cumber S.I. Detre D.C. Edwards A.J. Davies F. Stirpe Cytotoxicity acquired by conjugation of an anti-Thy1.1 monoclonal antibody and the ribosome-inactivating protein, gelonin Eur. J. Biochem 116 1981 447 454
-
(1981)
Eur. J. Biochem
, vol.116
, pp. 447-454
-
-
Thorpe, P.E.1
Brown, A.N.2
Ross, W.C.3
Cumber, A.J.4
Detre, S.I.5
Edwards, D.C.6
Davies, A.J.7
Stirpe, F.8
-
102
-
-
0036186902
-
Difference in CD22 molecules in human B cells and basophils
-
K. Toba H. Hanawa I. Fuse M. Sakaue K. Watanabe Y. Uesugi W. Higuchi M. Takahashi Y. Aizawa Difference in CD22 molecules in human B cells and basophils Exp. Hematol 30 2002 205 211
-
(2002)
Exp. Hematol
, vol.30
, pp. 205-211
-
-
Toba, K.1
Hanawa, H.2
Fuse, I.3
Sakaue, M.4
Watanabe, K.5
Uesugi, Y.6
Higuchi, W.7
Takahashi, M.8
Aizawa, Y.9
-
103
-
-
0037615112
-
Monoclonal antibody drug immunoconjugates for targeted treatment of cancer
-
P.A. Trail H.D. King G.M. Dubowchik Monoclonal antibody drug immunoconjugates for targeted treatment of cancer Cancer Immunol. Immunother 52 2003 328 337
-
(2003)
Cancer Immunol. Immunother
, vol.52
, pp. 328-337
-
-
Trail, P.A.1
King, H.D.2
Dubowchik, G.M.3
-
104
-
-
18244419889
-
Gemtuzumab ozogamicin
-
C.S. Viele Gemtuzumab ozogamicin Clin. J. Oncol. Nurs 6 2002 298 299 304
-
(2002)
Clin. J. Oncol. Nurs
, vol.6
, pp. 298-299
-
-
Viele, C.S.1
-
105
-
-
0026375173
-
Phase I immunotoxin trial in patients with B-cell lymphoma
-
E.S. Vitetta M. Stone P. Amlot J. Fay R. May M. Till J. Newman P. Clark R. Collins D. Cunningham Phase I immunotoxin trial in patients with B-cell lymphoma Cancer Res 51 1991 4052 4058
-
(1991)
Cancer Res
, vol.51
, pp. 4052-4058
-
-
Vitetta, E.S.1
Stone, M.2
Amlot, P.3
Fay, J.4
May, R.5
Till, M.6
Newman, J.7
Clark, P.8
Collins, R.9
Cunningham, D.10
-
106
-
-
0036667933
-
Gemtuzumab ozogamicin (CMA-676, Mylotarg) for the treatment of CD33+ acute myeloid leukemia
-
I.A. Voutsadakis Gemtuzumab ozogamicin (CMA-676, Mylotarg) for the treatment of CD33+ acute myeloid leukemia Anticancer Drugs 13 2002 685 692
-
(2002)
Anticancer Drugs
, vol.13
, pp. 685-692
-
-
Voutsadakis, I.A.1
-
107
-
-
0023079670
-
The interleukin-2 receptor on normal and malignant lymphocytes
-
T.A. Waldmann The interleukin-2 receptor on normal and malignant lymphocytes Adv. Exp. Med. Biol 213 1987 129 137
-
(1987)
Adv. Exp. Med. Biol
, vol.213
, pp. 129-137
-
-
Waldmann, T.A.1
-
108
-
-
0023622170
-
The role of the multichain IL-2 receptor complex in the control of normal and malignant T-cell proliferation
-
T.A. Waldmann The role of the multichain IL-2 receptor complex in the control of normal and malignant T-cell proliferation Environ. Health Perspect 75 1987 11 15
-
(1987)
Environ. Health Perspect
, vol.75
, pp. 11-15
-
-
Waldmann, T.A.1
-
109
-
-
0027358076
-
Recombinant fusion toxins—a new class of targeted biologic therapeutics
-
T.G. Woodworth J.C. Nichols Recombinant fusion toxins—a new class of targeted biologic therapeutics Cancer Treat. Res 68 1993 145 160
-
(1993)
Cancer Treat. Res
, vol.68
, pp. 145-160
-
-
Woodworth, T.G.1
Nichols, J.C.2
-
110
-
-
0029878810
-
Antileukemic activity of recombinant humanized M195-gelonin immunotoxin in nude mice
-
Y. Xu Q. Xu M.G. Rosenblum D.A. Scheinberg Antileukemic activity of recombinant humanized M195-gelonin immunotoxin in nude mice Leukemia 10 1996 321 326
-
(1996)
Leukemia
, vol.10
, pp. 321-326
-
-
Xu, Y.1
Xu, Q.2
Rosenblum, M.G.3
Scheinberg, D.A.4
-
111
-
-
0028656441
-
Quantitative analysis of protein synthesis inhibition by transferrin-toxin conjugates
-
P.T. Yazdi R.M. Murphy Quantitative analysis of protein synthesis inhibition by transferrin-toxin conjugates Cancer Res 54 1994 6387 6394
-
(1994)
Cancer Res
, vol.54
, pp. 6387-6394
-
-
Yazdi, P.T.1
Murphy, R.M.2
-
112
-
-
0023820894
-
Calicheamicin gamma 1I: An antitumor antibiotic that cleaves double-stranded DNA site specifically
-
N. Zein A.M. Sinha W.J. McGahren G.A. Ellestad Calicheamicin gamma 1I: An antitumor antibiotic that cleaves double-stranded DNA site specifically Science 240 1988 1198 1201
-
(1988)
Science
, vol.240
, pp. 1198-1201
-
-
Zein, N.1
Sinha, A.M.2
McGahren, W.J.3
Ellestad, G.A.4
-
113
-
-
0023511446
-
Markers of differentiated B cell leukaemia: CD22 antibodies and FMC7 react with different molecules
-
H. Zola S.H. Neoh A. Potter J.V. Melo M.S. De Oliveria D. Catovsky Markers of differentiated B cell leukaemia: CD22 antibodies and FMC7 react with different molecules Dis. Markers 5 1987 227 235
-
(1987)
Dis. Markers
, vol.5
, pp. 227-235
-
-
Zola, H.1
Neoh, S.H.2
Potter, A.3
Melo, J.V.4
De Oliveria, M.S.5
Catovsky, D.6
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