Enhanced, unaltered and impaired nitric oxide-mediated endothelium- dependent relaxation in experimental diabetes mellitus: Importance of disease duration

Diabetologia

Volumn 42, Issue 2, 1999, Pages 204-213

  Pieper, G M ^a,b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b FROEDTERT MEMORIAL LUTHERAN HOSPITAL   (United States)

Author keywords

Diabetes mellitus; Endothelium; Endothelium dependent hyperpolarizing factor; L nitroarginine; Nitric oxide

Indexed keywords

AMINOGUANIDINE; ENDOTHELIUM DERIVED RELAXING FACTOR; NITRIC OXIDE;

ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL FUNCTION; CONTROLLED STUDY; CREMASTER MUSCLE; ENDOTHELIUM CELL; EXPERIMENTAL DIABETES MELLITUS; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE RELAXATION; TISSUE BLOOD FLOW;

ACETYLCHOLINE; ANIMALS; AORTA; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; EPINEPHRINE; INDOMETHACIN; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROARGININE; NITROGLYCERIN; RATS; RATS, SPRAGUE-DAWLEY; TETRAETHYLAMMONIUM; TIME FACTORS; VASODILATOR AGENTS;

EID: 0032950298     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051140     Document Type: Article

References (42)

1. 1. Pieper GM, Gross GJ (1991) Endothelial dysfunction in diabetes. In: Rubanyi GM (ed) Cardiovascular Significance of Endothelium-Derived Vasoactive Factors. Futura Publishing, Mount Kisco, New York, pp 223-249
2. 2. Kamata N, Miyata N, Abiru T, Kasuya Y (1992) Functional changes in vascular smooth muscle and endothelium of arteries during diabetes mellitus. Life Sci 50:1379-1387
3. 3. Cohen RA (1993) Dysfunction of vascular endothelium in diabetes mellitus. Circulation 87 [Suppl V]:V67-V76
4. 4. Poston L, Taylor PD (1995) Endothelium-mediated vascular function in insulin-dependent diabetes mellitus. Clin Sci 88: 245-255
5. 5. Pieper GM (1998) Review of alterations in endothelial nitric oxide production in diabetes. Protective role of arginine on endothelial dysfunction. Hypertension 31: 1047-1060
6. 6. Lash JM, Bohlen HG (1991) Structural and functional origins of suppressed acetylcholine vasodilation in diabetic rat intestinal arterioles. Circ Res 69:1259-1268
7. 7. Kiff RJ, Gardiner SM, Compton AM, Bennett T (1991) Selective impairment of hindquarters vasodilator responses to bradykinin in conscious Wistar rats with streptozotocin-induced diabetes mellitus. Br J Pharmacol 103: 1357-1362
8. 8. Alsip NL, Schuschke DA, Miller FN (1996) Microvascular responses in the skeletal muscle of the diabetic rat. J Lab Clin Med 128: 429-437
9. 9. Diederich D, Skopec J, Diederich A, Dai FX (1994) Endothelial dysfunction in mesenteric arteries of diabetic rat: role of free radicals. Am J Physiol 266 (Heart Circ Physiol 35):H1153-H1161
10. 10. Wang SP, West MW, Dresner LS, Fleishhacker JF, Distant DA, Mueller CM, Wait RB (1996) Effects of diabetes and uremia on mesenteric vascular reactivity. Surgery 120: 328-336
11. 11. Bucala R, Tracey KJ, Cerami A (1991) Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes. J Clin Invest 87: 432-438
12. 12. Orie NN, Aloamaka CP, Iyawe VI (1993) Duration-dependent attenuation of acetylcholine-but not histamine-induced relaxation of the aorta in diabetes mellitus. Gen Pharmacol 24: 329-332
13. 13. Tanz RD, Chang KSK, Weller TS (1989) Histamine relaxation of aortic rings from diabetic rats. Agents Actions 28: 1-8
14. 14. White RE, Carrier GO (1986) Supersensitivity and endothelium dependency of histamine-induced relaxation in mesenteric arteries isolated from diabetic rats. Pharmacology 33: 34-38
15. 15. Bhardwaj R, Moore PK (1988) Increased vasodilator response to acetylcholine of renal blood vessels from diabetic rats. J Pharm Pharmacol 40: 739-742
16. 16. Altan VM, Karasu C, Özüari A (1989) The effects of type-1 and type-2 diabetes on endothelium-dependent relaxation in rat aorta. Pharmacology Biochemistry and Behavior 33: 519-522
17. 17. Wakabayashi I, Hatake K, Kimura N, Kaksishita E, Nagai K (1987) Modulation of vascular tonus by the endothelium in experimental diabetes. Life Sci 40: 643-648
18. 18. Mulhern M, Docherty JR (1989) Effects of experimental diabetes on the responsiveness of rat aorta. Br J Pharmacol 97: 1007-1012
