메뉴 건너뛰기




Volumn 26, Issue 2, 2004, Pages 57-65

Mechanism of glutamine-mediated amelioration of lipopolysaccharide-induced IL-8 production in Caco-2 cells

Author keywords

Caco 2 cells; Gln; Glutamine; IL 8; Lipopolysaccharide; LPS; MAPK; Methionine sulfoximine; Mitogen activated protein kinase; MS; NF B; Nuclear factor kappa B; Signal transducer and activator of transcription 4; STAT 4

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; GLUTAMATE AMMONIA LIGASE; GLUTAMINE; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; METHIONINE SULFOXIMINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT4 PROTEIN; TRANSCRIPTION FACTOR;

EID: 1642634629     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2003.12.008     Document Type: Article
Times cited : (41)

References (40)
  • 1
    • 0027146545 scopus 로고
    • Differential cytokine expression by human intestinal epithelial cell lines: Regulated expression of interleukin 8
    • Eckmann L., Jung H.C., Schurer-Maly C., Panja A., Morzycka-Wroblewska E., Kagnoff M.F. Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8. Gastroenterology. 105:1993;1689-1697.
    • (1993) Gastroenterology , vol.105 , pp. 1689-1697
    • Eckmann, L.1    Jung, H.C.2    Schurer-Maly, C.3    Panja, A.4    Morzycka-Wroblewska, E.5    Kagnoff, M.F.6
  • 2
    • 0034039543 scopus 로고    scopus 로고
    • Role of nutrients and bacterial colonization in the development of intestinal host defense
    • Walker W.A. Role of nutrients and bacterial colonization in the development of intestinal host defense. J Pediatr Gastroenterol Nutr. 30:2000;S2-S7.
    • (2000) J Pediatr Gastroenterol Nutr , vol.30 , pp. 2-S7
    • Walker, W.A.1
  • 3
    • 0034829818 scopus 로고    scopus 로고
    • Chemokines in pathology and medicine
    • Baggiolini M. Chemokines in pathology and medicine. J Intern Med. 250:2001;91-104.
    • (2001) J Intern Med , vol.250 , pp. 91-104
    • Baggiolini, M.1
  • 4
    • 0034928912 scopus 로고    scopus 로고
    • The role of inflammation in the development of chronic lung disease in neonates
    • De Dooy J.J., Mahieu L.M., Van Bever H.P. The role of inflammation in the development of chronic lung disease in neonates. Eur J Pediatr. 160:2001;457-463.
    • (2001) Eur J Pediatr , vol.160 , pp. 457-463
    • De Dooy, J.J.1    Mahieu, L.M.2    Van Bever, H.P.3
  • 5
    • 0034885610 scopus 로고    scopus 로고
    • Symposium on "evidence-based nutrition", nutrition modulation of immune function
    • Grimble R.F. Symposium on "evidence-based nutrition", nutrition modulation of immune function. Proc Nutr Soc. 60:2001;389-397.
    • (2001) Proc Nutr Soc , vol.60 , pp. 389-397
    • Grimble, R.F.1
  • 7
    • 0036361858 scopus 로고    scopus 로고
    • Glutamine metabolism in the fetus and critically ill low birth weight neonate
    • Neu J., Auestad N., DeMarco V.G. Glutamine metabolism in the fetus and critically ill low birth weight neonate. Adv Pediatr. 49:2002.
    • (2002) Adv Pediatr , vol.49
    • Neu, J.1    Auestad, N.2    Demarco, V.G.3
  • 8
    • 0035168102 scopus 로고    scopus 로고
    • Glutamine administration reduces gram-negative bacteria in severely burned patients: A prospective, randomized, double-blind trial versus isonitrogenous control
    • Wischmeyer P.E., Lynch J., Liedel J., Wolfson R., Riehm J., Gottlieb L., et al. Glutamine administration reduces gram-negative bacteria in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control. Crit Care Med. 29:2001;2075-2080.
