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Volumn 53, Issue 2, 2004, Pages 229-234

Evidence for the presence of functional protease activated receptor 4 (PAR4) in the rat colon

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; ARGINYLTYROSYLPROLYLGLYCYLLYSYLGLYCINAMIDE; ATROPINE; CAPSAICIN; GLYCYLTYROSYLPROLYLGLYCYLLYSYLPHENYLALANINAMIDE; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 2 RECEPTOR ANTAGONIST; NOLPITANTIUM; PEPTIDE DERIVATIVE; PROTEINASE ACTIVATED RECEPTOR 4; SAREDUTANT; TETRODOTOXIN; UNCLASSIFIED DRUG;

EID: 1642574390     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2003.021899     Document Type: Article
Times cited : (53)

References (41)
  • 1
    • 0031744875 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
    • Dery O, Corvera CU, Steinhoff M, et al. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol 1998;274:C1429-52.
    • (1998) Am J Physiol , vol.274
    • Dery, O.1    Corvera, C.U.2    Steinhoff, M.3
  • 3
    • 0034629468 scopus 로고    scopus 로고
    • Cathepsin G activates protease-activated receptor-4 in human platelets
    • Sambrano GR, Huang W, Faruqi T, et al. Cathepsin G activates protease-activated receptor-4 in human platelets. J Biol Chem 2000;275:6818-23.
    • (2000) J Biol Chem , vol.275 , pp. 6818-6823
    • Sambrano, G.R.1    Huang, W.2    Faruqi, T.3
  • 4
    • 0034055571 scopus 로고    scopus 로고
    • Proteinase-activated receptors - Novel signals for gastrointestinal pathophysiology
    • Vergnolle N. Proteinase-activated receptors - novel signals for gastrointestinal pathophysiology. Aliment Pharmacol Ther 2000;14:257-66.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 257-266
    • Vergnolle, N.1
  • 5
    • 0032896792 scopus 로고    scopus 로고
    • Trypsin activates pancreatic duct epithelial cell ion channels
    • Nguyen TD, Moody MW, Steinhoff M, et al. Trypsin activates pancreatic duct epithelial cell ion channels. J Clin Invest 1999;103:261-9.
    • (1999) J Clin Invest , vol.103 , pp. 261-269
    • Nguyen, T.D.1    Moody, M.W.2    Steinhoff, M.3
  • 6
    • 0033997882 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2 (PAR-2): Regulation of salivary and pancreatic exocrine secretion in vivo in rats and mice
    • Kawabata A, Nishikawa H, Kuroda R, et al. Proteinase-activated receptor-2 (PAR-2): regulation of salivary and pancreatic exocrine secretion in vivo in rats and mice. Br J Pharmacol 2000;129:1808-14.
    • (2000) Br J Pharmacol , vol.129 , pp. 1808-1814
    • Kawabata, A.1    Nishikawa, H.2    Kuroda, R.3
  • 8
    • 0034872420 scopus 로고    scopus 로고
    • In vivo evidence that protease-activated receptors 1 and 2 modulate gastrointestinal transit in the mouse
    • Kawabata A, Kuroda R, Nagata N, et al. In vivo evidence that protease-activated receptors 1 and 2 modulate gastrointestinal transit in the mouse. Br J Pharmacol 2001;133:1213-18.
    • (2001) Br J Pharmacol , vol.133 , pp. 1213-1218
    • Kawabata, A.1    Kuroda, R.2    Nagata, N.3
  • 9
    • 0028825940 scopus 로고
    • Detection of functional receptors for the proteinase-activated-receptor- 2-activating palypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle
    • Al-Ani B, Saifeddine M, Hollenberg MD. Detection of functional receptors for the proteinase-activated-receptor-2-activating palypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle. Can J Physiol Pharmacol 1995;73:1203-7.
    • (1995) Can J Physiol Pharmacol , vol.73 , pp. 1203-1207
    • Al-Ani, B.1    Saifeddine, M.2    Hollenberg, M.D.3
  • 10
    • 0030008482 scopus 로고    scopus 로고
    • Rat prateinase-activated receptor-2 (PAR-2): cDNA sequence and activity of receptor-derived peptides in gastric and vascular tissue
    • Saifeddine M, Al-Ani B, Cheng CH, et al. Rat prateinase-activated receptor-2 (PAR-2): cDNA sequence and activity of receptor-derived peptides in gastric and vascular tissue. Br J Pharmacol 1996;118:521-30.
    • (1996) Br J Pharmacol , vol.118 , pp. 521-530
    • Saifeddine, M.1    Al-Ani, B.2    Cheng, C.H.3
  • 11
    • 1842414265 scopus 로고    scopus 로고
    • Most cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2
    • Corvera CU, Déry O, Mccanalague K, et al. Most cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2. J Clin Invest 1997;100:1383-93.
