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Volumn 204, Issue , 2005, Pages 74-86

Pathways to gene identification in rheumatoid arthritis: PTPN22 and beyond

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE N22; T LYMPHOCYTE RECEPTOR; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 16244411098     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2005.00243.x     Document Type: Review
Times cited : (65)

References (53)
  • 1
    • 0033281605 scopus 로고    scopus 로고
    • Genetics of rheumatoid arthritis: Confronting complexity
    • Gregersen PK. Genetics of rheumatoid arthritis: confronting complexity. Arthritis Res 1999;1:37-44.
    • (1999) Arthritis Res , vol.1 , pp. 37-44
    • Gregersen, P.K.1
  • 2
    • 0035012803 scopus 로고    scopus 로고
    • The epidemiology of rheumatoid arthritis
    • Gabriel S. The epidemiology of rheumatoid arthritis. Rheum Dis Clin North Am 2001;27:269-281.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 269-281
    • Gabriel, S.1
  • 3
    • 16244368628 scopus 로고
    • Population prevalence of rheumatoid arthritis is lower than forwerly supposed
    • Ward RH, Hasstedt SJ, Clegg DO. Population prevalence of rheumatoid arthritis is lower than forwerly supposed. Arthritis Rheum 1992;5:S129.
    • (1992) Arthritis Rheum , vol.5
    • Ward, R.H.1    Hasstedt, S.J.2    Clegg, D.O.3
  • 4
    • 0033003164 scopus 로고    scopus 로고
    • The genetics revolution and the assault on rheumatoid arthritis
    • Seldin M, Amos C, Ward R, Gregersen PK. The genetics revolution and the assault on rheumatoid arthritis. Arthritis Rheum 1999;42:1071-1079.
    • (1999) Arthritis Rheum , vol.42 , pp. 1071-1079
    • Seldin, M.1    Amos, C.2    Ward, R.3    Gregersen, P.K.4
  • 5
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse TJ, Todd JA. Genetic analysis of autoimmune disease. Cell 1996;85:311-318.
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 6
    • 0027375302 scopus 로고
    • Twin concordance rates for rheumatoid arthritis: Results from a nationwide study
    • Silman AJ, et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol 1993;32:903-907.
    • (1993) Br J Rheumatol , vol.32 , pp. 903-907
    • Silman, A.J.1
  • 7
    • 0034121235 scopus 로고    scopus 로고
    • Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins
    • MacGregor AJ, et al. Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum 2000;43:30-37.
    • (2000) Arthritis Rheum , vol.43 , pp. 30-37
    • MacGregor, A.J.1
  • 8
    • 0034018518 scopus 로고    scopus 로고
    • The effect of smoking on clinical, laboratory, and radiographic status in rheumatoid arthritis
    • Wolfe F. The effect of smoking on clinical, laboratory, and radiographic status in rheumatoid arthritis. J Rheumatol 2000;27:630-637.
    • (2000) J Rheumatol , vol.27 , pp. 630-637
    • Wolfe, F.1
  • 9
    • 0036184942 scopus 로고    scopus 로고
    • Smoking and disease severity in rheumatoid arthritis: Association with polymorphism at the glutathione S-transferase M1 locus
    • Mattey DL, et al. Smoking and disease severity in rheumatoid arthritis: association with polymorphism at the glutathione S-transferase M1 locus. Arthritis Rheum 2002;46:640-646.
    • (2002) Arthritis Rheum , vol.46 , pp. 640-646
    • Mattey, D.L.1
  • 10
    • 0041823868 scopus 로고    scopus 로고
    • Genetic susceptibility to infectious disease
    • Segal S, Hill AV. Genetic susceptibility to infectious disease. Trends Microbiol 2003;11:445-448.
    • (2003) Trends Microbiol , vol.11 , pp. 445-448
    • Segal, S.1    Hill, A.V.2
  • 11
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995;11:241-247.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 12
    • 0032168750 scopus 로고    scopus 로고
    • New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study
    • Cornelis F, et al. New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci USA 1998;95:10746-10750.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10746-10750
    • Cornelis, F.1
  • 13
    • 0035069106 scopus 로고    scopus 로고
    • A genome-wide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases
    • Jawaheer D, et al. A genome-wide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. Am J Human Genet 2001;68:927-936.
    • (2001) Am J Human Genet , vol.68 , pp. 927-936
    • Jawaheer, D.1
  • 14
    • 0037389679 scopus 로고    scopus 로고
    • Screening the genome for rheumatoid arthritis susceptibility genes: A replication study and combined analysis of 512 multicase families
    • Jawaheer D, et al. Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families. Arthritis Rheum 2003;48:906-916.
