Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites

Biochemistry

Volumn 42, Issue 27, 2003, Pages 8143-8152

  Bedsted, Tina ^a   Swanson, Richard ^a   Chuang, Yung Jen ^a,d   Bock, Paul E ^b   Björk, Ingemar ^c   Olson, Steven T ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CALCIUM; COAGULATION; SUBSTRATES;

ALLOSTERIC ACTIVATION;

BIOCHEMISTRY;

ANTITHROMBIN; BLOOD CLOTTING FACTOR 9A; CALCIUM ION; HEPARIN;

ALLOSTERISM; ARTICLE; FAST PROTEIN LIQUID CHROMATOGRAPHY; HYDROLYSIS; MUTAGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANTITHROMBINS; CALCIUM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FACTOR IXA; HEPARIN; KINETICS; OLIGOSACCHARIDES;

EID: 0038164797     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034363y     Document Type: Article

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