Antioxidative treatment reverses imbalances of nitric oxide synthase isoform expression and attenuates tissue-cGMP activation in diabetic rats

Biochemical and Biophysical Research Communications

Volumn 316, Issue 3, 2004, Pages 771-780

  Bojunga, Jörg ^a   Dresar Mayert, Birgit ^b   Usadel, Klaus Henning ^b   Kusterer, Klaus ^b   Zeuzem, Stefan ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Lipoicacid; Ascorbicacid; cGMP; Diabetes; Immunohistochemistry; Nitric oxide; Oxidative stress; Plasma thiols; RT PCR; Streptozotocin

Indexed keywords

ANTIOXIDANT; CYCLIC GMP; GLUCOSE; ISOENZYME; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; THIOCTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; CONTROLLED STUDY; DATA ANALYSIS; DIABETES MELLITUS; DOWN REGULATION; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME DEGRADATION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RNA ANALYSIS; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BLOOD GLUCOSE; CYCLIC GMP; DIABETES MELLITUS, EXPERIMENTAL; DNA PRIMERS; DOWN-REGULATION; IMMUNOHISTOCHEMISTRY; MALE; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; NITRITES; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFHYDRYL COMPOUNDS; THIOCTIC ACID; TISSUE DISTRIBUTION; UP-REGULATION;

EID: 1642272136     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.02.110     Document Type: Article

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