    • (2003) Arthritis Rheum , vol.48 , pp. 906-916
    • Jawaheer, D.1
  • 15
    • 0036188754 scopus 로고    scopus 로고
    • Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom
    • MacKay K, et al. Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom. Arthritis Rheum 2002;46:632-639.
    • (2002) Arthritis Rheum , vol.46 , pp. 632-639
    • MacKay, K.1
  • 16
    • 7844245773 scopus 로고    scopus 로고
    • Identification of the gene loci that predispose to rheumatoid arthritis
    • Shiozawa S, et al. Identification of the gene loci that predispose to rheumatoid arthritis. Int Immunol 1998;10:1891-1895.
    • (1998) Int Immunol , vol.10 , pp. 1891-1895
    • Shiozawa, S.1
  • 17
    • 0036185110 scopus 로고    scopus 로고
    • The search for rheumatoid arthritis susceptibility genes: A call for global collaboration
    • Jawaheer D, Gregersen PK. The search for rheumatoid arthritis susceptibility genes: a call for global collaboration. Arthritis Rheum 2002;46:582-584.
    • (2002) Arthritis Rheum , vol.46 , pp. 582-584
    • Jawaheer, D.1    Gregersen, P.K.2
  • 18
    • 3042548992 scopus 로고    scopus 로고
    • Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: Comparison with microsatellites
    • John S, et al. Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites. Am J Hum Genet 2004;75:54-64.
    • (2004) Am J Hum Genet , vol.75 , pp. 54-64
    • John, S.1
  • 19
    • 1842383327 scopus 로고    scopus 로고
    • Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis
    • Hall FC, et al. Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis. Q J Med 1996;89:821-829.
    • (1996) Q J Med , vol.89 , pp. 821-829
    • Hall, F.C.1
  • 20
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • Ueda H, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003;423:506-511.
    • (2003) Nature , vol.423 , pp. 506-511
    • Ueda, H.1
  • 22
    • 0034785352 scopus 로고    scopus 로고
    • Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
    • Rioux JD, et al. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat Genet 2001;29:223-228.
    • (2001) Nat Genet , vol.29 , pp. 223-228
    • Rioux, J.D.1
  • 23
    • 0034795550 scopus 로고    scopus 로고
    • Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex
    • Jeffreys AJ, Kauppi L, Neumann R. Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex. Nat Genet 2001;29:217-222.
    • (2001) Nat Genet , vol.29 , pp. 217-222
    • Jeffreys, A.J.1    Kauppi, L.2    Neumann, R.3
  • 24
    • 0036846152 scopus 로고    scopus 로고
    • Increase in expression of receptor activator of nuclear factor kappaB at sites of bone erosion correlates with progression of inflammation in evolving collagen-induced arthritis
    • Lubberts E, et al. Increase in expression of receptor activator of nuclear factor kappaB at sites of bone erosion correlates with progression of inflammation in evolving collagen-induced arthritis. Arthritis Rheum 2002;46:3055-3064.
    • (2002) Arthritis Rheum , vol.46 , pp. 3055-3064
    • Lubberts, E.1
  • 25
    • 3242713277 scopus 로고    scopus 로고
    • A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • Begovich AB, et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 2004;75:330-337.
    • (2004) Am J Hum Genet , vol.75 , pp. 330-337
    • Begovich, A.B.1
  • 26
    • 2642583283 scopus 로고    scopus 로고
    • Mapping complex disease loci in whole-genome association studies
    • Carlson CS, Eberle MA, Kruglyak L, Nickerson DA. Mapping complex disease loci in whole-genome association studies. Nature 2004;429:446-452.
    • (2004) Nature , vol.429 , pp. 446-452
    • Carlson, C.S.1    Eberle, M.A.2    Kruglyak, L.3    Nickerson, D.A.4
  • 27
    • 0033521596 scopus 로고    scopus 로고
    • Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase
    • Cloutier JF, Veillette A. Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase. J Exp Med 1999;189:111-121.
    • (1999) J Exp Med , vol.189 , pp. 111-121
    • Cloutier, J.F.1    Veillette, A.2
  • 28
    • 0032557659 scopus 로고    scopus 로고
    • Sequence requirements for association of protein-tyrosine phosphatase PEP with the Src homology 3 domain of inhibitory tyrosine protein kinase p50(csk)
    • Gregorieff A, Cloutier JF, Veillette A. Sequence requirements for association of protein-tyrosine phosphatase PEP with the Src homology 3 domain of inhibitory tyrosine protein kinase p50(csk). J Biol Chem 1998;273:13217- 13222.