    • (2001) Crit Care Med , vol.29 , pp. 2075-2080
    • Wischmeyer, P.E.1    Lynch, J.2    Liedel, J.3    Wolfson, R.4    Riehm, J.5    Gottlieb, L.6
  • 9
    • 0032487082 scopus 로고    scopus 로고
    • Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma
    • [see comments]
    • Houdijk A.P., Rijnsburger E.R., Jansen J., Wesdorp R.I., Weiss J.K., McCamish M.A., et al. Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma. [see comments] Lancet. 352:1998;772-776.
    • (1998) Lancet , vol.352 , pp. 772-776
    • Houdijk, A.P.1    Rijnsburger, E.R.2    Jansen, J.3    Wesdorp, R.I.4    Weiss, J.K.5    McCamish, M.A.6
  • 10
    • 0027102761 scopus 로고
    • Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study
    • Ziegler T.R., Young L.S., Benfell K., Scheltinga M., Hortos K., Bye R., et al. Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study. Ann Intern Med. 116:1992;821-828.
    • (1992) Ann Intern Med , vol.116 , pp. 821-828
    • Ziegler, T.R.1    Young, L.S.2    Benfell, K.3    Scheltinga, M.4    Hortos, K.5    Bye, R.6
  • 11
    • 0035513751 scopus 로고    scopus 로고
    • Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia
    • Wischmeyer P.E., Kahana M., Wolfson R., Ren H., Musch M.M., Chang E.B. Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia. Shock. 16:2001;393-402.
    • (2001) Shock , vol.16 , pp. 393-402
    • Wischmeyer, P.E.1    Kahana, M.2    Wolfson, R.3    Ren, H.4    Musch, M.M.5    Chang, E.B.6
  • 13
    • 0035316623 scopus 로고    scopus 로고
    • TPN decreases IL-4 and IL-10 mRNA expression in lipopolysaccharide stimulated intestinal lamina propria cells but glutamine supplementation preserves the expression
    • Fukatsu K., Kudsk K.A., Zarzaur B.L., Wu Y., Hanna M.K., DeWitt R.C. TPN decreases IL-4 and IL-10 mRNA expression in lipopolysaccharide stimulated intestinal lamina propria cells but glutamine supplementation preserves the expression. Shock. 15:2001;318-322.
    • (2001) Shock , vol.15 , pp. 318-322
    • Fukatsu, K.1    Kudsk, K.A.2    Zarzaur, B.L.3    Wu, Y.4    Hanna, M.K.5    Dewitt, R.C.6
  • 14
    • 17544365995 scopus 로고    scopus 로고
    • The I B/NF-B system: A key determinant of mucosal inflammation and protection
    • Jobin C., Sartor R.B. The I B/NF-B system: a key determinant of mucosal inflammation and protection. Am J Physiol Cell Physiol. 278:2000;C451-C462.
    • (2000) Am J Physiol Cell Physiol , vol.278 , pp. 451-C462
    • Jobin, C.1    Sartor, R.B.2
  • 16
    • 0034733041 scopus 로고    scopus 로고
    • Stimulation of NF-B activity by multiple signaling pathways requires PAK1
    • Frost J.A., Swantek J.L., Stippec S., Yin M.J., Gaynor R., Cobb M.H. Stimulation of NF-B activity by multiple signaling pathways requires PAK1. J Biol Chem. 276:2000;19693-19699.
    • (2000) J Biol Chem , vol.276 , pp. 19693-19699
    • Frost, J.A.1    Swantek, J.L.2    Stippec, S.3    Yin, M.J.4    Gaynor, R.5    Cobb, M.H.6
  • 17
    • 0038384141 scopus 로고    scopus 로고
    • Glutamine decreases lipopolysaccharide-induced IL-8 production in Caco-2 cells through a non-NF-kappaB p50 mechanism
    • Huang Y., Li N., Liboni K., Neu J. Glutamine decreases lipopolysaccharide-induced IL-8 production in Caco-2 cells through a non-NF-kappaB p50 mechanism. Cytokine. 22:2003;77-83.