    • (1997) J Clin Invest , vol.100 , pp. 1383-1393
    • Corvera, C.U.1    Déry, O.2    Mccanalague, K.3
  • 13
    • 0030823980 scopus 로고    scopus 로고
    • Proteinase activated receptor: Structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides
    • Hollenberg MD, Saifeddine M, Al-Ani B, et al. Proteinase activated receptor: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides. Can J Physiol Pharmacol 1997;75:832-41.
    • (1997) Can J Physiol Pharmacol , vol.75 , pp. 832-841
    • Hollenberg, M.D.1    Saifeddine, M.2    Al-Ani, B.3
  • 14
    • 0031978961 scopus 로고    scopus 로고
    • Parallel contractile signal transduction pathways activated by receptors for thrombin and epidermal growth factor-urogastrone in guinea pig gastric smooth muscle: Blockade by inhibitors of mitogen-activated protein kinase-kinase and phosphatidyl inositol 3′-kinase
    • Zheng XL, Renaux B, Hollenberg MD. Parallel contractile signal transduction pathways activated by receptors for thrombin and epidermal growth factor-urogastrone in guinea pig gastric smooth muscle: blockade by inhibitors of mitogen-activated protein kinase-kinase and phosphatidyl inositol 3′-kinase. J Pharmacol Exp Ther 1998;285:325-34.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 325-334
    • Zheng, X.L.1    Renaux, B.2    Hollenberg, M.D.3
  • 15
    • 0032971765 scopus 로고    scopus 로고
    • Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle
    • Cocks TM, Sozzi V, Moffatt JD, et al. Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle. Gastroenterology 1999;116:586-92.
    • (1999) Gastroenterology , vol.116 , pp. 586-592
    • Cocks, T.M.1    Sozzi, V.2    Moffatt, J.D.3
  • 16
    • 0032695476 scopus 로고    scopus 로고
    • Modulation by protease-activated receptors of the rat duodenal motility in vitro: Possible mechanisms underlying the evoked contraction and relaxation
    • Kawabata A, Kuroda R, Nishikawa H, et al. Modulation by protease-activated receptors of the rat duodenal motility in vitro: possible mechanisms underlying the evoked contraction and relaxation. Br J Pharmacol 1999;128:865-72.
    • (1999) Br J Pharmacol , vol.128 , pp. 865-872
    • Kawabata, A.1    Kuroda, R.2    Nishikawa, H.3
  • 17
    • 0034613016 scopus 로고    scopus 로고
    • Characterization of protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle
    • Kawabata A, Kuroda R, Kuroki N, et al. Characterization of protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle. Life Sci 2000;67:2521-30.
    • (2000) Life Sci , vol.67 , pp. 2521-2530
    • Kawabata, A.1    Kuroda, R.2    Kuroki, N.3
  • 18
    • 0035223826 scopus 로고    scopus 로고
    • Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder
    • Tognetto M, Trevisani M, Maggiore B, et al. Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br J Pharmacol 2000;131:689-94.
    • (2000) Br J Pharmacol , vol.131 , pp. 689-694
    • Tognetto, M.1    Trevisani, M.2    Maggiore, B.3
  • 19
    • 0036016106 scopus 로고    scopus 로고
    • Dual effect mediated by protease-activated receptors on the mechanical activity of rat colon
    • Mulè F, Baffi MC, Cerra MC. Dual effect mediated by protease-activated receptors on the mechanical activity of rat colon. Br J Pharmacol 2002;136:367-74.
    • (2002) Br J Pharmacol , vol.136 , pp. 367-374
    • Mulè, F.1    Baffi, M.C.2    Cerra, M.C.3
  • 20
    • 0036896113 scopus 로고    scopus 로고
    • Signal transduction pathways involved in the mechanical responses to the protease-activated receptors in rat colon
    • Mulè F, Baffi MC, Falzone M, et al. Signal transduction pathways involved in the mechanical responses to the protease-activated receptors in rat colon. J Pharmacol Exp Ther 2002;303:1-8.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 1-8
    • Mulè, F.1    Baffi, M.C.2    Falzone, M.3
  • 21
    • 0032499696 scopus 로고    scopus 로고
    • Cloning and characterization of human protease-activated receptor 4
    • Xu WF, Andersen H, Whitmore TE, et al. Cloning and characterization of human protease-activated receptor 4. Proc Nat Acad Sci U S A 1998;95:6642-6.
