Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle

Gastroenterology

Volumn 116, Issue 3, 1999, Pages 586-592

  Cocks, T M ^a   Sozzi, V ^a   Moffatt, J D ^a   Selemidis, S ^a  

^a Tri radiate Building   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

APAMIN; CELL RECEPTOR; NIFEDIPINE; RYANODINE;

ANIMAL TISSUE; ARTICLE; COLON TENIA; CONTROLLED STUDY; FEMALE; GUINEA PIG; INTESTINE CONTRACTION; INTESTINE MUSCLE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; STOMACH FUNDUS; STOMACH MUSCLE;

EID: 0032971765     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70180-0     Document Type: Article

References (33)

1. SR. Coughlin Protease-activated receptors start a family Proc Natl Acad Sci USA 91 1994 9200 9202
2. TK Vu DT Hung VI Wheaton SR. Coughlin Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation Cell 64 1991 1057 1068
3. S Nystedt K Emilsson C Wahlestedt J. Sundelin Molecular cloning of a potential proteinase activated receptor Proc Natl Acad Sci USA 91 1994 9208 9212
4. H Ishihara AJ Connolly D Zeng ML Kahn YW Zheng C Timmons T Tram SR. Coughlin Protease-activated receptor 3 is a second thrombin receptor in humans Nature 386 1997 502 506
5. M Molino ES Barnathan R Numerof J Clark M Dreyer A Cumashi JA Hoxie N Schecter M Woolkalis LF. Brass Interactions of mast cell tryptase with thrombin receptors and PAR-2 J Biol Chem 272 1997 4043 4049
6. WF Xu H Andersen TE Whitmore SR Presnell DP Yee A Ching T Gilbert EW Davie DC. Foster Cloning and characterization of human protease-activated receptor 4 Proc Natl Acad Sci USA 95 1998 6642 6646
7. M Saifeddine B Al-Ani CH Cheng L Wang MD. Hollenberg Rat proteinase-activated receptor-2 (PAR-2): cDNA sequence and activity of receptor-derived peptides in gastric and vascular tissue Br J Pharmacol 118 1996 521 530
8. SK Bohm W Kong D Bromme SP Smeekens DC Anderson A Connolly M Kahn NA Nelken SR Couglin DG Payan NW. Bunnett Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2 Biochem J 314 1996 1009 1016
9. W Kong K McConalogue LM Khitin MD Hollenberg DG Payan SK Bohm NW. Bunnett Luminal trypsin may regulate enterocytes through proteinase-activated receptor-2 Proc Natl Acad Sci USA 94 1997 8884 8889
10. T Hartmann SJ Ruoss GH. Caughey Modulation of thrombin and thrombin receptor peptide mitogenicity by human lung mast cell tryptase Am J Physiol 267 1994 L113 L119
11. H Mirza V Yatsula WF. Bahou The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells J Clin Invest 97 1996 1705 1714
12. G. Fager Thrombin and proliferation of vascular smooth muscle cells Circ Res 77 1995 645 650
13. CU Corvera O Dery K McConalogue SK Bohm LM Khitin GH Caughey DG Payan NW. Bunnett Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2 J Clin Invest 100 1997 1383 1393
14. MD Hollenberg M Saifeddine AA Bahjat A. Kawabata Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides Can J Physiol Pharmacol 75 1997 832 841
15. BD Blackhart K Emilsson D Nguyen W Teng AJ Martelli S Nystedt J Sundelin RM. Scarborough Ligand cross-reactivity within the protease-activated receptor family J Biol Chem 271 1996 16466 16471
16. 2+ channels Br J Pharmacol 117 1996 1035 1040
17. B Al-Ani M Saifeddine MD. Hollenberg Detection of functional receptors for the proteinase-activated receptor 2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle Can J Physiol Pharmacol 73 1995 1203 1207
18. AA Laniyonu MD. Hollenberg Vascular actions of thrombin receptor-derived polypetides: structure-activity profiles for contractile and relaxant effects in rat aorta Br J Pharmacol 114 1995 1680 1686
19. S Selemidis DG Satchell TM. Cocks Evidence that NO acts as a redundant NANC inhibitory neurotransmitter in the guinea-pig isolated taenia coli Br J Pharmacol 121 1997 604 611
20. 2+-release channels Trends Pharmacol Sci 15 1994 145 149
21. MT Nelson H Cheng M Rubart LF Santana AD Bonev HJ Knot WJ. Lederer Relaxation of arterial smooth muscle by calcium sparks Science 270 1995 633 637
22. 2+-dependent ion channels in single myocytes from rat portal vein Cell Calcium 20 1996 153 160
23. − conductance in smooth muscle Am J Physiol 271 1996 C435 C454
24. M Schultheiss B Neumake HP. Richter Endogenous trypsin receptor in Xenopus oocytes—linkage to internal calcium stores Cell Mol Life Sci 53 1997 842 849
25. P Pacaud G Loirand JL Lavie C Mironneau J. Mironneau Calcium-activated chloride current in rat vascular smooth muscle cells in short-term primary culture Pflugers Arch 413 1989 629 636
26. LW Brass DR Manning AG Williams MJ Woolkalis M. Poncz Receptor and G-protein-mediated responses to thrombin in HEL cells J Biol Chem 266 1991 958 965
27. S Verrall M Ishii M Chen L Wang T Tram SR. Coughlin The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors J Biol Chem 272 1997 6898 6902
28. M Molino MJ Woolkalis J Reavey-Cantwell D Pratico P Andrade-Gordon ES Barnathan LF. Brass Endothelial cell thrombin receptors and PAR-2: two protease-activated receptors located in a single cellular environment J Biol Chem 272 1997 11133 11141
29. A Den Hertog A Nelemans JVD. Akker The inhibitory action of suramin on the P2-purinoceptor response in smooth muscle cells of guinea-pig taenia caeci Eur J Pharmacol 166 1989 531 534
30. MF Shuba IA. Vladimirova Effect of apamin on the electrical responses of smooth muscle to adenosine 5'-triphosphate and to non-adrenergic, non-cholinergic nerve stimulation Neuroscience 5 1980 853 859
31. JD Ferrero TM Cocks G. Burnstock A comparison between ATP and bradykinin as possible mediators of the responses of smooth muscle to non-adrenergic, non-cholinergic nerves Eur J Pharmacol 63 1980 295 302
32. K McConalogue DJK Lyster JB. Furness Electrophysiological analysis of the actions of pituitary adenylyl cyclase activating peptide in the taenia of the guinea-pig caecum Naunyn Schmiedebergs Arch Pharmacol 352 1995 538 544
33. MA. Bennett Non-adrenergic non-cholinergic (NANC) transmission to smooth muscle: 35 years on Prog Neurobiol 52 1997 159 195