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Volumn 9, Issue 2, 1998, Pages 201-207

Interleukin 7 (IL-7) receptor-specific cell killing by DAB389 IL-7: A novel agent for the elimination of IL-7 receptor positive cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEIN;

EID: 0032031693     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9701757     Document Type: Article
Times cited : (21)

References (43)
  • 1
    • 24244463747 scopus 로고
    • In Vitro effects of a recombinant diphtheria-human CD4 fusion toxin on acute and chronically HIV-1 infected cells
    • Aullo, P., Alcani, J., Popoff, M. R., Klatzman, D. R., Murphy, J. R., and Boquet, P. (1992) In Vitro effects of a recombinant diphtheria-human CD4 fusion toxin on acute and chronically HIV-1 infected cells. EMBO J. 12, 921-931.
    • (1992) EMBO J. , vol.12 , pp. 921-931
    • Aullo, P.1    Alcani, J.2    Popoff, M.R.3    Klatzman, D.R.4    Murphy, J.R.5    Boquet, P.6
  • 2
    • 0023845225 scopus 로고
    • Interleukin-2 targeted cytoxicity: Selective action of a diphtheria toxin-related interleukin-2 fusion protein
    • Bacha, P., Waters, C., Williams, J., Murphy, J. R., and Strom, T. B. (1988) Interleukin-2 targeted cytoxicity: selective action of a diphtheria toxin-related interleukin-2 fusion protein. J. Exp. Med. 167, 612-622.
    • (1988) J. Exp. Med. , vol.167 , pp. 612-622
    • Bacha, P.1    Waters, C.2    Williams, J.3    Murphy, J.R.4    Strom, T.B.5
  • 3
    • 0031455167 scopus 로고    scopus 로고
    • Disulfide bond assignment in human interleukin-7 by MALDI mass spectroscopy and site directed cysteine to serine mutational analysis
    • Cosenza, L., Sweeney, E., and Murphy, J. R. (1997) Disulfide bond assignment in human interleukin-7 by MALDI mass spectroscopy and site directed cysteine to serine mutational analysis. J. Biol. Chem. 272, 32995-33000.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32995-33000
    • Cosenza, L.1    Sweeney, E.2    Murphy, J.R.3
  • 4
    • 0027302709 scopus 로고
    • Activation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor on human thymocytes
    • Dadi, H. K., and Roifman, C. M. (1993) Activation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor on human thymocytes. J. Clin. Invest. 92, 1559-1563.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1559-1563
    • Dadi, H.K.1    Roifman, C.M.2
  • 5
    • 0027203229 scopus 로고
    • Interleukin 7 receptor mediates the activation of a phosphatidylinositol-3 kinase in human B-cell precursors
    • Dadi, H. K., Ke, S., and Roifman, C. M. (1993) Interleukin 7 receptor mediates the activation of a phosphatidylinositol-3 kinase in human B-cell precursors. Biochem. Biophys. Res. Commun. 192, 459-464.
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , pp. 459-464
    • Dadi, H.K.1    Ke, S.2    Roifman, C.M.3
  • 6
    • 0025820764 scopus 로고
    • Engagement of interleukin-7 receptor stimulates tyrosine phosphorylation, phosphoinositide turnover and clonal proliferation of human T-lineage acute lymphoblastic leukemia cells
    • Dibirdik, I., Langue, M. C., Ledbetter, J. A., Tuel-Ahlgren, L., Obuz, V., Waddick, K. G., Gajl-Peczalska, K., Schieven, G. L., and Ukun, F. M. (1991) Engagement of interleukin-7 receptor stimulates tyrosine phosphorylation, phosphoinositide turnover and clonal proliferation of human T-lineage acute lymphoblastic leukemia cells. Blood 78, 564-570.