    • (2003) Cytokine , vol.22 , pp. 77-83
    • Huang, Y.1    Li, N.2    Liboni, K.3    Neu, J.4
  • 18
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud J., Gupta S., Rogers J.S., Dickens M., Han J., Ulevitch R.J., et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem. 270:1995;7420-7426.
    • (1995) J Biol Chem , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6
  • 19
    • 0030909506 scopus 로고    scopus 로고
    • The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells
    • Briske-Anderson M.J., Finley J.W., Newman S.M. The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells. Proc Soc Exp Biol Med. 214:1997;248-257.
    • (1997) Proc Soc Exp Biol Med , vol.214 , pp. 248-257
    • Briske-Anderson, M.J.1    Finley, J.W.2    Newman, S.M.3
  • 20
    • 0035870276 scopus 로고    scopus 로고
    • Down-regulation of beta-catenin TCF signaling is linked to colonic epithelial cell differentiation
    • Mariadason J.M., Bordonaro M., Aslam F., Shi L., Kuraguchi M., Velcich A., et al. Down-regulation of beta-catenin TCF signaling is linked to colonic epithelial cell differentiation. Cancer Res. 61:2001;3465-3471.
    • (2001) Cancer Res , vol.61 , pp. 3465-3471
    • Mariadason, J.M.1    Bordonaro, M.2    Aslam, F.3    Shi, L.4    Kuraguchi, M.5    Velcich, A.6
  • 21
    • 0033276680 scopus 로고    scopus 로고
    • Butyrate switches the pattern of chemokine secretion by intestinal epithelial cells through histone acetylation
    • Fusunyan R.D., Quinn J.J., Fujimoto M., MacDermott R.P., Sanderson I.R. Butyrate switches the pattern of chemokine secretion by intestinal epithelial cells through histone acetylation. Mol Med. 5:1999;631-640.
    • (1999) Mol Med , vol.5 , pp. 631-640
    • Fusunyan, R.D.1    Quinn, J.J.2    Fujimoto, M.3    MacDermott, R.P.4    Sanderson, I.R.5
  • 22
    • 0031039936 scopus 로고    scopus 로고
    • The gut as a source of inflammatory cytokines after stimulation with endotoxin
    • Ogle C.K., Guo X.L., Hasselgren P.O., Ogle J.D., Alexander J.W. The gut as a source of inflammatory cytokines after stimulation with endotoxin. Eur J Surg. 163:1997;45-51.
    • (1997) Eur J Surg , vol.163 , pp. 45-51
    • Ogle, C.K.1    Guo, X.L.2    Hasselgren, P.O.3    Ogle, J.D.4    Alexander, J.W.5
  • 23
    • 0002647979 scopus 로고    scopus 로고
    • Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures
    • Haller D., Bode C., Hammes W.P., Pfeifer A.M.A., Schiffrin E.J., Blum S. Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures. Gut. 47:2000;79-87.
    • (2000) Gut , vol.47 , pp. 79-87
    • Haller, D.1    Bode, C.2    Hammes, W.P.3    Pfeifer, A.M.A.4    Schiffrin, E.J.5    Blum, S.6
  • 24
    • 0027940046 scopus 로고
    • Colonic epithelial cell lines as a source of interleukin-8: Stimulation by inflammatory cytokines and bacterial lipopolysaccharide
    • Schuerer-Maly C.C., Eckmann L., Kagnoff M.F., Falco M.T., Maly F.E. Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide. Immunology. 81:1994;85-91.
    • (1994) Immunology , vol.81 , pp. 85-91
    • Schuerer-Maly, C.C.1    Eckmann, L.2    Kagnoff, M.F.3    Falco, M.T.4    Maly, F.E.5
  • 25
    • 0034705053 scopus 로고    scopus 로고
    • Inflammation in the developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis
    • Nanthakumar N.N., Fusunyan R.D., Sanderson I., Walker W.A. Inflammation in the developing human intestine: a possible pathophysiologic contribution to necrotizing enterocolitis. Proc Natl Acad Sci U S A. 97:2000;6043-6048.
