Glutamine administration reduces Gram-negative bacteremia in severely burned patients: A prospective, randomized, double-blind trial versus isonitrogenous control

Critical Care Medicine

Volumn 29, Issue 11, 2001, Pages 2075-2080

  Wischmeyer, Paul E ^a,b   Lynch, James ^a   Liedel, Jennifer ^a   Wolfson, Rachel ^a   Riehm, Jacob ^a   Gottlieb, Lawrence ^a   Kahana, Madelyn ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Amino acid; Burn injury; Gram negative bacteremia; Intensive care unit; Nutrition; Outcome study

Indexed keywords

FREAMINE; GLUTAMINE; PREALBUMIN; TRANSFERRIN;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BLOOD CULTURE; BODY SURFACE; BURN; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; FULL THICKNESS SKIN GRAFT; GRAM NEGATIVE INFECTION; HUMAN; INCIDENCE; INTENSIVE CARE UNIT; MALE; MORBIDITY; MORTALITY; NUTRITIONAL STATUS; OUTCOMES RESEARCH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUPPLEMENTATION; TRANSFERRIN BLOOD LEVEL;

EID: 0035168102     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200111000-00006     Document Type: Article

References (21)

1. The management of burns
2. An evaluation of risk factors for mortality after burn trauma and the identification of gender-dependent differences in outcomes
3. The challenge of burns
4. Burn injury
5. Advances in the treatment of burn patients
6. Trauma, shock, and gut translocation
7. Relationship between extent of burn injury and magnitude of microbial translocation from the intestine
8. The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells
9. Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats
10. Oral glutamine decreases bacterial translocation and improves survival in experimental gut origin sepsis
11. Supplementation of an elemental enteral diet with alanyl-glutamine decreases bacterial translocation in burned mice
12. Glutamine induces heat shock protein and protects against endotoxin shock in the rat
13. Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia
14. Sodium arsenite induces the stress response in the gut and decreases bacterial translocation in a burned mouse model with gut-derived sepsis
15. Clinical and metabolic efficacy of glutamine supplemented parental nutrition after bone marrow transplantation
16. Randomized trial of glutamine-enriched nutrition on infectious morbidity in patients with multiple trauma
17. Glutamine kinetics in burn patients
18. Six-month outcome of critically ill patients given glutamine supplemented parenteral nutrition
19. Enteral glutamine supplementation for very low birth weight infants decreases morbidity
20. Randomized clinical outcome study of critically ill patients given glutamine-supplemented enteral nutrition
21. Glutamine dipeptide-supplemented parenteral nutrition reverses gut atrophy, disaccharidase enzyme activity, and absorption in rats