Glutamine decreases interleukin-8 and interleukin-6 but not nitric oxide and prostaglandins E2 production by human gut in-vitro

Cytokine

Volumn 18, Issue 2, 2002, Pages 92-97

  Coëffier, Moïse ^a,b   Marion, Rachel ^a,b   Leplingard, Antony ^a,b   Lerebours, Eric ^a,b   Ducrotté, Philippe ^a,b   Déchelotte, Pierre ^a,b  

^a Faculté de Médecine Pharmacie   (France)

^b Institut Fédératif de Recherches Multidisciplinaires Sur Les Peptides   (France)

Author keywords

Cytokines; Eicosanoids; Glutamine; Gut; Nitric oxide

Indexed keywords

CYCLOOXYGENASE 2; GLUTAMINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; ISOENZYME; MEMBRANE PROTEIN; NOS2A PROTEIN, HUMAN; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; CYTOKINE PRODUCTION; DUODENUM BIOPSY; ENDOSCOPY; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IN VITRO STUDY; NORMAL HUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BIOPSY; CELL CULTURE; CULTURE MEDIUM; DRUG EFFECT; DUODENUM; GENETIC TRANSCRIPTION; GENETICS; KINETICS; METABOLISM;

ADULT; BIOPSY; CELLS, CULTURED; CULTURE MEDIA; CYCLOOXYGENASE 2; DINOPROSTONE; DUODENUM; GLUTAMINE; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; ISOENZYMES; KINETICS; MEMBRANE PROTEINS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0036019501     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2002.1027     Document Type: Article

References (29)

1. Cytokines and growth factors in inflammatory bowel disease
2. Spectrum of cytokine gene expression in intestinal mucosal lesions of Crohn's disease and ulcerative colitis
3. Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease
4. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease
5. Nutritional support
6. Effect of free glutamine and glutamine-alanine dipeptide on mucosal proliferation of the human ileum and colon
7. Effects of enteral glutamine on gut mucosal protein synthesis in healthy humans receiving glucocorticoids
8. Glutamine and the preservation of gut integrity
9. Prophylactic effect of dietary glutamine supplementation on interleukin-8 and tumor necrosis factor-α production in trinitrobenzene sulphonic acid induced colitis
10. Glutamine-enriched total parenteral nutrition maintains intestinal interleukin-4 and mucosal immunoglobulin A levels
11. Modulation of organ ICAM-1 expression during IV-TPN with glutamine and bombesin
12. Dietary glutamine supplementation reduces plasma nitrate levels in rats
13. Influence of glutamine on cytokine production in human gut in-vitro
14. Cytokine production by human peripheral blood mononuclear cells: Differential sensitivity to glutamine availability
15. Synthesis of interleukin-1β and interleukin-6 by stimulated rat peritoneal macrophages: Modulation by glutamine
16. 2 thermogenesis by glycyl-glutamine, a pro-opiomelanocortin-derived peptide
17. Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease
18. Nitric oxide. II. Nitric oxide protects in intestinal inflammation
19. Evidence for an acute phase response in human intestinal epithelium
20. Glutamine accelerates interleukin-6 production by rat peritoneal macrophages in culture
21. Glutamine dipeptides supplemented parenteral nutrition reverses gut mucosal structure and inteleukin-6 release of rat intestinal mononuclear cells after hemorrhagic shock
22. Mucosal interleukin-8 is involved in neutrophil migration and binding to extracellular matrix in inflammatory bowel disease
23. Neutrophil apoptosis is delayed in patients with inflammatory bowel disease
24. Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis
25. Review article: Chemokine production by human intestinal epithelial cells: A therapeutic target in inflammatory bowel disease?
26. Effect of glutamine on leucine metabolism in humans
27. Inflammation in developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis
28. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chlorophorm extraction
29. Increase in cyclooxygenase-2 and NO-synthase-2 mRNAs in pouchitis without modification of inducible enzyme heme-oxygenase-1