    • (2000) Proc Natl Acad Sci U S a , vol.97 , pp. 6043-6048
    • Nanthakumar, N.N.1    Fusunyan, R.D.2    Sanderson, I.3    Walker, W.A.4
  • 26
    • 0028853750 scopus 로고
    • The role of pro-inflammatory and immunoregulatory cytokines in the pathogenesis of ulcerative colitis
    • Murata Y., Ishiguro Y., Itoh J., Munakata A., Yoshida Y. The role of pro-inflammatory and immunoregulatory cytokines in the pathogenesis of ulcerative colitis. Gastroenterol Clin North Am J. 30:(Suppl 8):1995;56-60.
    • (1995) Gastroenterol Clin North Am J , vol.30 , Issue.SUPPL. 8 , pp. 56-60
    • Murata, Y.1    Ishiguro, Y.2    Itoh, J.3    Munakata, A.4    Yoshida, Y.5
  • 27
    • 0036019501 scopus 로고    scopus 로고
    • Glutamine decreased interleukin-8 and interleukin-6 but not nitric oxide and prostaglandins E2 production by human gut in vitro
    • Coeffier M., Marion R., Leplingard A., Lerebours E., Ducrotte P., Dechelotte P. Glutamine decreased interleukin-8 and interleukin-6 but not nitric oxide and prostaglandins E2 production by human gut in vitro. Cytokine. 18:2002.
    • (2002) Cytokine , vol.18
    • Coeffier, M.1    Marion, R.2    Leplingard, A.3    Lerebours, E.4    Ducrotte, P.5    Dechelotte, P.6
  • 28
    • 0032031166 scopus 로고    scopus 로고
    • Glutamine-supplemented total parenteral nutrition reduces blood mononuclear cell interleukin-8 release in severe acute pancreatitis
    • de Beaux A.C., O'Riordain M.G., Ross J.A., Jodozi L., Carter D.C., Fearon K.C. Glutamine-supplemented total parenteral nutrition reduces blood mononuclear cell interleukin-8 release in severe acute pancreatitis. Nutrition. 14:1998;261-265.
    • (1998) Nutrition , vol.14 , pp. 261-265
    • De Beaux, A.C.1    O'Riordain, M.G.2    Ross, J.A.3    Jodozi, L.4    Carter, D.C.5    Fearon, K.C.6
  • 29
    • 9844228499 scopus 로고    scopus 로고
    • Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor alpha production in trinitrobenzene sulphonic acid induced colitis
    • Ameho C.K., Adjei A.A., Harrison E.K., Takeshita K., Morioka T., Arakaki Y., et al. Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor alpha production in trinitrobenzene sulphonic acid induced colitis. Gut. 41:1997;487-493.
    • (1997) Gut , vol.41 , pp. 487-493
    • Ameho, C.K.1    Adjei, A.A.2    Harrison, E.K.3    Takeshita, K.4    Morioka, T.5    Arakaki, Y.6
  • 31
    • 0038339459 scopus 로고    scopus 로고
    • Glutamine preserves protein synthesis and paracellular permeability in Caco-2 cells submitted to "luminal fasting"
    • Le Bacquer O., Laboisse C., Darmaun D. Glutamine preserves protein synthesis and paracellular permeability in Caco-2 cells submitted to "luminal fasting" Am J Physiol Gastrointest Liver Physiol. 285:2003;G128-G136.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285 , pp. 128-G136
    • Le Bacquer, O.1    Laboisse, C.2    Darmaun, D.3
  • 32
    • 0025475371 scopus 로고
    • Is glutamine a conditionally essential amino acid?
    • Lacey J.M., Wilmore D.W. Is glutamine a conditionally essential amino acid? Nutr Rev. 48:1990;297-309.