    • (1998) Proc Nat Acad Sci U S A , vol.95 , pp. 6642-6646
    • Xu, W.F.1    Andersen, H.2    Whitmore, T.E.3
  • 22
    • 0033771536 scopus 로고    scopus 로고
    • Dual modulation by thrombin of the motility of rat oesophageal muscularis mucosae via two distinct protease-activated receptors (PARs): A novel role for PAR-4 as opposed to PAR-1
    • Kawabata A, Kuroda R, Kuroki N, et al. Dual modulation by thrombin of the motility of rat oesophageal muscularis mucosae via two distinct protease-activated receptors (PARs): a novel role for PAR-4 as opposed to PAR-1. Br J Pharmacol 2000;131:578-84.
    • (2000) Br J Pharmacol , vol.131 , pp. 578-584
    • Kawabata, A.1    Kuroda, R.2    Kuroki, N.3
  • 23
    • 0034528452 scopus 로고    scopus 로고
    • Effect of protease-activated receptor (PAR)-1, -2 and -4-activating peptides, thrombin and trypsin in rat isolated airways
    • Chow JM, Moffatt JD, Cocks TM. Effect of protease-activated receptor (PAR)-1, -2 and -4-activating peptides, thrombin and trypsin in rat isolated airways. Br J Pharmacol 2000;131:1584-91.
    • (2000) Br J Pharmacol , vol.131 , pp. 1584-1591
    • Chow, J.M.1    Moffatt, J.D.2    Cocks, T.M.3
  • 24
    • 0006296520 scopus 로고    scopus 로고
    • Modulation of airway smooth muscle tone by protease activated receptor-1, -2, -3 and -4 in trachea isolated from influenza a virus-infected mice
    • Lan RS, Stewart GA, Henry PJ. Modulation of airway smooth muscle tone by protease activated receptor-1, -2, -3 and -4 in trachea isolated from influenza A virus-infected mice. Br J Pharmacol 2000;129:63-70.
    • (2000) Br J Pharmacol , vol.129 , pp. 63-70
    • Lan, R.S.1    Stewart, G.A.2    Henry, P.J.3
  • 25
    • 0034733558 scopus 로고    scopus 로고
    • Structure-function analysis of protease-activated receptor 4 tethered ligand peptides
    • Faruqi TR, Weiss EJ, Shapiro MJ, et al. Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. J Biol Chem 2000;275:19728-34.
    • (2000) J Biol Chem , vol.275 , pp. 19728-19734
    • Faruqi, T.R.1    Weiss, E.J.2    Shapiro, M.J.3
  • 26
    • 0028816358 scopus 로고
    • Tachykinins and calcitonin gene-related peptide (CGRP) as cotransmitters released from peripheral endings of sensory nerves
    • Maggi CA. Tachykinins and calcitonin gene-related peptide (CGRP) as cotransmitters released from peripheral endings of sensory nerves. Prog Neurobiol 1995;45:1-98.
    • (1995) Prog Neurobiol , vol.45 , pp. 1-98
    • Maggi, C.A.1
  • 27
    • 0025871477 scopus 로고
    • Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons
    • Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 1991;43:143-201.
    • (1991) Pharmacol Rev , vol.43 , pp. 143-201
    • Holzer, P.1
  • 28
    • 0033623157 scopus 로고    scopus 로고
    • 2 receptors in the modulation of spontaneous motility in rat proximal colon
    • 2 receptors in the modulation of spontaneous motility in rat proximal colon. Neurogastroenterol Mot 2000;12:459-66.
    • (2000) Neurogastroenterol Mot , vol.12 , pp. 459-466
    • Mulè, F.1    D'Angelo, S.2    Tabacchi, G.3
  • 29
    • 0038002035 scopus 로고    scopus 로고
    • Involvement of nitric oxide and tachykinins in the effects induced by protease-activated receptors in rat colon longitudinal muscle
    • Mulè F, Baffi MC, Capparelli A, et al. Involvement of nitric oxide and tachykinins in the effects induced by protease-activated receptors in rat colon longitudinal muscle. Br J Pharmacol 2003;139:598-604.
    • (2003) Br J Pharmacol , vol.139 , pp. 598-604
    • Mulè, F.1    Baffi, M.C.2    Capparelli, A.3
  • 30
    • 0032514474 scopus 로고    scopus 로고
    • A dual thrombin receptor system for platelet activation
    • Kahn ML, Zheng YW, Huang W, et al. A dual thrombin receptor system for platelet activation. Nature 1998;394:690-4.
    • (1998) Nature , vol.394 , pp. 690-694
    • Kahn, M.L.1    Zheng, Y.W.2    Huang, W.3
  • 31
    • 0033559805 scopus 로고    scopus 로고
    • Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
    • Kahn ML, Nakanishi-Matsui M, Shapiro MJ, et al. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 1999;103:879-87.