    • (1991) Blood , vol.78 , pp. 564-570
    • Dibirdik, I.1    Langue, M.C.2    Ledbetter, J.A.3    Tuel-Ahlgren, L.4    Obuz, V.5    Waddick, K.G.6    Gajl-Peczalska, K.7    Schieven, G.L.8    Ukun, F.M.9
  • 7
    • 0025784365 scopus 로고
    • Human Interleukin-7 induces proliferation of neoplastic cells from chronic lymphocytic leukemia and acute leukemias
    • Digel, W., Schmid, M., Heil, G., Conrad, P., Gillis, S., and Porzsolt, F. (1991) Human Interleukin-7 induces proliferation of neoplastic cells from chronic lymphocytic leukemia and acute leukemias. Blood 78, 753-759.
    • (1991) Blood , vol.78 , pp. 753-759
    • Digel, W.1    Schmid, M.2    Heil, G.3    Conrad, P.4    Gillis, S.5    Porzsolt, F.6
  • 8
    • 0028874974 scopus 로고
    • Interleukin-7 can induce the activation of Jak I, Jak 3 and STAT 5 proteins in murine T cells
    • Foxwell, B. M. J., Beadling, C., Guschin, D., Kerr, I., and Cantrell, D. (1995) Interleukin-7 can induce the activation of Jak I, Jak 3 and STAT 5 proteins in murine T cells. Eur. J. Immunol. 25, 3041-3046.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3041-3046
    • Foxwell, B.M.J.1    Beadling, C.2    Guschin, D.3    Kerr, I.4    Cantrell, D.5
  • 9
  • 12
    • 0026328791 scopus 로고
    • Diptheria toxin receptor binding domain substitution with interleukin-6: Genetic construction and interleukin-6 receptor specific action of a diphtheria toxin-related interleukin-6 fusion protein
    • Jean, L.-F., and Murphy, J. R. (1992) Diptheria toxin receptor binding domain substitution with interleukin-6: genetic construction and interleukin-6 receptor specific action of a diphtheria toxin-related interleukin-6 fusion protein. Protein Eng. 4, 989-994.
    • (1992) Protein Eng. , vol.4 , pp. 989-994
    • Jean, L.-F.1    Murphy, J.R.2
  • 13
    • 0026655341 scopus 로고
    • Reversion of recombinant toxoids: Mutations in diphtheria toxin that partially compensate for active-site deletions
    • Killeen, K. P., Escuyer, V., Mekalanos, J. J., and Collier, R. J. (1992) Reversion of recombinant toxoids: mutations in diphtheria toxin that partially compensate for active-site deletions. Proc. Natl. Acad. Sci. U.S.A. 89, 6207-6209.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 6207-6209
    • Killeen, K.P.1    Escuyer, V.2    Mekalanos, J.J.3    Collier, R.J.4
  • 14
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 15
    • 0025745412 scopus 로고
    • Interleukin 4 receptor targeted cytotoxicity: Genetic construction and in vivo immunosuppressive activity of a diptheria toxin-related interleukin 4 fusion protein
    • Lakkis, F., Steele, A., Pacheco-Silva, A., Rubin-Kelley, V., Strom, T. B., and Murphy, J. R. (1991) Interleukin 4 receptor targeted cytotoxicity: genetic construction and in vivo immunosuppressive activity of a diptheria toxin-related interleukin 4 fusion protein. Eur. J. Immunol. 21, 2253-2258.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2253-2258
    • Lakkis, F.1    Steele, A.2    Pacheco-Silva, A.3    Rubin-Kelley, V.4    Strom, T.B.5    Murphy, J.R.6
  • 19
    • 0016010643 scopus 로고
    • Protein chain initiation in wheat embryo
    • K. Moldave and L. Grossman, Eds. Academic Press, San Diego
    • Marcus, A., Seal, S., and Weeks, D. (1974) Protein chain initiation in wheat embryo. In Methods in Enzymology (K. Moldave and L. Grossman, Eds.) Vol. 30, Academic Press, San Diego.
    • (1974) Methods in Enzymology , vol.30
    • Marcus, A.1    Seal, S.2    Weeks, D.3
  • 21
    • 0019497198 scopus 로고
    • Kinetics of adenosinediphospho-ribosylation of elongation factor 2 in cells exposed to diphtheria toxin
    • Moynihan, M., and Pappenheimer, A. M., Jr. (1981) Kinetics of adenosinediphospho-ribosylation of elongation factor 2 in cells exposed to diphtheria toxin. Infect. Immun. 32, 575-582.
