The region of antithrombin interacting with full-length heparin chains outside the high-affinity pentasaccharide sequence extends to LYS136 but not to Lys139

Biochemistry

Volumn 39, Issue 29, 2000, Pages 8512-8518

  Arocas, Véronique ^a,d   Turk, Boris ^a,e   Bock, Susan C ^b   Olson, Steven T ^c   Björk, Ingemar ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 10A; HEPARIN; LYSINE; PENTASACCHARIDE;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DISSOCIATION CONSTANT; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ANTITHROMBINS; BINDING SITES; FACTOR XA; HEPARIN; HUMANS; KINETICS; LYSINE; OLIGOSACCHARIDES; POINT MUTATION; RECOMBINANT PROTEINS; VARIATION (GENETICS);

EID: 0034713836     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9928243     Document Type: Article

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