    • (1998) J Biol Chem , vol.273 , pp. 13217-13222
    • Gregorieff, A.1    Cloutier, J.F.2    Veillette, A.3
  • 29
    • 0942279640 scopus 로고    scopus 로고
    • PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells
    • Hasegawa K, Martin F, Huang G, Tumas D, Dieche L, Chan AC. PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells. Science 2004;303:685-689.
    • (2004) Science , vol.303 , pp. 685-689
    • Hasegawa, K.1    Martin, F.2    Huang, G.3    Tumas, D.4    Dieche, L.5    Chan, A.C.6
  • 30
    • 0034843773 scopus 로고    scopus 로고
    • Ectopic lymphoid organogenesis: A fast track for autoimmunity
    • Weyand CM, Kurtin PJ, Goronzy JJ. Ectopic lymphoid organogenesis: a fast track for autoimmunity. Am J Pathol 2001;159:787-793.
    • (2001) Am J Pathol , vol.159 , pp. 787-793
    • Weyand, C.M.1    Kurtin, P.J.2    Goronzy, J.J.3
  • 32
    • 0032882912 scopus 로고    scopus 로고
    • Rheumatoid factor isotype switch and somatic mutation variants within rheumatoid arthritis synovium
    • Williams DG, Moyes SP, Mageed RA. Rheumatoid factor isotype switch and somatic mutation variants within rheumatoid arthritis synovium. Immunology 1999;98:123-136.
    • (1999) Immunology , vol.98 , pp. 123-136
    • Williams, D.G.1    Moyes, S.P.2    Mageed, R.A.3
  • 33
    • 15944421378 scopus 로고    scopus 로고
    • Autoimmunity
    • St Clair EW, Pisetsky DS, Haynes BF, eds. Philadelphia: Lippincott Williams and Williams
    • Davidson A, Bridges SL Jr. Autoimmunity. In: St Clair EW, Pisetsky DS, Haynes BF, eds. Rheumatoid Arthritis. Philadelphia: Lippincott Williams and Williams, 2004.
    • (2004) Rheumatoid Arthritis
    • Davidson, A.1    Bridges Jr., S.L.2
  • 34
    • 0034111467 scopus 로고    scopus 로고
    • A prospective study on the incidence of rheumatoid arthritis among people with persistent increase of rheumatoid factor
    • Halldorsdottir HD, Jonsson T, Thorsteinsson J, Valdimarsson H. A prospective study on the incidence of rheumatoid arthritis among people with persistent increase of rheumatoid factor. Ann Rheum Dis 2000;59:149-151.
    • (2000) Ann Rheum Dis , vol.59 , pp. 149-151
    • Halldorsdottir, H.D.1    Jonsson, T.2    Thorsteinsson, J.3    Valdimarsson, H.4
  • 35
    • 0032777987 scopus 로고    scopus 로고
    • Regulation of autoreactive anti-IgG (rheumatoid factor) B cells in normal and autoimmune mice
    • Wang H, Schlomchik MJ. Regulation of autoreactive anti-IgG (rheumatoid factor) B cells in normal and autoimmune mice. Immunol Res 1999;19:259-270.
    • (1999) Immunol Res , vol.19 , pp. 259-270
    • Wang, H.1    Schlomchik, M.J.2
  • 38
    • 0032463136 scopus 로고    scopus 로고
    • T cell receptor repertoire in rheumatoid arthritis
    • Goronzy JJ, Zettl A, Weyand CM. T cell receptor repertoire in rheumatoid arthritis. Int Rev Immunol 1998;17:339-363.
    • (1998) Int Rev Immunol , vol.17 , pp. 339-363
    • Goronzy, J.J.1    Zettl, A.2    Weyand, C.M.3
  • 39
    • 0029670731 scopus 로고    scopus 로고
    • + T cell population of rheumatoid arthritis patients
    • + T cell population of rheumatoid arthritis patients. J Immunol 1996;156:852-858.
    • (1996) J Immunol , vol.156 , pp. 852-858
    • Hingorani, R.1
  • 40
    • 0027243784 scopus 로고
    • + T cell expansions in the peripheral blood of rheumatoid arthritis patients
    • + T cell expansions in the peripheral blood of rheumatoid arthritis patients. J Exp Med 1993;177:1623-1631.
