메뉴 건너뛰기




Volumn 65, Issue 8, 2003, Pages 1251-1259

Cloning and characterisation of the first drug-metabolising canine UDP-glucuronosyltransferase of the 2B subfamily

Author keywords

Dog UGT2B31; Morphine glucuronidation; Rat UGT2B1; UDP glucuronosyltransferase; UGT activity; UGT2B7

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; GLUCURONOSYLTRANSFERASE; MORPHINE 3 GLUCURONIDE; OPIATE; PHENOL DERIVATIVE;

EID: 0037446386     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00064-9     Document Type: Article
Times cited : (21)

References (24)
  • 2
    • 0001177611 scopus 로고
    • The uridine diphosphate glucuronosyltransferase multigene family: Function and regulation
    • Frederic C, Kaufsan FC, editors. New York: Springer
    • Clarke DJ, Buchell B. The uridine diphosphate glucuronosyltransferase multigene family: function and regulation. In: Frederic C, Kaufsan FC, editors. Handbook of experimental pharmacology. New York: Springer; 1994. p. 3-43.
    • (1994) Handbook of Experimental Pharmacology , pp. 3-43
    • Clarke, D.J.1    Buchell, B.2
  • 3
    • 0035313896 scopus 로고    scopus 로고
    • Screening for human ADME/Tox drug properties in drug discovery
    • Li A.P. Screening for human ADME/Tox drug properties in drug discovery. Drug Discov. Today. 6:2001;357-366.
    • (2001) Drug Discov. Today , vol.6 , pp. 357-366
    • Li, A.P.1
  • 6
    • 0027433317 scopus 로고
    • Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs
    • Jin C., Miners J.O., Lillywhite K.J., Mackenzie P.I. Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs. J. Pharmacol. Exp. Ther. 264:1993;475-479.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 475-479
    • Jin, C.1    Miners, J.O.2    Lillywhite, K.J.3    Mackenzie, P.I.4
  • 8
    • 0035149349 scopus 로고    scopus 로고
    • Use of cloned and expressed human UDP-glucuronosyltransferases for the assessment of human drug conjugation and identification of potential drug interactions
    • Ethell B.T., Beaumont K., Rance D.J., Burchell B. Use of cloned and expressed human UDP-glucuronosyltransferases for the assessment of human drug conjugation and identification of potential drug interactions. Drug Metab. Dispos. 29:2001;48-53.
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 48-53
    • Ethell, B.T.1    Beaumont, K.2    Rance, D.J.3    Burchell, B.4
  • 9
    • 0035154231 scopus 로고    scopus 로고
    • Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney
    • Soars M.G., Riley R.J., Findlay K.A.B., Coffey M.J., Burchell B. Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney. Drug Metab. Dispos. 29:2001;121-126.
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 121-126
    • Soars, M.G.1    Riley, R.J.2    Findlay, K.A.B.3    Coffey, M.J.4    Burchell, B.5
  • 10
    • 0035692560 scopus 로고    scopus 로고
    • Evaluation of the marmoset as a model species for drug glucuronidation
    • Soars M.G., Riley R.J., Burchell B. Evaluation of the marmoset as a model species for drug glucuronidation. Xenobiotica. 31:2001;849-860.
    • (2001) Xenobiotica , vol.31 , pp. 849-860
    • Soars, M.G.1    Riley, R.J.2    Burchell, B.3
  • 11
    • 0035878947 scopus 로고    scopus 로고
    • Cloning and characterization of a canine UDP-glucuronosyltransferase
    • Soars M.G., Smith D.J., Riley R., Burchell B. Cloning and characterization of a canine UDP-glucuronosyltransferase. Arch. Biochem. Biophys. 391:2001;218-224.
    • (2001) Arch. Biochem. Biophys. , vol.391 , pp. 218-224
    • Soars, M.G.1    Smith, D.J.2    Riley, R.3    Burchell, B.4
  • 12
    • 0021381028 scopus 로고
    • A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
    • addendum to Vol. 132, p. 6-13, 1983
    • Feinberg AP, Vogelstein B. "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity" (addendum to Vol. 132, p. 6-13, 1983). Anal Biochem 1984;137:266-7.
    • (1984) Anal Biochem , vol.137 , pp. 266-267
    • Feinberg, A.P.1    Vogelstein, B.2
  • 13
    • 0023254046 scopus 로고
    • Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme
    • Coughtrie M.W.H., Burchell B., Shepherd I.M., Bend J.R. Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme. Mol. Pharmacol. 31:1987;585-591.
    • (1987) Mol. Pharmacol , vol.31 , pp. 585-591
    • Coughtrie, M.W.H.1    Burchell, B.2    Shepherd, I.M.3    Bend, J.R.4
  • 15
    • 0031974584 scopus 로고    scopus 로고
    • A universal radiochemical high performance liquid chromatographic assay for the determination of UDP-glucuronosyltransferase activity
    • Ethell B.T., Anderson G., Beaumont K., Rance D.J., Burchell B. A universal radiochemical high performance liquid chromatographic assay for the determination of UDP-glucuronosyltransferase activity. Anal. Biochem. 225:1998;142-147.
    • (1998) Anal. Biochem. , vol.225 , pp. 142-147
    • Ethell, B.T.1    Anderson, G.2    Beaumont, K.3    Rance, D.J.4    Burchell, B.5
  • 16
    • 0028044817 scopus 로고
    • A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids
    • Pritchard M., Fournel-Gigleux S., Siest G., Mackenzie P., Magdalou J. A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids. Mol. Pharmacol. 45:1994;42-50.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 42-50
    • Pritchard, M.1    Fournel-Gigleux, S.2    Siest, G.3    Mackenzie, P.4    Magdalou, J.5
  • 17
    • 0031034450 scopus 로고    scopus 로고
    • Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds
    • King C.D., Rios G.R., Green M.D., Mackenzie P.I., Tephly T.R. Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds. Drug. Metab. Dispos. 25:1997;251-255.
    • (1997) Drug. Metab. Dispos. , vol.25 , pp. 251-255
    • King, C.D.1    Rios, G.R.2    Green, M.D.3    Mackenzie, P.I.4    Tephly, T.R.5
  • 18
    • 0344193606 scopus 로고    scopus 로고
    • Glucuronidation of opioids, carboxylic acid-containing drugs, and hydroxylated xenobiotics catalyzed by expressed monkey UDP-glucuronosyltransferase 2B9 protein
    • Green M.D., Belanger G., Hum D.W., Belanger A., Tephly T. Glucuronidation of opioids, carboxylic acid-containing drugs, and hydroxylated xenobiotics catalyzed by expressed monkey UDP-glucuronosyltransferase 2B9 protein. Drug. Metab. Dispos. 25:1997;1389-1394.
    • (1997) Drug. Metab. Dispos. , vol.25 , pp. 1389-1394
    • Green, M.D.1    Belanger, G.2    Hum, D.W.3    Belanger, A.4    Tephly, T.5
  • 19
    • 0031894377 scopus 로고    scopus 로고
    • The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268)
    • Coffman B.L., King C.D., Rios G.R., Tephly T.R. The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268). Drug Metab. Dispos. 26:1998;73-77.
    • (1998) Drug Metab. Dispos. , vol.26 , pp. 73-77
    • Coffman, B.L.1    King, C.D.2    Rios, G.R.3    Tephly, T.R.4
  • 20
    • 0034081480 scopus 로고    scopus 로고
    • The glucuronidation of morphine by dog liver microsomes: Identification of morphine-6-O-glucuronide
    • King C., Finley B., Franklin R. The glucuronidation of morphine by dog liver microsomes: identification of morphine-6-O-glucuronide. Drug. Metab. Dispos. 28:2000;661-663.
    • (2000) Drug. Metab. Dispos. , vol.28 , pp. 661-663
    • King, C.1    Finley, B.2    Franklin, R.3
  • 21
    • 0025032241 scopus 로고
    • Species differences in metabolism of codeine: Urinary excretion of codeine glucuronide morphine-3-glucuronidem, and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits
    • Oguri K., Hanioka N., Yoshimura H. Species differences in metabolism of codeine: urinary excretion of codeine glucuronide morphine-3-glucuronidem, and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits. Xenobiotica. 20:1990;683-688.
    • (1990) Xenobiotica , vol.20 , pp. 683-688
    • Oguri, K.1    Hanioka, N.2    Yoshimura, H.3
  • 23
    • 0024424765 scopus 로고
    • The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme
    • Coughtrie M.W.H., Ask B., Rane A., Burchell B., Hume R. The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme. Biochem. Pharmacol. 38:1989;3273-3280.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3273-3280
    • Coughtrie, M.W.H.1    Ask, B.2    Rane, A.3    Burchell, B.4    Hume, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.