    • (1981) Infect. Immun. , vol.32 , pp. 575-582
    • Moynihan, M.1    Pappenheimer A.M., Jr.2
  • 22
    • 0029383734 scopus 로고
    • Targeting diphtheria toxin to growth factor receptors
    • Murphy, J. R., and vanderSpek, J. C. (1995) Targeting diphtheria toxin to growth factor receptors. Cancer Biol. 6, 259-267.
    • (1995) Cancer Biol. , vol.6 , pp. 259-267
    • Murphy, J.R.1    VanderSpek, J.C.2
  • 23
    • 0008530328 scopus 로고
    • Genetic construction, expression and melanoma-selective cytotoxicity of a diphtheria toxin α-melanocyte stimulating hormone fusion protein
    • Murphy, J. R., Bishai, W., Bowoski, M., Miyanohara, A., Boyd, J., and Nagle, S. (1986) Genetic construction, expression and melanoma-selective cytotoxicity of a diphtheria toxin α-melanocyte stimulating hormone fusion protein. Proc. Natl. Acad. Sci. U.S.A. 83, 8258-8262.
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 8258-8262
    • Murphy, J.R.1    Bishai, W.2    Bowoski, M.3    Miyanohara, A.4    Boyd, J.5    Nagle, S.6
  • 24
    • 0028955102 scopus 로고
    • Regualtion of JAK3 expression in human monocytes: Phosphorylation in response to interleukins 2, 4, and 7
    • Musso, T., Johnston, J. A., Linnekin, D., Varesio, L., Rowe, T. K., O'Shea, J. J., and McVicar, D. W. (1995) Regualtion of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7. J. Exp. Med. 181, 1425-1431.
    • (1995) J. Exp. Med. , vol.181 , pp. 1425-1431
    • Musso, T.1    Johnston, J.A.2    Linnekin, D.3    Varesio, L.4    Rowe, T.K.5    O'Shea, J.J.6    McVicar, D.W.7
  • 26
    • 0027751556 scopus 로고
    • Interleukin-2 receptor γ chain: A functional component of the interleukin-7 receptor
    • Noguchi, M., Nakamura, Y., Russell, S. M., Ziegler, S. F., Tsang, M., Cao, X., and Leonard, W. J. (1993) Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor. Science 262, 1877-1880.
    • (1993) Science , vol.262 , pp. 1877-1880
    • Noguchi, M.1    Nakamura, Y.2    Russell, S.M.3    Ziegler, S.F.4    Tsang, M.5    Cao, X.6    Leonard, W.J.7
  • 28
    • 0023884998 scopus 로고
    • Stromal cell lines which support lymphocyte growth: Characterisation, sensitivity to radiation and responsiveness to growth factors
    • Pietrangeli, C., Hayashi, S., and Kincade, P. (1988) Stromal cell lines which support lymphocyte growth: Characterisation, sensitivity to radiation and responsiveness to growth factors. Eur. J. Immunol. 18, 863.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 863
    • Pietrangeli, C.1    Hayashi, S.2    Kincade, P.3
  • 29
    • 0026586152 scopus 로고
    • IL-7 receptor mediates tyrosine phosphorylation but does not activate the phosphatidylinositol-phospholipase C-γ1 pathway
    • Roifman, C. M., Wang, G., Freedman, M., and Pan, Z. (1992) IL-7 receptor mediates tyrosine phosphorylation but does not activate the phosphatidylinositol-phospholipase C-γ1 pathway. J. Immunol. 148, 1136-1142.
    • (1992) J. Immunol. , vol.148 , pp. 1136-1142
    • Roifman, C.M.1    Wang, G.2    Freedman, M.3    Pan, Z.4
  • 31
    • 0015522959 scopus 로고
    • Protein chain initiation in wheat embryo. Resolution and function of the soluble factors
    • Seal, S., Bewley, J., and Marcus, A. (1972) Protein chain initiation in wheat embryo. Resolution and function of the soluble factors J. Biol. Chem. 247, 2592-2597.