    • (1993) J Exp Med , vol.177 , pp. 1623-1631
    • DerSimonian, H.1
  • 42
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
    • Bottini N, et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004;36:337-338.
    • (2004) Nat Genet , vol.36 , pp. 337-338
    • Bottini, N.1
  • 43
    • 4143105691 scopus 로고    scopus 로고
    • Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
    • Kyogoku C, et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet 2004;75:504-507.
    • (2004) Am J Hum Genet , vol.75 , pp. 504-507
    • Kyogoku, C.1
  • 44
    • 0142009533 scopus 로고    scopus 로고
    • Development of autoantibodies before the clinical onset of systemic lupus erythematosus
    • Arbuckle MR, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003;349:1526-1533.
    • (2003) N Engl J Med , vol.349 , pp. 1526-1533
    • Arbuckle, M.R.1
  • 45
    • 1842559613 scopus 로고    scopus 로고
    • GAD65 antibody isotypes and epitope recognition during the prediabetic process in siblings of children with type I diabetes
    • Childhood Diabetes in Finland Study Group
    • Hoppu S, Ronkainen MS, Kulmala P, Akerblom HK, Knip M. Childhood Diabetes in Finland Study Group. GAD65 antibody isotypes and epitope recognition during the prediabetic process in siblings of children with type I diabetes. Clin Exp Immunol 2004;136:120-128.
    • (2004) Clin Exp Immunol , vol.136 , pp. 120-128
    • Hoppu, S.1    Ronkainen, M.S.2    Kulmala, P.3    Akerblom, H.K.4    Knip, M.5
  • 46
    • 0042827414 scopus 로고    scopus 로고
    • Risk factors for and prevalence of thyroid disorders in a cross-sectional study among healthy female relatives of patients with autoimmune thyroid disease
    • Strieder TG, Prummel MF, Tijssen JG, Endert E, Wiersinga WM. Risk factors for and prevalence of thyroid disorders in a cross-sectional study among healthy female relatives of patients with autoimmune thyroid disease. Clin Endocrinol (Oxf) 2003;59:396-401.
    • (2003) Clin Endocrinol (Oxf) , vol.59 , pp. 396-401
    • Strieder, T.G.1    Prummel, M.F.2    Tijssen, J.G.3    Endert, E.4    Wiersinga, W.M.5
  • 47
    • 0042667153 scopus 로고    scopus 로고
    • Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
    • Suzuki A, et al. Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat Genet 2003;34:395-340.
    • (2003) Nat Genet , vol.34 , pp. 395-340
    • Suzuki, A.1
  • 48
    • 0344364566 scopus 로고    scopus 로고
    • An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
    • Tokuhiro S, et al. An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet 2003;35:341-348.
    • (2003) Nat Genet , vol.35 , pp. 341-348
    • Tokuhiro, S.1
  • 49
    • 0034467062 scopus 로고    scopus 로고
    • Citrullination: A small change for a protein with great consequences for rheumatoid arthritis
    • van Venrooij WJ, Pruijn GJ. Citrullination: a small change for a protein with great consequences for rheumatoid arthritis. Arthritis Res 2000;2:249-251.
    • (2000) Arthritis Res , vol.2 , pp. 249-251
    • Van Venrooij, W.J.1    Pruijn, G.J.2
  • 50
    • 1842733194 scopus 로고    scopus 로고
    • A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population
    • Barton A, et al. A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population. Arthritis Rheum 2004;50:1117-1121.
    • (2004) Arthritis Rheum , vol.50 , pp. 1117-1121
    • Barton, A.1
  • 51
    • 7044253358 scopus 로고    scopus 로고
    • Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
    • Smyth D, et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes. 2004; 53:3020-3023.
    • (2004) Diabetes , vol.53 , pp. 3020-3023
    • Smyth, D.1
  • 52
    • 20144388808 scopus 로고    scopus 로고
    • The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a does32 dependent manner but not with HLA shared epitope status
    • in press
    • Lee AT, et al. The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a does32 dependent manner but not with HLA shared epitope status. Genes and Immunity (in press).
    • Genes and Immunity
    • Lee, A.T.1
  • 53
    • 11144292728 scopus 로고    scopus 로고
    • The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis
    • Begovich AB, et al. The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis. Am J Hum Genet 2005; 76: 184-187.
    • (2005) Am J Hum Genet , vol.76 , pp. 184-187
    • Begovich, A.B.1


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