19. 19. Murray P, Pitt B, Webb RC (1994) Ramipril prevents hypersensitivity to phenylephrine in aorta from streptozotocin-induced diabetic rats. Diabetologia 37: 664-670
20. 20. Head RJ, Longhurst PA, Panek RL, Stitzel RE (1987) A contrastine effect of the diabetic state upon contractile responses of aortic preparations from the rat and rabbit. Br J Pharmacol 91: 275-286
21. 21. Graier WF, Wascher TC, Lackner L, Toplak H, Krejs GJ, Kukovetz WF (1993) Exposure to elevated D-glucose concentration modulates vascular endothelial cell vasodilatory responses. Diabetes 42: 1497-1505
22. +) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells. J Physiol (Lond) 490.3: 775-781
23. 23. Pieper GM, Dondlinger LA (1997) Glucose elevations alter bradykinin-stimulated intracellular calcium accumulation in cultured endothleial cells. Cardiovasc Res 34: 169-178
24. 24. Salameh A, Dhein S (1998) Influence of long-term D-glucose exposure and long-term-b-blocker treatment on intracellular calcium concentrations of porcine aortic endothelial cells. Diabetes 47: 407-413
25. 25. Wascher TC, Graier WF, Bahadori B, Toplak H (1994) Time course of endothelial dysfunction in diabetes mellitus. Circulation 90: 1109
26. 26. Anderson T, Schein PS, McMenamin MG, Cooney DA (1974) Streptozotocin diabetes. Correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotide. J Clin Invest 54: 672-677
27. 27. Adolphe AB, Glasofer ED, Troetel WM, Weiss AJ (1977) Preliminary pharmacokinetics of streptozotocin, an antineoplastic antibiotic. J Clin Pharmacol (July):379-388
28. 14C]streptozotocin with special reference to the pancreatic islets. Acta Endocrinologica 89: 339-351
29. 29. Heygate KM, Davies J, Holmes M, James RFL, Thurston H (1996) The effect of insulin treatment and of islet transplantation on the resistance artery function in the STZ-induced diabetic rat. Br J Pharmacol 119: 495-504
30. 30. Kwon NS, Lee SH, Choi CS, Kho T, Lee HS (1994) Nitric oxide generation from streptozotocin. FASEB J 8: 529-533
31. 31. Kröncke K-D, Kolb-Bachofen V (1996) Commentary: streptozotocin is not a spontaneous NO donor. Free Radic Res 24: 77-80
32. 32. Pieper GM (1991) Alterations in reperfusion-stimulated prostacyclin release by the diabetic heart. In: Nagano M, Dhalla NS (eds) The Diabetic Heart. Raven Press, New York, pp 465-483
33. 33. Pieper GM, Langenstroer P, Siebeneich W (1997) Diabeticinduced endothelial dysfunction in rat aorta: role of hydroxyl radicals. Cardiovasc Res 34:145-156
34. 34. Fujii K, Soma M, Huang YS, Manku MS, Horrobin DF (1986) Increased release of prostaglandins from the mesenteric vascular bed in streptoztocotin diabetes. Prog Lipid Res 25: 499-501
35. 35. Pieper GM, Dembny K, Siebeneich, W (1998) Long-term treatment in vivo with NOX-101, a scavenger of nitric oxide, prevents diabetes-induced endothelial dysfunction. Diabetologia 41: 806-812
36. 36. Fukao M, Hattori Y, Kanno M, Sakuma I, Kitabatake A (1997) Alterations in endothelium-dependent hyperpolarization and relaxation in mesenteric arteries from streptozotocin-induced diabetic rats. Br J Pharmacol 121: 1383-1391
37. 37. Endo K, Abiro T, Machida H, Kasuya Y, Kamata, K (1995) Endothelium-derived hyperpolarizing factor does not contribute to the decrease in endothelium-dependent relaxation in the aorta of streptozotocin-induced diabetic rats. Gen Pharmacol 26: 149-153
38. 38. Contreras R, Fuentes O, Mann GE, Sobrevia L (1997) Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands. J Physiol 498: 787-796
39. 39. Myers PR, Wright WF, Tanner MA, Adams HR (1992) EDRF and nitric oxide production in cultured endothelial cells: direct inhibition by E. coli endotoxin. Am J Physiol 262 (Heart Circ Physiol 31): H710-H718
40. 40. Bult H, DeMeyer GRY, Jordaens FH, Herman AG (1991) Long-term exposure to exogenous nitric oxide may suppress its endogenous release and efficacy. J Cardiovasc Pharmacol 17 [Suppl 3]: S79-S82
41. 2+/ EDRF signaling are due to generation of superoxide anions. Diabetes 45: 1386-1395
42. 42. Cosentino F, Hishikawa K, Katusic ZS, Lüscher TF (1997) High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96: 25-28