    • (1999) J Clin Invest , vol.103 , pp. 879-887
    • Kahn, M.L.1    Nakanishi-Matsui, M.2    Shapiro, M.J.3
  • 32
    • 0035066614 scopus 로고    scopus 로고
    • Evidence for functionally active protease-activated receptor-4 (PAR-4) in human vascular smooth muscle cells
    • Bretschneider E, Kaufmann R, Braun M, et al. Evidence for functionally active protease-activated receptor-4 (PAR-4) in human vascular smooth muscle cells. Br J Pharmacol 2000;132:1441-6.
    • (2000) Br J Pharmacol , vol.132 , pp. 1441-1446
    • Bretschneider, E.1    Kaufmann, R.2    Braun, M.3
  • 33
    • 0032748545 scopus 로고    scopus 로고
    • Protease-ativated receptors and platelet function
    • Coughlin SR. Protease-ativated receptors and platelet function. Thomb Haemost 1999;82:353-6.
    • (1999) Thomb Haemost , vol.82 , pp. 353-356
    • Coughlin, S.R.1
  • 34
    • 0345004978 scopus 로고    scopus 로고
    • Thrambin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2
    • Corvera CU, Déry O, Mcconalogue K, et al. Thrambin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2. J Physiol 1999;517:741-56.
    • (1999) J Physiol , vol.517 , pp. 741-756
    • Corvera, C.U.1    Déry, O.2    Mcconalogue, K.3
  • 35
    • 0033798625 scopus 로고    scopus 로고
    • Intestinal type 2 proteinase-activated receptors: Expression in opioid-sensitive secretomotor neural circuits that mediate epithelial ion transport
    • Green BT, Bunnett NW, Kulkarni-Narla A, et al. Intestinal type 2 proteinase-activated receptors: expression in opioid-sensitive secretomotor neural circuits that mediate epithelial ion transport. J Pharmacol Exp Therap 2000;295:410-16.
    • (2000) J Pharmacol Exp Therap , vol.295 , pp. 410-416
    • Green, B.T.1    Bunnett, N.W.2    Kulkarni-Narla, A.3
  • 36
    • 0345074090 scopus 로고    scopus 로고
    • Expression of protease-activated receptor-1, -2, -3, and -4 in control and experimentally inflamed mouse bladder
    • D'Andrea MR, Saban MR, Nguyen NB, et al. Expression of protease-activated receptor-1, -2, -3, and -4 in control and experimentally inflamed mouse bladder. Am J Pathol 2003;162:907-23.
    • (2003) Am J Pathol , vol.162 , pp. 907-923
    • D'Andrea, M.R.1    Saban, M.R.2    Nguyen, N.B.3
  • 37
    • 10244242550 scopus 로고    scopus 로고
    • Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract
    • Grady EF, Baluk P, Böhm S, et al. Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract. J Neurosci 1996;16:6975-86.
    • (1996) J Neurosci , vol.16 , pp. 6975-6986
    • Grady, E.F.1    Baluk, P.2    Böhm, S.3
  • 38
    • 0032470054 scopus 로고    scopus 로고
    • Tachykinins mediate noncholinergic excitatory neural responses in the circular muscle of rat proximal colon
    • Serio R, Mulè F, Bonvissuto F, et al. Tachykinins mediate noncholinergic excitatory neural responses in the circular muscle of rat proximal colon. Can J Physiol Pharmacol 1998;76:684-9.
    • (1998) Can J Physiol Pharmacol , vol.76 , pp. 684-689
    • Serio, R.1    Mulè, F.2    Bonvissuto, F.3
  • 39
    • 0033971235 scopus 로고    scopus 로고
    • Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
    • Steinhoff M, Vergnolle N, Yaung SH, et al. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nat Med 2000;6:151-8.
    • (2000) Nat Med , vol.6 , pp. 151-158
    • Steinhoff, M.1    Vergnolle, N.2    Yaung, S.H.3
  • 40
    • 0033694764 scopus 로고    scopus 로고
    • Trypsin-induced, neurokinin-mediated contraction of guinea-pig bronchus
    • Carr MJ, Schechter M, Undem BJ. Trypsin-induced, neurokinin-mediated contraction of guinea-pig bronchus. Am J Resp Crit Care Med 2000;162:1662-7.
    • (2000) Am J Resp Crit Care Med , vol.162 , pp. 1662-1667
    • Carr, M.J.1    Schechter, M.2    Undem, B.J.3
  • 41
    • 0034027359 scopus 로고    scopus 로고
    • Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways
    • Ricciardolo FL, Steinhoff M, Amadesi S, et al. Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways. Am J Resp Crit Care Med 2000;161:1672-80.
    • (2000) Am J Resp Crit Care Med , vol.161 , pp. 1672-1680
    • Ricciardolo, F.L.1    Steinhoff, M.2    Amadesi, S.3


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