    • (1972) J. Biol. Chem. , vol.247 , pp. 2592-2597
    • Seal, S.1    Bewley, J.2    Marcus, A.3
  • 32
    • 0028236916 scopus 로고
    • Activation of src family kinases in human pre-B cells by IL-7
    • Seckinger, P., and Fougereau, M. (1994) Activation of src family kinases in human pre-B cells by IL-7. J. Immunol. 153, 97-109.
    • (1994) J. Immunol. , vol.153 , pp. 97-109
    • Seckinger, P.1    Fougereau, M.2
  • 34
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 37
    • 0025836451 scopus 로고
    • Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes
    • Uckun, F. M., Tuel-Alghren, L., Obuz, V., Smith, R., Dibirdik, I., Hanson, M., Chandan-Langli, M., and Ledbetter, J. A. (1991b) Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes. Proc. Natl. Acad. Sci. U.S.A. 88, 6323-6327.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 6323-6327
    • Uckun, F.M.1    Tuel-Alghren, L.2    Obuz, V.3    Smith, R.4    Dibirdik, I.5    Hanson, M.6    Chandan-Langli, M.7    Ledbetter, J.A.8
  • 40
    • 0025287153 scopus 로고
    • Interleukin-2 receptor targeted cytotoxicity: Receptor binding requirements for entry of IL-2 toxin into cells
    • Waters, C. A., Schimke, P., Snider, C. E., Itoh, K., Smith, K. A., Nichols, J. C., Strom, T. B., and Murphy, J. R. (1990) Interleukin-2 receptor targeted cytotoxicity: receptor binding requirements for entry of IL-2 toxin into cells. Eur. J. Immunol. 20, 785-791.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 785-791
    • Waters, C.A.1    Schimke, P.2    Snider, C.E.3    Itoh, K.4    Smith, K.A.5    Nichols, J.C.6    Strom, T.B.7    Murphy, J.R.8
  • 41
    • 0023529699 scopus 로고
    • Diphtheria toxin receptor binding domain substitution with interleukin-2: Genetic construction and properties of a diphtheria toxin-related interleukin 2 fusion protein
    • Williams, D. P., Parker, K., Bacha, P., Bishai, W., Borowski, M., Genbauffe, F., Strom, T. B., and Murphy, J. R. (1987) Diphtheria toxin receptor binding domain substitution with interleukin-2: Genetic construction and properties of a diphtheria toxin-related interleukin 2 fusion protein. Protein Eng. 1, 493-498.
    • (1987) Protein Eng. , vol.1 , pp. 493-498
    • Williams, D.P.1    Parker, K.2    Bacha, P.3    Bishai, W.4    Borowski, M.5    Genbauffe, F.6    Strom, T.B.7    Murphy, J.R.8
  • 42
    • 0027298402 scopus 로고
    • Early clinical studies of IL-2 fusion toxin in patients with severe rheumatoid arthritis and recent onset insulin-dependent Diabetes Mellitus
    • Woodworth, T. G. (1993) Early clinical studies of IL-2 fusion toxin in patients with severe rheumatoid arthritis and recent onset insulin-dependent Diabetes Mellitus. Clin. Exp. Rheumatol. 11 (Suppl. 8), S177-S180.
    • (1993) Clin. Exp. Rheumatol. , vol.11 , Issue.8 SUPPL.
    • Woodworth, T.G.1
  • 43
    • 0018167496 scopus 로고
    • One molecule of diphtheria toxin fragment a introduced into a cell can kill the cell
    • Yamaizumi, M., Mekada, E., Uchida, T., and Okada, Y. (1978) One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell 15, 245-250.
    • (1978) Cell , vol.15 , pp. 245-250
    • Yamaizumi, M.1    Mekada, E.2    Uchida, T.3    Okada, Y.4


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