    • (1990) Nutr Rev , vol.48 , pp. 297-309
    • Lacey, J.M.1    Wilmore, D.W.2
  • 33
    • 0030844172 scopus 로고    scopus 로고
    • Enteral glutamine supplementation for very low birth weight infants decreases morbidity
    • Neu J., Roig J.C., Meetze W.H., Veerman M., Carter C., Millsaps M., et al. Enteral glutamine supplementation for very low birth weight infants decreases morbidity. J Pediatr. 131:1997;691-699.
    • (1997) J Pediatr , vol.131 , pp. 691-699
    • Neu, J.1    Roig, J.C.2    Meetze, W.H.3    Veerman, M.4    Carter, C.5    Millsaps, M.6
  • 34
    • 0011111413 scopus 로고    scopus 로고
    • Glutamine signaling in intestinal cells
    • Rhoads J.M. Glutamine signaling in intestinal cells. J Parenter Enteral Nutr. 1999;S38-S40.
    • (1999) J Parenter Enteral Nutr , pp. 38-S40
    • Rhoads, J.M.1
  • 35
    • 0031006025 scopus 로고    scopus 로고
    • L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases
    • Rhoads J.M., Argenzio R.A., Chen W., Rippe R.A., Westwick J.K., Cox A.D., et al. L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases. Am J Physiol. 272:1997.
    • (1997) Am J Physiol , vol.272
    • Rhoads, J.M.1    Argenzio, R.A.2    Chen, W.3    Rippe, R.A.4    Westwick, J.K.5    Cox, A.D.6
  • 36
    • 0035928897 scopus 로고    scopus 로고
    • So many ligands, so few transcription factors: A new paradigm for signaling through the STAT transcription factors
    • Subramaniam P.S., Torres B.A., Johnson H.M. So many ligands, so few transcription factors: a new paradigm for signaling through the STAT transcription factors. Cytokine. 15:2001;175-187.
    • (2001) Cytokine , vol.15 , pp. 175-187
    • Subramaniam, P.S.1    Torres, B.A.2    Johnson, H.M.3
  • 37
    • 0036104077 scopus 로고    scopus 로고
    • Up-regulation of IL-18 and IL-12 in the ileum of neonatal rats with necrotizing enterocolitis
    • Halpern M.D., Holubec H., Dominguez J.A., Williams C.S., Meza Y.G., McWilliam D.L., et al. Up-regulation of IL-18 and IL-12 in the ileum of neonatal rats with necrotizing enterocolitis. Pediatr Res. 51:2002;733-739.
    • (2002) Pediatr Res , vol.51 , pp. 733-739
    • Halpern, M.D.1    Holubec, H.2    Dominguez, J.A.3    Williams, C.S.4    Meza, Y.G.5    McWilliam, D.L.6
  • 39
    • 0033558364 scopus 로고    scopus 로고
    • Cutting edge: Chronic intestinal inflammation in STAT-4 transgenic mice: Characterization of disease and adoptive transfer by TNF- plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens
    • Wirtz S., Finotto S., Kanzler S., Lohse A.W., Blessing M., Lehr H.A., et al. Cutting edge: chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF- plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens. J Immunol. 162:1999;1885-1888.
    • (1999) J Immunol , vol.162 , pp. 1885-1888
    • Wirtz, S.1    Finotto, S.2    Kanzler, S.3    Lohse, A.W.4    Blessing, M.5    Lehr, H.A.6
  • 40
    • 0035911232 scopus 로고    scopus 로고
    • Pivotal role of signal transducer and activator of transcription (Stat)4 and Stat6 in the innate immune response during sepsis
    • Matsukawa A., Kaplan M.H., Hogaboam C.M., Lukacsa N.W., Kunkel S.L. Pivotal role of signal transducer and activator of transcription (Stat)4 and Stat6 in the innate immune response during sepsis. J Exp Med. 103:2001;679-688.
    • (2001) J Exp Med , vol.103 , pp. 679-688
    • Matsukawa, A.1    Kaplan, M.H.2    Hogaboam, C.M.3    Lukacsa, N.W.4    Kunkel, S.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.